Page last updated: 2024-10-22

amiodarone and Thyroid Diseases

amiodarone has been researched along with Thyroid Diseases in 156 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Thyroid Diseases: Pathological processes involving the THYROID GLAND.

Research Excerpts

ExcerptRelevanceReference
"We aimed to evaluate the impact of 8weeks of amiodarone treatment on thyroid function in patients with atrial fibrillation (AF) undergoing catheter ablation in a randomised, double-blind clinical trial."9.22Short-term amiodarone treatment for atrial fibrillation after catheter ablation induces a transient thyroid dysfunction: Results from the placebo-controlled, randomized AMIO-CAT trial. ( Chen, X; Darkner, S; Diederichsen, SZ; Feldt-Rasmussen, U; Hansen, J; Johannesen, A; Pehrson, S; Svendsen, JH, 2016)
"We compared the efficacy and safety of amiodarone and dronedarone in patients with persistent atrial fibrillation (AF)."9.14A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study. ( Davy, JM; De Ferrari, GM; Le Heuzey, JY; Radzik, D; Santini, M; Zhu, J, 2010)
"This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated."9.12Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007)
"In 232 Japanese patients receiving long-term amiodarone therapy for life-threatening ventricular tachyarrhythmias, hyperthyroidism and hypothyroidism developed in 29 patients (12."7.71Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan. ( Hagiwara, N; Kasanuki, H; Matsuda, N; Sato, K; Shiga, T; Shoda, M; Wakaumi, M, 2001)
"Amiodarone may induce hyper- or hypothyroidism."7.70High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment. ( Balestrieri, A; Lai, ME; Loviselli, A; Mandas, A; Mariotti, S; Martino, E; Murenu, S; Sau, F; Vacquer, S; Valentino, L, 1999)
"Because little has been published on early effects of treatment with amiodarone on thyroid function, we studied serum total and free thyroid hormone, reverse T3, and TSH levels in patients with cardiac arrhythmias during the first 10 days of treatment with a loading dose of amiodarone by iv infusion."7.69Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia. ( Berti, S; Biagini, A; Bonini, R; Carpi, A; Chopra, IJ; Clerico, A; Iervasi, G; Manfredi, C; Palmieri, C; Ravani, M, 1997)
"A rare case of amiodarone-iodine-induced thyrotoxicosis (AIIT) associated with nonthyroidal illness is reported."7.67Diagnosis of amiodarone-iodine-induced thyrotoxicosis(AIIT) associated with severe nonthyroidal illness. ( Balestrieri, A; Balzano, S; Bartalena, L; Cherchi, A; Martino, E; Ruscazio, M; Sau, F, 1987)
"Amiodarone, an iodine-rich drug widely used for the treatment of cardiac tachyarrhythmias, may induce either hyperthyroidism or hypothyroidism."7.67Amiodarone iodine-induced hypothyroidism: risk factors and follow-up in 28 cases. ( Aghini-Lombardi, F; Bambini, G; Bartalena, L; Braverman, LE; Ceccarelli, C; Lenziardi, M; Mariotti, S; Martino, E; Pinchera, A; Safran, M, 1987)
"Amiodarone was administered to 154 patients who had sustained, symptomatic ventricular tachycardia (VT) (n = 118) or a cardiac arrest (n = 36) and who were refractory to conventional antiarrhythmic drugs."7.66Long-term efficacy and toxicity of high-dose amiodarone therapy for ventricular tachycardia or ventricular fibrillation. ( Bhandari, A; Keung, E; Malone, P; Morady, F; Sauve, MJ; Scheinman, MM; Schwartz, AB; Shen, EN; Sung, RJ, 1983)
"Iodide-induced hypothyroidism has also been observed in patients with a history of postpartum thyroiditis, in euthyroid patients after a previous episode of subacute thyroiditis, and in patients treated with recombinant interferon-alpha who developed transient thyroid dysfunction during interferon-a treatment."6.41Iodine-Induced hypothyroidism. ( Georgopoulos, N; Kyriazopoulou, V; Markou, K; Vagenakis, AG, 2001)
"Iodine induced hyperthyroidism is frequently observed in patients affected by euthyroid iodine deficient goiter when suddenly exposed to excess iodine."6.41Iodine excess and hyperthyroidism. ( Roti, E; Uberti, ED, 2001)
" A dose-response relationship was observed between the 1-year accumulated amiodarone dose and the subsequent 5-year cumulative incidence of thyroid dysfunction."5.91Incidence of thyroid dysfunction following initiation of amiodarone treatment in patients with and without heart failure: a nationwide cohort study. ( Ali, SA; Butt, JH; Ersbøll, M; Fosbøl, E; Gustafsson, F; Jøns, C; Kristensen, SL; Køber, L; Mogensen, UM; Rørth, R; Selmer, C; Vinding, NE; Weeke, PE; Westergaard, LM, 2023)
" These data show that iodine released by amiodarone has a bioavailability different from that of NaI."5.28Changes in 127I mice thyroid follicle studied by analytical ion microscopy: a key for the comprehension of amiodarone-induced thyroid diseases. ( Briançon, C; Fragu, P; Halpern, S; Telenczak, P, 1990)
"Amiodarone, a drug that has electrophysiologic actions resembling those of hypothyroidism, increases serum levels of T4 and reverse T3 (rT3) and decreases T3."5.27Amiodarone, thyroid hormone indexes, and altered thyroid function: long-term serial effects in patients with cardiac arrhythmias. ( Callahan, B; Hendrickson, JA; Hershman, JM; Nademanee, K; Singh, BN, 1986)
"We aimed to evaluate the impact of 8weeks of amiodarone treatment on thyroid function in patients with atrial fibrillation (AF) undergoing catheter ablation in a randomised, double-blind clinical trial."5.22Short-term amiodarone treatment for atrial fibrillation after catheter ablation induces a transient thyroid dysfunction: Results from the placebo-controlled, randomized AMIO-CAT trial. ( Chen, X; Darkner, S; Diederichsen, SZ; Feldt-Rasmussen, U; Hansen, J; Johannesen, A; Pehrson, S; Svendsen, JH, 2016)
"In SCD-HeFT (Sudden Cardiac Death in Heart Failure Trial), which randomized patients with ischemic or nonischemic HF to placebo or amiodarone or implantable cardioverter-defibrillator therapy, thyroid-stimulating hormone (TSH) was measured at baseline and at 6-month intervals throughout the 5-year study."5.17Thyroid function in heart failure and impact on mortality. ( Anderson, J; Bardy, GH; Hellkamp, AS; Johnson, GW; Lee, KL; Mark, DB; Mitchell, JE; Poole, JE, 2013)
"We compared the efficacy and safety of amiodarone and dronedarone in patients with persistent atrial fibrillation (AF)."5.14A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study. ( Davy, JM; De Ferrari, GM; Le Heuzey, JY; Radzik, D; Santini, M; Zhu, J, 2010)
"This is a substudy of a prospective randomized controlled trial (SAFE-Trial) in which amiodarone, sotalol, and placebo for persistent atrial fibrillation were evaluated."5.12Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation. ( Batcher, EL; Hershman, JM; Reda, DJ; Singh, BN; Singh, SN; Tang, XC, 2007)
"Thyroid disorders and eye diseases are interrelated through several mechanisms thus, awareness of this relation has a great impact on early diagnosis and treatment."5.05Thyroid and Eye: Where They Meet in Clinical Practice. ( El-Eshmawy, MM; Shahin, M, 2020)
"Reports published with the following search terms were searched:, thyroid, hypothyroidism, hyperthyroidism, subclinical hyperthyroidism, subclinical hypothyroidism, levothyroxine, triiodothyronine, antithyroid drugs, radioiodine, deiodinases, clinical symptoms, heart rate, HF, systolic function, diastolic function, systemic vascular resistance, endothelial function, amiodarone and atrial fibrillation."4.88Mechanisms in endocrinology: Heart failure and thyroid dysfunction. ( Biondi, B, 2012)
"To summarize the mechanisms of iodine-induced hypothyroidism and hyperthyroidism, identify the risk factors for thyroid dysfunction following an iodine load, and summarize the major sources of excess iodine exposure."4.88Iodine-induced thyroid dysfunction. ( Braverman, LE; Leung, AM, 2012)
" More recently, it has been suggested that rhTSH is useful for treatment of multinodular goiter and amiodarone-induced thyrotoxicosis, as well as for diagnosis of congenital hypothyroidism."4.84Recombinant human thyrotropin in the management of thyroid disorders. ( Graf, H; Paz-Filho, GJ, 2008)
" Treatment with amiodarone may lead to changes in thyroid tests results and to development of hypothyroidism or thyrotoxicosis."4.82[Thyroid and cardiovascular disorders]. ( Gajek, J; Zyśko, D, 2004)
"Amiodarone, an anti-ischaemic and anti-arrhythmic drug, has been the object of numerous studies and seems to be highly effective in the treatment of severe ventricular arrhythmias on dilated cardiomyopathies, as well as of hypertrophic or ischaemic heart diseases."4.78[Does amiodarone have a benefit effect on mortality?]. ( Kahn, JC; Pathé, M, 1991)
" An increase of the thyroid iodine content (TIC) is observed in all patients at the exception of those who develop hypothyroidism under treatment."4.77[Thyroid function and amiodarone. Consequences on dysthyroidism testing]. ( Fragu, P; Schlumberger, M, 1985)
" Ultrasound has a role in the investigation of Graves' disease, subacute thyroiditis, gestational thyrotoxicosis, postpartum thyroiditis, amiodarone thyrotoxicosis and goiter with or without adenoma, but adenomas are usually investigated by endocrine surgeons in Sweden."4.12[Thyroid ultrasound and its role in the investigation of thyroid disease]. ( Almquist, M; Koutouridou, E; Lantz, M; Mijovic, Z; Pellby, D; Planck, T; Tsoumani, K, 2022)
"Amiodarone is used in patients with arrhythmias, but thyroid dysfunction [amiodarone-induced thyrotoxicosis (AIT) or amiodarone-induced hypothyroidism (AIH)] is a common adverse effect."3.91The Effects of Amiodarone on Thyroid Function in Pediatric and Young Adult Patients. ( Barrett, B; Bauer, AJ; Hawkes, CP; Isaza, A, 2019)
" This study was intended to determine whether CRP levels could differentiate between inflammatory and noninflammatory thyroid conditions, especially between type II inflammatory amiodarone-induced thyrotoxicosis (AIT) and type I iodine-induced AIT."3.72The prevalence of elevated serum C-reactive protein levels in inflammatory and noninflammatory thyroid disease. ( Bogazzi, F; Braverman, LE; Brogioni, S; Lazarus, JH; Martino, E; Pardini, E; Parkes, AB; Pearce, EN; Pellegrini, G; Pinchera, A, 2003)
"During 1 year of amiodarone intake development of amiodarone-associated thyroid dysfunction was observed in 25% of patients (hypothyroidism and thyrotoxicosis in 19."3.72[Amiodarone-associated thyroid dysfunction: prevalence and possibilities of correction]. ( Bakalov, SA; Golitsin, SP; Molashenko, NV; Platonova, NM; Serdiuk, SE; Soboleva, VA; Sviridenko, NIu, 2004)
