Page last updated: 2024-10-22

amiodarone and Hypotension

amiodarone has been researched along with Hypotension in 45 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.

Research Excerpts

ExcerptRelevanceReference
"Atrial fibrillation occurred in 15% of the patients receiving placebo and in 8% of the patients receiving verapamil (difference not significant)."9.08Verapamil as prophylactic treatment for atrial fibrillation after lung operations. ( Demedts, M; Demuynck, K; Deneffe, G; Lacquet, L; Tits, G; Tjandra-Maga, T; Van Mieghem, W, 1996)
"The identified trials were eligible for meta-analysis if they met the following criteria: patients had recent-onset atrial fibrillation; patients were randomized to intravenous amiodarone, placebo, or another antiarrhythmic agent; no other antiarrhythmic agent except digoxin was administered simultaneously with intravenous amiodarone or other active treatments; the number and percentage of conversions to sinus rhythm after treatment began were reported; and the number and type of adverse drug reactions occurring after treatment began were reported."8.81Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials. ( Hilleman, DE; Spinler, SA, 2002)
"Poisoning with flecainide acetate is rare and associated with a high mortality."8.80[Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999)
"The use of amiodarone for postoperative atrial fibrillation (AF) is widespread; however, there is a paucity of data on the optimal duration of overlap when transitioning from intravenous (IV) to oral amiodarone."8.12Intravenous to Oral Transition of Amiodarone (IOTA): Effect of Various Durations of Overlap on Atrial Fibrillation Recurrence After Cardiothoracic Surgery. ( Lam, JC; Lee, YG; Maurer, J; Patanwala, AE; Radosevich, JJ; Stevenson, B, 2022)
"Intravenous amiodarone can cause severe and refractory hypotension."7.81Amiodarone-Induced Life-Threatening Refractory Hypotension. ( Doshi, D; Jayawardana, R, 2015)
"We present a case of severe acute kidney injury (AKI) occurring shortly after the initiation of dronedarone therapy, which we suspect was the result of an adverse drug reaction."7.79Reversible acute kidney injury requiring haemodialysis five days after starting dronedarone in a stable 71-year-old man at risk of cardiovascular polypharmacy. ( Leaver, L; Maruthappu, M; Wayne, RP; Young, C, 2013)
"Eleven critically ill patients with life-threatening cardiac arrhythmias refractory to currently approved antiarrhythmic drugs were treated with intravenous amiodarone."7.67Intravenous amiodarone in the treatment of refractory life-threatening cardiac arrhythmias in the critically ill patient. ( Leak, D, 1986)
"Hepatotoxicity due to intravenous amiodarone (HIVAD) is a rare side effect with a distinct pattern of enzyme disturbances compared to liver damage from oral amiodarone."5.37Acute amiodarone liver toxicity likely due to ischemic hepatitis. ( Fried, M; Gluck, N; Porat, R, 2011)
"The initial arrhythmia was 2/1 atrial flutter (n = 4), 1/1 atrial flutter (n = 2) and atrial fibrillation (n = 1)."5.31[Atrial flutter with 1/1 nodo-ventricular conduction with amiodarone. From physiopathology to diagnosis]. ( Aouate, P; Dubois-Randé, JL; Elbaz, N; Fontaine, G; Frank, R; Klug, D; Lacotte, J; Lelouche, D; Raguin, D; Tonet, J, 2002)
"Hypotension is the most frequent adverse event reported with intravenous amiodarone."5.11Lack of a hypotensive effect with rapid administration of a new aqueous formulation of intravenous amiodarone. ( Bailin, SJ; Borbola, J; Bridges, DE; Haffajee, CI; Kerin, NZ; Lakatos, F; Molnar, J; Paladino, WP; Sarosi, I; Somberg, JC; Tarjan, J; Timar, S, 2004)
"The duration, severity, and cause of hypotension after intravenous amiodarone has not been well characterized in anesthetized cardiac surgical patients."5.10Acute circulatory actions of intravenous amiodarone loading in cardiac surgical patients. ( Augoustides, JG; Cheung, AT; Gardner, TJ; Harrington, A; Levy, WJ; Savino, JS; Weiss, SJ, 2003)
