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amiodarone and Macular Degeneration

amiodarone has been researched along with Macular Degeneration in 4 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Macular Degeneration: Degenerative changes in the RETINA usually of older adults which results in a loss of vision in the center of the visual field (the MACULA LUTEA) because of damage to the retina. It occurs in dry and wet forms.

Research Excerpts

ExcerptRelevanceReference
"Thyroid disorders and eye diseases are interrelated through several mechanisms thus, awareness of this relation has a great impact on early diagnosis and treatment."5.05Thyroid and Eye: Where They Meet in Clinical Practice. ( El-Eshmawy, MM; Shahin, M, 2020)
" The dose-response curves of these four compounds are indicative of multiple binding sites and/or modes of interaction with ABCR."1.30Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease. ( Molday, RS; Nathans, J; Sun, H, 1999)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's2 (50.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
El-Eshmawy, MM1
Shahin, M1
Pelletier, AL1
Thomas, J1
Shaw, FR1
Bratulescu, M1
Zemba, M1
Gheorghieva, V1
Andrei, S1
Cucu, B1
Dobrescu, N1
Sun, H1
Molday, RS1
Nathans, J1

Reviews

1 review available for amiodarone and Macular Degeneration

ArticleYear
Thyroid and Eye: Where They Meet in Clinical Practice.
    Endocrine, metabolic & immune disorders drug targets, 2020, Volume: 20, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antithyroid Agents; Diabetic Retinopathy; Eye; Eye Dise

2020

Other Studies

3 other studies available for amiodarone and Macular Degeneration

ArticleYear
Vision loss in older persons.
    American family physician, 2009, Jun-01, Volume: 79, Issue:11

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Asthmatic Agents; Blindness; Cataract; Causality; Comorbid

2009
[Ocular manifestation in amiodarone toxicity--case report].
    Oftalmologia (Bucharest, Romania : 1990), 2005, Volume: 49, Issue:4

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chorioretinitis; Female

2005
Retinal stimulates ATP hydrolysis by purified and reconstituted ABCR, the photoreceptor-specific ATP-binding cassette transporter responsible for Stargardt disease.
    The Journal of biological chemistry, 1999, Mar-19, Volume: 274, Issue:12

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amiodarone; Animals; ATP-Binding Cassette Transpo

1999