amiodarone has been researched along with Injury, Ischemia-Reperfusion in 6 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In the present manuscript we critically review the available evidence for pleiotropic effects of dronedarone in settings of myocardial and cerebral ischemia/reperfusion, both from experimental and clinical data." | 8.88 | Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain. ( Heusch, G; Schulz, R, 2012) |
| "In the present manuscript we critically review the available evidence for pleiotropic effects of dronedarone in settings of myocardial and cerebral ischemia/reperfusion, both from experimental and clinical data." | 4.88 | Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain. ( Heusch, G; Schulz, R, 2012) |
| "Reperfusion injury was assessed by post-ischemic recovery of left ventricular developed pressure (LVDP%) and LDH release." | 1.37 | Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor. ( Brozou, V; Cokkinos, DV; Galanopoulos, G; Kostopanagiotou, G; Mourouzis, I; Pantos, C; Saranteas, T, 2011) |
| "Amiodarone, when was present at low concentrations and predominantly in membrane bound form, protected heart and mitochondrial energy metabolism from ischemia-reperfusion-induced damages in Langendorff-perfused heart model." | 1.32 | Concentration dependent mitochondrial effect of amiodarone. ( Gallyas, F; Sumegi, B; Tapodi, A; Toth, A; Varbiro, G; Veres, B, 2003) |
| "Amiodarone is a widely used and potent antiarrhythmic agent that is metabolized to desethylamiodarone." | 1.32 | Protective effect of amiodarone but not N-desethylamiodarone on postischemic hearts through the inhibition of mitochondrial permeability transition. ( Bognar, Z; Gallyas, F; Sumegi, B; Tapodi, A; Toth, A; Varbiro, G; Veres, B, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 3 (50.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pantos, C | 1 |
| Mourouzis, I | 1 |
| Saranteas, T | 1 |
| Brozou, V | 1 |
| Galanopoulos, G | 1 |
| Kostopanagiotou, G | 1 |
| Cokkinos, DV | 1 |
| Heusch, G | 1 |
| Schulz, R | 1 |
| Varbiro, G | 3 |
| Toth, A | 2 |
| Tapodi, A | 3 |
| Veres, B | 2 |
| Sumegi, B | 3 |
| Gallyas, F | 3 |
| Bognar, Z | 2 |
| Kalai, T | 1 |
| Palfi, A | 1 |
| Hanto, K | 1 |
| Bognar, B | 1 |
| Mark, L | 1 |
| Szabo, Z | 1 |
| Radnai, B | 1 |
| Sarszegi, Z | 1 |
| Szanto, A | 1 |
| Hideg, K | 1 |
| Liu, P | 1 |
| Fei, L | 1 |
| Wu, W | 1 |
| Li, J | 1 |
| Wang, J | 1 |
| Zhang, X | 1 |
1 review available for amiodarone and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Pleiotropic effects of dronedarone on ischemia/reperfusion injury in heart and brain.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Brain Ischemia; Dronedarone; Humans; Myocardial Ischemi | 2012 |
5 other studies available for amiodarone and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Acute T3 treatment protects the heart against ischemia-reperfusion injury via TRα1 receptor.
Topics: Amiodarone; Animals; Dronedarone; Drug Synergism; Heart; In Vitro Techniques; Male; Myocardial Contr | 2011 |
Concentration dependent mitochondrial effect of amiodarone.
Topics: Amiodarone; Animals; Cell Membrane Permeability; Cell Survival; Dose-Response Relationship, Drug; En | 2003 |
Protective effect of amiodarone but not N-desethylamiodarone on postischemic hearts through the inhibition of mitochondrial permeability transition.
Topics: Amiodarone; Animals; Apoptosis Inducing Factor; Biological Transport; Disease Models, Animal; Energy | 2003 |
A novel SOD-mimetic permeability transition inhibitor agent protects ischemic heart by inhibiting both apoptotic and necrotic cell death.
Topics: Amiodarone; Animals; Apoptosis; Cytochromes c; Humans; Ischemia; Jurkat Cells; Magnetic Resonance Sp | 2006 |
Effects of hypothyroidism on the vulnerability to ventricular fibrillation in dogs: a comparative study with amiodarone.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Pressure; Disease Models, Anim | 1996 |