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amiodarone and Multiple Organ Failure

amiodarone has been researched along with Multiple Organ Failure in 12 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Multiple Organ Failure: A progressive condition usually characterized by combined failure of several organs such as the lungs, liver, kidney, along with some clotting mechanisms, usually postinjury or postoperative.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone was stopped, and the patient was treated with steroids, which improved his symptoms and organ dysfunctions."5.56Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis. ( Ijaz, M; Jasti, Y; Khan, A; Kugasia, IR, 2020)
"A 77-year-old female patient with symptomatic atrial fibrillation with fast ventricular rate despite conventional antiarrhythmic therapy was treated with dronedarone."3.81Toxic Epidermal Necrolysis During Dronedarone Treatment: First Report of a Severe Serious Adverse Event Of A New Antiarrhythmic Drug. ( Figulla, HR; Franz, M; Gecks, T; Jung, C; Kühnert, H; Prochnau, D; Schliemann, S, 2015)
"Amiodarone was stopped, and the patient was treated with steroids, which improved his symptoms and organ dysfunctions."1.56Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis. ( Ijaz, M; Jasti, Y; Khan, A; Kugasia, IR, 2020)
"Dronedarone is a benzofuran derivative resembling amiodarone that was intended to reduce the iodine-associated tissue deposition and organ toxicity seen with the latter."1.43The use of dronedarone for recurrent ventricular tachycardia: a case report and review of the literature. ( Brent Mitchell, L; Kuriachan, V; Rizkallah, J, 2016)
"In the current epidemic of Ebola virus disease in western Africa, many aid workers have become infected."1.42Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care. ( Becker, S; Brodt, HR; de Leuw, P; Grünewald, T; Kann, G; Kempf, VA; Keppler, OT; Stephan, C; Vogl, T; Wolf, T; Zacharowski, K, 2015)
"Based on this case amiodarone-related pneumonitis will be discussed, which due to a lack of pathognomonic symptoms is often difficult to diagnose and for which there are few treatment options available."1.35[Amiodarone-induced pneumonitis. Lethal complication in a patient after thoracic surgery]. ( Fisseler-Eckhoff, A; Ghezel-Ahmadi, V; Kürschner, VC; Obenhaus, T; Schirren, J; Schmitz, JE, 2008)
"We report a case of a patient with paroxysmal atrial fibrillation (PAF) and with a permanent AAIR (bipolar atrial-inhibited adaptive rate) pacemaker who suffered life-threatening episodes of arrhythmias during operation."1.33Anesthetic management of an AAI pacemaker patient with paroxysmal atrial fibrillation during colorectal surgery. ( Borel, CO; Lin, JA; Wang, WB; Wong, CS; Wu, CT; Yang, CP; Yeh, CC, 2006)
" Amiodarone infusion (mean dosage 24 h: 1625+/-528 mg; 48 h: 2708+/-895 mg) restored sinus rhythm in 54% of study patients within 12 h, in 64% within 24 h, and in 75% within 48 h."1.32High-dosage continuous amiodarone therapy to treat new-onset supraventricular tachyarrhythmias in surgical intensive care patients: an observational study. ( Dünser, MW; Friesenecker, B; Hasibeder, WR; Knotzer, H; Mayr, AJ; Pajk, W; Ritsch, N; Ulmer, H; Wenzel, V, 2004)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19901 (8.33)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's4 (33.33)24.3611
2020's1 (8.33)2.80