"In 232 Japanese patients receiving long-term amiodarone therapy for life-threatening ventricular tachyarrhythmias, hyperthyroidism and hypothyroidism developed in 29 patients (12."3.71Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan. ( Hagiwara, N; Kasanuki, H; Matsuda, N; Sato, K; Shiga, T; Shoda, M; Wakaumi, M, 2001)
"Amiodarone may induce hyper- or hypothyroidism."3.70High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment. ( Balestrieri, A; Lai, ME; Loviselli, A; Mandas, A; Mariotti, S; Martino, E; Murenu, S; Sau, F; Vacquer, S; Valentino, L, 1999)
"Because little has been published on early effects of treatment with amiodarone on thyroid function, we studied serum total and free thyroid hormone, reverse T3, and TSH levels in patients with cardiac arrhythmias during the first 10 days of treatment with a loading dose of amiodarone by iv infusion."3.69Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia. ( Berti, S; Biagini, A; Bonini, R; Carpi, A; Chopra, IJ; Clerico, A; Iervasi, G; Manfredi, C; Palmieri, C; Ravani, M, 1997)
"Plasma iodine was below 40 micrograms/l in 57 (7%) patients, most of whom had hypothyroidism; 40-80 micrograms/l in 439 (55%) patients, most of whom had normal thyroid hormone function; 80-250 micrograms/l in 240 (30%) patients, most of whom had hyperthyroidism; and above 250 micrograms/l in 63 (8%) patients, almost all of whom had iodine overload caused by iodinated drugs, particularly amiodarone, resulting in euthyroidism (24%), hyperthyroidism (36%), and hypothyroidism (16%)."3.68Use of plasma iodine assay for diagnosing thyroid disorders. ( Allain, P; Barbot, N; Berre, S; Bigorgne, JC; Krari, N; Lainé-Cessac, P; Le Bouil, A; Rohmer, V, 1993)
"To assess the incidence of adverse effects associated with long-term amiodarone therapy, we reviewed the records of 217 consecutive patients who were treated for refractory arrhythmia."3.67Side effects and complications of amiodarone therapy. ( Lown, B; Podrid, PJ; Raeder, EA, 1985)
"A rare case of amiodarone-iodine-induced thyrotoxicosis (AIIT) associated with nonthyroidal illness is reported."3.67Diagnosis of amiodarone-iodine-induced thyrotoxicosis(AIIT) associated with severe nonthyroidal illness. ( Balestrieri, A; Balzano, S; Bartalena, L; Cherchi, A; Martino, E; Ruscazio, M; Sau, F, 1987)
"Amiodarone, an iodine-rich drug widely used for the treatment of cardiac tachyarrhythmias, may induce either hyperthyroidism or hypothyroidism."3.67Amiodarone iodine-induced hypothyroidism: risk factors and follow-up in 28 cases. ( Aghini-Lombardi, F; Bambini, G; Bartalena, L; Braverman, LE; Ceccarelli, C; Lenziardi, M; Mariotti, S; Martino, E; Pinchera, A; Safran, M, 1987)
"In the face of the recent introduction of beta-blockers and calcium inhibitors, the author examines the role of Amiodarone, Perhexiline and Molsidomine in the treatment of angina pectoris."3.66[The classic anti-anginal agents and molsidomine]. ( Vacheron, A, 1983)
" Both, hypo- and hyperthyroidism can occur, probably as a result of the iodine overload on a preexisting thyroid disorder."3.66Amiodarone and the thyroid gland. A review. ( Jonckheer, MH, 1981)
"Amiodarone was administered to 154 patients who had sustained, symptomatic ventricular tachycardia (VT) (n = 118) or a cardiac arrest (n = 36) and who were refractory to conventional antiarrhythmic drugs."3.66Long-term efficacy and toxicity of high-dose amiodarone therapy for ventricular tachycardia or ventricular fibrillation. ( Bhandari, A; Keung, E; Malone, P; Morady, F; Sauve, MJ; Scheinman, MM; Schwartz, AB; Shen, EN; Sung, RJ, 1983)
"This study suggests that Tc-99m sestamibi may be an alternative tracer for thyroid scintigraphy and uptake measurement of patients on chronic use of amiodarone."2.75Tc-99m sestamibi thyroid imaging in patients on chronic amiodarone treatment: a comparison with Tc-99m pertechnetate imaging. ( Amorim, BJ; Camargo, EE; de Almeida, EA; de Oliveira Santos, A; Etchebehere, EC; Guariento, MH; Lima, MC; Oki, GC; Ramos, CD; Tambascia, MA; Zantut-Wittmann, DE, 2010)
"Amiodarone is a class III antiarrhythmic drug containing 37% iodine by weight, with a structure similar to that of thyroid hormones."2.72Evaluation and Treatment of Amiodarone-Induced Thyroid Disorders. ( Burman, KD; Wartofsky, L; Ylli, D, 2021)
"Amiodarone was searched using the terms adverse effects, hypothyroidism, myxedema, hyperthyroidism, thyroid storm, atrial fibrillation, ventricular arrhythmia, and electrical storm."2.61Amiodarone and thyroid physiology, pathophysiology, diagnosis and management. ( Bianco, AC; McAninch, EA; Sharma, PS; Trohman, RG, 2019)
"Amiodarone is an antiarrhythmic drug frequently used in everyday clinical practice."2.53[Clinical procedure in amiodarone-induced thyroid dysfunction]. ( Cygankiewicz, I; Kosmalski, M; Michalak, R; Ptaszyński, P; Różycka-Kosmalska, M; Wranicz, JK; Zieleniewski, W, 2016)
"Amiodarone is an effective anti-arrhythmic agent for control of various life threatening ventricular tachyarrhythmias but may give Various side effects."2.48Amiodarone therapy: don't forget thyroid. ( Fatima, N; Sajjad, Z, 2012)
"Dronedarone was approved in 2009 for the treatment of patients with atrial fibrillation."2.46Effects of amiodarone therapy on thyroid function. ( Cohen-Lehman, J; Dahl, P; Danzi, S; Klein, I, 2010)
"Triiodothyronine (T3) has no role in the treatment of primary hypothyroidism."2.45Management of thyroid disorders in primary care: challenges and controversies. ( Todd, CH, 2009)
"Dronedarone appears to be an alternative but less-effective anti-arrhythmic agent and it does not have adverse effects on thyroid function."2.45Benzofuran derivatives and the thyroid. ( Han, TS; Vanderpump, MP; Williams, GR, 2009)
"Amiodarone is a frequently used antiarrhythmic drug with a high antiarrhythmic potency."2.44[Thyroid and treatment with amiodarone diagnosis, therapy and clinical management]. ( Mikosch, P, 2008)
"Hypothyroidism is a well defined clinical situation managable thanks to common guidelines."2.42[Amiodarone and thyroid dysfunction: a pending problem]. ( Perazza, L; Scardi, S, 2003)
" Here, we discuss safety issues relating to the long-term use of oral amiodarone in adults."2.42Using oral amiodarone safely. ( , 2003)
"Amiodarone is a benzofuranic-derivative iodine-rich drug widely used for the treatment of tachyarrhythmias and, to a lesser extent, of ischemic heart disease."2.41The effects of amiodarone on the thyroid. ( Bartalena, L; Bogazzi, F; Braverman, LE; Martino, E, 2001)
"Iodine induced hyperthyroidism is frequently observed in patients affected by euthyroid iodine deficient goiter when suddenly exposed to excess iodine."2.41Iodine excess and hyperthyroidism. ( Roti, E; Uberti, ED, 2001)
"Iodide-induced hypothyroidism has also been observed in patients with a history of postpartum thyroiditis, in euthyroid patients after a previous episode of subacute thyroiditis, and in patients treated with recombinant interferon-alpha who developed transient thyroid dysfunction during interferon-a treatment."2.41Iodine-Induced hypothyroidism. ( Georgopoulos, N; Kyriazopoulou, V; Markou, K; Vagenakis, AG, 2001)
"Amiodarone is a highly effective antiarrhythmic agent."2.40[Follow-up of patients treated by amiodarone]. ( Kulbertus, H; Lancellotti, P; Mélon, P, 1998)
"Aggravation of cardiac arrhythmias occurs but serious arrhythmias are caused in less than 5% of patients."2.37Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects. ( Heger, JJ; Prystowsky, EN; Zipes, DP, 1984)
" A dose-response relationship was observed between the 1-year accumulated amiodarone dose and the subsequent 5-year cumulative incidence of thyroid dysfunction."1.91Incidence of thyroid dysfunction following initiation of amiodarone treatment in patients with and without heart failure: a nationwide cohort study. ( Ali, SA; Butt, JH; Ersbøll, M; Fosbøl, E; Gustafsson, F; Jøns, C; Kristensen, SL; Køber, L; Mogensen, UM; Rørth, R; Selmer, C; Vinding, NE; Weeke, PE; Westergaard, LM, 2023)
"Amiodarone is a widely used anti-arrythmic drug with considerable potential to cause thyroid dysfunction because of its 35% iodine content."1.33[The effects of amiodaron on the thyroid function]. ( Kucharczyk, A; Kucharczyk, P; Michałkiewicz, D, 2006)
"Noncardiovascular adverse effects associated with amiodarone result in substantial morbidity."1.29Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone. ( Follin, SL; Ordelova, A; Tisdale, JE; Webb, CR, 1995)
" These data show that iodine released by amiodarone has a bioavailability different from that of NaI."1.28Changes in 127I mice thyroid follicle studied by analytical ion microscopy: a key for the comprehension of amiodarone-induced thyroid diseases. ( Briançon, C; Fragu, P; Halpern, S; Telenczak, P, 1990)
"Hypothyroidism was diagnosed in 11 patients (12%), and a further 11 had tests consistent with a "failing thyroid."1.27Effect of amiodarone on thyroid hormone economy. ( Glick, S; Posner, J; Sobel, RJ, 1984)
"Hyperthyroidism was a more frequent (9."1.27Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy. ( Aghini-Lombardi, F; Aronin, N; Fay, M; Haffajee, C; Lenziardi, M; Macchia, E; Martino, E; Pacchiarotti, A; Rajatanavin, R; Safran, M, 1984)
"Amiodarone is a very active antiarrhythmic agent, but true incidence of Amiodarone-related side effects is still questionable."1.27Side effects during therapy with low dosage amiodarone. ( Beck Peccoz, P; Ferrario, G; Galletti, F; Giani, P; Landolina, M; Maggioni, AP; Piscitelli, G; Tognoni, G; Volpi, A, 1984)
"Amiodarone, a drug that has electrophysiologic actions resembling those of hypothyroidism, increases serum levels of T4 and reverse T3 (rT3) and decreases T3."1.27Amiodarone, thyroid hormone indexes, and altered thyroid function: long-term serial effects in patients with cardiac arrhythmias. ( Callahan, B; Hendrickson, JA; Hershman, JM; Nademanee, K; Singh, BN, 1986)
"A physiological dose of iodine is necessary for thyroid hormonogenesis, but in pharmacological dosage it is a danger."1.26[Iatrogenic thyroid pathology]. ( Léger, AF; Savoie, JC, 1977)
"Amiodarone is a drug which is frequently used in cardiology, and which can lead to the appearance of hyper- of hypo-thyroidism in certain cases."1.26[Amiodarone and thyroid function]. ( Bernard, R; Blockx, P; Broeckaert, I; Jonckheer, MH, 1976)