"Atrial fibrillation occurred in 15% of the patients receiving placebo and in 8% of the patients receiving verapamil (difference not significant)."5.08Verapamil as prophylactic treatment for atrial fibrillation after lung operations. ( Demedts, M; Demuynck, K; Deneffe, G; Lacquet, L; Tits, G; Tjandra-Maga, T; Van Mieghem, W, 1996)
"The identified trials were eligible for meta-analysis if they met the following criteria: patients had recent-onset atrial fibrillation; patients were randomized to intravenous amiodarone, placebo, or another antiarrhythmic agent; no other antiarrhythmic agent except digoxin was administered simultaneously with intravenous amiodarone or other active treatments; the number and percentage of conversions to sinus rhythm after treatment began were reported; and the number and type of adverse drug reactions occurring after treatment began were reported."4.81Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials. ( Hilleman, DE; Spinler, SA, 2002)
"Poisoning with flecainide acetate is rare and associated with a high mortality."4.80[Severe flecainide acetate poisoning. Apropos of a case]. ( Chevrolet, JC; Elamly, A; Maury, P; Metzger, J; Schoenenberger, I; Veragut, B; Vuille, C, 1999)
"The use of amiodarone for postoperative atrial fibrillation (AF) is widespread; however, there is a paucity of data on the optimal duration of overlap when transitioning from intravenous (IV) to oral amiodarone."4.12Intravenous to Oral Transition of Amiodarone (IOTA): Effect of Various Durations of Overlap on Atrial Fibrillation Recurrence After Cardiothoracic Surgery. ( Lam, JC; Lee, YG; Maurer, J; Patanwala, AE; Radosevich, JJ; Stevenson, B, 2022)
"Intravenous amiodarone can cause severe and refractory hypotension."3.81Amiodarone-Induced Life-Threatening Refractory Hypotension. ( Doshi, D; Jayawardana, R, 2015)
"Two of the excipients in intravenous formulations of amiodarone, polysorbate 80 and benzyl alcohol, have been shown to cause hypotension."3.81Evaluation of the Hemodynamic Effects of Intravenous Amiodarone Formulations During the Maintenance Phase Infusion. ( Fleming, T; Heidel, E; Lindquist, DE; Rowe, AS; Yates, JR, 2015)
"We present a case of severe acute kidney injury (AKI) occurring shortly after the initiation of dronedarone therapy, which we suspect was the result of an adverse drug reaction."3.79Reversible acute kidney injury requiring haemodialysis five days after starting dronedarone in a stable 71-year-old man at risk of cardiovascular polypharmacy. ( Leaver, L; Maruthappu, M; Wayne, RP; Young, C, 2013)
" Hypotension frequently occurs with use of intravenous amiodarone and is managed by slowing the rate of administration."3.76The hypotensive effect of intravenous amiodarone is sustained throughout the maintenance infusion period. ( Cooper, WD; Cushing, DJ; Gralinski, MR; Lipicky, RJ, 2010)
"Our objective is to investigate to what extent amiodarone is sequestered by intravenously administered lipid emulsion in plasma of pigs and whether the lipid emulsion inhibits amiodarone-induced hypotension."3.76Intravenous lipid emulsion sequesters amiodarone in plasma and eliminates its hypotensive action in pigs. ( Litonius, E; Neuvonen, PJ; Niiya, T; Petäjä, L; Rosenberg, PH, 2010)
" administration is systemic hypotension which has been attributed to the cosolvents used in the formulation, polysorbate 80 and benzyl alcohol."3.75PM101: a cyclodextrin-based intravenous formulation of amiodarone devoid of adverse hemodynamic effects. ( Cooper, WD; Cushing, DJ; Gralinski, MR; Kowey, PR; Lipicky, RJ; Massey, BW, 2009)
"This study was designed to test the hypothesis that rapid bolus administration of an aqueous formulation of intravenous amiodarone causes less hypotension than a 10-minute infusion of the standard formulation, Cordarone IV."3.72Comparative effects of rapid bolus administration of aqueous amiodarone versus 10-minute cordarone I.v. infusion on mean arterial blood pressure in conscious dogs. ( Cvetanovic, I; Molnar, J; Ranade, V; Somberg, JC, 2004)
