amiodarone has been researched along with Liver Diseases in 22 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Liver Diseases: Pathological processes of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone may still be safely prescribed for Chinese patients who have baseline liver dysfunction." | 7.73 | Prevalence of amiodarone-related hepatotoxicity in 720 Chinese patients with or without baseline liver dysfunction. ( Chan, WW; Fung, JW; Ho, SS; Hui, HH; Kum, LC; Sanderson, JE; Wong, GW; Yu, CM, 2006) |
| "Amiodarone may still be safely prescribed for Chinese patients who have baseline liver dysfunction." | 3.73 | Prevalence of amiodarone-related hepatotoxicity in 720 Chinese patients with or without baseline liver dysfunction. ( Chan, WW; Fung, JW; Ho, SS; Hui, HH; Kum, LC; Sanderson, JE; Wong, GW; Yu, CM, 2006) |
| "Amiodarone treatment increased significantly the liver-conjugated diene (P<0." | 1.32 | Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats. ( Agoston, M; Blázovics, A; Fehér, E; Fehér, J; Hagymási, K; Orosz, Z; Orsi, F; Vereckei, A, 2003) |
| " Also, no difference in efficacy of either drug was observed and changes in dosing of digoxin were not required." | 1.27 | Drug interaction studies and encainide use in renal and hepatic impairment. ( Gallo, DG; Quart, BD; Sami, MH; Wood, AJ, 1986) |
| " Daily dosage was 200 mg in 2 cases, 400 mg then 200 mg in the third one, and duration of therapy ranged between 36 and 60 months." | 1.27 | Chronic liver disease after low daily doses of amiodarone. Report of three cases. ( Babany, G; Carcone, B; Dhumeaux, D; Mallat, A; Saint-Marc Girardin, MF; Zafrani, ES, 1986) |
| " These findings suggest that both toxic and hypersensitivity liver injury can occur in response to amiodarone." | 1.27 | Amiodarone hepatotoxicity. A clinicopathologic study of five patients. ( Barwick, KW; Batsford, WP; Enriquez, R; Helzberg, J; Josephson, ME; Riely, CA; Rigas, B; Rosenfeld, LE, 1986) |
| "Amiodarone is a cardiac antiarrhythmic agent now undergoing clinical trials in the United States." | 1.27 | Dense liver in a 72-year-old woman with congestive heart failure. ( Duncan-Myers, J; Jones, WP; Shin, MS; Stanley, RJ, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (36.36) | 18.7374 |
| 1990's | 4 (18.18) | 18.2507 |
| 2000's | 6 (27.27) | 29.6817 |
| 2010's | 1 (4.55) | 24.3611 |
| 2020's | 3 (13.64) | 2.80 |
| Authors | Studies |
|---|---|
| Laukamp, KR | 1 |
| Lennartz, S | 1 |
| Hashmi, A | 1 |
| Obmann, M | 1 |
| Ho, V | 1 |
| Große Hokamp, N | 1 |
| Graner, FP | 1 |
| Gilkeson, R | 1 |
| Persigehl, T | 1 |
| Gupta, A | 1 |
| Ramaiya, N | 1 |
| Sileno, S | 1 |
| Chirila, RM | 1 |
| Harris, DM | 1 |
| Hubel, E | 1 |
| Fishman, S | 1 |
| Holopainen, M | 1 |
| Käkelä, R | 1 |
| Shaffer, O | 1 |
| Houri, I | 1 |
| Zvibel, I | 1 |
| Shibolet, O | 1 |
| Lin, CW | 1 |
| Chen, YS | 1 |
