amitriptyline has been researched along with Acquired Metabolic Diseases, Brain in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Importantly, chronic administration of antidepressant amitriptyline partially or completely restored these changes in serotonergic and BDNF systems, respectively." | 1.42 | NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain - Restoration by chronic amitriptyline. ( Anier, K; Aonurm-Helm, A; Castrén, E; Järv, J; Rantamäki, T; Stepanov, V; Zharkovsky, A; Zharkovsky, T, 2015) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aonurm-Helm, A | 1 |
| Anier, K | 1 |
| Zharkovsky, T | 1 |
| Castrén, E | 1 |
| Rantamäki, T | 1 |
| Stepanov, V | 1 |
| Järv, J | 1 |
| Zharkovsky, A | 1 |
1 other study available for amitriptyline and Acquired Metabolic Diseases, Brain
| Article | Year |
|---|---|
NCAM-deficient mice show prominent abnormalities in serotonergic and BDNF systems in brain - Restoration by chronic amitriptyline.
Topics: Adrenergic Uptake Inhibitors; Amitriptyline; Animals; Brain; Brain Diseases, Metabolic; Brain-Derive | 2015 |