"Eleven critically ill patients with life-threatening cardiac arrhythmias refractory to currently approved antiarrhythmic drugs were treated with intravenous amiodarone."3.67Intravenous amiodarone in the treatment of refractory life-threatening cardiac arrhythmias in the critically ill patient. ( Leak, D, 1986)
" Thus, in these patients, the speed and dosing accuracy of an intravenous formulation would be beneficial."2.68Dose-ranging study of intravenous amiodarone in patients with life-threatening ventricular tachyarrhythmias. The Intravenous Amiodarone Multicenter Investigators Group. ( Cannom, DS; Chilson, DA; Friehling, T; Kopelman, HA; Kowey, PR; Levine, JH; Platia, EV; Scheinman, MM; Wilber, DJ, 1995)
" However, there was no clear dose-response relation observed in this trial with respect to success rates (primary end point), time to first recurrence of tachyarrhythmia (post hoc analysis) or mortality (secondary end point) over 24 h."2.68Intravenous amiodarone for recurrent sustained hypotensive ventricular tachyarrhythmias. Intravenous Amiodarone Multicenter Trial Group. ( Chilson, DA; Gomes, A; Levine, JH; Massumi, A; Platia, EV; Scheinman, MM; Winkle, RA; Woosley, RL, 1996)
"Hepatotoxicity due to intravenous amiodarone (HIVAD) is a rare side effect with a distinct pattern of enzyme disturbances compared to liver damage from oral amiodarone."1.37Acute amiodarone liver toxicity likely due to ischemic hepatitis. ( Fried, M; Gluck, N; Porat, R, 2011)
"On admission, 7 patients had a congestive heart failure and 3 of whom had cardiovascular collapse."1.36Intravenous amiodarone used alone or in combination with digoxin for life-threatening supraventricular tachyarrhythmia in neonates and small infants. ( Aslan, Y; Celiker, A; Dilber, B; Dilber, E; Gedik, Y; Mutlu, M, 2010)
"Procainamide was not more effective than amiodarone for the termination of sustained VT, but the ability to detect a significant difference was limited by the study design and potential confounding."1.36Amiodarone or procainamide for the termination of sustained stable ventricular tachycardia: an historical multicenter comparison. ( deSouza, IS; Ellinor, PT; Marill, KA; Nishijima, DK; Ruskin, JN; Senecal, EL; Setnik, GS; Stair, TO, 2010)
"Amiodarone is a potent anti-arrhythmic with a large pharmacological spectrum that shares the mechanisms of action of all classes of anti-arrhythmic drugs."1.33Acute cardiodepressant effects induced by bolus intravenous administration of amiodarone in rabbits. ( Lessa, MA; Tibiriçá, E, 2005)
"Sustained monomorphic ventricular tachycardia was defined as a tachycardia with uninterrupted duration or rapid recurrence despite automatic internal cardiac defibrillator therapy for at least 5 minutes before amiodarone treatment, monomorphic morphology, rate greater than 120 beats/min, QRS duration greater than 120 ms, and subsequently determined to be ventricular tachycardia by ECG criteria (eg, atrioventricular dissociation), implanted device interrogation, or formal electrophysiology study."1.33Amiodarone is poorly effective for the acute termination of ventricular tachycardia. ( deSouza, IS; Marill, KA; Nishijima, DK; Ruskin, JN; Setnik, GS; Stair, TO, 2006)
"We report a case of a patient with paroxysmal atrial fibrillation (PAF) and with a permanent AAIR (bipolar atrial-inhibited adaptive rate) pacemaker who suffered life-threatening episodes of arrhythmias during operation."1.33Anesthetic management of an AAI pacemaker patient with paroxysmal atrial fibrillation during colorectal surgery. ( Borel, CO; Lin, JA; Wang, WB; Wong, CS; Wu, CT; Yang, CP; Yeh, CC, 2006)
"The initial arrhythmia was 2/1 atrial flutter (n = 4), 1/1 atrial flutter (n = 2) and atrial fibrillation (n = 1)."1.31[Atrial flutter with 1/1 nodo-ventricular conduction with amiodarone. From physiopathology to diagnosis]. ( Aouate, P; Dubois-Randé, JL; Elbaz, N; Fontaine, G; Frank, R; Klug, D; Lacotte, J; Lelouche, D; Raguin, D; Tonet, J, 2002)

