amiodarone has been researched along with Optic Nerve Diseases in 44 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Optic Nerve Diseases: Conditions which produce injury or dysfunction of the second cranial or optic nerve, which is generally considered a component of the central nervous system. Damage to optic nerve fibers may occur at or near their origin in the retina, at the optic disk, or in the nerve, optic chiasm, optic tract, or lateral geniculate nuclei. Clinical manifestations may include decreased visual acuity and contrast sensitivity, impaired color vision, and an afferent pupillary defect.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to describe a case of optic neuropathy after substitution of amiodarone with dronedarone for treatment of atrial fibrillation." | 7.96 | Case Report: Presumed Optic Neuropathy after Amiodarone and then Dronedarone for Treatment of Atrial Fibrillation. ( Maharshak, I; Paul, M; Steiner, H, 2020) |
| "This study aimed to describe a case of optic neuropathy after substitution of amiodarone with dronedarone for treatment of atrial fibrillation." | 3.96 | Case Report: Presumed Optic Neuropathy after Amiodarone and then Dronedarone for Treatment of Atrial Fibrillation. ( Maharshak, I; Paul, M; Steiner, H, 2020) |
| "To report clinical features of amiodarone-induced optic neuropathy and outline the differentiation of amiodarone optic neuropathy from nonarteritic anterior ischemic optic neuropathy." | 3.70 | Features of amiodarone-induced optic neuropathy. ( Fraunfelder, FT; Macaluso, DC; Shults, WT, 1999) |
| "The authors present an account on an uncommon case when damage of visual functions of a patient were due to two independent cause: amiodarone neuropathy of the optic nerve (ANO) and an intracranial tumour-a craniopharyngioma." | 3.69 | [Amiodarone neuropathy of the optic nerve from the viewpoint of the neuro-ophthalmologist]. ( Hobza, V; Jirásková, N; Rozsíval, P, 1996) |
| "Damage of the optic nerve (optic neuropathy) may be caused, apart from other reasons, by an adverse drug effect." | 2.44 | [Adverse effect optic neuropathy]. ( Martini, BC, 2008) |
| "The optic nerve is quite vulnerable to the toxic effect of drugs." | 2.44 | [Toxicity of recent and less recent drugs on the optic nerve. Does Viagra cause blindness?]. ( Cordonnier, M, 2007) |
| "The term optic neuropathy is used to describe optic nerve damage caused by any of four main etiologies: ischemic, hereditary, nutritional and toxic." | 2.44 | Drug-induced optic neuropathies. ( Fraunfelder, FW; Lloyd, MJ, 2007) |
| "Treatment with amiodarone should be discontinued after exclusion of life-threatening situations by a cardiologist, as soon as the first changes of the optic disc occur." | 2.42 | [Amiodarone treatment and visual prognosis]. ( Schmidt, D, 2003) |
| " Although several agents have ocular effects, amiodarone is the most widely recognized for producing adverse effects in the eyes." | 2.40 | Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations. ( Pollak, PT, 1999) |
| " After ruling out intracranial hypertension, arteritic ischemic optic neuropathy, non-arteritic, and inflammatory bilateral papilledema, the diagnosis was toxic optic neuropathy." | 1.51 | [Amiodarone-induced optic neuropathy: A rare side effect]. ( Ambrosi, P; Arcani, R; Arnould, T; Chagny, M; Daumas, A; Gayet, S; Gobin, N; Micallef, J; Pellerey, M; Rouby, F; Scapin, J; Villani, P, 2019) |
