amiodarone has been researched along with Liver Failure, Acute in 11 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To describe a challenging patient case in which dronedarone was selected for a patient with atrial fibrillation and heart failure; the drug may have been associated with worsening heart failure, leading to acute renal and hepatic failure." | 7.76 | Worsening heart failure in the setting of dronedarone initiation. ( Coons, JC; Plauger, KM; Seybert, AL; Sokos, GG, 2010) |
| "Acute hepatic failure is a rare and potentially lethal complication of propylthiouracil (PTU) use for hyperthyroidism." | 7.72 | Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure. ( Arteaga, E; Brusco, F; González, G; Soto, N, 2004) |
| "To describe a challenging patient case in which dronedarone was selected for a patient with atrial fibrillation and heart failure; the drug may have been associated with worsening heart failure, leading to acute renal and hepatic failure." | 3.76 | Worsening heart failure in the setting of dronedarone initiation. ( Coons, JC; Plauger, KM; Seybert, AL; Sokos, GG, 2010) |
| "Acute hepatic failure is a rare and potentially lethal complication of propylthiouracil (PTU) use for hyperthyroidism." | 3.72 | Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure. ( Arteaga, E; Brusco, F; González, G; Soto, N, 2004) |
| "Amiodarone was immediately withheld, and N-acetylcysteine (NAC) was initiated." | 2.58 | Acute liver failure with amiodarone infusion: A case report and systematic review. ( Attar, BM; Demetria, M; Devani, K; Jaiswal, P; Jaiswal, R; Patel, D; Szynkarek, R; Wang, Y; Yap, JE, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (9.09) | 29.6817 |
| 2010's | 9 (81.82) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Balint Ilie, C | 1 |
| Montón Dito, JM | 1 |
| Esteban Molina, A | 1 |
| Jaiswal, P | 1 |
| Attar, BM | 1 |
| Yap, JE | 1 |
| Devani, K | 1 |
| Jaiswal, R | 1 |
| Wang, Y | 1 |
| Szynkarek, R | 1 |
| Patel, D | 1 |
| Demetria, M | 1 |
| Nicot, F | 1 |
| Procopi, N | 1 |
| Nguyen, LS | 1 |
| Li, JG | 1 |
| Yang, TC | 1 |
| Yu, DM | 1 |
| Ren, TH | 1 |
| Coons, JC | 1 |
| Plauger, KM | 1 |
| Seybert, AL | 1 |
| Sokos, GG | 1 |
| Joghetaei, N | 1 |
| Weirich, G | 1 |
| Huber, W | 1 |
| Büchler, P | 1 |
| Estner, H | 1 |
| Akbal, E | 1 |
| Batgi, H | 1 |
| Koçak, E | 1 |
| Canatan, T | 1 |
| Köklü, S | 1 |
| Capucci, A | 1 |
| Guerra, F | 1 |
| Antenucci, C | 1 |
| Antonicelli, R | 1 |
| Bocconcelli, P | 1 |
| Boriani, G | 1 |
| Busacca, P | 1 |
| Ciampani, N | 1 |
| Della Casa, S | 1 |
| Gabrielli, D | 1 |
| Galvani, M | 1 |
| Margheri, M | 1 |
| Melandri, F | 1 |
| Modena, MG | 1 |
| Perna, GP | 1 |
| Pieri, P | 1 |
| Piovaccari, G | 1 |
| Pozzolini, A | 1 |
| Rapezzi, C | 1 |
| Villani, GQ | 1 |
| De Ponti, F | 1 |
| Mugelli, A | 1 |
| Grecian, R | 1 |
| Ainslie, M | 1 |
| Brusco, F | 1 |
| González, G | 1 |
| Soto, N | 1 |
| Arteaga, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias[NCT03413150] | 80 participants (Actual) | Observational | 2007-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for amiodarone and Liver Failure, Acute
| Article | Year |
|---|---|
Acute liver failure with amiodarone infusion: A case report and systematic review.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Hospitalization; Humans; Infusions, Intravenous; L | 2018 |
[Dronedarone: a real innovation or a mere second-best choice? How to find the way among guidelines, regulatory agencies and daily clinical practice].
Topics: Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Heart Rate; Humans | 2012 |
9 other studies available for amiodarone and Liver Failure, Acute
| Article | Year |
|---|---|
[Severe acute hepatic failure secondary to amiodarone overdose].
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiovascular Agents; Drug-Related Side Effects and Adverse Rea | 2023 |
Intravenous amiodarone-induced acute liver failure in cardiac surgery intensive care unit.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Surgical Procedures; Critical | 2018 |
Fatal acute liver failure after intravenous amiodarone administration.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Fatal Outcome; Female; Humans; | 2015 |
Worsening heart failure in the setting of dronedarone initiation.
Topics: Acute Kidney Injury; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Disease Progression; D | 2010 |
Acute liver failure associated with dronedarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Biopsy; Dronedarone; Female; Humans; | 2011 |
Low-dose amiodarone-induced fatal liver failure.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dose- | 2013 |
[Between guidelines and regulatory decisions: the odyssey of dronedarone].
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Drug and Narcotic Control; Evi | 2012 |
Acute hepatic failure following intravenous amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Infusions, Intravenous; Liver Failure, Acute; Male | 2012 |
Successful treatment of hyperthyroidism with amiodarone in a patient with propylthiouracil-induced acute hepatic failure.
Topics: Adult; Amiodarone; Female; Humans; Hyperthyroidism; Liver Failure, Acute; Propylthiouracil; Triiodot | 2004 |