amiodarone has been researched along with Necrosis in 22 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A dose-dependent cutaneous leukocytoclastic vasculitis developed in a 34 year old man who was given amiodarone for supraventricular tachycardias resistant to other drugs." | 7.67 | Amiodarone-induced vasculitis and polyserositis. ( Bircher, J; Stäubli, M; Zimmermann, A, 1985) |
| "Amiodarone is a new and powerful antiarrhythmic agent currently under investigation in North America." | 5.27 | Acute necrotizing pneumonitis and hyperglycemia after amiodarone therapy. Case report and review of amiodarone-associated pulmonary disease. ( Pollak, PT; Sami, M, 1984) |
| "A dose-dependent cutaneous leukocytoclastic vasculitis developed in a 34 year old man who was given amiodarone for supraventricular tachycardias resistant to other drugs." | 3.67 | Amiodarone-induced vasculitis and polyserositis. ( Bircher, J; Stäubli, M; Zimmermann, A, 1985) |
| "Amiodarone (AM) is a potent antidysrhythmic agent that can cause potentially life-threatening pulmonary fibrosis, and N-desethylamiodarone (DEA), an AM metabolite, may contribute to AM toxicity." | 1.37 | Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells. ( Brien, JF; Massey, TE; Mulder, JE; Racz, WJ; Takahashi, T, 2011) |
| "Treatment with benzarone or benzbromarone can be associated with hepatic injury." | 1.33 | Mechanisms of benzarone and benzbromarone-induced hepatic toxicity. ( Gasser, R; Hänni, A; Kaufmann, P; Krähenbühl, S; Roberts, P; Török, M, 2005) |
| " The effect of the three least toxic amiodarone analogs on the human ether-a-go-go-related gene (hERG) channel was compared with amiodarone." | 1.33 | Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives. ( Brecht, K; Follath, F; Ha, HR; Konrad, D; Krähenbühl, S; Thomet, U; Török, M; Waldhauser, KM, 2006) |
| "To understand the bioavailability and mechanistic pathways of cytoprotection by IH636 grape seed proanthocyanidin extract (GSPE, commercially known as ActiVin) a series of in vitro and in vivo studies were conducted." | 1.31 | Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. ( Bagchi, D; Bagchi, M; Preuss, HG; Ray, SD; Stohs, SJ, 2002) |
| "Amiodarone is a new and powerful antiarrhythmic agent currently under investigation in North America." | 1.27 | Acute necrotizing pneumonitis and hyperglycemia after amiodarone therapy. Case report and review of amiodarone-associated pulmonary disease. ( Pollak, PT; Sami, M, 1984) |
| "Prolonged dosing of mice with amiodarone produced a myopathy characterized by autophagic vacuolation and phospholipid inclusions." | 1.27 | Changes in denervated skeletal muscle of amiodarone-fed mice. ( Brook, GA; Costa-Jussà, FR; Duchen, LW; Guevara, A; Jacobs, JM, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 3 (13.64) | 18.2507 |
| 2000's | 8 (36.36) | 29.6817 |
| 2010's | 2 (9.09) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, HY | 3 |
| Jacob, JS | 3 |
| Dunn, C | 3 |
| Muhammad, M | 3 |
| Kim, SJ | 3 |
| Grove, EL | 1 |
