amiodarone has been researched along with Papilledema in 18 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Papilledema: Swelling of the OPTIC DISK, usually in association with increased intracranial pressure, characterized by hyperemia, blurring of the disk margins, microhemorrhages, blind spot enlargement, and engorgement of retinal veins. Chronic papilledema may cause OPTIC ATROPHY and visual loss. (Miller et al., Clinical Neuro-Ophthalmology, 4th ed, p175)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We described two cases with papilledema within the first months of amiodarone treatment." | 4.84 | [Amiodarone associated optic neuropathies--two cases reports]. ( Andris, C; Collignon, N; Van Elmbt, G, 2007) |
| "Disc swelling and hemorrhages appeared in three eyes of two men receiving amiodarone hydrochloride for cardiac arrhythmias." | 3.67 | Papillopathy caused by amiodarone. ( Asdourian, GK; Gittinger, JW, 1987) |
| "Amiodarone is an excellent antiarrhythmic medication; however, it has numerous systemic and ocular adverse effects." | 2.66 | Ocular Adverse Effects of Amiodarone: A Systematic Review of Case Reports. ( Alshehri, M; Joury, A, 2020) |
| " After ruling out intracranial hypertension, arteritic ischemic optic neuropathy, non-arteritic, and inflammatory bilateral papilledema, the diagnosis was toxic optic neuropathy." | 1.51 | [Amiodarone-induced optic neuropathy: A rare side effect]. ( Ambrosi, P; Arcani, R; Arnould, T; Chagny, M; Daumas, A; Gayet, S; Gobin, N; Micallef, J; Pellerey, M; Rouby, F; Scapin, J; Villani, P, 2019) |
| "Amiodarone is a commonly prescribed and one of the most effective anti-arrhythmic drugs available." | 1.39 | Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone. ( Falck, A; Hautala, N; Hurskainen, M; Kervinen, M, 2013) |
| "Amiodarone was discontinued and the optic disc edema completely resolved over 15 months." | 1.33 | Regression of bilateral optic disc edema after discontinuation of amiodarone. ( Frohman, LP; Shinder, R; Turbin, RE, 2006) |
| "Amiodarone therapy was then discontinued, but there was no considerable improvement and after 6 weeks visual loss occurred in the left eye as well." | 1.31 | [First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?]. ( Gerke, E; Uebermuth, CA, 2002) |
| "Optic neuropathy has been reported to occur during antiarrhythmic therapy with amiodarone." | 1.31 | [Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy]. ( Gerling, J; Hansen, LL; Leifert, D, 2000) |
| "Amiodarone has been used for the last 20 years, initially as antianginal and then as antiarrhythmic agent." | 1.28 | [Optic neuropathy caused by amiodarone]. ( Ferreiro, JL; Isern Longares, JA; Ramón Moya, AF, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.11) | 18.7374 |
| 1990's | 4 (22.22) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Arcani, R | 1 |
| Pellerey, M | 1 |
| Rouby, F | 1 |
| Gobin, N | 1 |
| Scapin, J | 1 |
| Chagny, M | 1 |
| Arnould, T | 1 |
| Ambrosi, P | 1 |
| Gayet, S | 1 |
| Micallef, J | 1 |
| Villani, P | 1 |
| Daumas, A | 1 |
| Alshehri, M | 1 |
| Joury, A | 1 |
| Kervinen, M | 1 |
| Falck, A | 1 |
| Hurskainen, M | 1 |
| Hautala, N | 1 |
| Le-Nguyen, XT | 1 |
| Lee, TK | 1 |
| Do, DV | 1 |
| Sepah, YJ | 1 |
| Nguyen, QD | 1 |
| Rao, NA | 1 |
| Vasconcelos-Santos, DV | 1 |
| Goldstein, DA | 1 |
| Uebermuth, CA | 1 |
| Gerke, E | 1 |
| Aït Ali, F | 1 |
| Grolleau-Raoux, F | 1 |
| Arnaud, B | 1 |
| Schmitt-Bernard, CF | 1 |
| Charles, PE | 1 |
| Doise, JM | 1 |
| Quenot, JP | 1 |
| Muller, G | 1 |
