Page last updated: 2024-10-22

amiodarone and Liver Cirrhosis

amiodarone has been researched along with Liver Cirrhosis in 26 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone is an antiarrhythmic drug that has been recognized to induce hepatotoxicity."5.62Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report. ( Ho, CM; Tsai, JH; Wu, IU, 2021)
"We present two cases of liver cirrhosis in patients taking amiodarone."5.35Amiodarone induced liver cirrhosis. Report of two cases. ( Atiq, M; Beland, SS; Davis, JC; Lamps, LW; Rose, JE, 2009)
" Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury."5.33Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: a case report. ( Kotani, K; Maesawa, C; Masuda, T; Oikawa, H; Oikawa, K; Ono, S; Oriso, S; Sato, R; Suzuki, K; Yamada, H; Yashima-Abo, A, 2005)
" Here, we present the HCV treatment challenges facing a patient with HIV coinfection, prior failure of both HIV-1 and HCV therapy, cirrhosis, end-stage renal failure on haemodialysis, as well as management of drug-drug interactions, especially given the need to receive long-term amiodarone therapy."3.88Cure of chronic hepatitis C virus infection in an HIV-coinfected patient with multiple comorbidities and drug interaction challenges. ( Álvarez, H; Bhagani, S; Khoo, S; Llibre, JM; Mariño, A; Schapiro, J; Valcarce, N, 2018)
"We performed a methodological comparison of free triiodothyronine (FT3) estimates in patients with liver cirrhosis and renal failure."3.69Determination of free triiodothyronine by six different methods in patients with non-thyroidal illness and in patients treated with amiodarone. ( Chambron, J; Christofides, N; Gasser, F; Gervais, A; Kaltenbach, G; Petitjean, P; Roul, G; Sapin, R; Schlienger, JL, 1995)
"Amiodarone is an antiarrhythmic drug that has been recognized to induce hepatotoxicity."1.62Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report. ( Ho, CM; Tsai, JH; Wu, IU, 2021)
"Amiodarone is a highly effective treatment for supraventricular and ventricular tachyarrhythmia; however, it could be associated with several serious adverse effects, including liver injury."1.48Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports. ( Hayashi, K; Kawashiri, MA; Kurose, N; Nishida, N; Oyama, T; Sakata, K; Sasaki, M; Sawada, T; Tada, H; Tanaka, Y; Tsuda, T; Yamagishi, M; Yoshida, T, 2018)
"We present two cases of liver cirrhosis in patients taking amiodarone."1.35Amiodarone induced liver cirrhosis. Report of two cases. ( Atiq, M; Beland, SS; Davis, JC; Lamps, LW; Rose, JE, 2009)
"Amiodarone is a lipophilic drug that concentrates in the liver and usually, over a period of time, leads to toxicity related to drug accumulation."1.35Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use. ( Chang, C; Fiel, MI; Raja, K; Thung, SN, 2009)
"Amiodarone chlorhydrate is a diiodated benzofuran derivative, and it is used to treat cardiac rhythm abnormalities."1.34Amiodarone-induced hepatitis and polyneuropathy. ( Kang, DY; Kang, HM; Kang, YS; Kim, SH; Lee, BS; Lee, HY; Seong, JK, 2007)
" Long-term administration of daily low doses of AD carries the risk of progression to irreversible liver injury."1.33Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: a case report. ( Kotani, K; Maesawa, C; Masuda, T; Oikawa, H; Oikawa, K; Ono, S; Oriso, S; Sato, R; Suzuki, K; Yamada, H; Yashima-Abo, A, 2005)
"Amiodarone is an antiarrhythmic drug widely used to treat a variety of supraventricular and ventricular arrhythmias."1.30[Pseudo-alcoholic hepatitis and cirrhosis caused by amiodarone (Cordarone)]. ( Belaiche, J; Lamproye, A; Larrey, D; Ramos, J, 1998)
"The amiodarone was withdrawn."1.27Neuropathy and fatal hepatitis in a patient receiving amiodarone. ( Hole, DW; Lim, PK; Storey, GC; Trewby, PN, 1984)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19906 (23.08)18.7374
1990's7 (26.92)18.2507
2000's8 (30.77)29.6817
2010's3 (11.54)24.3611
2020's2 (7.69)2.80

