Page last updated: 2024-10-22

amiodarone and Periphlebitis

amiodarone has been researched along with Periphlebitis in 13 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Periphlebitis: Periphlebitis is inflammation of the outer coat of a vein or of tissues surrounding the vein.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the effect of topical chamomile on the incidence of phlebitis due to the administration of an amiodarone infusion into the peripheral vein."9.24Efficacy of topical chamomile on the incidence of phlebitis due to an amiodarone infusion in coronary care patients: a double-blind, randomized controlled trial. ( Asefzadeh, S; Nassiri-Asl, M; Sharifi-Ardani, M; Yekefallah, L, 2017)
"Intravenous amiodarone is considered an effective treatment option for cardiac ventricular and atrial arrhythmias."9.24Effects of injection-site splinting on the incidence of phlebitis in patients taking peripherally infused amiodarone: A randomized clinical trial. ( Ayat-Isfahani, F; Davoudi, B; Jalali, A; Pashang, M; Sadeghian, S, 2017)
"Intravenous amiodarone is the gold-standard treatment for arrhythmias, but phlebitis is a common adverse effect."9.01Phlebitis in Intravenous Amiodarone Administration: Incidence and Contributing Factors. ( Moore, Z; Oragano, CA; Patton, D, 2019)
"To evaluate efficacy and safety of intravenous amiodarone for conversion of recent-onset atrial fibrillation."8.81Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials. ( Hilleman, DE; Spinler, SA, 2002)
"This evidence-based quality improvement initiative aimed to decrease and enhance early detection of phlebitis in patients receiving amiodarone."7.96Reducing the Incidence of Amiodarone-related Phlebitis Through Utilization of Evidence-based Practice. ( Fischer-Cartlidge, E; Murphy, J; Murphy, K, 2020)
"Intravenous amiodarone is an important treatment for arrhythmias, but peripheral infusion is associated with direct irritation of vessel walls and phlebitis rates of 8% to 55%."7.79Phlebitis in amiodarone administration: incidence, contributing factors, and clinical implications. ( Becker, N; Cotter, T; Forsey, L; Haynes, A; Matsuda, K; Norton, L; Ottoboni, LK; Pummer, E; Varady, A; Wang, P; Yang-Lu, CY, 2013)
"Nurses noted that the rate of phlebitis was high when intravenous amiodarone was infused via a peripheral site."7.78Incidence and severity of phlebitis in patients receiving peripherally infused amiodarone. ( Boyce, BA; Yee, BH, 2012)
"Postoperative atrial fibrillation following cardiothoracic surgery is common and frequently managed with intravenous (IV) amiodarone."7.74The incidence of phlebitis with intravenous amiodarone at guideline dose recommendations. ( Boyd, SY; Duffy, B; Roth, JE; Rubal, BJ; Slim, AM, 2007)
"The aim of this study was to evaluate the effect of topical chamomile on the incidence of phlebitis due to the administration of an amiodarone infusion into the peripheral vein."5.24Efficacy of topical chamomile on the incidence of phlebitis due to an amiodarone infusion in coronary care patients: a double-blind, randomized controlled trial. ( Asefzadeh, S; Nassiri-Asl, M; Sharifi-Ardani, M; Yekefallah, L, 2017)
"Intravenous amiodarone is considered an effective treatment option for cardiac ventricular and atrial arrhythmias."5.24Effects of injection-site splinting on the incidence of phlebitis in patients taking peripherally infused amiodarone: A randomized clinical trial. ( Ayat-Isfahani, F; Davoudi, B; Jalali, A; Pashang, M; Sadeghian, S, 2017)
"Intravenous amiodarone is the gold-standard treatment for arrhythmias, but phlebitis is a common adverse effect."5.01Phlebitis in Intravenous Amiodarone Administration: Incidence and Contributing Factors. ( Moore, Z; Oragano, CA; Patton, D, 2019)
"To evaluate efficacy and safety of intravenous amiodarone for conversion of recent-onset atrial fibrillation."4.81Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials. ( Hilleman, DE; Spinler, SA, 2002)
"This evidence-based quality improvement initiative aimed to decrease and enhance early detection of phlebitis in patients receiving amiodarone."3.96Reducing the Incidence of Amiodarone-related Phlebitis Through Utilization of Evidence-based Practice. ( Fischer-Cartlidge, E; Murphy, J; Murphy, K, 2020)
"Intravenous amiodarone is an important treatment for arrhythmias, but peripheral infusion is associated with direct irritation of vessel walls and phlebitis rates of 8% to 55%."3.79Phlebitis in amiodarone administration: incidence, contributing factors, and clinical implications. ( Becker, N; Cotter, T; Forsey, L; Haynes, A; Matsuda, K; Norton, L; Ottoboni, LK; Pummer, E; Varady, A; Wang, P; Yang-Lu, CY, 2013)
"Nurses noted that the rate of phlebitis was high when intravenous amiodarone was infused via a peripheral site."3.78Incidence and severity of phlebitis in patients receiving peripherally infused amiodarone. ( Boyce, BA; Yee, BH, 2012)
"Postoperative atrial fibrillation following cardiothoracic surgery is common and frequently managed with intravenous (IV) amiodarone."3.74The incidence of phlebitis with intravenous amiodarone at guideline dose recommendations. ( Boyd, SY; Duffy, B; Roth, JE; Rubal, BJ; Slim, AM, 2007)
"Amiodarone (AM) is a drug commonly used in patients with ventricular arrhythmias."1.91Protective effect of isoliquiritigenin in amiodarone-induced damage of human umbilical vein endothelial cells. ( Chang, YQ; Guo, JL; Guo, XJ; Han, X; Wang, JJ; Yan, XY; Zhang, BL, 2023)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.69)18.7374
1990's1 (7.69)18.2507
2000's2 (15.38)29.6817
2010's7 (53.85)24.3611
2020's2 (15.38)2.80

