amiodarone has been researched along with Optic Neuropathy, Ischemic in 12 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Optic Neuropathy, Ischemic: Ischemic injury to the OPTIC NERVE which usually affects the OPTIC DISK (optic neuropathy, anterior ischemic) and less frequently the retrobulbar portion of the nerve (optic neuropathy, posterior ischemic). The injury results from occlusion of arterial blood supply which may result from TEMPORAL ARTERITIS; ATHEROSCLEROSIS; COLLAGEN DISEASES; EMBOLISM; DIABETES MELLITUS; and other conditions. The disease primarily occurs in the sixth decade or later and presents with the sudden onset of painless and usually severe monocular visual loss. Anterior ischemic optic neuropathy also features optic disk edema with microhemorrhages. The optic disk appears normal in posterior ischemic optic neuropathy. (Glaser, Neuro-Ophthalmology, 2nd ed, p135)
| Excerpt | Relevance | Reference |
|---|---|---|
| "To report clinical features of amiodarone-induced optic neuropathy and outline the differentiation of amiodarone optic neuropathy from nonarteritic anterior ischemic optic neuropathy." | 3.70 | Features of amiodarone-induced optic neuropathy. ( Fraunfelder, FT; Macaluso, DC; Shults, WT, 1999) |
| "The authors present an account on an uncommon case when damage of visual functions of a patient were due to two independent cause: amiodarone neuropathy of the optic nerve (ANO) and an intracranial tumour-a craniopharyngioma." | 3.69 | [Amiodarone neuropathy of the optic nerve from the viewpoint of the neuro-ophthalmologist]. ( Hobza, V; Jirásková, N; Rozsíval, P, 1996) |
| "Treatment with amiodarone should be discontinued after exclusion of life-threatening situations by a cardiologist, as soon as the first changes of the optic disc occur." | 2.42 | [Amiodarone treatment and visual prognosis]. ( Schmidt, D, 2003) |
| "Optic neuropathy has been reported to occur during antiarrhythmic therapy with amiodarone." | 1.31 | [Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy]. ( Gerling, J; Hansen, LL; Leifert, D, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 8 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (8.33) | 2.80 |
| Authors | Studies |
|---|---|
| Mitchell, R | 1 |
| Chacko, J | 1 |
| Schmidt, D | 1 |
| Fraunfelder, FW | 1 |
| Shults, T | 1 |
| Hayreh, SS | 1 |
| Verit, A | 1 |
| Younge, BR | 1 |
| Jirásková, N | 1 |
| Rozsíval, P | 1 |
| Hobza, V | 1 |
| Palimar, P | 1 |
| Cota, N | 1 |
| Macaluso, DC | 1 |
| Shults, WT | 1 |
| Fraunfelder, FT | 1 |
| Leifert, D | 1 |
| Hansen, LL | 1 |
| Gerling, J | 1 |
| Polak, BC | 1 |
| Tutein Nolthenius, PA | 1 |
| Rietveld, E | 1 |
| Verslegers, W | 1 |
| De Deyn, PP | 1 |
2 reviews available for amiodarone and Optic Neuropathy, Ischemic
| Article | Year |
|---|---|
Clinical and Mechanistic Review of Amiodarone-Associated Optic Neuropathy.
Topics: Amiodarone; Humans; Insulin-Like Growth Factor I; Optic Nerve; Optic Nerve Diseases; Optic Neuropath | 2022 |
[Amiodarone treatment and visual prognosis].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Femal | 2003 |
10 other studies available for amiodarone and Optic Neuropathy, Ischemic
| Article | Year |
|---|---|
Non-arteritic anterior ischemic optic neuropathy, erectile dysfunction drugs, and amiodarone: is there a relationship?
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amiodarone; Erectile Dysfunction; Humans; Male; Optic Neuropath | 2006 |
Amiodarone, erectile dysfunction drugs, and non-arteritic ischemic optic neuropathy.
Topics: Amiodarone; Erectile Dysfunction; Humans; Male; Optic Neuropathy, Ischemic; Risk Factors; Vasodilato | 2006 |
Non-arteritic anterior ischemic optic neuropathy, PDE-5 inhibitors, and amiodarone: may there be a sex hormone effect for the eye?
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Amiodarone; Cyclic Nucleotide Phosphodiesterases, Type 5; Eye; | 2007 |
Amiodarone and ischemic optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Optic Neuropathy, Ischemic; Risk F | 2007 |
[Amiodarone neuropathy of the optic nerve from the viewpoint of the neuro-ophthalmologist].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Craniopharyngioma; Humans; Male; Optic Nerve Diseases; Opt | 1996 |
Bilateral anterior ischaemic optic neuropathy following amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Middle Aged; Optic Neuropathy, Ischemic; Vasodilat | 1998 |
Features of amiodarone-induced optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Fundus Oculi; Humans; Optic Nerve; Opti | 1999 |
[Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Humans; Male; Middle Aged; Optic | 2000 |
[Visual impairment due to optic neuropathy in 2 patients on amiodarone therapy, i.e. ethambutol and isoniazide].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Humans; Male; Middle Aged | 2001 |
[Visual impairment due to optic neuropathy in 2 patients on amiodarone, and ethambutol and isoniazide therapy, respectively].
Topics: Amiodarone; Anti-Arrhythmia Agents; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Fema | 2001 |