amiodarone has been researched along with Injury, Myocardial Reperfusion in 19 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The purpose of this study was to evaluate the efficacy of prophylactic single-dose amiodarone administered through the pump circuit before releasing the aortic cross-clamp (ACC) in preventing the occurrence of reperfusion ventricular fibrillation (RVF)." | 9.14 | Amiodarone for the prevention of reperfusion ventricular fibrillation. ( Chandra, A; Panigrahi, S; Samantaray, A, 2010) |
| "We studied the use of perioperative IV and oral administration of amiodarone for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass graft surgery (CABG)." | 9.11 | Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study. ( Hollander, G; Kerstein, J; Lichstein, E; Majid, M; Qamar, M; Shani, J; Soodan, A, 2004) |
| "The effects of short-term amiodarone and dronedarone treatments on action potential characteristics and arrhythmia (ventricular tachycardia ) induced by reperfusion after global low-flow ischemia were studied in rat hearts." | 7.71 | Beneficial effects of amiodarone and dronedarone (SR 33589b), when applied during low-flow ischemia, on arrhythmia and functional parameters asssessed during reperfusion in isolated rat hearts. ( Barbé, C; Kreher, P; Rochetaing, A, 2001) |
| "We have assessed the ability of the new amiodarone-like antiarrhythmic agent, SR 33589, to reduce the incidence of ischemia- and reperfusion-induced arrhythmias, in comparison to amiodarone, D-sotalol, and lignocaine." | 7.69 | SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. ( Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J, 1995) |
| "The effects of amiodarone and its metabolite desethylamiodarone on arrhythmias induced by ischaemia and reperfusion were studied in vivo in the anaesthetised rat with transient regional ischaemia (7 min of left coronary artery occlusion) and reperfusion (10 min)." | 7.67 | Anti-arrhythmic effects of amiodarone and desethylamiodarone on malignant ventricular arrhythmias arising as a consequence of ischaemia and reperfusion in the anaesthetised rat. ( Hearse, DJ; Riva, E, 1989) |
| "The score of arrhythmia severity also decreased, but was statistically significant only in the Amio group (p < 0." | 5.40 | Efficacy of Melissa officinalis in suppressing ventricular arrhythmias following ischemia-reperfusion of the heart: a comparison with amiodarone. ( Bashiri, A; Joukar, S; Sepehri, G; Zarisfi, Z, 2014) |
| "Dronedarone was given in Wistar rats (90 mg/kg, once daily (od) for 2 weeks) (DRON), while untreated animals served as controls (CONT)." | 5.33 | Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor alpha1. ( Cokkinos, DV; Malliopoulou, V; Moraitis, P; Mourouzis, I; Paizis, I; Pantos, C; Sfakianoudis, K; Tzeis, S; Varonos, DD, 2005) |
| "The duration of arrhythmias induced by reperfusion following 5 min of ischaemia was also less in the rats which had received amiodarone than in the controls (43." | 5.28 | Amiodarone, adrenoceptor responsiveness and ischaemia- and reperfusion-induced arrhythmias. ( Chess-Williams, R; Coker, SJ, 1991) |
| "The purpose of this study was to evaluate the efficacy of prophylactic single-dose amiodarone administered through the pump circuit before releasing the aortic cross-clamp (ACC) in preventing the occurrence of reperfusion ventricular fibrillation (RVF)." | 5.14 | Amiodarone for the prevention of reperfusion ventricular fibrillation. ( Chandra, A; Panigrahi, S; Samantaray, A, 2010) |
