amitriptyline has been researched along with Acid Ceramidase Deficiency in 1 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "No treatments for Farber disease are clinically available, and affected patients have a severely shortened lifespan." | 1.51 | Acid Sphingomyelinase Deficiency Ameliorates Farber Disease. ( Becker, KA; Beckmann, N; Carpinteiro, A; Edwards, MJ; Gulbins, E; Kadow, S; Kleuser, B; Kramer, M; Kühn, C; Schulz-Schaeffer, WJ; Schumacher, F, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beckmann, N | 1 |
| Becker, KA | 1 |
| Kadow, S | 1 |
| Schumacher, F | 1 |
| Kramer, M | 1 |
| Kühn, C | 1 |
| Schulz-Schaeffer, WJ | 1 |
| Edwards, MJ | 1 |
| Kleuser, B | 1 |
| Gulbins, E | 1 |
| Carpinteiro, A | 1 |
1 other study available for amitriptyline and Acid Ceramidase Deficiency
| Article | Year |
|---|---|
Acid Sphingomyelinase Deficiency Ameliorates Farber Disease.
Topics: Acid Ceramidase; Amitriptyline; Animals; Ceramides; Cytokines; Farber Lipogranulomatosis; Mice, Inbr | 2019 |