amiodarone has been researched along with Innate Inflammatory Response in 16 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this double-blind, placebo-controlled trial, patients at high risk of postoperative atrial fibrillation scheduled to undergo major thoracic surgery were randomized to N-acetylcysteine plus amiodarone or placebo plus amiodarone." | 9.51 | Amiodarone with or without N-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial. ( Amar, D; Chung, MK; Desiderio, D; Fischer, GW; Isbell, JM; Jones, DR; Meyers, BF; Milne, GL; Molena, D; Park, BJ; Pedoto, A; Roistacher, N; Rusch, VW; Tan, KS; Zhang, H, 2022) |
| "Heat exposure induces apoptosis, inflammation and oxidative stress in mouse HL1 atrial myocytes, and amiodarone can enhance the effects of heat exposure to aggravate the cell injuries." | 8.02 | [Amiodarone promotes heat-induced apoptosis, inflammation and oxidative stress in mouse HL1 atrial myocytes]. ( He, L; Kou, H; Peng, J; Tan, Z; Yan, R; Zhao, H; Zhu, S, 2021) |
| "To compare the early postarrest inflammatory cytokine response between animals administered amiodarone (AMIO) and lidocaine (LIDO) intra-arrest during resuscitation from ventricular fibrillation (VF)." | 7.79 | Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation. ( Niemann, JT; Rosborough, JP; Shah, AP; Thomas, JL; Youngquist, ST, 2013) |
| "Amiodarone, a cardiac antiarrhythmic agent, has been associated with the development of interstitial pulmonary fibrosis in patients receiving prolonged therapy with the drug." | 7.67 | Amiodarone-induced pulmonary fibrosis in hamsters. ( Cantor, JO; Cerreta, JM; Mandl, I; Osman, M; Suarez, R; Turino, GM, 1984) |
| "Some population pharmacokinetic models for amiodarone (AMD) did not incorporate N-desethylamiodarone (DEA) concentration." | 5.72 | Population Pharmacokinetic Model of Amiodarone and N-Desethylamiodarone Focusing on Glucocorticoid and Inflammation. ( Akai, N; Hanada, K; Hirai, T; Itoh, T; Iwamoto, T; Kasai, H; Takahashi, M; Uchida, S, 2022) |
| "In this double-blind, placebo-controlled trial, patients at high risk of postoperative atrial fibrillation scheduled to undergo major thoracic surgery were randomized to N-acetylcysteine plus amiodarone or placebo plus amiodarone." | 5.51 | Amiodarone with or without N-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial. ( Amar, D; Chung, MK; Desiderio, D; Fischer, GW; Isbell, JM; Jones, DR; Meyers, BF; Milne, GL; Molena, D; Park, BJ; Pedoto, A; Roistacher, N; Rusch, VW; Tan, KS; Zhang, H, 2022) |
| "Heat exposure induces apoptosis, inflammation and oxidative stress in mouse HL1 atrial myocytes, and amiodarone can enhance the effects of heat exposure to aggravate the cell injuries." | 4.02 | [Amiodarone promotes heat-induced apoptosis, inflammation and oxidative stress in mouse HL1 atrial myocytes]. ( He, L; Kou, H; Peng, J; Tan, Z; Yan, R; Zhao, H; Zhu, S, 2021) |
| "To compare the early postarrest inflammatory cytokine response between animals administered amiodarone (AMIO) and lidocaine (LIDO) intra-arrest during resuscitation from ventricular fibrillation (VF)." | 3.79 | Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation. ( Niemann, JT; Rosborough, JP; Shah, AP; Thomas, JL; Youngquist, ST, 2013) |