Authors

AuthorsStudies
Wu, IU1
Tsai, JH1
Ho, CM1
Torimitsu, T1
Yoshida, T2
Nishi, S1
Itoh, H1
Oya, M1
Álvarez, H1
Mariño, A1
Valcarce, N1
Khoo, S1
Bhagani, S1
Schapiro, J1
Llibre, JM1
Tsuda, T1
Tada, H1
Tanaka, Y1
Nishida, N1
Sawada, T1
Sakata, K1
Hayashi, K1
Kawashiri, MA1
Oyama, T1
Sasaki, M1
Kurose, N1
Yamagishi, M1
Hoteit, MA1
Sanchez, W1
Atiq, M1
Davis, JC1
Lamps, LW1
Beland, SS1
Rose, JE1
Raja, K1
Thung, SN2
Fiel, MI1
Chang, C1
Ben Chaabane, N1
Hellara, O1
Safer, L1
Melki, W1
Bdioui, F1
Zakhama, A1
Saffar, H1
Chow, KM1
Liu, ZC1
Oikawa, H1
Maesawa, C1
Sato, R1
Oikawa, K1
Yamada, H1
Oriso, S1
Ono, S1
Yashima-Abo, A1
Kotani, K1
Suzuki, K1
Masuda, T1
Puli, SR1
Fraley, MA1
Puli, V1
Kuperman, AB1
Alpert, MA1
Coban, S1
Köklü, S1
Sencer, H1
Ekiz, F1
Ormeci, N1
Kang, HM1
Kang, YS1
Kim, SH1
Seong, JK1
Kang, DY1
Lee, HY1
Lee, BS1
Lim, PK1
Trewby, PN1
Storey, GC1
Hole, DW1
Reñe, JM1
Buenestado, J1
Pais, B1
Piñol, MC1
Sapin, R1
Schlienger, JL1
Kaltenbach, G1
Gasser, F1
Christofides, N1
Roul, G1
Gervais, A1
Petitjean, P1
Chambron, J1
Snir, Y1
Pick, N1
Riesenberg, K1
Yanai-Inbar, I1
Zirkin, H1
Schlaeffer, F1
Harrison, RF1
Elias, E1
Malaterre, HR1
Renou, C1
Kallee, K1
Gauthier, A1
Lamproye, A1
Ramos, J1
Larrey, D1
Belaiche, J1
Sastri, SV1
Diaz-Arias, AA1
Marshall, JB1
Bach, N1
Schultz, BL1
Cohen, LB1
Squire, A1
Gordon, R1
Schaffner, F1
Adler, M1
Ros, P1
Cremer, M1
Quiriny, M1
Henry, JP1
Lecocq, E1
Rinder, HM1
Love, JC1
Wexler, R1
Tordjman, K1
Katz, I1
Bursztyn, M1
Rosenthal, T1
Babany, G1
Saint-Marc Girardin, MF1
Zafrani, ES1
Coderc, E1
Dhumeaux, D1

Reviews

2 reviews available for amiodarone and Liver Cirrhosis

ArticleYear
[Cirrhosis caused by amiodarone].
    Revista espanola de enfermedades digestivas, 1995, Volume: 87, Issue:5

    Topics: Aged; Amiodarone; Biopsy; Chronic Disease; Female; Humans; Liver; Liver Cirrhosis

1995
[Drug-induced hepatic lesions].
    Revue medicale de Bruxelles, 1986, Volume: 7, Issue:2

    Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocel

1986

Other Studies

24 other studies available for amiodarone and Liver Cirrhosis

ArticleYear
Fatal acute-on-chronic liver failure in amiodarone-related steatohepatitis: a case report.
    BMC gastroenterology, 2021, Feb-02, Volume: 21, Issue:1

    Topics: Acute-On-Chronic Liver Failure; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced

2021
Amiodarone-induced multiple organ damage in an Alström syndrome patient with end-stage renal disease and hepatic cirrhosis.
    CEN case reports, 2022, Volume: 11, Issue:1

    Topics: Alstrom Syndrome; Amiodarone; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Female; Humans; Ki

2022
Cure of chronic hepatitis C virus infection in an HIV-coinfected patient with multiple comorbidities and drug interaction challenges.
    International journal of STD & AIDS, 2018, Volume: 29, Issue:9

    Topics: Amiodarone; Antiviral Agents; Coinfection; Comorbidity; Drug Interactions; Female; Heart Diseases; H

2018
Amiodarone-induced reversible and irreversible hepatotoxicity: two case reports.
    Journal of medical case reports, 2018, Apr-14, Volume: 12, Issue:1

    Topics: Aged; Alanine Transaminase; Amiodarone; Anti-Arrhythmia Agents; Aspartate Aminotransferases; Chemica