| "We studied the use of perioperative IV and oral administration of amiodarone for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass graft surgery (CABG)." | 5.11 | Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study. ( Hollander, G; Kerstein, J; Lichstein, E; Majid, M; Qamar, M; Shani, J; Soodan, A, 2004) |
| "Targeting the delivery of liposomal amiodarone to ischemic/reperfused myocardium reduces the mortality due to lethal arrhythmia and the negative hemodynamic changes caused by amiodarone." | 3.79 | Liposomal amiodarone augments anti-arrhythmic effects and reduces hemodynamic adverse effects in an ischemia/reperfusion rat model. ( Asai, T; Asakura, M; Asano, Y; Asanuma, H; Fu, HY; Kitakaze, M; Komuro, I; Matsuzaki, T; Minamino, T; Oku, N; Okuda, K; Sanada, S; Shigematsu, H; Takahama, H; Yamato, M, 2013) |
| "The effects of short-term amiodarone and dronedarone treatments on action potential characteristics and arrhythmia (ventricular tachycardia ) induced by reperfusion after global low-flow ischemia were studied in rat hearts." | 3.71 | Beneficial effects of amiodarone and dronedarone (SR 33589b), when applied during low-flow ischemia, on arrhythmia and functional parameters asssessed during reperfusion in isolated rat hearts. ( Barbé, C; Kreher, P; Rochetaing, A, 2001) |
| "We have assessed the ability of the new amiodarone-like antiarrhythmic agent, SR 33589, to reduce the incidence of ischemia- and reperfusion-induced arrhythmias, in comparison to amiodarone, D-sotalol, and lignocaine." | 3.69 | SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats. ( Bruyninckx, C; Chatelain, P; Manning, AS; Ramboux, J, 1995) |
| "The effects of amiodarone and its metabolite desethylamiodarone on arrhythmias induced by ischaemia and reperfusion were studied in vivo in the anaesthetised rat with transient regional ischaemia (7 min of left coronary artery occlusion) and reperfusion (10 min)." | 3.67 | Anti-arrhythmic effects of amiodarone and desethylamiodarone on malignant ventricular arrhythmias arising as a consequence of ischaemia and reperfusion in the anaesthetised rat. ( Hearse, DJ; Riva, E, 1989) |
| "The score of arrhythmia severity also decreased, but was statistically significant only in the Amio group (p < 0." | 1.40 | Efficacy of Melissa officinalis in suppressing ventricular arrhythmias following ischemia-reperfusion of the heart: a comparison with amiodarone. ( Bashiri, A; Joukar, S; Sepehri, G; Zarisfi, Z, 2014) |
| "The results suggest that pretreatment with saffron, especially at the dosage of 100 mg/kg/day, attenuates the susceptibility and incidence of fatal ventricular arrhythmia during the reperfusion period in the rat." | 1.39 | Protective effects of saffron (Crocus sativus) against lethal ventricular arrhythmias induced by heart reperfusion in rat: a potential anti-arrhythmic agent. ( Bashiri, A; Ghasemipour-Afshar, E; Joukar, S; Naghsh, N; Sheibani, M, 2013) |
| "Dronedarone is a first-line drug to prevent the recurrence of atrial fibrillation according to ESC guidelines." | 1.37 | Reduction of myocardial infarct size by dronedarone in pigs--a pleiotropic action? ( Heusch, G; Skyschally, A, 2011) |
