amitriptyline has been researched along with ALS - Amyotrophic Lateral Sclerosis in 10 studies
Amitriptyline: Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
amitriptyline : An organic tricyclic compound that is 10,11-dihydro-5H-dibenzo[a,d][7]annulene substituted by a 3-(dimethylamino)propylidene group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "There were 1948 treatment histories for modafinil and 1394 treatment reports for amitriptyline reported across five PatientsLikeMe communities (multiple sclerosis, Parkinson's disease, mood conditions, fibromyalgia/chronic fatigue syndrome, and amyotrophic lateral sclerosis)." | 3.77 | Patient-reported outcomes as a source of evidence in off-label prescribing: analysis of data from PatientsLikeMe. ( Frost, J; Heywood, J; Okun, S; Vaughan, T; Wicks, P, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (50.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 1 (10.00) | 29.6817 |
| 2010's | 3 (30.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Banks, DB | 1 |
| Chan, GN | 1 |
| Evans, RA | 1 |
| Miller, DS | 1 |
| Cannon, RE | 1 |
| Pinto, S | 1 |
| Gromicho, M | 1 |
| de Carvalho, M | 1 |
| Sawada, J | 1 |
| Yamashita, T | 1 |
| Aizawa, H | 1 |
| Aburakawa, Y | 1 |
| Hasebe, N | 1 |
| Kwak, S | 1 |
| Frost, J | 1 |
| Okun, S | 1 |
| Vaughan, T | 1 |
| Heywood, J | 1 |
| Wicks, P | 1 |
| Smith, RA | 1 |
| Norris, FH | 1 |
| Goldblatt, D | 1 |
| Leys, D | 1 |
| Petit, H | 1 |
| Pascuzzi, RM | 1 |
| Dorman, JD | 1 |
10 other studies available for amitriptyline and ALS - Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Lysophosphatidic acid and amitriptyline signal through LPA1R to reduce P-glycoprotein transport at the blood-brain barrier.
Topics: Amitriptyline; Amyotrophic Lateral Sclerosis; Animals; Antidepressive Agents, Tricyclic; ATP Binding | 2018 |
Sialorrhoea and reversals in ALS functional rating scale.
Topics: Aged; Amitriptyline; Amyotrophic Lateral Sclerosis; Atropine; Cholinergic Antagonists; Deglutition D | 2017 |
Effects of antidepressants on GluR2 Q/R site-RNA editing in modified HeLa cell line.
Topics: Adenosine Deaminase; Amitriptyline; Amyotrophic Lateral Sclerosis; Antidepressive Agents; Arginine; | 2009 |
Patient-reported outcomes as a source of evidence in off-label prescribing: analysis of data from PatientsLikeMe.
Topics: Amitriptyline; Amyotrophic Lateral Sclerosis; Benzhydryl Compounds; Cognition Disorders; Community N | 2011 |
Symptomatic care of patients with amyotrophic lateral sclerosis.
Topics: Amitriptyline; Amyotrophic Lateral Sclerosis; Aphonia; Braces; Deglutition Disorders; Edetic Acid; E | 1975 |
Treatment of amyotrophic lateral sclerosis.
Topics: Aging; Amitriptyline; Amyotrophic Lateral Sclerosis; Baclofen; Braces; Dantrolene; Deglutition Disor | 1977 |
Clinical signs of amyotrophic lateral sclerosis developing after polyradiculoneuropathy associated with amitriptyline.
Topics: Amitriptyline; Amyotrophic Lateral Sclerosis; Drug Overdose; Humans; Polyradiculoneuropathy; Reflex, | 1990 |
Amyotrophic lateral sclerosis.
Topics: Adult; Aged; Amitriptyline; Amyotrophic Lateral Sclerosis; Cholinesterase Inhibitors; Diagnosis, Dif | 1988 |
Amitriptyline in amyotrophic lateral sclerosis.
Topics: Adult; Amitriptyline; Amyotrophic Lateral Sclerosis; Emotions; Humans; Male; Methylphenidate; Parkin | 1985 |
Treatment of amyotrophic lateral sclerosis.
Topics: Amitriptyline; Amyotrophic Lateral Sclerosis; Humans | 1969 |