amitriptyline has been researched along with Acute Brain Injuries in 10 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The severe burning pain, deep pressure-like pain, and deep mechanical allodynia, which presented over the contralateral side to the TBI, were successfully relieved with motor cortex stimulation (MCS)." | 1.33 | Motor cortex stimulation for central pain following a traumatic brain injury. ( Choi, ES; Hong, JT; Lee, SW; Son, BC; Sung, JH, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 2 (20.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kuczynski, A | 1 |
| Crawford, S | 1 |
| Bodell, L | 1 |
| Dewey, D | 1 |
| Barlow, KM | 1 |
| Mahesh, R | 1 |
| Pandey, DK | 1 |
| Katiyar, S | 1 |
| Kukade, G | 1 |
| Viyogi, S | 1 |
| Rudra, A | 1 |
| KRUEGER, H | 1 |
| ZUMPE, V | 1 |
| Son, BC | 1 |
| Lee, SW | 1 |
| Choi, ES | 1 |
| Sung, JH | 1 |
| Hong, JT | 1 |
| Boyeson, MG | 1 |
| Harmon, RL | 1 |
| Jones, JL | 1 |
| Reinhard, DL | 1 |
| Whyte, J | 1 |
| Sandel, ME | 1 |
| Lipper, S | 1 |
| Tuchman, MM | 1 |
| Jackson, RD | 3 |
| Mysiw, WJ | 2 |
| Corrigan, JD | 2 |
| Arnett, JA | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| PLAY GAME: Post-concussion Syndrome Affecting Youth: GABAergic Effects of Melatonin. A Randomized Double-blind Placebo-controlled Trial of MELATONIN[NCT01874847] | Phase 2/Phase 3 | 99 participants (Actual) | Interventional | 2013-09-30 | Active, not recruiting | ||
| Assessment of the Efficacy of Medrol Dose Pack for Post-Concussive Headaches[NCT04685772] | 25 participants (Anticipated) | Observational [Patient Registry] | 2021-04-01 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for amitriptyline and Acute Brain Injuries
| Article | Year |
|---|---|
Treatment of chronic post-traumatic organic brain syndrome with dextroamphetamine: first reported case.
Topics: Accidents, Traffic; Adult; Amitriptyline; Brain Injuries; Chlorpromazine; Dextroamphetamine; Drug Th | 1976 |
Abnormal cortisol dynamics after traumatic brain injury. Lack of utility in predicting agitation or therapeutic response to tricyclic antidepressants.
Topics: Adolescent; Adult; Amitriptyline; Arousal; Brain Injuries; Clinical Trials as Topic; Desipramine; De | 1989 |
8 other studies available for amitriptyline and Acute Brain Injuries
| Article | Year |
|---|---|
Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort.
Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Brain | 2013 |
Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort.
Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Brain | 2013 |
Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort.
Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Brain | 2013 |
Characteristics of post-traumatic headaches in children following mild traumatic brain injury and their response to treatment: a prospective cohort.
Topics: Adolescent; Amitriptyline; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Brain | 2013 |
Effect of anti-depressants on neuro-behavioural consequences following impact accelerated traumatic brain injury in rats.
Topics: Acceleration; Amitriptyline; Animals; Antidepressive Agents; Anxiety; Behavior, Animal; Brain Injuri | 2010 |
[AMITRYPTILINE POISONING. A CONTRIBUTION TO THE CLINICAL PICTURE. PSYCHIATRIC AND PSYCHOLOGICAL TEST STUDIES ON THE PROBLEM OF THE TOXIC BRAIN DEGERERATION SYNDROME].
Topics: Amitriptyline; Antidepressive Agents; Brain; Brain Damage, Chronic; Brain Diseases; Brain Injuries; | 1965 |
Motor cortex stimulation for central pain following a traumatic brain injury.
Topics: Accidental Falls; Adult; Amines; Amitriptyline; Analgesics, Non-Narcotic; Aphasia, Broca; Brain Inju | 2006 |
Comparative effects of fluoxetine, amitriptyline and serotonin on functional motor recovery after sensorimotor cortex injury.
Topics: Amitriptyline; Brain Injuries; Fluoxetine; Motor Cortex; Psychomotor Performance; Serotonin; Time Fa | 1994 |
Improved arousal and initiation following tricyclic antidepressant use in severe brain injury.
Topics: Activities of Daily Living; Adult; Amitriptyline; Antidepressive Agents, Tricyclic; Arousal; Brain I | 1996 |
Amitriptyline for post-traumatic agitation.
Topics: Adolescent; Adult; Amitriptyline; Amnesia; Brain Injuries; Cognition; Female; Humans; Male; Middle A | 1988 |
Amitriptyline for agitation in head injury.
Topics: Adult; Aggression; Amitriptyline; Brain Injuries; Female; Humans; Psychomotor Agitation | 1985 |