amitriptyline has been researched along with Abnormalities, Drug-Induced in 14 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
Abnormalities, Drug-Induced: Congenital abnormalities caused by medicinal substances or drugs of abuse given to or taken by the mother, or to which she is inadvertently exposed during the manufacture of such substances. The concept excludes abnormalities resulting from exposure to non-medicinal chemicals in the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Thanatophoric dwarfism is not as rare as once thought." | 1.28 | Thanatophoric dwarfism; drugs and antenatal diagnosis; a case report. ( Meehan, FP; Rafla, NM, 1991) |
| "This case of bilateral clinical anophthalmia presents a host of interrelated drug reactions and potential teratogenic factors." | 1.26 | Bilateral clinical anophthalmia: drugs as potential factors. ( Golden, SM; Perman, KI, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (78.57) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Moreira, A | 1 |
| Barbin, C | 1 |
| Martinez, H | 1 |
| Aly, A | 1 |
| Fonseca, R | 1 |
| Beyer, BK | 1 |
| Guram, MS | 2 |
| Geber, WF | 2 |
| Gill, TS | 1 |
| Golden, SM | 1 |
| Perman, KI | 1 |
| Shuey, DL | 1 |
| Sadler, TW | 1 |
| Lauder, JM | 1 |
| Rafla, NM | 1 |
| Meehan, FP | 1 |
| Flannery, DB | 1 |
| Idänpään-Heikkilä, J | 1 |
| Saxén, L | 1 |
| Morrow, AW | 2 |
| Hill, RM | 1 |
| Verniaud, WM | 1 |
| Horning, MG | 1 |
| McCulley, LB | 1 |
| Morgan, NF | 1 |
| Kuenssberg, EV | 1 |
| Knox, JD | 1 |
| Freeman, R | 1 |
| Pitt, DB | 1 |
| Wilkins, GD | 1 |
14 other studies available for amitriptyline and Abnormalities, Drug-Induced
| Article | Year |
|---|---|
Maternal use of cyclobenzaprine (Flexeril) may induce ductal closure and persistent pulmonary hypertension in neonates.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Antidepressive Agents, Tricyclic; Ductus Arteriosus; Fem | 2014 |
Incidence and potentiation of external and internal fetal anomalies resulting from chlordiazepoxide and amitriptyline alone and in combination.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Animals; Chlordiazepoxide; Cricetinae; Drug Synergism; E | 1984 |
Comparative teratogenicity of chlordiazepoxide, amitriptyline, and a combination of the two compounds in the fetal hamster.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Animals; Chlordiazepoxide; Cricetinae; Dose-Response Rel | 1982 |
Bilateral clinical anophthalmia: drugs as potential factors.
Topics: Abnormalities, Drug-Induced; Adult; Amitriptyline; Anophthalmos; Dicyclomine; Drug Combinations; Dru | 1980 |
Serotonin as a regulator of craniofacial morphogenesis: site specific malformations following exposure to serotonin uptake inhibitors.
Topics: 1-Naphthylamine; Abnormalities, Drug-Induced; Amitriptyline; Animals; Cell Death; Cell Division; Epi | 1992 |
Thanatophoric dwarfism; drugs and antenatal diagnosis; a case report.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Female; Humans; Infant, Newborn; Male; Phenobarbital; Ph | 1991 |
Syndrome of imperforate oropharynx with costovertebral and auricular anomalies.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Ear, External; Female; Humans; Infant, Newborn; Infant, | 1989 |
Rachelefsky GS, Flynt JW Jr,+FLYNT JW JR, Ebbin AJ, Wilson MG, Banister P, Dafoe C, Smith ES, Miller J:Possible teratogenicity of tricyclic antidepressants.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Antidepressive Agents; Female; Humans; Imipramine; Infan | 1972 |
Possible teratogenicity of imipramine-chloropyramine.
Topics: Abnormalities, Drug-Induced; Adult; Amitriptyline; Antidepressive Agents; Benzyl Compounds; Drug Com | 1973 |
Imipramine and congenital abnormalities.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Female; Humans; Imipramine; Infant, Newborn; Limb Deform | 1972 |
Infants exposed in utero to antiepileptic drugs. A prospective study.
Topics: Abnormalities, Drug-Induced; Adolescent; Adult; Amitriptyline; Amniotic Fluid; Anticonvulsants; Chro | 1974 |
Imipramine in pregnancy.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Amitriptyline; Female; Humans; Imipramine; Infan | 1972 |
Limb deformities: possible association with drugs.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Arm; Female; Humans; Infant, Newborn; Leg; Male; Pregnan | 1972 |
Limb deformities associated with iminodibenzyl hydrochloride.
Topics: Abnormalities, Drug-Induced; Amitriptyline; Drug and Narcotic Control; Ectromelia; Female; Humans; I | 1972 |