Research

Studies (45)

TimeframeStudies, this research(%)All Research%
pre-19905 (11.11)18.7374
1990's13 (28.89)18.2507
2000's15 (33.33)29.6817
2010's11 (24.44)24.3611
2020's1 (2.22)2.80

Authors

AuthorsStudies
Lam, JC1
Stevenson, B1
Lee, YG1
Maurer, J1
Patanwala, AE1
Radosevich, JJ1
Maghrabi, K1
Uzun, O1
Kirsh, JA1
Balaji, S1
Von Bergen, NH1
Sanatani, S1
Young, C1
Maruthappu, M1
Wayne, RP1
Leaver, L1
Shah, R1
Deam, AG1
Doshi, D1
Jayawardana, R1
Lindquist, DE1
Rowe, AS1
Heidel, E1
Fleming, T1
Yates, JR1
Cushing, DJ2
Kowey, PR2
Cooper, WD2
Massey, BW1
Gralinski, MR2
Lipicky, RJ2
Dilber, E1
Mutlu, M1
Dilber, B1
Aslan, Y1
Gedik, Y1
Celiker, A1
Marill, KA2
deSouza, IS2
Nishijima, DK2
Senecal, EL1
Setnik, GS2
Stair, TO2
Ruskin, JN2
Ellinor, PT1
Niiya, T1
Litonius, E1
Petäjä, L1
Neuvonen, PJ1
Rosenberg, PH1
Gluck, N1
Fried, M1
Porat, R1
Guglin, M1
Dias Da Silva, VJ1
Gnecchi-Ruscone, T1
Lavelli, B1
Bellina, V1
Manzella, D1
Porta, A1
Malliani, A1
Montano, N1
Aouate, P1
Elbaz, N1
Klug, D1
Lacotte, J1
Raguin, D1
Frank, R1
Lelouche, D1
Dubois-Randé, JL1
Tonet, J1
Fontaine, G1
Cheung, AT1
Weiss, SJ1
Savino, JS1
Levy, WJ1
Augoustides, JG1
Harrington, A1
Gardner, TJ1
MacFadyen, RJ1
Palmer, TJ1
Hisamuddin, K1
Somberg, JC2
Timar, S1
Bailin, SJ1
Lakatos, F1
Haffajee, CI1
Tarjan, J1
Paladino, WP1
Sarosi, I1
Kerin, NZ1
Borbola, J1
Bridges, DE1
Molnar, J2
Canivet, JL1
Yans, T1
Roediger, L1
Radermecker, MA1
Cvetanovic, I1
Ranade, V1
Lessa, MA1
Tibiriçá, E1
Lin, JA1
Borel, CO1
Wang, WB1
Wong, CS1
Yeh, CC1
Yang, CP1
Wu, CT1
Beall, JW1
Mahan, EF1
Blau, AB1
Chockalingam, A1
Tejwani, L1
Aggarwal, K1
Dellsperger, KC1
Turner, S1
Mathews, L1
Pandharipande, P1
Thompson, R1
Buchser, E1
Chiolero, R1
Martin, P1
Freeman, J1
Scheinman, MM3
Levine, JH2
Cannom, DS1
Friehling, T1
Kopelman, HA1
Chilson, DA2
Platia, EV2
Wilber, DJ1
Lee, HS1
Quinn, T1
Boyle, RM1
Massumi, A1
Winkle, RA1
Gomes, A1
Woosley, RL1
Van Mieghem, W1
Tits, G1
Demuynck, K1
Lacquet, L1
Deneffe, G1
Tjandra-Maga, T1
Demedts, M1
Pethig, K1
Wahlers, T1
Tager, S1
Borst, HG1
Dick, W1
Bossaert, L1
Chamberlain, D1
Porterfield, LM1
Mets, B1
Michler, RE1
Delphin, ED1
Oz, MC1
Landry, DW1
Maury, P1
Vuille, C1
Metzger, J1
Veragut, B1
Schoenenberger, I1
Elamly, A1
Chevrolet, JC1
Hilleman, DE1
Spinler, SA1
Hohnloser, SH1
Zabel, M1
Zehender, M1
Meinertz, T1
Just, H1
Mackay, JH1
Walker, IA1
Bethune, DW1
Warren, R1
Vohra, J1
Hunt, D1
Hamer, A1
Geary, VM1
Thaker, UN1
Chalmers, PC1
Sheikh, F1
Helmy, I1
Herre, JM1
Gee, G1
Sharkey, H1
Malone, P1
Sauve, MJ1
Griffin, JC1
Bolińska, H1
Musiał, WJ1
Ruta, J1
Leak, D1
Lee, TH1
Friedman, PL1
Goldman, L1
Stone, PH1
Antman, EM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Using Time-dependent Intravenous Infusions of Amiodarone for Conversions to Sinus Rhythms in Patients With Paroxysmal Atrial Fibrillation[NCT03432663]Phase 460 participants (Actual)Interventional2008-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for amiodarone and Hypotension

