Page last updated: 2024-10-22

amiodarone and Kidney Diseases

amiodarone has been researched along with Kidney Diseases in 12 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone inhibits warfarin metabolism and is associated with major bleeding during warfarin therapy."3.96The Magnitude of the Warfarin-Amiodarone Drug-Drug Interaction Varies With Renal Function: A Propensity-Matched Cohort Study. ( Brown, JR; Hennessy, S; Miano, TA; Shashaty, MGS; Yang, W; Zuppa, A, 2020)
"Rivaroxaban (RXA) is a direct oral factor Xa (Xa) antagonist with a short half-life and a fast onset and offset of effect."1.48Risk Factors for Higher-than-Expected Residual Rivaroxaban Plasma Concentrations in Real-Life Patients. ( Jetter, A; Kaserer, A; Schedler, A; Seifert, B; Spahn, DR; Stein, P; Studt, JD, 2018)
"Rats treated with amiodarone had a higher serum creatinine (182%) and a lower glomerular filtration rate (53%), renal plasma flow (68%) and filtration fraction (62%) than controls."1.32Acute renal toxic effect of amiodarone in rats. ( Arévalo, MA; Barata, JD; Branco, P; Bruges, M; González de Buitrago, JM; Morales, AI; Palma, P; Pérez-Barriocanal, F, 2003)
"To understand the bioavailability and mechanistic pathways of cytoprotection by IH636 grape seed proanthocyanidin extract (GSPE, commercially known as ActiVin) a series of in vitro and in vivo studies were conducted."1.31Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract. ( Bagchi, D; Bagchi, M; Preuss, HG; Ray, SD; Stohs, SJ, 2002)
" The data were analyzed by nonlinear mixed-effects modeling (NONMEM) to estimate the population pharmacokinetic parameters of amiodarone and to determine the significant demographic covariates affecting these parameters."1.30Population pharmacokinetics of intravenous amiodarone and comparison with two-stage pharmacokinetic analysis. ( Chiang, ST; Korth-Bradley, J; Troy, S; Vadiei, K; Zimmerman, JJ, 1997)
" Also, no difference in efficacy of either drug was observed and changes in dosing of digoxin were not required."1.27Drug interaction studies and encainide use in renal and hepatic impairment. ( Gallo, DG; Quart, BD; Sami, MH; Wood, AJ, 1986)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19903 (25.00)18.7374
1990's1 (8.33)18.2507
2000's5 (41.67)29.6817
2010's1 (8.33)24.3611
2020's2 (16.67)2.80

Authors

AuthorsStudies
Miano, TA1
Yang, W1
Shashaty, MGS1
Zuppa, A1
Brown, JR1
Hennessy, S1
Rabia, M1
Leuzy, V1
Soulage, C1
Durand, A1
Fourmaux, B1
Errazuriz-Cerda, E1
Köffel, R1
Draeger, A1
Colosetti, P1
Jalabert, A1
Di Filippo, M1
Villard-Garon, A1
Bergerot, C1
Luquain-Costaz, C1
Moulin, P1
Rome, S1
Delton, I1
Hullin-Matsuda, F1
Kaserer, A1
Schedler, A1
Jetter, A1
Seifert, B1
Spahn, DR1
Stein, P1
Studt, JD1
Jamshidzadeh, A1
Baghban, M1
Azarpira, N1
Mohammadi Bardbori, A1
Niknahad, H1
Bagchi, D2
Ray, SD2
Bagchi, M1
Preuss, HG1
Stohs, SJ1
Morales, AI1
Barata, JD1
Bruges, M1
Arévalo, MA1
González de Buitrago, JM1
Palma, P1
Branco, P1
Pérez-Barriocanal, F1
Pintavorn, P1
Wartofsky, L1
Burman, KD1
Vadiei, K1
Troy, S1
Korth-Bradley, J1
Chiang, ST1
Zimmerman, JJ1
Patel, D1
Wong, V1
Quart, BD1
Gallo, DG1
Sami, MH1
Wood, AJ1
Caubarrère, I1
Bonan, G1
Venet, A1
Chebat, J1
Uzzan, D1
Gilbert, J1
Beaufils, H1