| "Dronedarone was given in Wistar rats (90 mg/kg, once daily (od) for 2 weeks) (DRON), while untreated animals served as controls (CONT)." | 1.33 | Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor alpha1. ( Cokkinos, DV; Malliopoulou, V; Moraitis, P; Mourouzis, I; Paizis, I; Pantos, C; Sfakianoudis, K; Tzeis, S; Varonos, DD, 2005) |
| "Amiodarone was administered orally at 15 mg/kg/day for an average of 28 days to a group of 10 dogs." | 1.28 | Hemodynamic effects of oral amiodarone on left ventricular function before and after global ischemia. ( Allen, M; Ivev, TD; Misbach, GA; Miyamoto, M; Tabayashi, K; Thomas, R; Togo, T, 1992) |
| "The duration of arrhythmias induced by reperfusion following 5 min of ischaemia was also less in the rats which had received amiodarone than in the controls (43." | 1.28 | Amiodarone, adrenoceptor responsiveness and ischaemia- and reperfusion-induced arrhythmias. ( Chess-Williams, R; Coker, SJ, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (5.26) | 18.7374 |
| 1990's | 5 (26.32) | 18.2507 |
| 2000's | 5 (26.32) | 29.6817 |
| 2010's | 8 (42.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Joukar, S | 2 |
| Ghasemipour-Afshar, E | 1 |
| Sheibani, M | 1 |
| Naghsh, N | 1 |
| Bashiri, A | 2 |
| Alexandre, J | 1 |
| Rouet, R | 1 |
| Puddu, PE | 1 |
| Beygui, F | 1 |
| Manrique, A | 1 |
| Milliez, P | 1 |
| Zarisfi, Z | 1 |
| Sepehri, G | 1 |
| Wang, M | 1 |
| Shan, J | 1 |
| Yang, Q | 1 |
| Ma, X | 1 |
| Jin, S | 1 |
| Guo, X | 1 |
| You, Q | 1 |
| Tang, Y | 1 |
| Samantaray, A | 1 |
| Chandra, A | 1 |
| Panigrahi, S | 1 |
| Skyschally, A | 1 |
| Heusch, G | 1 |
| Goegelein, H | 1 |
| Gautier, P | 1 |
| Roccon, A | 1 |
| O'Connor, S | 1 |
| Ruetten, H | 1 |
| Takahama, H | 1 |
| Shigematsu, H | 1 |
| Asai, T | 1 |
| Matsuzaki, T | 1 |
| Sanada, S | 1 |
| Fu, HY | 1 |
| Okuda, K | 1 |
| Yamato, M | 1 |
| Asanuma, H | 1 |
| Asano, Y | 1 |
| Asakura, M | 1 |
| Oku, N | 1 |
| Komuro, I | 1 |
| Kitakaze, M | 1 |
| Minamino, T | 1 |
| Vergely, C | 1 |
| Renard, C | 1 |
| Moreau, D | 1 |
| Perrin- Sarrado, C | 1 |
| Roubaud, V | 1 |
| Tuccio, B | 1 |
| Rochette, L | 1 |
| Kerstein, J | 1 |
| Soodan, A | 1 |
| Qamar, M | 1 |
| Majid, M | 1 |
| Lichstein, E | 1 |
| Hollander, G | 1 |
| Shani, J | 1 |
| Pantos, C | 1 |
| Mourouzis, I | 1 |
| Malliopoulou, V | 1 |
| Paizis, I | 1 |
| Tzeis, S | 1 |
| Moraitis, P | 1 |
| Sfakianoudis, K | 1 |
| Varonos, DD | 1 |
| Cokkinos, DV | 1 |
| Kálai, T | 1 |
| Várbiró, G | 1 |
| Bognár, Z | 1 |
| Pálfi, A | 1 |
| Hantó, K | 1 |
| Bognár, B | 1 |
| Osz, E | 1 |
| Sümegi, B | 1 |
| Hideg, K | 1 |
| Manning, AS | 1 |
| Bruyninckx, C | 1 |
| Ramboux, J | 1 |
| Chatelain, P | 1 |
| Galenko-Iaroshevskiĭ, PA | 1 |
| Kryzhanovskiĭ, SA | 1 |
| Uvarov, AV | 1 |
| Turovaia, AIu | 1 |
| Popov, PB | 1 |
| Khankoeva, AI | 1 |
| Rochetaing, A | 1 |
| Barbé, C | 1 |
| Kreher, P | 1 |
| Tabayashi, K | 1 |
| Misbach, GA | 1 |
| Miyamoto, M | 1 |
| Togo, T | 1 |
| Allen, M | 1 |
| Thomas, R | 1 |
| Ivev, TD | 1 |
| Coker, SJ | 1 |
| Chess-Williams, R | 1 |
| Karlson, JA | 1 |
| Hopkins, RW | 1 |
| Moran, JM | 1 |
| Karlson, KE | 1 |
| Riva, E | 1 |
| Hearse, DJ | 1 |
2 trials available for amiodarone and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Amiodarone for the prevention of reperfusion ventricular fibrillation.
