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amitriptyline and Acute Confusional Senile Dementia

amitriptyline has been researched along with Acute Confusional Senile Dementia in 10 studies

Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.

Research Excerpts

ExcerptRelevanceReference
" Renal dosing for topiramate, reduction in PIMs/anticholinergic burden, and substituting haloperidol for olanzapine resolved his violent behavior and CD."2.50Capgras delusion with violent behavior in Alzheimer dementia: case analysis with literature review. ( Dawood, A; Kaufman, KR; Newman, NB, 2014)
"Amitriptyline treatment also caused a significant potentiation of non-toxic Aβ monomer with a concomitant decrease in cytotoxic dimer Aβ load, compared to vehicle-treated 3×TgAD controls."1.37Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity. ( Becker, KG; Caroll, J; Chadwick, W; Lehrmann, E; Martin, B; Maudsley, S; Mitchell, N; Park, SS; Wang, L; Wood, WH; Zhang, Y; Zhou, Y, 2011)
"Drug-induced delirium is a common matter in the elderly and anticholinergics, together with a number of different drugs, may significantly contribute to the delirium onset, especially in demented people."1.34Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient. ( Cotroneo, A; De Fazio, P; De Fazio, S; De Sarro, G; Gallelli, L; Gareri, P; Lacava, R, 2007)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19903 (30.00)18.7374
1990's2 (20.00)18.2507
2000's3 (30.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, L1
Olsen, GE1
Klein, JT1
Kapples, KJ1
Huger, FP1
Smith, CP1
Petko, WW1
Cornfeldt, M1
Effland, RC1
Kaufman, KR1
Newman, NB1
Dawood, A1
Chadwick, W1
Mitchell, N1
Caroll, J1
Zhou, Y1
Park, SS1
Wang, L1
Becker, KG1
Zhang, Y1
Lehrmann, E1
Wood, WH1
Martin, B1
Maudsley, S1
Gareri, P1
De Fazio, P1
Cotroneo, A1
Lacava, R1
Gallelli, L1
De Fazio, S1
De Sarro, G1
Reding, MJ1
Young, R1
DiPonte, P1
Engel, PA1
Chapron, D1
Okiishi, CG1
Paradiso, S1
Robinson, RG1
González Moneo, MJ1
Garrido Barral, A1
Jenike, MA1
Asnes, DP1

Reviews

3 reviews available for amitriptyline and Acute Confusional Senile Dementia

ArticleYear
Capgras delusion with violent behavior in Alzheimer dementia: case analysis with literature review.
    Annals of clinical psychiatry : official journal of the American Academy of Clinical Psychiatrists, 2014, Volume: 26, Issue:3

    Topics: Aged; Aggression; Alzheimer Disease; Amitriptyline; Anticonvulsants; Antidepressive Agents, Tricycli

2014
Gender differences in depression associated with neurologic illness: clinical correlates and pharmacologic response.
    The journal of gender-specific medicine : JGSM : the official journal of the Partnership for Women's Health at Columbia, 2001, Volume: 4, Issue:2

    Topics: Alzheimer Disease; Amitriptyline; Antidepressive Agents, Tricyclic; Depression; Epilepsy; Female; Hu

2001
[Latest therapies for treating dementia].
    Atencion primaria, 2002, May-15, Volume: 29, Issue:8

    Topics: Adult; Aged; Alzheimer Disease; Amitriptyline; Antidepressive Agents, Second-Generation; Antidepress

2002

Trials

1 trial available for amitriptyline and Acute Confusional Senile Dementia

ArticleYear
Amitriptyline in Alzheimer's disease.
    Neurology, 1983, Volume: 33, Issue:4

    Topics: Aged; Alzheimer Disease; Amitriptyline; Dementia; Female; Humans; Male; Psychiatric Status Rating Sc

1983

Other Studies

6 other studies available for amitriptyline and Acute Confusional Senile Dementia

ArticleYear
Substituted (pyrroloamino)pyridines: potential agents for the treatment of Alzheimer's disease.
    Journal of medicinal chemistry, 1996, Jan-19, Volume: 39, Issue:2

    Topics: Alzheimer Disease; Animals; Biogenic Amines; In Vitro Techniques; Mice; Pyridines; Quinuclidinyl Ben

1996
Amitriptyline-mediated cognitive enhancement in aged 3×Tg Alzheimer's disease mice is associated with neurogenesis and neurotrophic activity.
    PloS one, 2011, Volume: 6, Issue:6

    Topics: Alzheimer Disease; Amitriptyline; Amyloid beta-Peptides; Animals; Antidepressive Agents, Tricyclic;

2011
Anticholinergic drug-induced delirium in an elderly Alzheimer's dementia patient.
    Archives of gerontology and geriatrics, 2007, Volume: 44 Suppl 1

    Topics: Acute Disease; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Antipsychotic Agents; Cholinergi

2007
Cyclobenzaprine-induced delirium in two octogenarians.
    The Journal of clinical psychiatry, 1993, Volume: 54, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Alzheimer Disease; Amitriptyline; Delirium; Female; Humans; Ma

1993
Use of MAOIs for demented depressed patients.
    The American journal of psychiatry, 1986, Volume: 143, Issue:2

    Topics: Aged; Alzheimer Disease; Amitriptyline; Dementia; Depressive Disorder; Humans; Male; Monoamine Oxida

1986
Psychopharmacology in the aged. Use of major psychotropic medications in treatment of the elderly: case examples.
    Journal of geriatric psychiatry, 1974, Volume: 7, Issue:2

    Topics: Adjustment Disorders; Aged; Alzheimer Disease; Amitriptyline; Benztropine; Bipolar Disorder; Cataton

1974