Reviews

1 review available for amiodarone and Kidney Diseases

ArticleYear
Alterations in thyroid function in patients with systemic illness: the "euthyroid sick syndrome".
    Endocrine reviews, 1982,Spring, Volume: 3, Issue:2

    Topics: Adult; Age Factors; Aged; Amiodarone; Animals; Anorexia Nervosa; Contrast Media; Diabetes Mellitus;

1982

Other Studies

11 other studies available for amiodarone and Kidney Diseases

ArticleYear
The Magnitude of the Warfarin-Amiodarone Drug-Drug Interaction Varies With Renal Function: A Propensity-Matched Cohort Study.
    Clinical pharmacology and therapeutics, 2020, Volume: 107, Issue:6

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Co

2020
Bis(monoacylglycero)phosphate, a new lipid signature of endosome-derived extracellular vesicles.
    Biochimie, 2020, Volume: 178

    Topics: Aged; Amiodarone; Animals; Anti-Arrhythmia Agents; Biomarkers; Endosomes; Extracellular Vesicles; Fe

2020
Risk Factors for Higher-than-Expected Residual Rivaroxaban Plasma Concentrations in Real-Life Patients.
    Thrombosis and haemostasis, 2018, Volume: 118, Issue:5

    Topics: Administration, Oral; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Blood Coagulation

2018
Effects of tomato extract on oxidative stress induced toxicity in different organs of rats.
    Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 2008, Volume: 46, Issue:12

    Topics: Acetaminophen; Amiodarone; Analgesics, Non-Narcotic; Animals; Anti-Arrhythmia Agents; Chemical and D

2008
Mechanistic pathways of antioxidant cytoprotection by a novel IH636 grape seed proanthocyanidin extract.
    Indian journal of experimental biology, 2002, Volume: 40, Issue:6

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Analgesics, Non-Narcotic; Ani

2002
Acute renal toxic effect of amiodarone in rats.
    Pharmacology & toxicology, 2003, Volume: 92, Issue:1

    Topics: Acute Disease; Amiodarone; Animals; Anti-Arrhythmia Agents; Creatinine; Injections, Intraperitoneal;

2003
A wild zebra chase.
    Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 2008, Volume: 23, Issue:5

    Topics: Amiodarone; Animals; Diagnosis, Differential; Fabry Disease; Female; Humans; Iatrogenic Disease; Kid

2008
Population pharmacokinetics of intravenous amiodarone and comparison with two-stage pharmacokinetic analysis.
    Journal of clinical pharmacology, 1997, Volume: 37, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Injections, Intr

1997
In vivo protection of dna damage associated apoptotic and necrotic cell deaths during acetaminophen-induced nephrotoxicity, amiodarone-induced lung toxicity and doxorubicin-induced cardiotoxicity by a novel IH636 grape seed proanthocyanidin extract.
    Research communications in molecular pathology and pharmacology, 2000, Volume: 107, Issue:1-2

    Topics: Acetaminophen; Administration, Oral; Alanine Transaminase; Amiodarone; Animals; Antioxidants; Apopto

2000
Drug interaction studies and encainide use in renal and hepatic impairment.
    The American journal of cardiology, 1986, Aug-29, Volume: 58, Issue:5

    Topics: Adrenergic beta-Antagonists; Adult; Amiodarone; Anilides; Anti-Arrhythmia Agents; Anticoagulants; An

1986
[Pneumopathies caused by hypersensitivity to amiodarone and associated nephropathies. Study by alveolar lavage].
    Annales de medecine interne, 1985, Volume: 136, Issue:4

    Topics: Acute Kidney Injury; Aged; Amiodarone; Benzofurans; Drug Hypersensitivity; Female; Humans; Kidney Di

1985