| "Amiodarone is a commonly prescribed and one of the most effective anti-arrhythmic drugs available." | 1.39 | Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone. ( Falck, A; Hautala, N; Hurskainen, M; Kervinen, M, 2013) |
| "Amiodarone was discontinued after discussion with the patient's cardiologist." | 1.32 | Amiodarone induced optic neuropathy. ( Castillo, I; Foroozan, R; Nagra, PK; Savino, PJ; Sergott, RC, 2003) |
| "Amiodarone therapy was then discontinued, but there was no considerable improvement and after 6 weeks visual loss occurred in the left eye as well." | 1.31 | [First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?]. ( Gerke, E; Uebermuth, CA, 2002) |
| "Optic neuropathy has been reported to occur during antiarrhythmic therapy with amiodarone." | 1.31 | [Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy]. ( Gerling, J; Hansen, LL; Leifert, D, 2000) |
| "Amiodarone has been used for the last 20 years, initially as antianginal and then as antiarrhythmic agent." | 1.28 | [Optic neuropathy caused by amiodarone]. ( Ferreiro, JL; Isern Longares, JA; Ramón Moya, AF, 1990) |
| "Amiodarone has been implicated in the pathogenesis of optic neuropathy in several cases." | 1.27 | Optic nerve ultrastructure following amiodarone therapy. ( Mansour, AM; O'Grady, R; Puklin, JE, 1988) |
| "Appearance of optic neuropathy is probably a relative indication for discontinuing the use of the drug, in the hopes of avoiding bilateral involvement or perhaps recovering vision." | 1.27 | Optic neuropathy and amiodarone therapy. ( Feiner, LA; Fraunfelder, FT; Kazmier, FJ; Stricker, BH; Younge, BR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.36) | 18.7374 |
| 1990's | 5 (11.36) | 18.2507 |
| 2000's | 19 (43.18) | 29.6817 |
| 2010's | 11 (25.00) | 24.3611 |
| 2020's | 4 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Mitchell, R | 1 |
| Chacko, J | 1 |
| Bayrakçeken, K | 1 |
| Ucgul, RK | 1 |
| Coban, T | 1 |
| Yazıcı, G | 1 |
| Suleyman, H | 1 |
| Arcani, R | 1 |
| Pellerey, M | 1 |
| Rouby, F | 1 |
| Gobin, N | 1 |
| Scapin, J | 1 |
| Chagny, M | 1 |
| Arnould, T | 1 |
| Ambrosi, P | 1 |
| Gayet, S | 1 |
| Micallef, J | 1 |
| Villani, P | 1 |
| Daumas, A | 1 |
| Maharshak, I | 1 |
| Paul, M | 1 |
| Steiner, H | 1 |
| Tan, Y | 1 |
| Sia, P | 1 |
| Simon, S | 1 |
| Kervinen, M | 1 |
| Falck, A | 1 |
| Hurskainen, M | 1 |
| Hautala, N | 1 |
| Chassang, B | 1 |
| Bonnin, N | 1 |
| Moisset, X | 1 |
| Citron, B | 1 |
| Clavelou, P | 1 |
| Chiambaretta, F | 1 |
| Mindel, JS | 3 |
| Cheng, HC | 1 |
| Yeh, HJ | 1 |
| Huang, N | 1 |
| Chou, YJ | 1 |
| Yen, MY | 1 |
| Wang, AG | 1 |
| Bagiella, E | 1 |
| Knudsen, A | 1 |
| Wasinska-Borowiec, W | 1 |
| Aghdam, KA | 1 |
| Saari, JM | 1 |
| Grzybowski, A | 1 |
| Martini, BC | 1 |
| Passman, RS | 1 |
| Bennett, CL | 1 |
| Purpura, JM | 1 |
| Kapur, R | 1 |
| Johnson, LN | 2 |
| Raisch, DW | 1 |
| West, DP | 1 |
| Edwards, BJ | 1 |
| Belknap, SM | 1 |
| Liebling, DB | 1 |
| Fisher, MJ | 1 |
| Samaras, AT | 1 |
| Jones, LG | 1 |
| Tulas, KM | 1 |
| McKoy, JM | 1 |
| Ciechanowski, PP | 1 |
| Töteberg-Harms, M | 1 |
| Stürmer, J | 1 |
| Kunz, M | 1 |
| Landau, K | 1 |
| Sturm, V | 1 |
| Selvaraj, V | 1 |
| Johnson, KG | 1 |
| Uebermuth, CA | 1 |
| Gerke, E | 1 |
| Nagra, PK | 1 |
| Foroozan, R | 1 |
| Savino, PJ | 1 |
| Castillo, I | 1 |
| Sergott, RC | 1 |
| Schmidt, D | 1 |
| Domingues, MF | 1 |
| Barros, H | 1 |
| Falcão-Reis, FM | 1 |
| Chen, D | 1 |
| Hedges, TR | 1 |
| Krohel, GB | 1 |
| Thomas, ER | 1 |
| Clement, CI | 1 |
| Myers, P | 1 |
| Tan, KP | 1 |