| Lin, CC | 1 |
| Chen, YJ | 1 |
| Lo, GH | 1 |
| Lee, PH | 1 |
| Kuo, PL | 1 |
| Dai, CY | 1 |
| Huang, JF | 1 |
| Chung, WL | 1 |
| Yu, ML | 1 |
| Dahl, P | 1 |
| Danzi, S | 1 |
| Klein, I | 1 |
| Llanos, L | 1 |
| Moreu, R | 1 |
| Peiró, AM | 1 |
| Pascual, S | 1 |
| Francés, R | 1 |
| Such, J | 1 |
| Horga, JF | 1 |
| Pérez-Mateo, M | 1 |
| Zapater, P | 1 |
| Agoston, M | 1 |
| Orsi, F | 1 |
| Fehér, E | 1 |
| Hagymási, K | 1 |
| Orosz, Z | 1 |
| Blázovics, A | 1 |
| Fehér, J | 1 |
| Vereckei, A | 1 |
| Pollak, PT | 2 |
| Shafer, SL | 1 |
| Kum, LC | 1 |
| Chan, WW | 1 |
| Hui, HH | 1 |
| Wong, GW | 1 |
| Ho, SS | 1 |
| Sanderson, JE | 1 |
| Yu, CM | 1 |
| Fung, JW | 1 |
| Collins, AM | 1 |
| Winter, DC | 1 |
| McCormick, AP | 1 |
| Cottell, DC | 1 |
| Geoghegan, JG | 1 |
| Poucell, S | 1 |
| Ireton, J | 1 |
| Valencia-Mayoral, P | 1 |
| Downar, E | 1 |
| Larratt, L | 1 |
| Patterson, J | 1 |
| Blendis, L | 1 |
| Phillips, MJ | 1 |
| Simon, JB | 1 |
| Manley, PN | 1 |
| Brien, JF | 1 |
| Armstrong, PW | 1 |
| Wartofsky, L | 1 |
| Burman, KD | 1 |
| Heuck, A | 1 |
| Mattke, S | 1 |
| Seemann, M | 1 |
| Müller, D | 1 |
| Beuers, U | 1 |
| Huber, A | 1 |
| Reiser, M | 1 |
| Cole, TJ | 1 |
| Proto, AV | 1 |
| Sharma, AD | 1 |
| Carruthers, SG | 1 |
| Lewis, JH | 1 |
| Mullick, F | 1 |
| Ishak, KG | 1 |
| Ranard, RC | 1 |
| Ragsdale, B | 1 |
| Perse, RM | 1 |
| Rusnock, EJ | 1 |
| Wolke, A | 1 |
| Benjamin, SB | 1 |
| Seeff, LB | 1 |
| Quart, BD | 1 |
| Gallo, DG | 1 |
| Sami, MH | 1 |
| Wood, AJ | 1 |
| Shepherd, NA | 1 |
| Dawson, AM | 1 |
| Crocker, PR | 1 |
| Levison, DA | 1 |
| Babany, G | 1 |
| Mallat, A | 1 |
| Zafrani, ES | 1 |
| Saint-Marc Girardin, MF | 1 |
| Carcone, B | 1 |
| Dhumeaux, D | 1 |
| Rigas, B | 1 |
| Rosenfeld, LE | 1 |
| Barwick, KW | 1 |
| Enriquez, R | 1 |
| Helzberg, J | 1 |
| Batsford, WP | 1 |
| Josephson, ME | 1 |
| Riely, CA | 1 |
| Jones, WP | 1 |
| Shin, MS | 1 |
| Stanley, RJ | 1 |
| Duncan-Myers, J | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Multi-center, Open Label, Randomised Parallel- Group Study to Compare the Efficacy of Cholestyramine Plus Standard Treatment Versus Prednisolone Plus Standard Treatment Versus Standard Treatment Alone in Treatment of Overt Hyperthyroidism[NCT03303053] | Phase 3 | 135 participants (Anticipated) | Interventional | 2017-05-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 reviews available for amiodarone and Liver Diseases
| Article | Year |
|---|---|
Use of statins, amiodarone, direct oral anticoagulants and NSAIDs in chronic liver disease: a guide for general clinicians.
Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; A | 2020 |
Thyrotoxic cardiac disease.
Topics: Adrenergic Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Di | 2008 |
Alterations in thyroid function in patients with systemic illness: the "euthyroid sick syndrome".