Research

Studies (156)

TimeframeStudies, this research(%)All Research%
pre-199061 (39.10)18.7374
1990's29 (18.59)18.2507
2000's33 (21.15)29.6817
2010's26 (16.67)24.3611
2020's7 (4.49)2.80

Authors

AuthorsStudies
Lantz, M1
Almquist, M1
Koutouridou, E1
Pellby, D1
Planck, T1
Tsoumani, K1
Mijovic, Z1
Ali, SA2
Ersbøll, M2
Vinding, NE2
Butt, JH2
Rørth, R2
Selmer, C2
Westergaard, LM2
Mogensen, UM2
Weeke, PE2
Jøns, C2
Gustafsson, F2
Fosbøl, E2
Køber, L2
Kristensen, SL2
Kupnovytska, I1
Virstiuk, N1
Danyliuk, O1
Luchko, O1
Kocherzhat, O1
Goundan, PN1
Lee, SL1
Ylli, D2
Wartofsky, L3
Burman, KD4
Sukor, N1
Lachumanan, D1
Kamaruddin, NA1
Elnaggar, MN1
Jbeili, K1
Nik-Hussin, N1
Kozhippally, M1
Pappachan, JM1
Trohman, RG1
Sharma, PS1
McAninch, EA1
Bianco, AC1
Tisdale, JE2
El-Eshmawy, MM1
Shahin, M1
Barrett, B1
Hawkes, CP1
Isaza, A1
Bauer, AJ1
Mitchell, JE1
Hellkamp, AS1
Mark, DB1
Anderson, J1
Johnson, GW1
Poole, JE1
Lee, KL1
Bardy, GH1
Lakatos, P1
Austin, PC1
Park-Wyllie, LY1
Juurlink, DN1
Klein, I2
Danzi, S2
Różycka-Kosmalska, M1
Michalak, R1
Kosmalski, M1
Ptaszyński, P1
Wranicz, JK1
Zieleniewski, W1
Cygankiewicz, I1
Diederichsen, SZ1
Darkner, S1
Chen, X1
Johannesen, A1
Pehrson, S1
Hansen, J1
Feldt-Rasmussen, U1
Svendsen, JH1
Huang, CJ1
Tseng, CL1
Chu, CH1
Huang, DF1
Huang, CC1
Lin, LY1
Rankin, S1
Elder, DH1
Ogston, S1
George, J1
Lang, CC1
Choy, AM1
Han, TS1
Williams, GR1
Vanderpump, MP1
Piga, M1
Serra, A1
Boi, F1
Tanda, ML2
Martino, E11
Mariotti, S3
Paz-Filho, GJ1
Graf, H1
Kim, DD1
Young, S1
Cutfield, R1
Kimura, H1
Kato, Y1
Shimizu, S1
Takano, K1
Sato, K2
Cohen-Lehman, J1
Dahl, P1
Todd, CH1
Oki, GC1
Zantut-Wittmann, DE1
de Oliveira Santos, A1
Guariento, MH1
Tambascia, MA1
de Almeida, EA1
Amorim, BJ1
Lima, MC1
Etchebehere, EC1
Camargo, EE1
Ramos, CD1
Le Heuzey, JY1
De Ferrari, GM1
Radzik, D1
Santini, M1
Zhu, J1
Davy, JM1
Thomas, Z1
Bandali, F1
McCowen, K1
Malhotra, A1
Barbesino, G1
Lee, KF1
Lee, KM1
Fung, TT1
Tsadok, MA1
Jackevicius, CA1
Rahme, E1
Essebag, V1
Eisenberg, MJ1
Humphries, KH1
Tu, JV1
Behlouli, H1
Joo, J1
Pilote, L1
Kesselheim, AS1
Fatima, N1
Sajjad, Z1
Leung, AM1
Braverman, LE8
Biondi, B1
Martin, CM1
Nishikawa, M1
Toyoda, N1
Nomura, E1
Siccama, R1
Balk, AH1
de Herder, WW1
van Domburg, R1
Vantrimpont, P1
van Gelder, T1
Pearce, EN1
Bogazzi, F4
Brogioni, S2
Pardini, E1
Pellegrini, G1
Parkes, AB1
Lazarus, JH1
Pinchera, A3
Mel'nichenko, GA2
Sviridenko, NIu4
Molashenko, NV4
Platonova, NM4
Aleksandrova, GF1
Egorov, AV2
Perazza, L1
Scardi, S1
de Paola, AV1
Cirenza, C1
Maciel, RM1
Fuks, AG1
Vaisman, M1
Buescu, A1
Serdiuk, SE2
Bakalov, SA2
Soboleva, VA1
Golitsin, SP1
Zyśko, D1
Gajek, J1
Golitsyn, SP1
Dedov, II1
Schmidt-Ott, UM1
Ascheim, DD1
Kucharczyk, P1
Michałkiewicz, D1
Kucharczyk, A1
Kurnik, D1
Loebstein, R1
Olchovsky, D1
Goldschlager, N1
Epstein, AE1
Naccarelli, GV1
Olshansky, B1
Singh, B1
Collard, HR1
Murphy, E1
Batcher, EL1
Tang, XC1
Singh, BN2
Singh, SN1
Reda, DJ1
Hershman, JM2
Mikosch, P1
Blank, W1
Braun, B1
Borst, GC1
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Friocourt, P1
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Heger, JJ1
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Jonckheer, MH3
Larsen, PR2
Lambert, M1
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Ferrero, C1
Kulbertus, HE1
Demoulin, JC1
Bertholet, M1
Jaggarao, NS1
Sheldon, J1
Grundy, EN1
Vincent, R1
Chamberlain, DA1
Paulus, WJ1
Ranquin, R1
Parizel, G1
Ahmad, S1
Follin, SL1
Ordelova, A1
Webb, CR1
Shukla, R1
Jowett, NI1
Thompson, DR1
Pohl, JE1
Nyström, E1
Lindstedt, G1
Tisell, LE1
Berg, G1
Edvardsson, N1
Walfridsson, H1
Adlerberth, A1
Wemeau, JL3
Bauters, C1
Coviaux, R1
Anouilh, A1
Maillez, T1
D'herbomez, M1
Devemy, F1
Decoulx, M2
Schlienger, JL1
Kaltenbach, G1
Offner, M1
Sapin, R1
Gasser, G1
Roul, G1
Allain, P1
Berre, S1
Krari, N1
Lainé-Cessac, P1
Le Bouil, A1
Barbot, N1
Rohmer, V1
Bigorgne, JC1
Gittoes, NJ1
Franklyn, JA4
Wenzel, KW1
Leenhardt, L1
Banerjee, S1
James, CB1
Iervasi, G1
Clerico, A1
Bonini, R1
Manfredi, C1
Berti, S1
Ravani, M1
Palmieri, C1
Carpi, A1
Biagini, A1
Chopra, IJ1
Harjai, KJ1
Licata, AA1
Bartalena, L7
Manetti, L1
Wiersinga, WM3
Pitsiavas, V1
Smerdely, P1
Li, M1
Boyages, SC1
Lancellotti, P1
Mélon, P1
Kulbertus, H1
Modlinska, A1
Sworczak, K1
Loviselli, A2
Murenu, S1
Sau, F2
Valentino, L1
Mandas, A1
Vacquer, S1
Balestrieri, A2
Lai, ME1
Thorne, SA1
Barnes, I1
Cullinan, P1
Somerville, J1
Loh, KC1
Erdoğan, MF1
Güleç, S1
Tutar, E1
Güldal, M1
Başkal, N1
Erdoğan, G1
Roti, E1
Uberti, ED1
Markou, K1
Georgopoulos, N1
Kyriazopoulou, V1
Vagenakis, AG1
Gasperi, M1
Shiga, T1
Wakaumi, M1
Matsuda, N1
Shoda, M1
Hagiwara, N1
Kasanuki, H1
Jeantet, M1
Losay, J1
Cassinat, G1
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Machado, HB1
da Silva, ME1
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Gómez, JM1
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Gausi, C1
Soler, J1
Pathé, M1
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Widerhorn, J1
Bhandari, AK1
Bughi, S1
Rahimtoola, SH1
Elkayam, U1
Chow, CC1
Cockram, CS1
Briançon, C1
Halpern, S1
Telenczak, P1
Fragu, P2
De Rosa, G1
Corsello, SM1
Testa, A1
Callà, C1
Simonin, R1
Kennedy, RL1
Griffiths, H1
Gray, TA1
Málek, Z1
Dorociaková, E1
Kojsová, M1
Willems, AR1
Schöttelndreiër, MA1
Manouvrier, J1
Cappoen, JP1
Caron, C1
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Edan, G1
Massart, C1
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Le Helloco, A1
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Natoli, A1
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Galvão-teles, A1
Santos, ML1
Mourão, L1
Correia, MJ1
Lopo Tuna, J1
Ribeiro, C1
Endert, E1
Trip, MD2
Verhaest-de Jong, N1
Gammage, MD3
Balzano, S3
Raeder, EA1
Podrid, PJ1
Lown, B1
Pichler, WJ1
Schindler, L1
Stäubli, M1
Stadler, BM1
de Weck, AL1
Weetman, AP1
Bhandal, SK1
Burrin, JM1
Robinson, K1
McKenna, W1
Sica, V1
Pilosu, R1
Petrini, L1
Giannessi, G1
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Cherchi, A1
Rabinowe, SL1
Antman, EM1
George, KL1
Friedman, PL1
Jackson, RA1
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Schlumberger, M1
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Scolari, N1
Carini, L1
Lovagnini-Scher, CA1
Unger, J1