| Turdumambetova, G | 1 |
| Bredehorn, T | 1 |
| Duncker, GI | 1 |
| Murphy, MA | 1 |
| Murphy, JF | 1 |
| Purvin, V | 1 |
| Kawasaki, A | 1 |
| Borruat, FX | 1 |
| Fraunfelder, FW | 2 |
| Fraunfelder, FT | 3 |
| Cordonnier, M | 1 |
| Lloyd, MJ | 1 |
| Jirásková, N | 1 |
| Rozsíval, P | 1 |
| Hobza, V | 1 |
| Seemongal-Dass, RR | 1 |
| Spencer, SR | 1 |
| Macaluso, DC | 1 |
| Shults, WT | 1 |
| Pollak, PT | 1 |
| Speicher, MA | 1 |
| Goldman, MH | 1 |
| Chrousos, GA | 1 |
| Leifert, D | 1 |
| Hansen, LL | 1 |
| Gerling, J | 1 |
| Polak, BC | 1 |
| Tutein Nolthenius, PA | 1 |
| Rietveld, E | 1 |
| Verslegers, W | 1 |
| De Deyn, PP | 1 |
| Ferreiro, JL | 1 |
| Isern Longares, JA | 1 |
| Ramón Moya, AF | 1 |
| Nazarian, SM | 1 |
| Jay, WM | 1 |
| Younge, BR | 2 |
| Mansour, AM | 1 |
| Puklin, JE | 1 |
| O'Grady, R | 1 |
| Dewachter, A | 1 |
| Lievens, H | 1 |
| Feiner, LA | 1 |
| Kazmier, FJ | 1 |
| Stricker, BH | 1 |
14 reviews available for amiodarone and Optic Nerve Diseases
| Article | Year |
|---|---|
Clinical and Mechanistic Review of Amiodarone-Associated Optic Neuropathy.
Topics: Amiodarone; Humans; Insulin-Like Growth Factor I; Optic Nerve; Optic Nerve Diseases; Optic Neuropath | 2022 |
An Updated Review on the Most Common Agents Causing Toxic Optic Neuropathies.
Topics: Amiodarone; Erythropoietin; Ethambutol; Humans; Linezolid; Methanol; Optic Nerve Diseases; Phosphodi | 2017 |
[Adverse effect optic neuropathy].
Topics: Acetamides; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antitubercular Agents; Drug-R | 2008 |
Amiodarone-associated optic neuropathy: a critical review.
Topics: Amiodarone; Anti-Arrhythmia Agents; Blindness; Humans; Optic Nerve Diseases | 2012 |
Dronedarone-induced optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Dronedarone; Humans; Male; Optic Nerve Diseases | 2013 |
[Amiodarone treatment and visual prognosis].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Femal | 2003 |
Amiodarone optic neuropathy--review.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Optic Nerve Diseases | 2003 |
The clinical spectrum of amiodarone-associated optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Mi | 2004 |
Bilateral optic neuropathy due to amiodarone with recurrence.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Male; Optic Nerve Diseases; R | 2005 |
[Ocular side-effects associated with amiodarone therapy].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Corneal Opacity; Dose-Response Re | 2005 |
Amiodarone and optic neuropathy: the heart of the matter.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Optic Nerve Diseases; Registries | 2005 |
[Toxicity of recent and less recent drugs on the optic nerve. Does Viagra cause blindness?].
Topics: Acetamides; Amiodarone; Blindness; Ethambutol; Humans; Immunosuppressive Agents; Interferon-alpha; L | 2007 |
Drug-induced optic neuropathies.
Topics: Acetamides; Adverse Drug Reaction Reporting Systems; Amiodarone; Anti-Arrhythmia Agents; Anti-Infect | 2007 |
Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Corneal Opacity; Diagnosis, Differential; Humans; Lung | 1999 |
30 other studies available for amiodarone and Optic Nerve Diseases
| Article | Year |
|---|---|
Effect of adenosine triphosphate on amiodarone-induced optic neuropathy in rats: biochemical and histopathological evaluation.
Topics: Adenosine Triphosphate; Amiodarone; Animals; Glutathione; Optic Nerve; Optic Nerve Diseases; Rats; R | 2023 |
[Amiodarone-induced optic neuropathy: A rare side effect].