Authors

AuthorsStudies
Guo, JL1
Han, X1
Yan, XY1
Wang, JJ1
Chang, YQ1
Zhang, BL1
Guo, XJ1
Murphy, K1
Murphy, J1
Fischer-Cartlidge, E1
Sharifi-Ardani, M1
Yekefallah, L1
Asefzadeh, S1
Nassiri-Asl, M1
Oragano, CA1
Patton, D1
Moore, Z1
Dixon, HA1
Hort, AL1
Wright, CM1
Norton, L1
Ottoboni, LK1
Varady, A1
Yang-Lu, CY1
Becker, N1
Cotter, T1
Pummer, E1
Haynes, A1
Forsey, L1
Matsuda, K1
Wang, P1
Hannibal, GB1
Ayat-Isfahani, F1
Pashang, M1
Davoudi, B1
Sadeghian, S1
Jalali, A1
Boyce, BA1
Yee, BH1
Slim, AM1
Roth, JE1
Duffy, B1
Boyd, SY1
Rubal, BJ1
Hilleman, DE2
Spinler, SA1
Ward, GH1
Nolan, PE1
White, M1
Yalkowsky, SH1
Hansen, JM1
Mohiuddin, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Using Time-dependent Intravenous Infusions of Amiodarone for Conversions to Sinus Rhythms in Patients With Paroxysmal Atrial Fibrillation[NCT03432663]Phase 460 participants (Actual)Interventional2008-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amiodarone and Periphlebitis

ArticleYear
Phlebitis in Intravenous Amiodarone Administration: Incidence and Contributing Factors.
    Critical care nurse, 2019, Volume: 39, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Incidence; Infusions, Intravenous; Phlebitis; Severity o

2019
Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials.
    Pharmacotherapy, 2002, Volume: 22, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cohort Studies; Humans; Hypote

2002

Trials

2 trials available for amiodarone and Periphlebitis

ArticleYear
Efficacy of topical chamomile on the incidence of phlebitis due to an amiodarone infusion in coronary care patients: a double-blind, randomized controlled trial.
    Journal of integrative medicine, 2017, Volume: 15, Issue:5

    Topics: Administration, Topical; Amiodarone; Chamomile; Double-Blind Method; Female; Humans; Incidence; Infu

2017
Effects of injection-site splinting on the incidence of phlebitis in patients taking peripherally infused amiodarone: A randomized clinical trial.
    Journal of vascular nursing : official publication of the Society for Peripheral Vascular Nursing, 2017, Volume: 35, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Female; Humans; Incidence; Infusions

2017

Other Studies

9 other studies available for amiodarone and Periphlebitis

ArticleYear
Protective effect of isoliquiritigenin in amiodarone-induced damage of human umbilical vein endothelial cells.
    Immunity, inflammation and disease, 2023, Volume: 11, Issue:11

    Topics: Amiodarone; Chalcones; Human Umbilical Vein Endothelial Cells; Humans; Phlebitis

2023
Reducing the Incidence of Amiodarone-related Phlebitis Through Utilization of Evidence-based Practice.
    Worldviews on evidence-based nursing, 2020, Volume: 17, Issue:5

    Topics: Amiodarone; Evidence-Based Practice; Humans; Incidence; Infusions, Intravenous; Phlebitis; Quality I

2020
Amiodarone-induced phlebitis remains an issue in spite of measures to reduce its occurrence.
    The journal of vascular access, 2019, Volume: 20, Issue:6

    Topics: Aged; Amiodarone; Child, Preschool; Female; Humans; Incidence; Infant; Infant, Newborn; Infusions, I

2019
Phlebitis in amiodarone administration: incidence, contributing factors, and clinical implications.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2013, Volume: 22, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; California; Cardiac Care Facilit

2013
Peripheral Phlebitis Related to Amiodarone Infusion.
    AACN advanced critical care, 2016, Volume: 27, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Critical Care Nursing; Humans; Phlebitis; P

2016
Incidence and severity of phlebitis in patients receiving peripherally infused amiodarone.
    Critical care nurse, 2012, Volume: 32, Issue:4

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheterization, P

2012
The incidence of phlebitis with intravenous amiodarone at guideline dose recommendations.
    Military medicine, 2007, Volume: 172, Issue:12

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Humans; Incidence; Infusions,

2007
Studies in phlebitis. II. Early detection of amiodarone-induced phlebitis in a rabbit model.
    Pharmaceutical research, 1991, Volume: 8, Issue:6

    Topics: Amiodarone; Animals; Body Temperature; Ear, External; Phlebitis; Rabbits

1991
Amiodarone-induced infusion phlebitis.
    Clinical pharmacy, 1987, Volume: 6, Issue:5

    Topics: Aged; Aged, 80 and over; Amiodarone; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Phle

1987