| Mulder, JE | 1 |
| Brien, JF | 1 |
| Racz, WJ | 1 |
| Takahashi, T | 1 |
| Massey, TE | 1 |
| Bagchi, D | 2 |
| Ray, SD | 2 |
| Bagchi, M | 1 |
| Preuss, HG | 1 |
| Stohs, SJ | 1 |
| Kaufmann, P | 1 |
| Török, M | 2 |
| Hänni, A | 1 |
| Roberts, P | 1 |
| Gasser, R | 1 |
| Krähenbühl, S | 2 |
| Bognar, Z | 1 |
| Kalai, T | 1 |
| Palfi, A | 1 |
| Hanto, K | 1 |
| Bognar, B | 1 |
| Mark, L | 1 |
| Szabo, Z | 1 |
| Tapodi, A | 1 |
| Radnai, B | 1 |
| Sarszegi, Z | 1 |
| Szanto, A | 1 |
| Gallyas, F | 1 |
| Hideg, K | 1 |
| Sumegi, B | 1 |
| Varbiro, G | 1 |
| Waldhauser, KM | 1 |
| Ha, HR | 1 |
| Thomet, U | 1 |
| Konrad, D | 1 |
| Brecht, K | 1 |
| Follath, F | 1 |
| Russell, SJ | 1 |
| Saltissi, S | 1 |
| Stockman, W | 1 |
| De Keyser, J | 1 |
| Brabant, S | 1 |
| Spoelders, K | 1 |
| Vuylsteke, P | 1 |
| Beeuwsaert, R | 1 |
| Coppé, E | 1 |
| Milei, J | 1 |
| Garcilazo, E | 1 |
| Bolomo, NJ | 1 |
| Molina, HA | 1 |
| Pollak, PT | 1 |
| Sami, M | 1 |
| Tosetti, C | 1 |
| Ongari, M | 1 |
| Evangelisti, A | 1 |
| Lolli, R | 1 |
| Napoli, A | 1 |
| Pitsiavas, V | 1 |
| Smerdely, P | 1 |
| Li, M | 1 |
| Boyages, SC | 1 |
| Galenko-Iaroshevskiĭ, PA | 1 |
| Melkumova, ER | 1 |
| Bartashevich, VV | 1 |
| Uvarov, AV | 1 |
| Turovaia, AIu | 1 |
| Khankoeva, AI | 1 |
| Galygo, DS | 1 |
| Patel, D | 1 |
| Wong, V | 1 |
| Scharf, C | 1 |
| Oechslin, EN | 1 |
| Salomon, F | 1 |
| Kiowski, W | 1 |
| Reynolds, NJ | 1 |
| Jones, SK | 1 |
| Crossley, J | 1 |
| Harman, RR | 1 |
| Clouston, PD | 1 |
| Donnelly, PE | 1 |
| Costa-Jussà, FR | 1 |
| Guevara, A | 1 |
| Brook, GA | 1 |
| Duchen, LW | 1 |
| Jacobs, JM | 1 |
| Kheĭnonen, IM | 1 |
| Semikhatova, OB | 1 |
| Aretinskiĭ, VV | 1 |
| Mitova, M | 1 |
| Bednarík, B | 1 |
| Lupínek, Z | 1 |
| Cerný, E | 1 |
| Stäubli, M | 1 |
| Zimmermann, A | 1 |
| Bircher, J | 1 |
1 review available for amiodarone and Necrosis
| Article | Year |
|---|---|
[Acute hepatotoxicity from amiodarone].
Topics: Acute Disease; Aged; Amiodarone; Chemical and Drug Induced Liver Injury; Humans; Liver; Male; Necros | 1995 |
21 other studies available for amiodarone and Necrosis
| Article | Year |
|---|---|
Hyaluronidase for Skin Necrosis Induced by Amiodarone.
Topics: Amiodarone; Humans; Hyaluronoglucosaminidase; Necrosis; Skin Abnormalities | 2022 |
Hyaluronidase for Skin Necrosis Induced by Amiodarone.
Topics: Amiodarone; Humans; Hyaluronoglucosaminidase; Necrosis; Skin Abnormalities | 2022 |
Hyaluronidase for Skin Necrosis Induced by Amiodarone.
Topics: Amiodarone; Humans; Hyaluronoglucosaminidase; Necrosis; Skin Abnormalities | 2022 |
Hyaluronidase for Skin Necrosis Induced by Amiodarone.
Topics: Amiodarone; Humans; Hyaluronoglucosaminidase; Necrosis; Skin Abnormalities | 2022 |
[Skin necrosis and consequences of accidental subcutaneous administration of amiodarone].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Eruptions; Hand; Humans; Male; Necrosis; Skin | 2015 |
Mechanisms of amiodarone and desethylamiodarone cytotoxicity in nontransformed human peripheral lung epithelial cells.
