amitriptyline has been researched along with Acute Hypercapnic Respiratory Failure in 6 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " She was on multiple medications including diazepam, oxycodone, and amitriptyline, known to be associated with coma blisters, though she did not overdose on any of them." | 3.78 | Coma blisters with hypoxemic respiratory failure. ( Agarwal, A; Bansal, M; Conner, K, 2012) |
| "Postmorphine Paco2 was significantly higher in the amitriptyline and combination groups at all time points over the 240 min, and in the gabapentin group at 10 and 30 min after morphine injection (P<0." | 1.35 | The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits. ( Garcia-Bournissen, F; Hoshino, N; Ito, S; Kapur, B; Koren, G; Kozer, E; Leombruno, J; Levichek, Z; Taguchi, N, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 2 (33.33) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kozer, E | 1 |
| Levichek, Z | 1 |
| Hoshino, N | 1 |
| Kapur, B | 1 |
| Leombruno, J | 1 |
| Taguchi, N | 1 |
| Garcia-Bournissen, F | 1 |
| Koren, G | 1 |
| Ito, S | 1 |
| Agarwal, A | 1 |
| Bansal, M | 1 |
| Conner, K | 1 |
| Follmer, CH | 1 |
| Lum, BK | 1 |
| Okamoto, K | 1 |
| Umeno, M | 1 |
| Takagi, H | 1 |
| Nagano, S | 1 |
| Takeda, Y | 1 |
| Knudsen, K | 1 |
| Collins, J | 1 |
| Goulding, R | 1 |
6 other studies available for amitriptyline and Acute Hypercapnic Respiratory Failure
| Article | Year |
|---|---|
The effect of amitriptyline, gabapentin, and carbamazepine on morphine-induced hypercarbia in rabbits.
Topics: Amines; Amitriptyline; Analgesics, Opioid; Animals; Anticonvulsants; Antidepressive Agents, Tricycli | 2008 |
Coma blisters with hypoxemic respiratory failure.
Topics: Amitriptyline; Anti-Bacterial Agents; Blister; Coma; Diazepam; Drug Therapy, Combination; Female; Hu | 2012 |
Protective action of diazepam and of sympathomimetic amines against amitryptyline-induced toxicity.
Topics: Amitriptyline; Anesthesia; Animals; Cardiovascular Diseases; Cats; Diazepam; Female; Male; Myocardia | 1982 |
[Case of malignant neuroleptic syndrome caused by an anti-depressive agent, later complicated by respiratory insufficiency and DIC].
Topics: Aged; Amitriptyline; Amoxapine; Disseminated Intravascular Coagulation; Female; Humans; Neuroleptic | 1998 |
[Overdosing with tricyclic antidepressive agent caused acute pulmonary failure].
Topics: Adult; Amitriptyline; Humans; Male; Pulmonary Edema; Radiography; Respiration, Artificial; Respirato | 1992 |
Pulmonary disease after amitriptyline overdosage.
Topics: Amitriptyline; Female; Humans; Respiratory Function Tests; Respiratory Insufficiency; Secobarbital; | 1973 |