Clinical Trials (7)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hypothyroidism After the TAVI Procedure in Elderly Patients[NCT04831957]20 participants (Anticipated)Interventional2021-07-26Recruiting
First-line Cryoablation for Early Treatment of Persistent Atrial Fibrillation - a Randomized Study Comparing Early Trigger Isolation Using the Cryoballoon Versus Antiarrhythmic Medication[NCT05939076]Phase 3220 participants (Anticipated)Interventional2023-08-21Not yet recruiting
Randomized Double Blind Trial to Evaluate the Efficacy and Safety of Dronedarone (400mg BID) Versus Amiodarone (600mg Daily for 28 Days, Then 200mg Daily Thereafter) for at Least 6 Months for the Maintenance of Sinus Rhythm in Patients With Atrial Fibrill[NCT00489736]Phase 3504 participants (Actual)Interventional2007-06-30Completed
Pragmatic Randomized Clinical Trial of Early Dronedarone Versus Usual Care to Change and Improve Outcomes in Persons With First-Detected Atrial Fibrillation[NCT05130268]Phase 43,000 participants (Anticipated)Interventional2021-10-29Active, not recruiting
Efficacy of Metformin Versus Sitagliptin on Benign Thyroid Nodules Size in Type 2 Diabetes: a 2-years Prospective Multicentric Study[NCT04298684]Phase 490 participants (Anticipated)Interventional2021-01-01Not yet recruiting
Telemedicine Enabling Patients in Self-care Behaviors[NCT04297735]60 participants (Actual)Interventional2020-02-26Completed
aMsa and amiOdarone Study in cArdiaC Arrest[NCT04997980]500 participants (Anticipated)Observational2015-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Occurrence of the Main Safety Endpoint (MSE) Defined as Thyroid, Hepatic, Pulmonary, Neurological, Skin, Eye, or Gastrointestinal Specific Treatment Emergent Events or Premature Study Drug Discontinuation Following Any Adverse Event

"The considered event is the occurrence of the MSE defined as thyroid, hepatic, pulmonary, neurological, skin, eye, or gastrointestinal specific treatment emergent events or premature study drug discontinuation following any adverse event (AE), whichever comes first. The analysis is performed on the time from first study drug intake to this event. The Measured Values table below presents the numbers of patients with the event at the end of the study period." (NCT00489736)
Timeframe: minimum study duration is 6 months (+10 days); maximum is 15 months

Interventionparticipants (Number)
Dronedarone 400mg Bid83
Amiodarone 600mg/200mg od107

Occurrence of the MSE Excluding Gastrointestinal Specific Treatment Emergent Events Defined as Diarrhoea, Nausea, Vomiting

"The considered event is the occurrence of the MSE excluding gastrointestinal specific treatment emergent events defined as diarrhoea, nausea, vomiting. The analysis is performed on the time from first study drug intake to this event. The Measured Values table below presents the numbers of patients with the event at the end of the study period." (NCT00489736)
Timeframe: minimum study duration is 6 months (+10 days); maximum is 15 months

Interventionparticipants (Number)
Dronedarone 400mg Bid61
Amiodarone 600mg/200mg od99

Treatment Failure

"The primary event is the treatment failure defined as the first recurrence of atrial fibrillation or premature study drug discontinuation for intolerance or lack of efficacy according to the investigator judgement. The primary efficacy analysis is performed on the time from first study drug intake to this primary event. The Measured Values table below presents the numbers of patients with the event at the end of the study period." (NCT00489736)
Timeframe: minimum study duration is 6 months (+10 days); maximum is 15 months

Interventionparticipants (Number)
Dronedarone 400mg Bid184
Amiodarone 600mg/200mg od141

Reviews

52 reviews available for amiodarone and Thyroid Diseases

ArticleYear
Thyroid effects of amiodarone: clinical update.
    Current opinion in endocrinology, diabetes, and obesity, 2020, Volume: 27, Issue:5

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Child; Drug Monitoring; Humans; Incidence; Prevalence; Th

2020
Evaluation and Treatment of Amiodarone-Induced Thyroid Disorders.
    The Journal of clinical endocrinology and metabolism, 2021, 01-01, Volume: 106, Issue:1

    Topics: Albania; Amiodarone; Arrhythmias, Cardiac; Coronary Artery Disease; Humans; Male; Middle Aged; Myoca

2021
Amiodarone-Induced Thyroid Dysfunction: A Clinical Update.
    Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association, 2018, Volume: 126, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Chest Pain; Coronary Artery Disease; Humans; Male; Middle Aged;

2018
Amiodarone and thyroid physiology, pathophysiology, diagnosis and management.
    Trends in cardiovascular medicine, 2019, Volume: 29, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Humans; Predictive Value of Tests; Prognosis; Risk Asse

2019
Thyroid and Eye: Where They Meet in Clinical Practice.
    Endocrine, metabolic & immune disorders drug targets, 2020, Volume: 20, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antithyroid Agents; Diabetic Retinopathy; Eye; Eye Dise

2020
Thyroid Disease and the Heart.
    Current problems in cardiology, 2016, Volume: 41, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Heart Diseases; Hemodynamics; Humans; Hydroxymethylglut

2016
[Clinical procedure in amiodarone-induced thyroid dysfunction].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2016, Volume: 40, Issue:235

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Hypothyroidism; Risk Factors; Thyroid Diseases; Thyroid

2016
Benzofuran derivatives and the thyroid.
    Clinical endocrinology, 2009, Volume: 70, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzofurans; Dronedarone; Humans; Hypothyroidism; Recep