ArticleYear
Dynamic left ventricular outflow tract obstruction in acute myocardial infarction with shock: cause, effect, and coincidence.
    Circulation, 2007, Jul-31, Volume: 116, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Algorithms; Amiodarone; Cardiac Catheterization; Diagnosis, Diffe

2007
[Severe flecainide acetate poisoning. Apropos of a case].
    Archives des maladies du coeur et des vaisseaux, 1999, Volume: 92, Issue:2

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Biological Availability; Calcium Gluconate

1999
Conversion of recent-onset atrial fibrillation with intravenous amiodarone: a meta-analysis of randomized controlled trials.
    Pharmacotherapy, 2002, Volume: 22, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Cohort Studies; Humans; Hypote

2002
Efficacy of intravenously administered amiodarone for short-term control of serious arrhythmias.
    Journal of cardiovascular pharmacology, 1992, Volume: 20 Suppl 2

    Topics: Action Potentials; Amiodarone; Arrhythmias, Cardiac; Electrophysiology; Hemodynamics; Humans; Hypote

1992

Trials

5 trials available for amiodarone and Hypotension

ArticleYear
Acute circulatory actions of intravenous amiodarone loading in cardiac surgical patients.
    The Annals of thoracic surgery, 2003, Volume: 76, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Blood Pressure Determination; Cardiac Output; Coronary A

2003
Lack of a hypotensive effect with rapid administration of a new aqueous formulation of intravenous amiodarone.
    The American journal of cardiology, 2004, Mar-01, Volume: 93, Issue:5

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Hypotension; Infusions,

2004
Dose-ranging study of intravenous amiodarone in patients with life-threatening ventricular tachyarrhythmias. The Intravenous Amiodarone Multicenter Investigators Group.
    Circulation, 1995, Dec-01, Volume: 92, Issue:11

    Topics: Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Double-Blind Method; Female; H

1995
Intravenous amiodarone for recurrent sustained hypotensive ventricular tachyarrhythmias. Intravenous Amiodarone Multicenter Trial Group.
    Journal of the American College of Cardiology, 1996, Volume: 27, Issue:1

