amiodarone has been researched along with Leishmaniasis in 3 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Leishmaniasis: A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).
| Excerpt | Relevance | Reference |
|---|---|---|
| " Accordingly, amiodarone, an inexpensive and extensively- used class III antiarrhythmic has been proposed as a treatment for Chagas' disease and leishmaniasis." | 8.02 | The Rationale for Use of Amiodarone and its Derivatives for the Treatment of Chagas' Disease and Leishmaniasis. ( Benaim, G; Paniz-Mondolfi, AE; Sordillo, EM, 2021) |
| "The most current treatment against leishmaniasis is chemotherapy." | 6.58 | Emerging role of amiodarone and dronedarone, as antiarrhythmic drugs, in treatment of leishmaniasis. ( Bahrami, S; Bemani, E; Oryan, A, 2018) |
| " Accordingly, amiodarone, an inexpensive and extensively- used class III antiarrhythmic has been proposed as a treatment for Chagas' disease and leishmaniasis." | 4.02 | The Rationale for Use of Amiodarone and its Derivatives for the Treatment of Chagas' Disease and Leishmaniasis. ( Benaim, G; Paniz-Mondolfi, AE; Sordillo, EM, 2021) |
| "The most current treatment against leishmaniasis is chemotherapy." | 2.58 | Emerging role of amiodarone and dronedarone, as antiarrhythmic drugs, in treatment of leishmaniasis. ( Bahrami, S; Bemani, E; Oryan, A, 2018) |
| "Amiodarone is also capable to inhibit the oxidosqualene cyclase, a key enzyme in the synthesis of ergosterol." | 2.47 | Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review. ( Benaim, B; Garcia, CR, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Benaim, G | 1 |
| Paniz-Mondolfi, AE | 1 |
| Sordillo, EM | 1 |
| Oryan, A | 1 |
| Bemani, E | 1 |
| Bahrami, S | 1 |
| Benaim, B | 1 |
| Garcia, CR | 1 |
2 reviews available for amiodarone and Leishmaniasis
| Article | Year |
|---|---|
Emerging role of amiodarone and dronedarone, as antiarrhythmic drugs, in treatment of leishmaniasis.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antiprotozoal Agents; Humans; Leishmania; Leishmaniasis | 2018 |
Targeting calcium homeostasis as the therapy of Chagas' disease and leishmaniasis - a review.
Topics: Amiodarone; Antiprotozoal Agents; Calcium; Chagas Disease; Homeostasis; Humans; Leishmania; Leishman | 2011 |
1 other study available for amiodarone and Leishmaniasis
| Article | Year |
|---|---|
The Rationale for Use of Amiodarone and its Derivatives for the Treatment of Chagas' Disease and Leishmaniasis.
Topics: Amiodarone; Animals; Calcium; Chagas Disease; Dogs; Leishmaniasis; Trypanocidal Agents; Trypanosoma | 2021 |