2009
Amiodarone-induced thyrotoxicosis. A review.
    Minerva endocrinologica, 2008, Volume: 33, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Interleukin-6; Iodine; Iodine Radioisotopes; Iopanoic Ac

2008
Recombinant human thyrotropin in the management of thyroid disorders.
    Expert opinion on biological therapy, 2008, Volume: 8, Issue:11

    Topics: Amiodarone; Clinical Trials as Topic; Goiter; Humans; Iodine Radioisotopes; Neoplasm Metastasis; Rec

2008
Effects of amiodarone therapy on thyroid function.
    Nature reviews. Endocrinology, 2010, Volume: 6, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Dronedarone; Humans; Hypothyroidism; Iodine; Thyroid Di

2010
Management of thyroid disorders in primary care: challenges and controversies.
    Postgraduate medical journal, 2009, Volume: 85, Issue:1010

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Primary Health Care; Thyroid Diseases; Triiodothyronine

2009
Drug-induced endocrine disorders in the intensive care unit.
    Critical care medicine, 2010, Volume: 38, Issue:6 Suppl

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antifungal Agents; Antimanic Agents; Critical Care; Cytochrome P

2010
Drugs affecting thyroid function.
    Thyroid : official journal of the American Thyroid Association, 2010, Volume: 20, Issue:7

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antipsychotic Agents; Drug Interactions; Drug Monitorin

2010
Amiodarone therapy: don't forget thyroid.
    JPMA. The Journal of the Pakistan Medical Association, 2012, Volume: 62, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Thyroid Diseases; Thyroid Hormones

2012
Iodine-induced thyroid dysfunction.
    Current opinion in endocrinology, diabetes, and obesity, 2012, Volume: 19, Issue:5

    Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Child; Child, Preschool; Dietary Supplements;

2012
Mechanisms in endocrinology: Heart failure and thyroid dysfunction.
    European journal of endocrinology, 2012, Volume: 167, Issue:5

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Disease;

2012
[Drug-induced thyroid dysfunction].
    Nihon rinsho. Japanese journal of clinical medicine, 2012, Volume: 70, Issue:11

    Topics: Amiodarone; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland; Thyroid Hormones

2012
Using oral amiodarone safely.
    Drug and therapeutics bulletin, 2003, Volume: 41, Issue:2

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Eruptions; Drug

2003
[Amiodarone-induced thyroid dysfunction (pathogenesis, diagnosis, treatment)].
    Terapevticheskii arkhiv, 2003, Volume: 75, Issue:8

    Topics: Amiodarone; Humans; Iodide Peroxidase; Receptors, Thyroid Hormone; Thyroid Diseases; Thyrotropin

2003
[Amiodarone and thyroid dysfunction: a pending problem].
    Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace, 2003, Volume: 60, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Hypothyroidism; Thyroid Diseases

2003
[Thyroid and cardiovascular disorders].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2004, Volume: 16, Issue:95

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiovascular Diseases; Coronary Artery B

2004
Thyroid hormone and heart failure.
    Current heart failure reports, 2006, Volume: 3, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Heart Failure; Humans; Thyroid Diseases; Thyroxine; Triiodothyro

2006
[Thyroid and treatment with amiodarone diagnosis, therapy and clinical management].
    Wiener medizinische Wochenschrift (1946), 2008, Volume: 158, Issue:1-2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Female; Follow-Up Studies; Humans; Hyperthyr

2008
Euthyroid hyperthyroxinemia.
    Annals of internal medicine, 1983, Volume: 98, Issue:3

    Topics: Amiodarone; Amphetamines; Blood Protein Disorders; Female; Humans; Ipodate; Male; Mental Disorders;

1983
[Side effects of amiodarone].
    Annales de medecine interne, 1983, Volume: 134, Issue:1

    Topics: Amiodarone; Benzofurans; Brain Diseases; Cardiovascular Diseases; Eye Diseases; Humans; Skin Disease

1983
Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:4

    Topics: Administration, Oral; Amiodarone; Animals; Arrhythmias, Cardiac; Atrioventricular Node; Benzofurans;

1984
Euthyroid hyperthyroxinemia.
    Journal of endocrinological investigation, 1983, Volume: 6, Issue:6

    Topics: Amiodarone; Autoantibodies; Dextroamphetamine; Heparin; Humans; Propranolol; Serum Albumin; Thyroglo

1983
Thyroid-pituitary interaction: feedback regulation of thyrotropin secretion by thyroid hormones.
    The New England journal of medicine, 1982, Jan-07, Volume: 306, Issue:1

    Topics: Adolescent; Amiodarone; Animals; Brain; Cholecystography; Feedback; Female; Graves Disease; Humans;

1982
Drug-induced thyroid disorders.
    Drug safety, 1995, Volume: 13, Issue:1

    Topics: Amiodarone; Drug-Related Side Effects and Adverse Reactions; Humans; Iodine; Lithium; Thyroid Diseas

1995
Disturbances of thyroid function tests by drugs.
    Acta medica Austriaca, 1996, Volume: 23, Issue:1-2

    Topics: Amiodarone; Diagnosis, Differential; Drug-Related Side Effects and Adverse Reactions; Humans; Predic

1996
Amiodarone-induced dysthyroidism. Pitfalls and management.
    Le Journal medical libanais. The Lebanese medical journal, 1995, Volume: 43, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Monitoring; Female; Humans; Male; Thyroid Diseases; Thyroid

1995
Effects of amiodarone on thyroid function.
    Annals of internal medicine, 1997, Jan-01, Volume: 126, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Heart; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid

1997
[Follow-up of patients treated by amiodarone].
    Revue medicale de Liege, 1998, Volume: 53, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Contraindications; Drug Interactions; Drug Monitoring; Follow-Up

1998
[Amiodarone and the thyroid gland].
    Polskie Archiwum Medycyny Wewnetrznej, 1998, Volume: 100, Issue:1

    Topics: Amiodarone; Animals; Dose-Response Relationship, Drug; Humans; Thyroid Diseases; Thyroid Gland; Thyr

1998
Amiodarone-induced thyroid disorders: a clinical review.
    Postgraduate medical journal, 2000, Volume: 76, Issue:893

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Thyroid Diseases

2000
HLA-B40-, HLA-Cw3-, and HLA-DR5-associated susceptibility to amiodarone-induced thyroid dysfunction.
    Thyroid : official journal of the American Thyroid Association, 2000, Volume: 10, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; HLA Antigens; HLA-B Antigens; HLA-B40 Antigen; HLA-C Antigens; H

2000
The effects of amiodarone on the thyroid.
    Endocrine reviews, 2001, Volume: 22, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Female; Hormone Replacement Therapy; Humans;

2001
Iodine excess and hyperthyroidism.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Amiodarone; Endemic Diseases; Environmental Exposure; Goiter; Graves Disease; Hyperthyroidism; Iodin

2001
Iodine-Induced hypothyroidism.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Amiodarone; Drug Synergism; Female; Goiter; Humans; Hypothyroidism; Infant, Newborn; Iodides; Iodine

2001
The various effects of amiodarone on thyroid function.
    Thyroid : official journal of the American Thyroid Association, 2001, Volume: 11, Issue:5

    Topics: Amiodarone; Female; Humans; Hypothyroidism; Male; Pregnancy; Thyroid Diseases; Thyroid Gland; Thyrot

2001
Iodine effects on the thyroid gland: biochemical and clinical aspects.
    Reviews in endocrine & metabolic disorders, 2000, Volume: 1, Issue:1-2

    Topics: Amiodarone; Autoimmune Diseases; Contrast Media; Humans; Hyperthyroidism; Iodides; Iodine; Iodine Ra

2000
[Does amiodarone have a benefit effect on mortality?].
    Presse medicale (Paris, France : 1983), 1991, Sep-14, Volume: 20, Issue:28

    Topics: Amiodarone; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Eye Diseases; France; Heart Arrest; Humans

1991
Fetal and neonatal adverse effects profile of amiodarone treatment during pregnancy.
    American heart journal, 1991, Volume: 122, Issue:4 Pt 1

    Topics: Adult; Amiodarone; Female; Fetal Diseases; Humans; Infant, Newborn; Infant, Newborn, Diseases; Infan

1991
Thyroid disorders induced by lithium and amiodarone: an overview.
    Adverse drug reactions and acute poisoning reviews, 1990,Winter, Volume: 9, Issue:4

    Topics: Amiodarone; Animals; Goiter; Humans; Hypothyroidism; Lithium; Thyroid Diseases; Thyroid Hormones; Th

1990
[Amiodarone-induced thyroid pathology].
    La Clinica terapeutica, 1987, Dec-31, Volume: 123, Issue:6

    Topics: Amiodarone; Antithyroid Agents; Female; Humans; Hyperthyroidism; Hypothyroidism; Lithium; Male; Midd

1987
Amiodarone and the thyroid.
    Clinical chemistry, 1989, Volume: 35, Issue:9

    Topics: Amiodarone; Disease Susceptibility; Humans; Thyroid Diseases; Thyroid Hormones

1989
[Amiodarone and its side effects].
    Nederlands tijdschrift voor geneeskunde, 1988, Mar-26, Volume: 132, Issue:13

    Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Corneal Diseases; Humans; Lung Diseases; Periphe

1988
Amiodarone and the thyroid.
    The Quarterly journal of medicine, 1987, Volume: 62, Issue:238

    Topics: Amiodarone; Heart; Heart Diseases; Humans; Thyroid Diseases; Thyroid Gland; Thyroid Hormones

