amiodarone has been researched along with Kidney Failure, Chronic in 17 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 8.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| " Laboratory studies revealed cardiogenic ascites coincided with nephrogenic ascites and subclinical amiodarone-induced hypothyroidism." | 7.78 | Development of refractory ascites during amiodarone therapy in a hemodialysis patient with nephrogenic and cardiogenic ascites. ( Chen, JD; Hwang, B; Lin, YF; Wang, JY, 2012) |
| " After administration of atorvastatin, amiodarone, and fluconazole, rhabdomyolysis developed with electrolyte disturbances (hyperphosphatemia, hyopcalcemia) and a massive increase in creatine kinase and myoglobin." | 7.77 | [Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole]. ( Bruggisser, M; Franz, CC; Krähenbühl, S; Rätz Bravo, AE, 2011) |
| "Here, we report a patient with chronic renal failure who developed EPO-resistant anemia after amiodarone treatment for arrhythmia." | 5.35 | Amiodarone-induced hypothyroidism with EPO-resistant anemia in a patient with chronic renal failure. ( Chang, PM; Ng, YY, 2008) |
| "Poisoning with flecainide acetate is rare and associated with a high mortality." | 4.80 | [Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999) |
| " The study revealed hypothyroidism, iatrogenic due to the use of amiodarone." | 3.96 | An unexpected cause of residual renal function loss. ( Abrantes, C; Assunção, J; Furtado, T; Soares, E; Valério, P; Vaz, AG, 2020) |
| " Here, we present the HCV treatment challenges facing a patient with HIV coinfection, prior failure of both HIV-1 and HCV therapy, cirrhosis, end-stage renal failure on haemodialysis, as well as management of drug-drug interactions, especially given the need to receive long-term amiodarone therapy." | 3.88 | Cure of chronic hepatitis C virus infection in an HIV-coinfected patient with multiple comorbidities and drug interaction challenges. ( Álvarez, H; Bhagani, S; Khoo, S; Llibre, JM; Mariño, A; Schapiro, J; Valcarce, N, 2018) |
| " Laboratory studies revealed cardiogenic ascites coincided with nephrogenic ascites and subclinical amiodarone-induced hypothyroidism." | 3.78 | Development of refractory ascites during amiodarone therapy in a hemodialysis patient with nephrogenic and cardiogenic ascites. ( Chen, JD; Hwang, B; Lin, YF; Wang, JY, 2012) |
| " After administration of atorvastatin, amiodarone, and fluconazole, rhabdomyolysis developed with electrolyte disturbances (hyperphosphatemia, hyopcalcemia) and a massive increase in creatine kinase and myoglobin." | 3.77 | [Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole]. ( Bruggisser, M; Franz, CC; Krähenbühl, S; Rätz Bravo, AE, 2011) |
| " We evaluated the clinical performance of nine FT4 assays in five centres, using a panel of 310 sera: 156 from euthyroid controls; 27 from hyperthyroid patients; 34 from untreated hypothyroidism; 22 from patients with renal failure; 30 from women in the last trimester of pregnancy; 23 from patients on thyroid substitutive therapy; and 18 from patients treated with amiodarone." | 3.72 | Clinical evaluation of nine free thyroxine assays: persistent problems in particular populations. ( Beaudonnet, A; d'Herbomez, M; Forzy, G; Gasser, F; Massart, C; Sapin, R, 2003) |
| "Three labeled-antibody immunoassays of free triiodothyronine (FT3) were studied in hyperthyroid patients, patients with nonthyroidal illness, and patients being treated with amiodarone; we also studied sera presenting known interferences (n for all groups = 465)." | 3.69 | Clinical comparison of three labeled-antibody immunoassays of free triiodothyronine. ( Cosson, E; d'Herbomez, M; Dilouya, A; Dumont, A; Helal, BO; Le Guillouzic, D; Lebtahi, R; Piketty, ML, 1996) |