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Iatrogenic Disease; Optic Ner | 2019 |
Case Report: Presumed Optic Neuropathy after Amiodarone and then Dronedarone for Treatment of Atrial Fibrillation.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Drug Substi | 2020 |
Optic neuropathy secondary to perhexiline and amiodarone.
Topics: Aged; Amiodarone; Fluorescein Angiography; Humans; Male; Optic Nerve Diseases; Perhexiline; Recurren | 2021 |
Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Blindness; Female; Humans; Optic Nerve Diseases; Papillede | 2013 |
Two cases of bilateral amiodarone-associated optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Middle Aged; Optic Nerve Diseases | 2014 |
Absence of amiodarone-associated optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Incidence; Optic Nerve Diseases; United States | 2014 |
Amiodarone-Associated Optic Neuropathy: A Nationwide Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Databases, Factual; | 2015 |
Re: Cheng et al.: Amiodarone-associated optic neuropathy: a nationwide study (Ophthalmology 2015;122:2553-9).
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Optic Nerve Diseases; Optic Neuritis | 2016 |
Short-term treatment with oral amiodarone resulting in bilateral optic neuropathy and permanent blindness.
Topics: Administration, Oral; Aftercare; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Blin | 2017 |
Amiodarone and optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Incidence; Optic Nerve Diseases; Un | 2008 |
Bilateral optic neuropathy after short-term treatment with intravenous amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Blindness; Humans; Injections, Intrave | 2012 |
[First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blindness; Dose-Response Relationshi | 2002 |
Amiodarone induced optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Color Perception; Fluorescein Angiography; Humans; Male; M | 2003 |
Amiodarone and optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Case-Control Studies; Contrast Sensitivity; Evoked Potenti | 2004 |
Optic neuropathy in patients using amiodarone.
Topics: Aged; Aged, 80 and over; Amiodarone; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Opt | 2006 |
Scientific challenges in postmarketing surveillance of ocular adverse drug reactions.
Topics: Adverse Drug Reaction Reporting Systems; Amiodarone; Chloramphenicol; Databases, Factual; Drug-Relat | 2007 |
[Amiodarone neuropathy of the optic nerve from the viewpoint of the neuro-ophthalmologist].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Craniopharyngioma; Humans; Male; Optic Nerve Diseases; Opt | 1996 |
Bilateral optic neuropathy linked with amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Follow-Up Studies; Humans; Male; Middle Aged; Optic Nerve Diseas | 1998 |
Features of amiodarone-induced optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Fundus Oculi; Humans; Optic Nerve; Opti | 1999 |
Amiodarone optic neuropathy without disc edema.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Middle Aged; Optic Nerve; Optic Nerve Diseases; Pa | 2000 |
[Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Humans; Male; Middle Aged; Optic | 2000 |
[Visual impairment due to optic neuropathy in 2 patients on amiodarone therapy, i.e. ethambutol and isoniazide].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Humans; Male; Middle Aged | 2001 |
[Visual impairment due to optic neuropathy in 2 patients on amiodarone, and ethambutol and isoniazide therapy, respectively].
Topics: Amiodarone; Anti-Arrhythmia Agents; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Fema | 2001 |
[Optic neuropathy caused by amiodarone].
Topics: Amiodarone; Animals; Cardiac Complexes, Premature; Demyelinating Diseases; Humans; Male; Middle Aged | 1990 |
Bilateral optic neuropathy associated with amiodarone therapy.
Topics: Amiodarone; Atrial Fibrillation; Humans; Male; Middle Aged; Ophthalmoscopy; Optic Atrophy; Optic Ner | 1988 |
Amiodarone optic neuropathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Disease Susceptibility; Humans; Optic Nerve Diseases | 1988 |
Optic nerve ultrastructure following amiodarone therapy.
Topics: Amiodarone; Choroid Neoplasms; Humans; Male; Melanoma; Microscopy, Electron; Middle Aged; Optic Nerv | 1988 |
Amiodarone and optic neuropathy.
Topics: Amiodarone; Female; Fluorescein Angiography; Humans; Male; Middle Aged; Optic Nerve Diseases; Vision | 1988 |
Optic neuropathy and amiodarone therapy.
Topics: Aged; Amiodarone; Female; Humans; Male; Middle Aged; Optic Nerve Diseases; Tachycardia; Vision Tests | 1987 |