Page last updated: 2024-10-22

amiodarone and Leishmaniasis, Cutaneous

amiodarone has been researched along with Leishmaniasis, Cutaneous in 4 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Leishmaniasis, Cutaneous: An endemic disease that is characterized by the development of single or multiple localized lesions on exposed areas of skin that typically ulcerate. The disease has been divided into Old and New World forms. Old World leishmaniasis is separated into three distinct types according to epidemiology and clinical manifestations and is caused by species of the L. tropica and L. aethiopica complexes as well as by species of the L. major genus. New World leishmaniasis, also called American leishmaniasis, occurs in South and Central America and is caused by species of the L. mexicana or L. braziliensis complexes.

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (25.00)29.6817
2010's2 (50.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Bemani, E2
Oryan, A2
Bahrami, S2
Anversa, L1
Salles Tiburcio, MG1
Batista, LR1
Cuba, MB1
Nogueira Nascentes, GA1
Martins, TY1
Richini Pereira, VB1
Ruiz, LDS1
Dias da Silva, VJ1
Ramirez, LE1
Serrano-Martín, X1
Payares, G1
De Lucca, M1
Martinez, JC1
Mendoza-León, A1
Benaim, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Efficacy of Intralesional Voriconazole Versus Intralesional Cryotherapy Versus Intralesional Sodium Stibogluconate Versus Oral Doxycycline in the Treatment of Acute Cutaneous Leishmaniasis[NCT05708625]Phase 3136 participants (Anticipated)Interventional2022-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

4 other studies available for amiodarone and Leishmaniasis, Cutaneous

ArticleYear
Effectiveness of amiodarone in treatment of cutaneous leishmaniasis caused by Leishmania major.
    Experimental parasitology, 2019, Volume: 205

    Topics: Adiponectin; Amiodarone; Animals; Anti-Arrhythmia Agents; Antiprotozoal Agents; Cell Line; Female; G

2019
Efficacy of amiodarone and voriconazole combination therapy in cutaneous leishmaniasis in the mice experimentally infected with Leishmania major.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2021, Volume: 27, Issue:7

    Topics: Amiodarone; Animals; Antiprotozoal Agents; Leishmania major; Leishmaniasis, Cutaneous; Mice; Mice, I

2021
Amiodarone and itraconazole improve the activity of pentavalent antimonial in the treatment of experimental cutaneous leishmaniasis.
    International journal of antimicrobial agents, 2017, Volume: 50, Issue:2

    Topics: Amiodarone; Animals; Cricetinae; Disease Models, Animal; Drug Therapy, Combination; Hindlimb; Histoc

2017
Amiodarone and miltefosine act synergistically against Leishmania mexicana and can induce parasitological cure in a murine model of cutaneous leishmaniasis.
    Antimicrobial agents and chemotherapy, 2009, Volume: 53, Issue:12

    Topics: Amiodarone; Animals; Antiprotozoal Agents; Cricetinae; Disease Models, Animal; Drug Synergism; Femal

2009