    Topics: Amiodarone; Analysis of Variance; Anti-Arrhythmia Agents; Bradycardia; Cause of Death; Chi-Square Di

1996
Verapamil as prophylactic treatment for atrial fibrillation after lung operations.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Humans; Hypotension; Incidence

1996

Other Studies

36 other studies available for amiodarone and Hypotension

ArticleYear
Intravenous to Oral Transition of Amiodarone (IOTA): Effect of Various Durations of Overlap on Atrial Fibrillation Recurrence After Cardiothoracic Surgery.
    Journal of cardiovascular pharmacology, 2022, 06-01, Volume: 79, Issue:6

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Humans;

2022
Cardiovascular Collapse with Intravenous Amiodarone in Children: A Multi-Center Retrospective Cohort Study.
    Pediatric cardiology, 2019, Volume: 40, Issue:5

    Topics: Administration, Intravenous; Adolescent; Age Distribution; Amiodarone; Anti-Arrhythmia Agents; Blood

2019
Reversible acute kidney injury requiring haemodialysis five days after starting dronedarone in a stable 71-year-old man at risk of cardiovascular polypharmacy.
    The journal of the Royal College of Physicians of Edinburgh, 2013, Volume: 43, Issue:2

    Topics: Acute Kidney Injury; Aged; Amiodarone; Anti-Arrhythmia Agents; Antihypertensive Agents; Cardiovascul

2013
Wide complex tachycardia in a patient with a family history of sudden death.
    JAMA internal medicine, 2015, Volume: 175, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Death, Sudden; Electrocardiography; Humans; Hypotension; Male; M

2015
Amiodarone-Induced Life-Threatening Refractory Hypotension.
    The American journal of case reports, 2015, Sep-14, Volume: 16

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Hypotension; Male

2015
Evaluation of the Hemodynamic Effects of Intravenous Amiodarone Formulations During the Maintenance Phase Infusion.
    The Annals of pharmacotherapy, 2015, Volume: 49, Issue:12

    Topics: Aged; Aged, 80 and over; Amiodarone; Antihypertensive Agents; Benzyl Alcohols; Cyclodextrins; Dosage

2015
PM101: a cyclodextrin-based intravenous formulation of amiodarone devoid of adverse hemodynamic effects.
    European journal of pharmacology, 2009, Apr-01, Volume: 607, Issue:1-3

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzyl Alcohol; beta-Cyclodextrins; Blood Pressure; Car

2009
The hypotensive effect of intravenous amiodarone is sustained throughout the maintenance infusion period.
    Clinical and experimental pharmacology & physiology, 2010, Volume: 37, Issue:3

    Topics: Amiodarone; Animals; Blood Pressure; Dogs; Female; Heart Rate; Hypotension; Infusions, Intravenous;

2010
Intravenous amiodarone used alone or in combination with digoxin for life-threatening supraventricular tachyarrhythmia in neonates and small infants.
    Pediatric emergency care, 2010, Volume: 26, Issue:2

    Topics: Adenosine; Amiodarone; Anti-Arrhythmia Agents; Atrial Flutter; Digoxin; Drug Evaluation; Drug Therap

2010
Amiodarone or procainamide for the termination of sustained stable ventricular tachycardia: an historical multicenter comparison.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2010, Volume: 17, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cohort Studies; Drug Administration Schedule; Electrocardi

2010
Intravenous lipid emulsion sequesters amiodarone in plasma and eliminates its hypotensive action in pigs.
    Annals of emergency medicine, 2010, Volume: 56, Issue:4

    Topics: Amiodarone; Animals; Blood Pressure; Fat Emulsions, Intravenous; Female; Heart Rate; Hypotension; Ma

2010
Acute amiodarone liver toxicity likely due to ischemic hepatitis.
    The Israel Medical Association journal : IMAJ, 2011, Volume: 13, Issue:12

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Chemical and Drug Induced Liver Injury; Female; He

