amiodarone has been researched along with Primary Graft Dysfunction in 3 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Primary Graft Dysfunction: A form of ischemia-reperfusion injury occurring in the early period following transplantation. Significant pathophysiological changes in MITOCHONDRIA are the main cause of the dysfunction. It is most often seen in the transplanted lung, liver, or kidney and can lead to GRAFT REJECTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Recent studies have shown an increased incidence of primary graft dysfunction (PGD) in patients treated with amiodarone prior to orthotopic heart transplant (OHT)." | 7.96 | Discontinuing amiodarone treatment prior to heart transplantation lowers incidence of severe primary graft dysfunction. ( Ando, M; Colombo, P; Farr, M; Han, J; Hoemann, B; Jennings, DL; Naka, Y; Restaino, S; Takayama, H; Takeda, K, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Hoemann, B | 1 |
| Takayama, H | 2 |
| Jennings, DL | 1 |
| Han, J | 2 |
| Ando, M | 1 |
| Restaino, S | 1 |
| Colombo, P | 2 |
| Farr, M | 2 |
| Naka, Y | 2 |
| Takeda, K | 2 |
| Wright, M | 1 |
| Mauro, C | 1 |
| Jennings, D | 1 |
| Kurlansky, P | 1 |
| Truby, L | 1 |
| Stein, S | 1 |
| Topkara, V | 1 |
| Garan, AR | 1 |
| Yuzefpolskaya, M | 1 |
| Nicoara, A | 1 |
| Ruffin, D | 1 |
| Cooter, M | 1 |
| Patel, CB | 1 |
| Thompson, A | 1 |
| Schroder, JN | 1 |
| Daneshmand, MA | 1 |
| Hernandez, AF | 1 |
| Rogers, JG | 1 |
| Podgoreanu, MV | 1 |
| Swaminathan, M | 1 |
| Kretzer, A | 1 |
| Stafford-Smith, M | 1 |
| Milano, CA | 1 |
| Bartz, RR | 1 |
3 other studies available for amiodarone and Primary Graft Dysfunction
| Article | Year |
|---|---|
Discontinuing amiodarone treatment prior to heart transplantation lowers incidence of severe primary graft dysfunction.
Topics: Adult; Amiodarone; Heart Transplantation; Humans; Incidence; Primary Graft Dysfunction; Retrospectiv | 2020 |
Dose-dependent association between amiodarone and severe primary graft dysfunction in orthotopic heart transplantation.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Female; Follow-Up Studi | 2017 |
Primary graft dysfunction after heart transplantation: Incidence, trends, and associated risk factors.
Topics: Adult; Amiodarone; Female; Heart Transplantation; Humans; Incidence; Male; Middle Aged; Primary Graf | 2018 |