| Aube, H | 1 |
| Baudouin, N | 1 |
| Piard, F | 1 |
| Besancenot, JF | 1 |
| Blettery, B | 1 |
| Shinder, R | 1 |
| Frohman, LP | 1 |
| Turbin, RE | 1 |
| Van Elmbt, G | 1 |
| Andris, C | 1 |
| Collignon, N | 1 |
| Borruat, FX | 1 |
| Regli, F | 1 |
| Gobbelé, R | 1 |
| Dahlke, C | 1 |
| Mull, M | 1 |
| Schwarz, M | 1 |
| Sreih, AG | 1 |
| Schoenfeld, MH | 1 |
| Marieb, MA | 1 |
| Speicher, MA | 1 |
| Goldman, MH | 1 |
| Chrousos, GA | 1 |
| Leifert, D | 1 |
| Hansen, LL | 1 |
| Gerling, J | 1 |
| Kristin, N | 1 |
| Ulbig, M | 1 |
| Ferreiro, JL | 1 |
| Isern Longares, JA | 1 |
| Ramón Moya, AF | 1 |
| Gittinger, JW | 2 |
| Asdourian, GK | 2 |
3 reviews available for amiodarone and Papilledema
| Article | Year |
|---|---|
Ocular Adverse Effects of Amiodarone: A Systematic Review of Case Reports.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Case-Control Studies; Corneal Diseases; | 2020 |
[Amiodarone associated optic neuropathies--two cases reports].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Papilledema | 2007 |
[Amiodarone-induced bilateral optic atrophy--a case report].
Topics: Aged; Amiodarone; Female; Humans; Optic Atrophy; Papilledema; Prednisolone; Sick Sinus Syndrome; Tre | 1999 |
15 other studies available for amiodarone and Papilledema
| Article | Year |
|---|---|
[Amiodarone-induced optic neuropathy: A rare side effect].
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Iatrogenic Disease; Optic Ner | 2019 |
Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Blindness; Female; Humans; Optic Nerve Diseases; Papillede | 2013 |
Diagnostic and therapeutic challenges.
Topics: Adult; Amiodarone; Central Nervous System Diseases; Diagnosis, Differential; Glucocorticoids; Humans | 2011 |
[First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blindness; Dose-Response Relationshi | 2002 |
[Amiodarone and disk edema: physiopathological debate based on a case report].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Papilledema | 2003 |
Amiodarone-related acute respiratory distress syndrome following sudden withdrawal of steroids.
Topics: Adrenal Cortex Hormones; Aged; Amiodarone; Anti-Arrhythmia Agents; Bronchoalveolar Lavage Fluid; Fat | 2006 |
Regression of bilateral optic disc edema after discontinuation of amiodarone.
Topics: Amiodarone; Female; Follow-Up Studies; Humans; Middle Aged; Myocardial Infarction; Papilledema; Subs | 2006 |
Pseudotumor cerebri as a complication of amiodarone therapy.
Topics: Amiodarone; Atrial Fibrillation; Fundus Oculi; Humans; Male; Middle Aged; Papilledema; Pseudotumor C | 1993 |
Optic neuropathy following amiodarone therapy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Follow-Up Studies; Human | 1999 |
Amiodarone optic neuropathy without disc edema.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Middle Aged; Optic Nerve; Optic Nerve Diseases; Pa | 2000 |
[Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Humans; Male; Middle Aged; Optic | 2000 |
[Acute papilledema. A 69-year-old patient with acute bilateral papilledema].
Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Follow-Up Studies; Humans; Male; Papilledem | 2001 |
[Optic neuropathy caused by amiodarone].
Topics: Amiodarone; Animals; Cardiac Complexes, Premature; Demyelinating Diseases; Humans; Male; Middle Aged | 1990 |
Amiodarone-related optic neuropathy.
Topics: Amiodarone; Humans; Papilledema | 1988 |
Papillopathy caused by amiodarone.
Topics: Amiodarone; Arrhythmias, Cardiac; Drug Therapy, Combination; Eye Hemorrhage; Humans; Male; Middle Ag | 1987 |