1987
[Amiodarone, a class 3 antiarrhythmic agent: current electrophysiological and therapeutic aspects].
    Revue medicale de Bruxelles, 1986, Volume: 7, Issue:2

    Topics: Administration, Oral; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cardiomyopathy, Hypertrophic; H

1986
[Thyroid function and amiodarone. Consequences on dysthyroidism testing].
    Annales de cardiologie et d'angeiologie, 1985, Volume: 34, Issue:1

    Topics: Amiodarone; Animals; Benzofurans; Biotransformation; Humans; Hyperthyroidism; Hypothyroidism; Iodine

1985
[Amiodarone: pharmacology, clinical use and side effects].
    Vutreshni bolesti, 1985, Volume: 24, Issue:5

    Topics: Amiodarone; Arrhythmias, Cardiac; Autonomic Nervous System; Benzofurans; Blood Coagulation; Digitali

1985

Trials

7 trials available for amiodarone and Thyroid Diseases

ArticleYear
Thyroid function in heart failure and impact on mortality.
    JACC. Heart failure, 2013, Volume: 1, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Female; Heart Failure; Humans

2013
Short-term amiodarone treatment for atrial fibrillation after catheter ablation induces a transient thyroid dysfunction: Results from the placebo-controlled, randomized AMIO-CAT trial.
    European journal of internal medicine, 2016, Volume: 33

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Denmark; Double-Bl

2016
Tc-99m sestamibi thyroid imaging in patients on chronic amiodarone treatment: a comparison with Tc-99m pertechnetate imaging.
    Clinical nuclear medicine, 2010, Volume: 35, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chronic Disease; Female; Humans;

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
A short-term, randomized, double-blind, parallel-group study to evaluate the efficacy and safety of dronedarone versus amiodarone in patients with persistent atrial fibrillation: the DIONYSOS study.
    Journal of cardiovascular electrophysiology, 2010, Jun-01, Volume: 21, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Double-Blind Method; Dronedarone; Ele

2010
Thyroid function abnormalities during amiodarone therapy for persistent atrial fibrillation.
    The American journal of medicine, 2007, Volume: 120, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cohort Studies; Female; Humans; Hyper

2007
Antithyroid antibodies as an early marker for thyroid disease induced by amiodarone.
    British medical journal (Clinical research ed.), 1986, Jan-25, Volume: 292, Issue:6515

    Topics: Adult; Aged; Amiodarone; Antibody Formation; Autoantibodies; Autoimmune Diseases; Benzofurans; Doubl

1986
[Extracardiac side effects of Aminodarone].
    Giornale italiano di cardiologia, 1986, Volume: 16, Issue:2

    Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Clinical Trials as Topic; Drug Evaluation; Eye Diseas

1986

Other Studies

97 other studies available for amiodarone and Thyroid Diseases

ArticleYear
[Thyroid ultrasound and its role in the investigation of thyroid disease].
    Lakartidningen, 2022, 10-25, Volume: 119

    Topics: Amiodarone; Female; Graves Disease; Humans; Thyroid Diseases; Thyrotoxicosis

2022
Incidence of thyroid dysfunction following initiation of amiodarone treatment in patients with and without heart failure: a nationwide cohort study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023, 02-16, Volume: 25, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Heart Failure; Humans; Hypothyroidism; Incidence

2023
Incidence of thyroid dysfunction following initiation of amiodarone treatment in patients with and without heart failure: a nationwide cohort study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023, 02-16, Volume: 25, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Heart Failure; Humans; Hypothyroidism; Incidence

2023
Incidence of thyroid dysfunction following initiation of amiodarone treatment in patients with and without heart failure: a nationwide cohort study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023, 02-16, Volume: 25, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Heart Failure; Humans; Hypothyroidism; Incidence

2023
Incidence of thyroid dysfunction following initiation of amiodarone treatment in patients with and without heart failure: a nationwide cohort study.
    Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology, 2023, 02-16, Volume: 25, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Heart Failure; Humans; Hypothyroidism; Incidence

2023
[HEPATOCELLULAR TOXICITY IN THE BACKGROUND OF AMIODARON-INDUCED THYROID DYSFUNCTION IN PATIENTS WITH ATRIAL FIBRILLATION].
    Georgian medical news, 2019, Issue:297

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Hum

2019
Letter to the Editor from Sukor et al: "Evaluation and Treatment of Amiodarone-Induced Thyroid Disorders".
    The Journal of clinical endocrinology and metabolism, 2021, 05-13, Volume: 106, Issue:6

    Topics: Amiodarone; Humans; Thyroid Diseases

2021
Response to Letter to the Editor from Sukor et al.: "Evaluation and Treatment of Amiodarone-induced Thyroid Disorders".
    The Journal of clinical endocrinology and metabolism, 2021, 06-16, Volume: 106, Issue:7

    Topics: Amiodarone; Humans; Thyroid Diseases

2021
Editorial commentary: Amiodarone-induced thyroid diseases: Additional unintended consequences.
    Trends in cardiovascular medicine, 2019, Volume: 29, Issue:5

    Topics: Amiodarone; Humans; Thyroid Diseases

2019
The Effects of Amiodarone on Thyroid Function in Pediatric and Young Adult Patients.
    The Journal of clinical endocrinology and metabolism, 2019, 11-01, Volume: 104, Issue:11

    Topics: Adolescent; Amiodarone; Arrhythmias, Cardiac; Child; Child, Preschool; Female; Humans; Incidence; In

2019
[Editor's commentary. Advances in endocrinology].
    Orvosi hetilap, 2013, Dec-22, Volume: 154, Issue:51

    Topics: Amiodarone; Anti-Arrhythmia Agents; Diabetic Neuropathies; Endocrine System Diseases; Female; Humans

2013
Using fractional polynomials to model the effect of cumulative duration of exposure on outcomes: applications to cohort and nested case-control designs.
    Pharmacoepidemiology and drug safety, 2014, Volume: 23, Issue:8

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Case-Control Studies; Cohort Studies; Diphosphonates; Epid

2014
Adherence to guidelines in monitoring amiodarone-induced thyroid dysfunction.
    Journal of evaluation in clinical practice, 2017, Volume: 23, Issue:1

    Topics: Age Factors; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Guideline Adherenc

2017
Population-level incidence and monitoring of adverse drug reactions with long-term amiodarone therapy.
    Cardiovascular therapeutics, 2017, Volume: 35, Issue:3

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury;

2017
A survey of thyroid function test abnormalities in patients presenting with atrial fibrillation and flutter to a New Zealand district hospital.
    The New Zealand medical journal, 2008, Nov-07, Volume: 121, Issue:1285

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flut

2008
Association of polymorphism at position 49 in exon 1 of the cytotoxic T-lymphocyte-associated factor 4 gene with Graves' disease refractory to medical treatment, but not with amiodarone-associated thyroid dysfunction.
    Thyroid : official journal of the American Thyroid Association, 2009, Volume: 19, Issue:9

    Topics: Adult; Amiodarone; Antigens, CD; CTLA-4 Antigen; Female; Graves Disease; Humans; Male; Middle Aged;

2009
Amiodarone-induced thyroid dysfunction in the Hong Kong Chinese population.
    Hong Kong medical journal = Xianggang yi xue za zhi, 2010, Volume: 16, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; China; Female; Humans; Hypothyro

2010
Amiodarone-induced thyroid dysfunction: brand-name versus generic formulations.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Sep-06, Volume: 183, Issue:12

    Topics: Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chi-Square Distribution;

2011
The backlash against bioequivalence and the interchangeability of brand-name and generic drugs.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 2011, Sep-06, Volume: 183, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drugs, Generic; Female; Humans; Male; Thyro

2011
Thyroid dysfunction and the elderly patient: a primer for pharmacists.
    The Consultant pharmacist : the journal of the American Society of Consultant Pharmacists, 2012, Volume: 27, Issue:10

    Topics: Aged; Amiodarone; Humans; Hyperthyroidism; Hypothyroidism; Pharmacists; Thyroid Diseases; Thyroid Gl

2012
Amiodarone therapy before heart transplantation as a predictor of thyroid dysfunction after transplantation.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 2003, Volume: 22, Issue:8

    Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Child; Cohort Studies; Female; Heart Transpla

2003
The prevalence of elevated serum C-reactive protein levels in inflammatory and noninflammatory thyroid disease.
    Thyroid : official journal of the American Thyroid Association, 2003, Volume: 13, Issue:7

    Topics: Adolescent; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; C-Reactive Protein; Case-Control Studie

2003
[The cardiologist should suspect more thyroid dysfunction!].
    Arquivos brasileiros de cardiologia, 2004, Volume: 82, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Heart Diseases; Humans; Male; Risk Factors; Thyroid Dise

2004
Thyroid dysfunction and cardiological management in patients receiving amiodarone.
    Arquivos brasileiros de cardiologia, 2004, Volume: 82, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Brazil; Female; Heart Diseases; Humans; Male; Middle Aged; Preva

2004
[Amiodarone-associated thyroid dysfunction: prevalence and possibilities of correction].
    Kardiologiia, 2004, Volume: 44, Issue:10

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Antithyroid Agents; Data Interpretatio

2004
[Incidence and predictors of thyroid dysfunction caused by long-term intake of amiodaron].
    Terapevticheskii arkhiv, 2005, Volume: 77, Issue:10

    Topics: Age Factors; Amiodarone; Anti-Arrhythmia Agents; Female; Heart Failure; Humans; Hypothyroidism; Inci

