amiodarone has been researched along with Lysosomal Enzyme Disorders in 4 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phospholipidosis (PLD) is a lysosomal storage disorder induced by compounds, notably cationic amphiphilic drugs, which although reversible interferes with cellular phospholipids." | 1.38 | In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets. ( Atzpodien, EA; Csato, M; Doessegger, L; Fischer, H; Lenz, B; Schmitt, G; Singer, T, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fischer, H | 1 |
| Atzpodien, EA | 1 |
| Csato, M | 1 |
| Doessegger, L | 1 |
| Lenz, B | 1 |
| Schmitt, G | 1 |
| Singer, T | 1 |
| Öhlinger, K | 1 |
| Absenger-Novak, M | 1 |
| Meindl, C | 1 |
| Ober, J | 1 |
| Fröhlich, E | 1 |
| Pedro, L | 1 |
| Rudewicz, PJ | 1 |
| Amacher, DE | 1 |
| Chalasani, N | 1 |
1 review available for amiodarone and Lysosomal Enzyme Disorders
| Article | Year |
|---|---|
Drug-induced hepatic steatosis.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Anti-Retroviral Agents; Anticholesteremic Agents; Antic | 2014 |
3 other studies available for amiodarone and Lysosomal Enzyme Disorders
| Article | Year |
|---|---|
In silico assay for assessing phospholipidosis potential of small druglike molecules: training, validation, and refinement using several data sets.
Topics: Animals; Cattle; Cells, Cultured; Computer Simulation; Cornea; Drug-Related Side Effects and Adverse | 2012 |
Different Sensitivity of Macrophages to Phospholipidosis Induction by Amphiphilic Cationic Drugs.
Topics: Amiodarone; Animals; Cations; Cell Line; Chloroquine; Humans; Lysosomal Storage Diseases; Macrophage | 2020 |
Analysis of Live Single Cells by Confocal Microscopy and High-Resolution Mass Spectrometry to Study Drug Uptake, Metabolism, and Drug-Induced Phospholipidosis.
Topics: Amiodarone; Hep G2 Cells; Humans; Lysosomal Storage Diseases; Mass Spectrometry; Microscopy, Confoca | 2020 |