2018
A bright liver.
    Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2008, Volume: 6, Issue:9

    Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Bilirubin

2008
Amiodarone induced liver cirrhosis. Report of two cases.
    Journal of gastrointestinal and liver diseases : JGLD, 2009, Volume: 18, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Fatal Outcome; Female; Humans; Liver; Liver Cirrhosis; Mal

2009
Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use.
    Seminars in liver disease, 2009, Volume: 29, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Chemical and Drug Induced Liver Injury; Diagnosis,

2009
Cirrhosis with increased density of the liver: amiodarone-induced hepatotoxicity.
    La Tunisie medicale, 2012, Volume: 90, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Female; Humans; Li

2012
Amiodarone and cirrhosis.
    Age and ageing, 2004, Volume: 33, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Dose-Response Relationship, Drug; Human

2004
Liver cirrhosis induced by long-term administration of a daily low dose of amiodarone: a case report.
    World journal of gastroenterology, 2005, Sep-14, Volume: 11, Issue:34

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Humans; Liver Cirrhosis; Male; Myocardi

2005
Hepatic cirrhosis caused by low-dose oral amiodarone therapy.
    The American journal of the medical sciences, 2005, Volume: 330, Issue:5

    Topics: Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Humans; Liver; Liver Cirrhosis

2005
Low dose amiodarone associated cirrhosis.
    Journal of gastroenterology and hepatology, 2007, Volume: 22, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Humans; Liver Cirrhosis; Liver Function

2007
Amiodarone-induced hepatitis and polyneuropathy.
    The Korean journal of internal medicine, 2007, Volume: 22, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Cirr

2007
Neuropathy and fatal hepatitis in a patient receiving amiodarone.
    British medical journal (Clinical research ed.), 1984, Jun-02, Volume: 288, Issue:6431

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Chemical and Drug Induced Liver Injury; Humans;

1984
Determination of free triiodothyronine by six different methods in patients with non-thyroidal illness and in patients treated with amiodarone.
    Annals of clinical biochemistry, 1995, Volume: 32 ( Pt 3)

    Topics: Adult; Aged; Amiodarone; Humans; Immunoassay; Liver Cirrhosis; Middle Aged; Renal Insufficiency; Sen

1995
Fatal hepatic failure due to prolonged amiodarone treatment.
    Journal of clinical gastroenterology, 1995, Volume: 20, Issue:3

    Topics: Amiodarone; Fatal Outcome; Female; Humans; Liver; Liver Cirrhosis; Liver Failure; Middle Aged

1995
Amiodarone-associated cirrhosis with hepatic and lymph node granulomas.
    Histopathology, 1993, Volume: 22, Issue:1

    Topics: Amiodarone; Granuloma; Humans; Liver Cirrhosis; Lymph Nodes; Male; Middle Aged

1993
Akinesia and amiodarone therapy.
    International journal of cardiology, 1997, Volume: 59, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Liver Cirrhosis; Male; Middle Aged;

1997
[Pseudo-alcoholic hepatitis and cirrhosis caused by amiodarone (Cordarone)].
    Revue medicale de Liege, 1998, Volume: 53, Issue:3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Humans; Liver Cirrhosis;

1998
Can pancreatitis be associated with amiodarone hepatotoxicity?
    Journal of clinical gastroenterology, 1990, Volume: 12, Issue:1

    Topics: Aged; Amiodarone; Amylases; Chemical and Drug Induced Liver Injury; Humans; Lipase; Liver Cirrhosis;

1990
Amiodarone hepatotoxicity: progression from steatosis to cirrhosis.
    The Mount Sinai journal of medicine, New York, 1989, Volume: 56, Issue:4

    Topics: Aged; Amiodarone; Biopsy; Fatty Liver; Female; Humans; Liver; Liver Cirrhosis; Liver Function Tests;

1989
Amiodarone hepatotoxicity.
    The New England journal of medicine, 1986, Jan-30, Volume: 314, Issue:5

    Topics: Aged; Amiodarone; Benzofurans; Humans; Liver Cirrhosis; Male; Tachycardia

1986
Amiodarone and the liver.
    Annals of internal medicine, 1985, Volume: 102, Issue:3

    Topics: Aged; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Benzofurans; Female; Humans; Li

1985
[2 cases of cirrhosis in patients treated with amiodarone].
    Gastroenterologie clinique et biologique, 1985, Volume: 9, Issue:3

    Topics: Aged; Amiodarone; Benzofurans; Female; Humans; Liver Cirrhosis; Middle Aged

1985