2005
[Diagnostics, treatment, and prevention of iatrogenic iodine-induced thyroid gland diseases].
    Vestnik Rossiiskoi akademii meditsinskikh nauk, 2006, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Follow-Up Studies; Humans; Iatroge

2006
[The effects of amiodaron on the thyroid function].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:121

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Thyroid Disease

2006
Amiodarone for atrial fibrillation.
    The New England journal of medicine, 2007, Jun-07, Volume: 356, Issue:23

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Humans; International Norma

2007
A practical guide for clinicians who treat patients with amiodarone: 2007.
    Heart rhythm, 2007, Volume: 4, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Female; Humans; Lung Diseases; Male; Tachycar

2007
[Sonography of the thyroid--part 2: thyroid inflammation, impairmant of thyroid function and interventions].
    Ultraschall in der Medizin (Stuttgart, Germany : 1980), 2008, Volume: 29, Issue:2

    Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Chronic Disease; Female; Humans; Hyperthyroidism;

2008
Amiodarone: its side effects, adverse reactions and dosage schedules.
    The New Zealand medical journal, 1982, Jul-28, Volume: 95, Issue:712

    Topics: Amiodarone; Benzofurans; Central Nervous System Diseases; Drug Administration Schedule; Eye Diseases

1982
Side effects of long-term amiodarone therapy.
    Circulation, 1983, Volume: 67, Issue:1

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Corneal Diseases; Dose-Response Relation

1983
[The classic anti-anginal agents and molsidomine].
    Archives des maladies du coeur et des vaisseaux, 1983, Volume: 76 Spec No

    Topics: Amiodarone; Angina Pectoris; Angina Pectoris, Variant; Humans; Kinetics; Molsidomine; Oxadiazoles; P

1983
Effect of amiodarone on thyroid hormone economy.
    Israel journal of medical sciences, 1984, Volume: 20, Issue:2

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Hyperthyroidism; Hypothy

1984
Environmental iodine intake and thyroid dysfunction during chronic amiodarone therapy.
    Annals of internal medicine, 1984, Volume: 101, Issue:1

    Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Goiter; Heart Diseases; Humans; Hyperthyroidism; Hypot

1984
Side effects during therapy with low dosage amiodarone.
    Giornale italiano di cardiologia, 1984, Volume: 14, Issue:9

    Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Female; Humans; Male;

1984
Goitre and thyroid dysfunction during chronic amiodarone treatment.
    The New Zealand medical journal, 1984, Apr-11, Volume: 97, Issue:753

    Topics: Adult; Amiodarone; Benzofurans; Female; Goiter; Humans; Male; Thyroid Diseases; Thyroid Function Tes

1984
Long-term efficacy and toxicity of high-dose amiodarone therapy for ventricular tachycardia or ventricular fibrillation.
    The American journal of cardiology, 1983, Nov-01, Volume: 52, Issue:8

    Topics: Aged; Amiodarone; Anorexia; Ataxia; Benzofurans; Female; Heart Arrest; Humans; Lung Diseases; Male;

1983
[Amiodarone in the treatment of cardiac rhythm disturbances in children. Apropos of 135 cases].
    Archives des maladies du coeur et des vaisseaux, 1980, Volume: 73, Issue:2

    Topics: Administration, Oral; Adolescent; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Child, Presc

1980
Amiodarone and the thyroid gland. A review.
    Acta cardiologica, 1981, Volume: 36, Issue:3

    Topics: Amiodarone; Animals; Benzofurans; Dogs; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Thyroid Dis

1981
[Modifications and surveillance of thyroid tests during treatment with amiodarone].
    Therapeutische Umschau. Revue therapeutique, 1982, Volume: 39, Issue:2

    Topics: Amiodarone; Benzofurans; Humans; Thyroid Diseases; Thyroid Function Tests

1982
[Amiodarone: review of its antianginal properties and analysis of side effects].
    Herz, 1982, Volume: 7, Issue:5

    Topics: Amiodarone; Angina Pectoris; Arrhythmias, Cardiac; Benzofurans; Corneal Diseases; Coronary Vessels;

1982
The effects of amiodarone on thyroid function.
    Postgraduate medical journal, 1982, Volume: 58, Issue:685

    Topics: Adult; Aged; Amiodarone; Benzofurans; Humans; Middle Aged; Thyroid Diseases; Thyroid Gland; Thyroxin

1982
Systolic time intervals: a valuable parameter of thyroid function.
    Angiology, 1980, Volume: 31, Issue:2

    Topics: Adult; Amiodarone; Female; Humans; Hyperthyroidism; Male; Myocardial Contraction; Systole; Thyroid D

1980
Treatment guidelines for hyperthyroidism and hypothyroidism.
    JAMA, 1995, Oct-04, Volume: 274, Issue:13

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Practice Guidelines as Topic; Thyro

1995
Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone.
    Journal of clinical pharmacology, 1995, Volume: 35, Issue:4

    Topics: Adult; Age Factors; Aged; Amiodarone; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury;

1995
Side effects with amiodarone therapy.
    Postgraduate medical journal, 1994, Volume: 70, Issue:825

    Topics: Aged; Amiodarone; Drug Administration Schedule; Drug Eruptions; Female; Humans; Male; Middle Aged; N

1994
[Amiodarone--a warning! Clarify possible thyroid disease before treatment!].
    Lakartidningen, 1994, Sep-28, Volume: 91, Issue:39

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Thyroid Diseases; Thyroid Function Tests; Thyroid Gland

1994
[Thyroid dysfunctions related to amiodarone. Prospective survey with 116 patients].
    La Revue de medecine interne, 1993, Volume: 14, Issue:10

    Topics: Aged; Aged, 80 and over; Amiodarone; Female; Humans; Male; Middle Aged; Prospective Studies; Thyroid

1993
[Increase of free fatty acids under the effect of amiodarone].
    Presse medicale (Paris, France : 1983), 1994, Mar-19, Volume: 23, Issue:11

    Topics: Amiodarone; Fatty Acids, Nonesterified; Humans; Reference Values; Thyroid Diseases; Thyroid Hormones

1994
Use of plasma iodine assay for diagnosing thyroid disorders.
    Journal of clinical pathology, 1993, Volume: 46, Issue:5

    Topics: Adult; Aged; Amiodarone; Female; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Ma

1993
Amiodarone and dysthyroid eye disease.
    The British journal of ophthalmology, 1996, Volume: 80, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Eye Diseases; Humans; Male; Thyroid Diseases

1996
Acute effects of amiodarone administration on thyroid function in patients with cardiac arrhythmia.
    The Journal of clinical endocrinology and metabolism, 1997, Volume: 82, Issue:1

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Kinetics; Male; Middle Aged; Thyroid Disease

1997
[Amiodarone and the thyroid].
    Cardiologia (Rome, Italy), 1995, Volume: 40, Issue:12 Suppl 1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Hypothyroidism; Thyroid Diseases; Thyroid Gland; Thyroto

1995
Towards an animal model of amiodarone-induced thyroid dysfunction.
    European journal of endocrinology, 1997, Volume: 137, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Thyroid Diseases; Thyroid Gland

1997
Amiodarone induces a different pattern of ultrastructural change in the thyroid to iodine excess alone in both the BB/W rat and the Wistar rat.
    European journal of endocrinology, 1997, Volume: 137, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Cell Nucleus; Endoplasmic Reticulum; Inclusi

1997
High prevalence of thyroid dysfunction in adult patients with beta-thalassemia major submitted to amiodarone treatment.
    Journal of endocrinological investigation, 1999, Volume: 22, Issue:1

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; beta-Thalassemia; Female; Humans; Hypothyroidism; Male; T

1999
Amiodarone-associated thyroid dysfunction: risk factors in adults with congenital heart disease.
    Circulation, 1999, Jul-13, Volume: 100, Issue:2

    Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Case-Control Studies; Female; Heart Defects,

1999
[Iatrogenic thyroid disorders].
    La Revue de medecine interne, 1999, Volume: 20 Suppl 1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antipsychotic Agents; Antiviral Agents; Humans; Iatrogenic Disea

1999
Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan.
    Japanese circulation journal, 2001, Volume: 65, Issue:11

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Drug Evaluation; Female; Follow-Up Studies; Humans; H

2001
[Paroxysmal atrial fibrillation in community medicine: management intentions and cost estimates].
    Archives des maladies du coeur et des vaisseaux, 2001, Volume: 94, Issue:10

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiovascular Dis

2001
[Iatrogenic thyroid pathology].
    La semaine des hopitaux : organe fonde par l'Association d'enseignement medical des hopitaux de Paris, 1977, Jun-23, Volume: 53, Issue:24

    Topics: Amiodarone; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Thyroid Diseases

1977
'Low T3 syndrome' in patients chronically treated with an iodine-containing drug, amiodarone.
    Clinical endocrinology, 1978, Volume: 9, Issue:1

    Topics: Amiodarone; Benzofurans; Humans; Iodine; Thyroid Diseases; Thyroxine; Triiodothyronine

1978
[Amiodarone and thyroid function].
    Archives des maladies du coeur et des vaisseaux, 1976, Volume: 69, Issue:12

    Topics: Amiodarone; Benzofurans; Coronary Disease; Thyroid Diseases

1976
[Thyroid function in patients during long-term treatment with amiodarone].
    Endokrynologia Polska, 1992, Volume: 43, Issue:1

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Thyroid Diseases;