Topics: Adult; Age Factors; Aged; Amiodarone; Animals; Anorexia Nervosa; Contrast Media; Diabetes Mellitus; | 1982 |
Histopathologic analysis of suspected amiodarone hepatotoxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Chemical and Drug Induced Liver Injury; Diag | 1990 |
18 other studies available for amiodarone and Liver Diseases
| Article | Year |
|---|---|
Iodine accumulation of the liver in patients treated with amiodarone can be unmasked using material decomposition from multiphase spectral-detector CT.
Topics: Aged; Aged, 80 and over; Amiodarone; Computed Tomography Angiography; Fatty Liver; Female; Humans; I | 2020 |
Repetitive amiodarone administration causes liver damage via adipose tissue ER stress-dependent lipolysis, leading to hepatotoxic free fatty acid accumulation.
Topics: Adipocytes; Adipose Tissue; Amiodarone; Animals; Endoplasmic Reticulum Stress; Fatty Acid-Binding Pr | 2021 |
Amiodarone as an autophagy promoter reduces liver injury and enhances liver regeneration and survival in mice after partial hepatectomy.
Topics: Amiodarone; Animals; Autophagy; Autophagy-Related Protein 7; Chloroquine; Disease Models, Animal; He | 2015 |
Causality assessment of liver injury after chronic oral amiodarone intake.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Bayes Theo | 2009 |
Silymarin and vitamin E reduce amiodarone-induced lysosomal phospholipidosis in rats.
Topics: Amiodarone; Animals; Antioxidants; Chemical and Drug Induced Liver Injury; Hepatocytes; Liver Diseas | 2003 |
Use of population modeling to define rational monitoring of amiodarone hepatic effects.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biomarkers; Chemical and Drug Induce | 2004 |
Prevalence of amiodarone-related hepatotoxicity in 720 Chinese patients with or without baseline liver dysfunction.
Topics: Alanine Transaminase; Algorithms; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Fl | 2006 |
Amiodarone hepatotoxicity complicating obstructive jaundice due to ampullary cancer.
Topics: Adenoma; Aged; Amiodarone; Ampulla of Vater; Biopsy; Common Bile Duct Neoplasms; Gallbladder; Humans | 2007 |
Amiodarone-associated phospholipidosis and fibrosis of the liver. Light, immunohistochemical, and electron microscopic studies.
Topics: Amiodarone; Benzofurans; Biopsy; Chemical and Drug Induced Liver Injury; Cholangitis; Female; Humans | 1984 |
Amiodarone hepatotoxicity simulating alcoholic liver disease.
Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chemical and Drug Induced Liver Injury; Diagno | 1984 |
[Increased liver density in computed tomography as a result of anti-arrhythmia therapy with amiodarone].
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Diagnosis, Differential; Fema | 1997 |
[Amiodarone toxicity in a patient with at-risk ventricular arrhythmia].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Chemical and Drug Induced Liver Injury; He | 1997 |
Relation of amiodarone hepatic and pulmonary toxicity to serum drug concentrations and superoxide dismutase activity.
Topics: Alanine Transaminase; Amiodarone; Aspartate Aminotransferases; Chemical and Drug Induced Liver Injur | 1990 |
Drug interaction studies and encainide use in renal and hepatic impairment.
Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anilides; Anti-Arrhythmia Agents; Anticoagulants; An | 1986 |
Granular cells as a marker of early amiodarone hepatotoxicity: a pathological and analytical study.
Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Cytoplasmic Granules; Female; Humans; Iodine; Li | 1987 |
Chronic liver disease after low daily doses of amiodarone. Report of three cases.
Topics: Aged; Aged, 80 and over; Amiodarone; Angina Pectoris; Chemical and Drug Induced Liver Injury; Chroni | 1986 |
Amiodarone hepatotoxicity. A clinicopathologic study of five patients.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Benzofura | 1986 |
Dense liver in a 72-year-old woman with congestive heart failure.
Topics: Aged; Amiodarone; Benzofurans; Chemical and Drug Induced Liver Injury; Female; Heart Failure; Humans | 1985 |