amiodarone has been researched along with Stevens-Johnson Syndrome in 4 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 77-year-old female patient with symptomatic atrial fibrillation with fast ventricular rate despite conventional antiarrhythmic therapy was treated with dronedarone." | 3.81 | Toxic Epidermal Necrolysis During Dronedarone Treatment: First Report of a Severe Serious Adverse Event Of A New Antiarrhythmic Drug. ( Figulla, HR; Franz, M; Gecks, T; Jung, C; Kühnert, H; Prochnau, D; Schliemann, S, 2015) |
| "Two cases of toxic epidermal necrolysis (TEN) are presented." | 1.31 | Two unusual cases of toxic epidermal necrolysis. ( Agnew, K; Oliver, F; Snow, J; Yung, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, A | 1 |
| Sauer, W | 1 |
| Nguyen, DT | 1 |
| Gecks, T | 1 |
| Prochnau, D | 1 |
| Franz, M | 1 |
| Jung, C | 1 |
| Kühnert, H | 1 |
| Schliemann, S | 1 |
| Figulla, HR | 1 |
| Yung, A | 1 |
| Agnew, K | 1 |
| Snow, J | 1 |
| Oliver, F | 1 |
| Bencini, PL | 1 |
| Crosti, C | 1 |
| Sala, F | 1 |
| Bertani, E | 1 |
| Nobili, M | 1 |
4 other studies available for amiodarone and Stevens-Johnson Syndrome
| Article | Year |
|---|---|
A dire reaction: rash after amiodarone administration.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Exanthema; Female; Humans; Skin; Stev | 2013 |
Toxic Epidermal Necrolysis During Dronedarone Treatment: First Report of a Severe Serious Adverse Event Of A New Antiarrhythmic Drug.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biopsy; Dronedarone; Fatal Outcome; F | 2015 |
Two unusual cases of toxic epidermal necrolysis.
Topics: Adult; Aged; Amiodarone; Biopsy, Needle; Cyclosporins; Dextroamphetamine; Ephedrine; Fatal Outcome; | 2002 |
Toxic epidermal necrolysis and amiodarone treatment.
Topics: Aged; Amiodarone; Atrial Fibrillation; Benzofurans; Humans; Male; Stevens-Johnson Syndrome | 1985 |