1992
Long-term amiodarone therapy and antithyroid antibodies.
    The American journal of cardiology, 1992, Apr-01, Volume: 69, Issue:9

    Topics: Adult; Amiodarone; Autoantibodies; Female; Fluorescent Antibody Technique; Humans; Male; Middle Aged

1992
[Thyroid dysfunction induced by amiodarone in Catalonia. Prevalence and characteristics].
    Revista clinica espanola, 1991, Volume: 188, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Child; Female; Humans; Male; Middle Aged; Pr

1991
Changes in 127I mice thyroid follicle studied by analytical ion microscopy: a key for the comprehension of amiodarone-induced thyroid diseases.
    Endocrinology, 1990, Volume: 127, Issue:3

    Topics: Amiodarone; Animals; Cytoplasm; Diet; Female; Image Processing, Computer-Assisted; Iodine; Mice; Mic

1990
Iodine induced thyroid disease.
    Acta medica Austriaca, 1990, Volume: 17 Suppl 1

    Topics: Amiodarone; Female; Graves Disease; Humans; Hyperthyroidism; Hypothyroidism; Infant, Newborn; Iodine

1990
[Dysthyroidism caused by amiodarone. Frequency and diagnosis].
    Archives des maladies du coeur et des vaisseaux, 1989, Volume: 82, Issue:10

    Topics: Amiodarone; Humans; Hyperthyroidism; Hypothyroidism; Thyroid Diseases; Thyrotropin; Thyroxine; Triio

1989
[The effect of amiodarone on thyroid gland activity].
    Vnitrni lekarstvi, 1989, Volume: 35, Issue:7

    Topics: Adult; Aged; Amiodarone; Female; Humans; Male; Middle Aged; Thyroid Diseases; Thyroid Gland

1989
[Thyroid dis pre-existing or caused by amiodarone. A plea for a systematic hormone detection].
    Presse medicale (Paris, France : 1983), 1986, Sep-20, Volume: 15, Issue:30

    Topics: Amiodarone; Diagnosis, Differential; Humans; Thyroid Diseases; Thyrotropin

1986
[Prevalence of dysthyroidism during treatment with amiodarone].
    Presse medicale (Paris, France : 1983), 1988, Jan-23, Volume: 17, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Female; Humans; Male; Middle Aged; Thyroid Diseases

1988
[Adverse effects during chronic treatment with low-dose amiodarone].
    La Clinica terapeutica, 1985, Jul-15, Volume: 114, Issue:1

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Drug Interactions; Eye Diseases;

1985
Immunoradiometric assay of thyrotropin in plasma: its value in predicting response to thyroliberin stimulation and assessing thyroid function in amiodarone-treated patients.
    Clinical chemistry, 1986, Volume: 32, Issue:3

    Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Humans; Hyperthyroidism; Hypothyroidism; Immunoassay;

1986
Amiodarone and the thyroid.
    British journal of clinical practice. Supplement, 1986, Volume: 44

    Topics: Amiodarone; Benzofurans; Humans; Thyroid Diseases; Thyroid Gland; Thyroid Hormones

1986
Effect of amiodarone on circulating antithyroid antibodies.
    BMJ (Clinical research ed.), 1988, Aug-13, Volume: 297, Issue:6646

    Topics: Amiodarone; Autoantibodies; Female; Humans; Male; Thyroid Diseases; Thyroid Gland

1988
Side effects and complications of amiodarone therapy.
    American heart journal, 1985, Volume: 109, Issue:5 Pt 1

    Topics: Amiodarone; Arrhythmias, Cardiac; Ataxia; Benzofurans; Drug Eruptions; Drug Interactions; Female; Ga

1985
Anti-amiodarone antibodies: detection and relationship to the development of side effects.
    The American journal of medicine, 1988, Volume: 85, Issue:2

    Topics: Adult; Aged; Amiodarone; Antibodies; Arrhythmias, Cardiac; Female; Humans; Immunoassay; Male; Middle

1988
Amiodarone and thyroid autoimmunity in the United Kingdom.
    BMJ (Clinical research ed.), 1988, Jul-02, Volume: 297, Issue:6640

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Autoantibodies; Female; Humans; Male; Middle Aged; Prosp

1988
Absence of serum thyroid hormone autoantibodies in patients chronically treated with amiodarone.
    Journal of endocrinological investigation, 1988, Volume: 11, Issue:4

    Topics: Amiodarone; Autoantibodies; Female; Humans; Male; Thyroid Diseases; Thyroid Gland; Thyroid Hormones;

1988
Diagnosis of amiodarone-iodine-induced thyrotoxicosis(AIIT) associated with severe nonthyroidal illness.
    Journal of endocrinological investigation, 1987, Volume: 10, Issue:6

    Topics: Aged; Amiodarone; Diagnosis, Differential; Humans; Hyperthyroidism; Iodine; Male; Sex Hormone-Bindin

1987
Amiodarone therapy and autoimmune thyroid disease. Increase in a new monoclonal antibody-defined T cell subset.
    The American journal of medicine, 1986, Volume: 81, Issue:1

    Topics: Adult; Aged; Amiodarone; Antibodies, Monoclonal; Autoantibodies; Autoimmune Diseases; Benzofurans; F

1986
Effects of amiodarone during pregnancy.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1987, May-01, Volume: 136, Issue:9

    Topics: Adult; Amiodarone; Female; Heart Ventricles; Humans; Infant, Newborn; Iodine; Maternal-Fetal Exchang

1987
Risk factors for development of amiodarone-induced thyroid dysfunction.
    Journal of the American College of Cardiology, 1987, Volume: 10, Issue:3

    Topics: Amiodarone; Humans; Risk; Thyroid Diseases

1987
Amiodarone iodine-induced hypothyroidism: risk factors and follow-up in 28 cases.
    Clinical endocrinology, 1987, Volume: 26, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Autoantibodies; Female; Follow-Up Studies; Humans; Hypot

1987
Effects of amiodarone and thyroid dysfunction on myocardial calcium, serum calcium and thyroid hormones in the rat.
    British journal of pharmacology, 1987, Volume: 92, Issue:2

    Topics: Amiodarone; Animals; Calcium; Hypothyroidism; In Vitro Techniques; Male; Muscle Proteins; Myocardium

1987
Amiodarone and thyroid hormone metabolism.
    Postgraduate medical journal, 1986, Volume: 62, Issue:732

    Topics: Amiodarone; Angina Pectoris; Female; Humans; Hypothyroidism; Iodine; Male; Thyroid Diseases; Thyroid

1986
Amiodarone, thyroid hormone indexes, and altered thyroid function: long-term serial effects in patients with cardiac arrhythmias.
    The American journal of cardiology, 1986, Nov-01, Volume: 58, Issue:10

    Topics: Amiodarone; Arrhythmias, Cardiac; Female; Humans; Male; Middle Aged; Thyroid Diseases; Thyroid Funct

1986
[Thyroid, amiodarone and autoimmunity].
    Revista clinica espanola, 1986, Volume: 179, Issue:5

    Topics: Amiodarone; Autoantibodies; Humans; Middle Aged; Thyroid Diseases

1986
[Hyper and hypothyroidism induced by amiodarone].
    Medicina, 1986, Volume: 46, Issue:1

    Topics: Adult; Amiodarone; Female; Humans; Hyperthyroidism; Hypothyroidism; Imidazoles; Male; Middle Aged; P

1986
Amiodarone-induced thyroid gland dysfunction.
    The American journal of cardiology, 1987, Apr-01, Volume: 59, Issue:8

    Topics: Amiodarone; Female; Humans; Hypothyroidism; Iodine; Male; Tachycardia; Thyroid Diseases; Thyroid Gla

1987
[Incidence of thyroid dysfunction in patients during chronic treatment with amiodarone].
    Revista medica de Chile, 1985, Volume: 113, Issue:11

    Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Humans; Male; Middle Aged; Thyroid Diseases; Thyroid F

1985
[Recent advances in thyroid pathology in Chile].
    Revista medica de Chile, 1985, Volume: 113, Issue:6

    Topics: Adult; Amiodarone; Chile; Female; Humans; Iodine; Iodine Radioisotopes; Male; Middle Aged; Thyroid D

1985
Amiodarone and the thyroid.
    Annals of internal medicine, 1985, Volume: 102, Issue:3

    Topics: Amiodarone; Benzofurans; Humans; Thyroid Diseases; Thyroid Hormones

1985
[Amiodarone and the thyroid].
    Medicina clinica, 1985, Mar-16, Volume: 84, Issue:10

    Topics: Amiodarone; Benzofurans; Humans; Iodine; Thyroid Diseases; Thyroid Gland; Thyroid Hormones; Triiodot

1985
Amiodarone and antithyroid antibodies.
    Annals of internal medicine, 1985, Volume: 103, Issue:1

    Topics: Amiodarone; Autoantibodies; Benzofurans; Humans; Retrospective Studies; Thyroid Diseases; Thyroid Gl

1985
[Thyroid pathology iatrogenically induced by iodinated products].
    Revue medicale de Bruxelles, 1985, Volume: 6, Issue:6

    Topics: Amiodarone; Goiter; Humans; Hyperthyroidism; Hypothyroidism; Iodine; Thyroid Diseases; Thyroid Hormo

1985
[Hyper- or hypothyroidism in chronic treatment with amiodarone: a diagnostic and therapeutic dilemma].
    Revista medica de Chile, 1985, Volume: 113, Issue:5

    Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Humans; Hyperthyroidism; Hypothyroidism; Male; Middle

1985