Topics: Amiodarone; Angiotensin II; Angiotensinogen; Anti-Arrhythmia Agents; Apoptosis; Cell Survival; Cells | 2011 |
Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Analgesics, Non-Narcotic; Ani | 2002 |
Mechanisms of benzarone and benzbromarone-induced hepatic toxicity.
Topics: Amiodarone; Animals; Apoptosis; Benzbromarone; Benzofurans; Cell Line, Tumor; Hepatocytes; Ketone Bo | 2005 |
A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death.
Topics: Amiodarone; Animals; Apoptosis; Cytochromes c; Humans; Ischemia; Jurkat Cells; Magnetic Resonance Sp | 2006 |
Hepatocellular toxicity and pharmacological effect of amiodarone and amiodarone derivatives.
Topics: Adenosine Triphosphate; Amiodarone; Animals; Annexin A5; Anti-Arrhythmia Agents; Apoptosis; Cell Lin | 2006 |
Amiodarone induced skin necrosis.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Eruptions; Humans; Male; Middle Aged; | 2006 |
Colon ischaemia and necrosis as a complication of prolonged but successful CPR.
Topics: Adrenergic Agonists; Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Colec | 2006 |
Effects of lorcainide and amiodarone on stress-induced myocardial damage in the rat.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Benzofurans; Cardiomyopathies; Femal | 1984 |
Acute necrotizing pneumonitis and hyperglycemia after amiodarone therapy. Case report and review of amiodarone-associated pulmonary disease.
Topics: Acute Disease; Aged; Amiodarone; Benzofurans; Humans; Hyperglycemia; Lung; Male; Necrosis; Pneumonia | 1984 |
Amiodarone induces a different pattern of ultrastructural change in the thyroid to iodine excess alone in both the BB/W rat and the Wistar rat.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Apoptosis; Cell Nucleus; Endoplasmic Reticulum; Inclusi | 1997 |
[Comparative evaluation of the effect of dimebon, obzidan, finoptin, and cordarone on the functional state of the ischemic focus and the size of necrosis zone during experimental myocardial infarction].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cats; Histamine H1 Antagonists; Indoles; Myocardial Inf | 1996 |
In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract.
Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Animals; Antioxidants; Apopto | 2000 |
Clinical picture: Amiodarone-induced pulmonary mass and cutaneous vasculitis.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Lung Diseases; Male; Necrosis; Vasculitis, Leukocy | 2001 |
Methotrexate induced skin necrosis: a drug interaction with amiodarone?
Topics: Aged; Amiodarone; Drug Interactions; Female; Humans; Methotrexate; Necrosis; Skin | 1989 |
Acute necrotising myopathy associated with amiodarone therapy.
Topics: Acute Disease; Aged; Aged, 80 and over; Amiodarone; Humans; Hypothyroidism; Male; Muscles; Muscular | 1989 |
Changes in denervated skeletal muscle of amiodarone-fed mice.
Topics: Amiodarone; Animals; Mice; Mice, Inbred BALB C; Microscopy, Electron; Muscle Denervation; Muscles; N | 1988 |
[Effect of cordarone on the size of the lesion in patients with acute myocardial infarction].
Topics: Acute Disease; Adult; Aged; Amiodarone; Blood Pressure; Creatine Kinase; Electrocardiography; Humans | 1987 |
The effect of cordarone on isoproterenol-induced damage to the myocardium in rats.
Topics: Amiodarone; Animals; Benzofurans; Cardiomyopathies; Isoproterenol; Male; Necrosis; Rats; Rats, Inbre | 1986 |
Amiodarone-induced vasculitis and polyserositis.
Topics: Adult; Amiodarone; Benzofurans; Humans; Male; Necrosis; Photosensitivity Disorders; Serositis; Tachy | 1985 |