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amiodarone and Porphyrias

amiodarone has been researched along with Porphyrias in 2 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone (AD) is an effective antidysrythmic drug, however, there can be serious side effects, such as hepatic and neurological alterations, as well as skin photosensitization, as seen in porphyrias."7.70Amiodarone is a pharmacologically safe drug for porphyrias. ( Batlle, A; Enríquez de Salamanca, R; Méndez, M; Parera, V, 1999)
"Amiodarone (AD) is an effective antidysrythmic drug, however, there can be serious side effects, such as hepatic and neurological alterations, as well as skin photosensitization, as seen in porphyrias."3.70Amiodarone is a pharmacologically safe drug for porphyrias. ( Batlle, A; Enríquez de Salamanca, R; Méndez, M; Parera, V, 1999)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's1 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Méndez, M1
Parera, V1
Enríquez de Salamanca, R1
Batlle, A1
Parodi, A1
Guarrera, M1
Rebora, A1

Other Studies

2 other studies available for amiodarone and Porphyrias

ArticleYear
Amiodarone is a pharmacologically safe drug for porphyrias.
    General pharmacology, 1999, Volume: 32, Issue:2

    Topics: 5-Aminolevulinate Synthetase; Amiodarone; Ammonia-Lyases; Animals; Anti-Arrhythmia Agents; Feces; He

1999
Amiodarone-induced pseudoporphyria.
    Photo-dermatology, 1988, Volume: 5, Issue:3

    Topics: Aged; Amiodarone; Humans; Male; Porphyrias; Skin Diseases, Vesiculobullous

1988