amiodarone has been researched along with Niemann-Pick Disease in 3 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone analogues were also studied, including the recently developed derivative dronedarone." | 1.37 | Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype. ( Baritussio, A; Bergonzini, V; Bigler, L; Calistri, A; Caretta, CM; Dal Zoppo, D; Del Vecchio, C; Faggin, E; Ha, HR; Nadai, M; Orlando, R; Palù, G; Pettenazzo, A; Piccoli, E; Salata, C, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Piccoli, E | 1 |
| Nadai, M | 1 |
| Caretta, CM | 1 |
| Bergonzini, V | 1 |
| Del Vecchio, C | 1 |
| Ha, HR | 1 |
| Bigler, L | 1 |
| Dal Zoppo, D | 1 |
| Faggin, E | 1 |
| Pettenazzo, A | 1 |
| Orlando, R | 1 |
| Salata, C | 1 |
| Calistri, A | 1 |
| Palù, G | 1 |
| Baritussio, A | 1 |
| Palmeri, S | 1 |
| Battisti, C | 1 |
| Malandrini, A | 1 |
| Federico, A | 1 |
| Brown, WJ | 1 |
| Sullivan, TR | 1 |
| Greenspan, P | 1 |
3 other studies available for amiodarone and Niemann-Pick Disease
| Article | Year |
|---|---|
Amiodarone impairs trafficking through late endosomes inducing a Niemann-Pick C-like phenotype.
Topics: Amiodarone; Androstenes; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Cholesterol; Dose-Respons | 2011 |
Amiodarone induced lipidosis similar to Niemann-Pick C disease. Biochemical and morphological study.
Topics: Amiodarone; Cells, Cultured; Cholesterol; Culture Media; Fibroblasts; Humans; Hydrolases; Kinetics; | 1995 |
Nile red staining of lysosomal phospholipid inclusions.
Topics: Amiodarone; Animals; Cells, Cultured; Cholesterol; Cholesterol Esters; Fluorescent Dyes; Humans; Inc | 1992 |