Authors

AuthorsStudies
Kugasia, IR1
Ijaz, M1
Khan, A1
Jasti, Y1
Kaese, S1
Schülke, C1
Lebiedz, P1
Wolf, T1
Kann, G1
Becker, S1
Stephan, C1
Brodt, HR1
de Leuw, P1
Grünewald, T1
Vogl, T1
Kempf, VA1
Keppler, OT1
Zacharowski, K1
Gecks, T1
Prochnau, D1
Franz, M1
Jung, C1
Kühnert, H1
Schliemann, S1
Figulla, HR1
Rizkallah, J1
Kuriachan, V1
Brent Mitchell, L1
Ghezel-Ahmadi, V1
Kürschner, VC1
Fisseler-Eckhoff, A1
Schirren, J1
Schmitz, JE1
Obenhaus, T1
MacFadyen, RJ1
Palmer, TJ1
Hisamuddin, K1
Celik, SK1
Cevik, A1
Buket, S1
Charchaflieh, J1
O'Connor, MF1
Mayr, AJ1
Dünser, MW1
Ritsch, N1
Pajk, W1
Friesenecker, B1
Knotzer, H1
Ulmer, H1
Wenzel, V1
Hasibeder, WR1
Lin, JA1
Borel, CO1
Wang, WB1
Wong, CS1
Yeh, CC1
Yang, CP1
Wu, CT1
Delbanco, T1
Hartman, EE1
Holt, AW1

Other Studies

12 other studies available for amiodarone and Multiple Organ Failure

ArticleYear
Amiodarone Toxicity Presenting with Acute Onset of Systemic Inflammatory Response Syndrome and Multiorgan Failure Mimicking Sepsis.
    The American journal of case reports, 2020, Oct-23, Volume: 21

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Multiple Organ Failure; Sepsis; Systemic Inf

2020
Thyrotoxic cardiomyopathy with recurrent ventricular fibrillation and multi-organ failure.
    Intensive care medicine, 2014, Volume: 40, Issue:10

    Topics: Amiodarone; Anti-Arrhythmia Agents; Antithyroid Agents; Cardiomyopathies; Cardiopulmonary Resuscitat

2014
Severe Ebola virus disease with vascular leakage and multiorgan failure: treatment of a patient in intensive care.
    Lancet (London, England), 2015, Apr-11, Volume: 385, Issue:9976

    Topics: Adult; Amides; Amiodarone; Anti-Infective Agents; Antiviral Agents; Blood Vessels; Critical Care; Fi

2015
Toxic Epidermal Necrolysis During Dronedarone Treatment: First Report of a Severe Serious Adverse Event Of A New Antiarrhythmic Drug.
    Cardiovascular toxicology, 2015, Volume: 15, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biopsy; Dronedarone; Fatal Outcome; F

2015
The use of dronedarone for recurrent ventricular tachycardia: a case report and review of the literature.
    BMC research notes, 2016, Jul-27, Volume: 9

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Catheter Ablation; Dronedarone; Fatal Outcome

2016
[Amiodarone-induced pneumonitis. Lethal complication in a patient after thoracic surgery].
    Der Anaesthesist, 2008, Volume: 57, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Non-Small-Cell Lung; Diagnosis, Differential; F

2008
Rapidly fatal acute amiodarone hepatitis occurring in the context of multiple organ failure.
    International journal of cardiology, 2003, Volume: 91, Issue:2-3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathy, Dilated; Chemical and Drug

2003
Case 3--2004: acute multisystem organ failure in the immediate postoperative period after routine CABG surgery.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Bypass; Humans; Male; Middle Aged; Multiple Orga

2004
High-dosage continuous amiodarone therapy to treat new-onset supraventricular tachyarrhythmias in surgical intensive care patients: an observational study.
    Wiener klinische Wochenschrift, 2004, May-31, Volume: 116, Issue:9-10

    Topics: Acid-Base Equilibrium; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Bilirubin; Creat

2004
Anesthetic management of an AAI pacemaker patient with paroxysmal atrial fibrillation during colorectal surgery.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:5

    Topics: Aged; Amiodarone; Anesthesia, General; Anti-Arrhythmia Agents; Atrial Fibrillation; Atropine; Bradyc

2006
A 75-year-old man with congestive heart failure, 1 year later.
    JAMA, 2000, Feb-23, Volume: 283, Issue:8

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Delivery of Health Care; Empathy; Heart Failure; Humans; I

2000
Hemodynamic responses to amiodarone in critically ill patients receiving catecholamine infusions.
    Critical care medicine, 1989, Volume: 17, Issue:12

    Topics: Aged; Aged, 80 and over; Amiodarone; Cardiac Output; Catecholamines; Digoxin; Drug Synergism; Heart

1989