amiodarone has been researched along with Malaria in 5 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Malaria: A protozoan disease caused in humans by four species of the PLASMODIUM genus: PLASMODIUM FALCIPARUM; PLASMODIUM VIVAX; PLASMODIUM OVALE; and PLASMODIUM MALARIAE; and transmitted by the bite of an infected female mosquito of the genus ANOPHELES. Malaria is endemic in parts of Asia, Africa, Central and South America, Oceania, and certain Caribbean islands. It is characterized by extreme exhaustion associated with paroxysms of high FEVER; SWEATING; shaking CHILLS; and ANEMIA. Malaria in ANIMALS is caused by other species of plasmodia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the first systematic study of antimalarial 1,2,4-trioxolanes bearing a substitution pattern regioisomeric to that of arterolane." | 7.85 | Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane. ( Blank, BR; Gut, J; Renslo, AR; Rosenthal, PJ, 2017) |
| "Amodiaquine was not found in any sample, but the major metabolite monodesethylamodiaquine was detected and was assumed to be the sole derivative that contributed significantly to antimalarial activity in the blood." | 5.27 | Disposition of monodesethylamodiaquine after a single oral dose of amodiaquine and three regimens for prophylaxis against Plasmodium falciparum malaria. ( Blayo, MC; Faurisson, F; Le Bras, J; Pussard, E; Scherrmann, JM; Verdier, F, 1987) |
| "We describe the first systematic study of antimalarial 1,2,4-trioxolanes bearing a substitution pattern regioisomeric to that of arterolane." | 3.85 | Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane. ( Blank, BR; Gut, J; Renslo, AR; Rosenthal, PJ, 2017) |
| "Oral amiodarone was continued and there was no recurrence of tachycardia." | 1.39 | Malaria and the conducting system of the heart. ( Alva, J; Bhat, S; Kumar, M, 2013) |
| "Amodiaquine was not found in any sample, but the major metabolite monodesethylamodiaquine was detected and was assumed to be the sole derivative that contributed significantly to antimalarial activity in the blood." | 1.27 | Disposition of monodesethylamodiaquine after a single oral dose of amodiaquine and three regimens for prophylaxis against Plasmodium falciparum malaria. ( Blayo, MC; Faurisson, F; Le Bras, J; Pussard, E; Scherrmann, JM; Verdier, F, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (80.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Blank, BR | 1 |
| Gut, J | 1 |
| Rosenthal, PJ | 1 |
| Renslo, AR | 1 |
| Antonova-Koch, Y | 1 |
| Meister, S | 1 |
| Abraham, M | 1 |
| Luth, MR | 1 |
| Ottilie, S | 1 |
| Lukens, AK | 1 |
| Sakata-Kato, T | 1 |
| Vanaerschot, M | 1 |
| Owen, E | 1 |
| Jado, JC | 1 |
| Maher, SP | 1 |
| Calla, J | 1 |
| Plouffe, D | 1 |
| Zhong, Y | 1 |
| Chen, K | 1 |
| Chaumeau, V | 1 |
| Conway, AJ | 1 |
| McNamara, CW | 1 |
| Ibanez, M | 1 |
| Gagaring, K | 1 |
| Serrano, FN | 1 |
| Eribez, K | 1 |
| Taggard, CM | 1 |
| Cheung, AL | 1 |
| Lincoln, C | 1 |
| Ambachew, B | 1 |
| Rouillier, M | 1 |
| Siegel, D | 1 |
| Nosten, F | 1 |
| Kyle, DE | 1 |
| Gamo, FJ | 1 |
| Zhou, Y | 1 |
| Llinás, M | 1 |
| Fidock, DA | 1 |
| Wirth, DF | 1 |
| Burrows, J | 1 |
| Campo, B | 1 |
| Winzeler, EA | 1 |
| Bobbala, D | 1 |
| Alesutan, I | 1 |
| Föller, M | 1 |
| Tschan, S | 1 |
| Huber, SM | 1 |
| Lang, F | 1 |
| Bhat, S | 1 |
| Kumar, M | 1 |
| Alva, J | 1 |
| Pussard, E | 1 |
| Verdier, F | 1 |
| Faurisson, F | 1 |
| Scherrmann, JM | 1 |
| Le Bras, J | 1 |
| Blayo, MC | 1 |
5 other studies available for amiodarone and Malaria
| Article | Year |
|---|---|
Enantioselective Synthesis and in Vivo Evaluation of Regioisomeric Analogues of the Antimalarial Arterolane.
Topics: Animals; Antimalarials; Female; Ferrous Compounds; Heterocyclic Compounds, 1-Ring; Malaria; Mice; Pe | 2017 |
Open-source discovery of chemical leads for next-generation chemoprotective antimalarials.
Topics: Antimalarials; Chemoprevention; Drug Discovery; Drug Evaluation, Preclinical; Humans; Malaria; Mitoc | 2018 |
Protective effect of amiodarone in malaria.
Topics: Amiodarone; Animals; Apoptosis; Enzyme Inhibitors; Erythrocytes; Female; Humans; Malaria; Male; Mice | 2010 |
Malaria and the conducting system of the heart.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Heart Conduction System; Humans; Mal | 2013 |
Disposition of monodesethylamodiaquine after a single oral dose of amodiaquine and three regimens for prophylaxis against Plasmodium falciparum malaria.
Topics: Adult; Amiodarone; Amodiaquine; Animals; Female; Half-Life; Humans; Malaria; Male; Middle Aged; Plas | 1987 |