| "Two patients in chronic renal failure receiving amiodarone for the treatment of refractory arrhythmias were commenced on dialysis, in one case, intermittent peritoneal dialysis, in the other, haemodialysis." | 3.66 | Renal elimination of amiodarone and its desethyl metabolite. ( Harris, L; Hind, CR; Holt, DW; Krikler, SJ; McKenna, WJ; Savage, C; Storey, GC, 1983) |
| "Here, we report a patient with chronic renal failure who developed EPO-resistant anemia after amiodarone treatment for arrhythmia." | 1.35 | Amiodarone-induced hypothyroidism with EPO-resistant anemia in a patient with chronic renal failure. ( Chang, PM; Ng, YY, 2008) |
| "Amiodarone is a very effective antiarrhytmic drug." | 1.34 | Hyperglobulinemia in amiodarone-induced pneumonitis. ( Antipov, N; Farfel, Z; Mayan, H; Mouallem, M; Sela, BA, 2007) |
| " Thus, dosage adjustment in patients with renal impairment is not necessary based on this pharmacokinetic analysis." | 1.29 | Disposition of intravenous amiodarone in subjects with normal and impaired renal function. ( Chow, MS; Izard, M; Klamerus, KJ; Neefe, DL; O'Rangers, E; Ujhelyi, MR; Vadiei, K; Zimmerman, JJ, 1996) |
| " Pharmacokinetic parameters were derived from plasma samples obtained over a 24-h period." | 1.27 | Effect of renal failure or biliary stasis on the pharmacokinetics of amiodarone in the rat. ( Bernhard, R; Ferguson, RK; Fruncillo, RJ; Marchion, C; Swanson, BN, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (23.53) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 3 (17.65) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Soares, E | 1 |
| Valério, P | 1 |
| Abrantes, C | 1 |
| Furtado, T | 1 |
| Assunção, J | 1 |
| Vaz, AG | 1 |
| Torimitsu, T | 1 |
| Yoshida, T | 1 |
| Nishi, S | 1 |
| Itoh, H | 1 |
| Oya, M | 1 |
| Álvarez, H | 1 |
| Mariño, A | 1 |
| Valcarce, N | 1 |
| Khoo, S | 1 |
| Bhagani, S | 1 |
| Schapiro, J | 1 |
| Llibre, JM | 1 |
| Chang, PM | 1 |
| Ng, YY | 1 |
| González Oliva, JC | 1 |
| Saurina i Solé, A | 1 |
| Pou Potau, M | 1 |
| Salas Gama, KR | 1 |
| Ramírez de Arellano Serna, M | 1 |
| Burger, CI | 1 |
| Clase, CM | 1 |
| Gangji, AS | 1 |
| Franz, CC | 1 |
| Bruggisser, M | 1 |
| Krähenbühl, S | 1 |
| Rätz Bravo, AE | 1 |
| Wang, JY | 1 |
| Hwang, B | 1 |
| Lin, YF | 1 |
| Chen, JD | 1 |
| d'Herbomez, M | 2 |
| Forzy, G | 1 |
| Gasser, F | 1 |
| Massart, C | 1 |
| Beaudonnet, A | 1 |
| Sapin, R | 1 |
| Mouallem, M | 1 |
| Antipov, N | 1 |
| Mayan, H | 1 |
| Sela, BA | 1 |
| Farfel, Z | 1 |
| Harris, L | 1 |
| Hind, CR | 1 |
| McKenna, WJ | 1 |
| Savage, C | 1 |
| Krikler, SJ | 1 |
| Storey, GC | 1 |
| Holt, DW | 1 |
| Bonati, M | 1 |
| Galletti, F | 1 |
| Volpi, A | 1 |
| Cumetti, C | 1 |
| Rumolo, R | 1 |
| Bassini, O | 1 |
| Tognoni, G | 1 |
| Piketty, ML | 1 |
| Le Guillouzic, D | 1 |
| Lebtahi, R | 1 |
| Cosson, E | 1 |
| Dumont, A | 1 |
| Dilouya, A | 1 |
| Helal, BO | 1 |
| Ujhelyi, MR | 1 |
| Klamerus, KJ | 1 |
| Vadiei, K | 1 |
| O'Rangers, E | 1 |
| Izard, M | 1 |
| Neefe, DL | 1 |
| Zimmerman, JJ | 1 |
| Chow, MS | 1 |
| Maury, P | 1 |
| Vuille, C | 1 |
| Metzger, J | 1 |
| Veragut, B | 1 |
| Schoenenberger, I | 1 |
| Elamly, A | 1 |
| Chevrolet, JC | 1 |
| Koren, G | 1 |
| Parker, R | 1 |
| Fruncillo, RJ | 1 |
| Swanson, BN | 1 |
| Bernhard, R | 1 |
| Marchion, C | 1 |
| Ferguson, RK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias[NCT03413150] | 80 participants (Actual) | Observational | 2007-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for amiodarone and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Severe flecainide acetate poisoning. Apropos of a case].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate | 1999 |
16 other studies available for amiodarone and Kidney Failure, Chronic
| Article | Year |
|---|---|
An unexpected cause of residual renal function loss.
