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amiodarone and Obesity

amiodarone has been researched along with Obesity in 11 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Although oral amiodarone (AMD) has been used for the management of atrial fibrillation (AF), serious complications such as interstitial pneumonia (IP) occur very occasionally."7.83Obesity Is Associated With the Development of Interstitial Pneumonia Under Long-Term Administration of Amiodarone in Refractory Atrial Fibrillation Patients. ( Fujino, T; Fukunaga, S; Ikeda, T; Kinoshita, T; Kitahara, K; Kobayashi, K; Koike, H; Koike, M; Sato, H; Shinohara, M; Suzuki, T; Yuzawa, H, 2016)
"To evaluate the influence of obesity on pharmacokinetics of amiodarone (AMD) using Non-Linear Mixed Effects Modelling (NONMEM) in Japanese patients treated with oral therapy."7.75Effect of obesity on serum amiodarone concentration in Japanese patients: population pharmacokinetic investigation by multiple trough screen analysis. ( Araki, R; Fukuchi, H; Hayano, M; Komiya, N; Nakashima, M; Sasaki, H; Yano, K; Yukawa, E, 2009)
"Obesity is associated with an increased risk of development of chronic heart failure, but recent epidemiological studies indicate that a higher body mass index (BMI) is associated with a better survival rate."5.34[Combined therapy with weight loss and amiodarone improved cardiac function in a patient with idiopathic dilated cardiomyopathy complicated with severe obesity: a case report]. ( Kawano, S; Kozai, T; Tanaka, H; Urabe, Y, 2007)
"Although oral amiodarone (AMD) has been used for the management of atrial fibrillation (AF), serious complications such as interstitial pneumonia (IP) occur very occasionally."3.83Obesity Is Associated With the Development of Interstitial Pneumonia Under Long-Term Administration of Amiodarone in Refractory Atrial Fibrillation Patients. ( Fujino, T; Fukunaga, S; Ikeda, T; Kinoshita, T; Kitahara, K; Kobayashi, K; Koike, H; Koike, M; Sato, H; Shinohara, M; Suzuki, T; Yuzawa, H, 2016)
"Amiodarone has a high iodine content that can induce persistent iodine excess and may prevent radioiodine (RI) treatment."1.35Plasma exchanges overcome persistent iodine overload to enable 131I ablation of differentiated thyroid carcinoma. ( Dib-Deperrest, A; Hindie, E; Houzé, P; Moretti, JL; Parquet, N; Toubert, ME, 2008)
"Obesity is associated with an increased risk of development of chronic heart failure, but recent epidemiological studies indicate that a higher body mass index (BMI) is associated with a better survival rate."1.34[Combined therapy with weight loss and amiodarone improved cardiac function in a patient with idiopathic dilated cardiomyopathy complicated with severe obesity: a case report]. ( Kawano, S; Kozai, T; Tanaka, H; Urabe, Y, 2007)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's0 (0.00)18.2507
2000's3 (27.27)29.6817
2010's5 (45.45)24.3611
2020's1 (9.09)2.80

Authors

AuthorsStudies
Young, ML1
Exelbert, EJ1
Roth, T1
Cohen, L1
Cogan, J1
Abdussalam, A1
Al-Agili, M1
Al Nebaihi, HM1
Mayo, PR1
Gabr, RQ1
Brocks, DR1
Simşek, H1
Doğan, A1
Sahin, M1
Gümrükçüoğlu, HA1
Koike, H1
Fujino, T1
Koike, M1
Shinohara, M1
Kitahara, K1
Kinoshita, T1
Yuzawa, H1
Suzuki, T1
Sato, H1
Fukunaga, S1
Kobayashi, K1
Ikeda, T1
Fukuchi, H1
Nakashima, M1
Araki, R1
Komiya, N1
Hayano, M1
Yano, K1
Sasaki, H1
Yukawa, E1
Menzorov, MV1
Shutov, AM1
Serov, VA1
Schamroth, CL1
Tanaka, H1
Kawano, S1
Kozai, T1
Urabe, Y1
Toubert, ME1
Dib-Deperrest, A1
Houzé, P1
Parquet, N1
Hindie, E1
Moretti, JL1
Wartofsky, L1
Burman, KD1
Linquette, M1
Wemeau, JL1
Cappoen, JP1
Folliot, JP1

Reviews

1 review available for amiodarone and Obesity

ArticleYear
Alterations in thyroid function in patients with systemic illness: the "euthyroid sick syndrome".
    Endocrine reviews, 1982,Spring, Volume: 3, Issue:2

    Topics: Adult; Age Factors; Aged; Amiodarone; Animals; Anorexia Nervosa; Contrast Media; Diabetes Mellitus;

1982

Other Studies

10 other studies available for amiodarone and Obesity

ArticleYear
External Cardioversion-Defibrillation with Pushing Down on the Chest Wall to Increase the Success Rate in Obese Patients.
    The American journal of case reports, 2020, Nov-16, Volume: 21

    Topics: Adolescent; Aged; Amiodarone; Atrial Fibrillation; Electric Countershock; Female; Humans; Male; Midd

2020
Dietary-Induced Obesity and Changes in the Biodistribution and Metabolism of Amiodarone in the Rat.
    Journal of pharmaceutical sciences, 2018, Volume: 107, Issue:11

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cytochrome P450 Family 2; Diet, Carbohydrate Loading; D

2018
[A case of idiopathic ventricular tachycardia in a 14-year-old obese patient due to golden berry fruit extract pills for weight loss].
    Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir, 2013, Volume: 41, Issue:5

    Topics: Administration, Oral; Adolescent; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Elect

2013
Obesity Is Associated With the Development of Interstitial Pneumonia Under Long-Term Administration of Amiodarone in Refractory Atrial Fibrillation Patients.
    International heart journal, 2016, Volume: 57, Issue:1

    Topics: Administration, Oral; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillati

2016
Effect of obesity on serum amiodarone concentration in Japanese patients: population pharmacokinetic investigation by multiple trough screen analysis.
    Journal of clinical pharmacy and therapeutics, 2009, Volume: 34, Issue:3

    Topics: Administration, Oral; Adult; Age Factors; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agent

2009
[Total body water and recurrent atrial fibrillation].
    Terapevticheskii arkhiv, 2011, Volume: 83, Issue:12

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Body Mass Index; Body Water; Female; Humans

2011
The perils of pharmacological treatment for obesity: a case of sibutramine-associated cardiomyopathy and malignant arrhythmias.
    Cardiovascular journal of Africa, 2012, Mar-12, Volume: 23, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Appetite Depressants; Cardiomyopathy, Hypertrophic; Cyclobutanes

2012
[Combined therapy with weight loss and amiodarone improved cardiac function in a patient with idiopathic dilated cardiomyopathy complicated with severe obesity: a case report].
    Journal of cardiology, 2007, Volume: 50, Issue:2

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Body Mass Index; Cardiomyopathy, Dilated; Diet, Reducing;

2007
Plasma exchanges overcome persistent iodine overload to enable 131I ablation of differentiated thyroid carcinoma.
    Thyroid : official journal of the American Thyroid Association, 2008, Volume: 18, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Iodine; Iodine Radioisotopes; Lymphatic Metastasis; Male

2008
[Mechanisms of T4 hyperthyroidism].
    La Nouvelle presse medicale, 1980, Oct-11, Volume: 9, Issue:37

    Topics: Aged; Amiodarone; Fasting; Female; Humans; Hyperthyroidism; Obesity; Thyroxine; Triiodothyronine

1980