| "We evaluated the hypothesis that a relationship exists between inflammation and the outcome of pharmaceutical cardioversion with amiodarone in recent onset atrial fibrillation." | 3.74 | Interleukin-2 serum levels variations in recent onset atrial fibrillation are related with cardioversion outcome. ( Dragomanovits, S; Kalogeropoulos, AS; Kremastinos, DT; Papathanasiou, S; Rigopoulos, AG; Rizos, I; Sakadakis, EA; Tsiodras, S, 2007) |
| "Amiodarone, a cardiac antiarrhythmic agent, has been associated with the development of interstitial pulmonary fibrosis in patients receiving prolonged therapy with the drug." | 3.67 | Amiodarone-induced pulmonary fibrosis in hamsters. ( Cantor, JO; Cerreta, JM; Mandl, I; Osman, M; Suarez, R; Turino, GM, 1984) |
| "Some population pharmacokinetic models for amiodarone (AMD) did not incorporate N-desethylamiodarone (DEA) concentration." | 1.72 | Population Pharmacokinetic Model of Amiodarone and N-Desethylamiodarone Focusing on Glucocorticoid and Inflammation. ( Akai, N; Hanada, K; Hirai, T; Itoh, T; Iwamoto, T; Kasai, H; Takahashi, M; Uchida, S, 2022) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 3 (18.75) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 6 (37.50) | 2.80 |
| Authors | Studies |
|---|---|
| Gillmann, HJ | 1 |
| Busche, P | 1 |
| Leffler, A | 1 |
| Stueber, T | 1 |
| Amar, D | 1 |
| Zhang, H | 1 |
| Chung, MK | 1 |
| Tan, KS | 1 |
| Desiderio, D | 1 |
| Park, BJ | 1 |
| Pedoto, A | 1 |
| Roistacher, N | 1 |
| Isbell, JM | 1 |
| Molena, D | 1 |
| Milne, GL | 1 |
| Meyers, BF | 1 |
| Fischer, GW | 1 |
| Rusch, VW | 1 |
| Jones, DR | 1 |
| Hirai, T | 1 |
| Kasai, H | 1 |
| Takahashi, M | 1 |
| Uchida, S | 1 |
| Akai, N | 1 |
| Hanada, K | 1 |
| Itoh, T | 1 |
| Iwamoto, T | 1 |
| Radwan, SM | 1 |
| Ghoneim, D | 1 |
| Salem, M | 1 |
| Saeed, M | 1 |
| Saleh, Y | 1 |
| Elhamy, M | 1 |
| Wael, K | 1 |
| Shokair, O | 1 |
| Wahdan, SA | 1 |
| Eid, RA | 1 |
| Zaki, MSA | 1 |
| Al-Shraim, M | 1 |
| Eldeen, MA | 1 |
| Haidara, MA | 1 |
| Zhao, H | 1 |
| Tan, Z | 1 |
| He, L | 1 |
| Zhu, S | 1 |
| Yan, R | 1 |
| Kou, H | 1 |
| Peng, J | 1 |
| Youngquist, ST | 1 |
| Niemann, JT | 1 |
| Shah, AP | 1 |
| Thomas, JL | 1 |
| Rosborough, JP | 1 |
| Robinson, E | 1 |
| Kaushal, S | 1 |
| Alaboson, J | 1 |
| Sharma, S | 1 |
| Belagodu, A | 1 |
| Watkins, C | 1 |
| Walker, B | 1 |
| Webster, G | 1 |
| McCarthy, P | 1 |
| Ho, D | 1 |
| Ozaydın, M | 1 |
| Erdoğan, D | 1 |
| Tayyar, S | 1 |
| Uysal, BA | 1 |
| Doğan, A | 1 |
| Içli, A | 1 |
| Ozkan, E | 1 |
| Varol, E | 1 |
| Türker, Y | 1 |
| Arslan, A | 1 |
| Karth, GD | 1 |
| Buberl, A | 1 |
| Nikfardjam, M | 1 |
| Meyer, B | 1 |
| Wollenek, G | 1 |
| Grimm, M | 1 |
| Lassnigg, A | 1 |
| Brannath, W | 1 |
| Hiesmayr, M | 1 |
| Heinz, G | 1 |
| Rizos, I | 1 |
| Tsiodras, S | 1 |
| Rigopoulos, AG | 1 |
| Dragomanovits, S | 1 |
| Kalogeropoulos, AS | 1 |
| Papathanasiou, S | 1 |
| Sakadakis, EA | 1 |
| Kremastinos, DT | 1 |
| Blank, W | 1 |
| Braun, B | 1 |
| Cantor, JO | 1 |
| Osman, M | 1 |
| Cerreta, JM | 1 |
| Suarez, R | 1 |
| Mandl, I | 1 |
| Turino, GM | 1 |
| Perry, HD | 1 |
| Zitnik, RJ | 1 |
| Cooper, JA | 1 |
| Rankin, JA | 1 |
| Sussman, J | 1 |
| Israël-Biet, D | 1 |
| Venet, A | 1 |
| Caubarrère, I | 1 |
| Bonan, G | 1 |
| Danel, C | 1 |
| Chrétien, J | 1 |
| Hance, AJ | 1 |
3 trials available for amiodarone and Innate Inflammatory Response
| Article | Year |
|---|---|
Amiodarone with or without N-Acetylcysteine for the Prevention of Atrial Fibrillation after Thoracic Surgery: A Double-blind, Randomized Trial.