Topics: Amiodarone; Disease Progression; Glomerular Filtration Rate; Humans; Hypothyroidism; Kidney Failure, | 2020 |
Amiodarone-induced multiple organ damage in an Alström syndrome patient with end-stage renal disease and hepatic cirrhosis.
Topics: Alstrom Syndrome; Amiodarone; Cardiomyopathy, Dilated; Diabetes Mellitus, Type 2; Female; Humans; Ki | 2022 |
Cure of chronic hepatitis C virus infection in an HIV-coinfected patient with multiple comorbidities and drug interaction challenges.
Topics: Amiodarone; Antiviral Agents; Coinfection; Comorbidity; Drug Interactions; Female; Heart Diseases; H | 2018 |
Amiodarone-induced hypothyroidism with EPO-resistant anemia in a patient with chronic renal failure.
Topics: Aged, 80 and over; Amiodarone; Anemia; Anti-Arrhythmia Agents; Drug Resistance; Erythropoietin; Huma | 2008 |
[Difficult-to-treat atrial fibrillation in a patient on haemodialysis].
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Atrial Fibrillation; Bisoprolol; Bradycardia; Calcium | 2010 |
Case report: drug interaction between tacrolimus and amiodarone with QT prolongation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Diabetic Neph | 2010 |
[Rhabdomyolysis associated with atorvastatin combined with amiodarone and fluconazole].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anticholesteremic Agents; Antifungal Agents; Atorvastatin; | 2011 |
Development of refractory ascites during amiodarone therapy in a hemodialysis patient with nephrogenic and cardiogenic ascites.
Topics: Aged; Amiodarone; Ascites; Female; Heart Failure; Humans; Hypothyroidism; Kidney Failure, Chronic; P | 2012 |
Clinical evaluation of nine free thyroxine assays: persistent problems in particular populations.
Topics: Amiodarone; Anti-Arrhythmia Agents; Blood Chemical Analysis; Female; Humans; Hyperthyroidism; Kidney | 2003 |
Hyperglobulinemia in amiodarone-induced pneumonitis.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Female; Humans | 2007 |
Renal elimination of amiodarone and its desethyl metabolite.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Female; Humans; Kidney; Kidney Failure, Chronic; Male | 1983 |
Amiodarone in patients on long-term dialysis.
Topics: Adult; Aged; Amiodarone; Benzofurans; Female; Humans; Kidney Failure, Chronic; Male; Middle Aged; Re | 1983 |
Clinical comparison of three labeled-antibody immunoassays of free triiodothyronine.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Autoanalysis; Autoantibodies; Humans; Hypert | 1996 |
Disposition of intravenous amiodarone in subjects with normal and impaired renal function.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Glomerular Filtration Rate; Humans; Infusio | 1996 |
Interpretation of excessive serum concentrations of digoxin in children.
Topics: Adolescent; Amiodarone; Blood Proteins; Cardenolides; Digoxin; Drug Interactions; Female; Half-Life; | 1985 |
Effect of renal failure or biliary stasis on the pharmacokinetics of amiodarone in the rat.
Topics: Amiodarone; Animals; Benzofurans; Cholestasis; Dealkylation; Glucuronates; Kidney Failure, Chronic; | 1986 |