Topics: Adult; Amiodarone; Double-Blind Method; Female; Humans; Male; Middle Aged; Myocardial Reperfusion; M | 2010 |
Giving IV and oral amiodarone perioperatively for the prevention of postoperative atrial fibrillation in patients undergoing coronary artery bypass surgery: the GAP study.
Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Case-Control St | 2004 |
17 other studies available for amiodarone and Injury, Myocardial Reperfusion
| Article | Year |
|---|---|
Protective effects of saffron (Crocus sativus) against lethal ventricular arrhythmias induced by heart reperfusion in rat: a potential anti-arrhythmic agent.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Crocus; Disease Models, Animal; Dose | 2013 |
Dronedarone versus amiodarone in preventing premature ventricular contractions in an in vitro model of "border zone".
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Dronedarone; Electroc | 2014 |
Efficacy of Melissa officinalis in suppressing ventricular arrhythmias following ischemia-reperfusion of the heart: a comparison with amiodarone.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Disease Models, A | 2014 |
Antiarrhythmic efficacy of CPUY102122, a multiple ion channel blocker, on rabbits with ischemia/reperfusion injury.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antioxidants; Cardiotonic Agents; CHO Cells; Connexin 4 | 2014 |
Reduction of myocardial infarct size by dronedarone in pigs--a pleiotropic action?
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Pressure; Calcium; Cardiotonic Agents; Coronary C | 2011 |
Effects of the novel amiodarone-like compound SAR114646A on cardiac ion channels and ventricular arrhythmias in rats.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; CHO Cells; Cricetinae; Cricetulus; D | 2011 |
Liposomal amiodarone augments anti-arrhythmic effects and reduces hemodynamic adverse effects in an ischemia/reperfusion rat model.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Disease Models, Animal; Hemodynam | 2013 |
Effect of two new PBN-derived phosphorylated nitrones against postischaemic ventricular dysrhythmias.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cyclic N-Oxides; Dose-Response Re | 2003 |
Dronedarone administration prevents body weight gain and increases tolerance of the heart to ischemic stress: a possible involvement of thyroid hormone receptor alpha1.
Topics: Adaptation, Physiological; Amiodarone; Animals; Calcium-Transporting ATPases; Dronedarone; Eating; G | 2005 |
Synthesis and evaluation of the permeability transition inhibitory characteristics of paramagnetic and diamagnetic amiodarone derivatives.
Topics: Amiodarone; Animals; Cell Line; Cell Survival; Cells, Cultured; Energy Metabolism; Hepatocytes; Huma | 2005 |
SR 33589, a new amiodarone-like agent: effect on ischemia- and reperfusion-induced arrhythmias in anesthetized rats.
Topics: Administration, Oral; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzofurans | 1995 |
[Cardioprotective effects of the cyclic derivative of gamma-aminobutyric acid T3-146 during reperfusion].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cats; Electr | 1997 |
Beneficial effects of amiodarone and dronedarone (SR 33589b), when applied during low-flow ischemia, on arrhythmia and functional parameters asssessed during reperfusion in isolated rat hearts.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Circu | 2001 |
Hemodynamic effects of oral amiodarone on left ventricular function before and after global ischemia.
Topics: Administration, Oral; Amiodarone; Animals; Dogs; Hemodynamics; Myocardial Reperfusion Injury; Ventri | 1992 |
Amiodarone, adrenoceptor responsiveness and ischaemia- and reperfusion-induced arrhythmias.
Topics: Amiodarone; Animals; Arrhythmias, Cardiac; Coronary Disease; In Vitro Techniques; Male; Myocardial C | 1991 |
Long-term amiodarone administration protects against global myocardial ischemia.
Topics: Amiodarone; Animals; Cardiomegaly; Heart; Heart Arrest, Induced; Male; Myocardial Reperfusion Injury | 1990 |
Anti-arrhythmic effects of amiodarone and desethylamiodarone on malignant ventricular arrhythmias arising as a consequence of ischaemia and reperfusion in the anaesthetised rat.
Topics: Amiodarone; Anesthesia, Intravenous; Animals; Arrhythmias, Cardiac; Coronary Disease; Heart Ventricl | 1989 |