Topics: Acetylcysteine; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Dou | 2022 |
N-3 polyunsaturated fatty acids administration does not reduce the recurrence rates of atrial fibrillation and inflammation after electrical cardioversion: a prospective randomized study.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; C-Reactive | 2011 |
Role of amiodarone on the systemic inflammatory response induced by cardiac surgery: proinflammatory actions.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biomarkers; C-Reactive Protein; Chemokine CCL2; Coronary A | 2007 |
13 other studies available for amiodarone and Innate Inflammatory Response
| Article | Year |
|---|---|
Effectiveness of amiodarone versus digitalis for heart rate control in critically ill patients with new-onset atrial fibrillation.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Critical Illness; | 2022 |
Population Pharmacokinetic Model of Amiodarone and N-Desethylamiodarone Focusing on Glucocorticoid and Inflammation.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Cytochrome P-450 CYP3A; Glucocorticoids; Humans; Inflamma | 2022 |
Adipose Tissue-Derived Mesenchymal Stem Cells Protect Against Amiodarone-Induced Lung Injury in Rats.
Topics: Actins; Adipose Tissue; Amiodarone; Animals; Cell Proliferation; Fibroblast Growth Factor 7; Flow Cy | 2020 |
Grape seed extract protects against amiodarone - induced nephrotoxicity and ultrastructural alterations associated with the inhibition of biomarkers of inflammation and oxidative stress in rats.
Topics: Amiodarone; Animals; Antioxidants; Biomarkers; Grape Seed Extract; Inflammation; Oxidative Stress; R | 2021 |
[Amiodarone promotes heat-induced apoptosis, inflammation and oxidative stress in mouse HL1 atrial myocytes].
Topics: Amiodarone; Animals; Apoptosis; Hot Temperature; Inflammation; Mice; Oxidative Stress | 2021 |
Administration of amiodarone during resuscitation is associated with higher tumor necrosis factor-α levels in the early postarrest period in the swine model of ischemic ventricular fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiopulmonary Resuscitation; Coronary Vessels; Diseas | 2013 |
Combinatorial release of dexamethasone and amiodarone from a nano-structured parylene-C film to reduce perioperative inflammation and atrial fibrillation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atrial Fibrillation; Cell Survival; Dexamethasone; Drug | 2016 |
Interleukin-2 serum levels variations in recent onset atrial fibrillation are related with cardioversion outcome.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; C-Reactive Protein | 2007 |
[Sonography of the thyroid--part 2: thyroid inflammation, impairmant of thyroid function and interventions].
Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Chronic Disease; Female; Humans; Hyperthyroidism; | 2008 |
Amiodarone-induced pulmonary fibrosis in hamsters.
Topics: Amiodarone; Animals; Benzofurans; Cricetinae; Hemorrhage; Inflammation; Lung; Lung Diseases; Mesocri | 1984 |
Drugs and toxins.
Topics: Adult; Amiodarone; Child; Conjunctivitis; Corneal Diseases; Eye Diseases; Female; Humans; Idoxuridin | 1983 |
Effects of in vitro amiodarone exposure on alveolar macrophage inflammatory mediator production.
Topics: Amiodarone; Animals; Cell Adhesion; Fibronectins; In Vitro Techniques; Inflammation; Leukotriene B4; | 1992 |
Bronchoalveolar lavage in amiodarone pneumonitis. Cellular abnormalities and their relevance to pathogenesis.
Topics: Aged; Alveolitis, Extrinsic Allergic; Amiodarone; Bronchi; Cell Separation; Female; Humans; Immunity | 1987 |