2011
Occam's razor and ischemic hepatitis.
    The Israel Medical Association journal : IMAJ, 2012, Volume: 14, Issue:6

    Topics: Amiodarone; Chemical and Drug Induced Liver Injury; Female; Hepatitis; Humans; Hypotension; Ischemia

2012
Opposite effects of iv amiodarone on cardiovascular vagal and sympathetic efferent activities in rats.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2002, Volume: 283, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Atropine; Autonomic Fibers, Preganglionic; Baroreflex;

2002
[Atrial flutter with 1/1 nodo-ventricular conduction with amiodarone. From physiopathology to diagnosis].
    Archives des maladies du coeur et des vaisseaux, 2002, Volume: 95, Issue:12

    Topics: Administration, Oral; Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial

2002
Rapidly fatal acute amiodarone hepatitis occurring in the context of multiple organ failure.
    International journal of cardiology, 2003, Volume: 91, Issue:2-3

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomyopathy, Dilated; Chemical and Drug

2003
Left atrial thrombus formation early after mitral valve replacement.
    Journal of cardiothoracic and vascular anesthesia, 2004, Volume: 18, Issue:5

    Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Atrial Fibrillation; Cardiac Output, Low; Echoca

2004
Comparative effects of rapid bolus administration of aqueous amiodarone versus 10-minute cordarone I.v. infusion on mean arterial blood pressure in conscious dogs.
    Cardiovascular drugs and therapy, 2004, Volume: 18, Issue:5

    Topics: Amiodarone; Animals; Blood Pressure; Chemistry, Pharmaceutical; Dogs; Female; Hypotension; Infusions

2004
Acute cardiodepressant effects induced by bolus intravenous administration of amiodarone in rabbits.
    Fundamental & clinical pharmacology, 2005, Volume: 19, Issue:2

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Pressure; Cardiac Output; Female; Hypotension; In

2005
Amiodarone is poorly effective for the acute termination of ventricular tachycardia.
    Annals of emergency medicine, 2006, Volume: 47, Issue:3

    Topics: Aged; Aged, 80 and over; Amiodarone; Combined Modality Therapy; Dose-Response Relationship, Drug; El

2006
Anesthetic management of an AAI pacemaker patient with paroxysmal atrial fibrillation during colorectal surgery.
    Journal of clinical anesthesia, 2006, Volume: 18, Issue:5

    Topics: Aged; Amiodarone; Anesthesia, General; Anti-Arrhythmia Agents; Atrial Fibrillation; Atropine; Bradyc

2006
Use of amiodarone in a patient with a shellfish allergy.
    Southern medical journal, 2007, Volume: 100, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Follow-Up Studies; Food Hypersensitiv

2007
Dolasetron-induced torsades de pointes.
    Journal of clinical anesthesia, 2007, Volume: 19, Issue:8

    Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Antiemetics; Cardiopulmonary Resusc

2007
Amiodarone-induced haemodynamic complications during anaesthesia.
    Anaesthesia, 1983, Volume: 38, Issue:10

    Topics: Aged; Amiodarone; Benzofurans; Bradycardia; Female; Humans; Hypotension; Intraoperative Complication

1983
Safety of thrombolytic treatment in patients with central venous cannulation.
    British heart journal, 1995, Volume: 73, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Catheterization, Central Venous; Contraindications; Fema

1995
Perioperative complications in combined aortic valve replacement and extraanatomic ascending-descending bypass.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Aorta; Aorta, Thoracic; Aortic Coarctation; Aortic Valve; Aortic

1996
European guidelines on resuscitation.
    Lancet (London, England), 1996, Jun-01, Volume: 347, Issue:9014

    Topics: Amiodarone; Anti-Arrhythmia Agents; Europe; Humans; Hypotension; Practice Guidelines as Topic; Resus

1996
This drug needs close monitoring.
    RN, 1996, Volume: 59, Issue:7

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Monitoring; Humans; Hypotension; Male; Nursing Assess

1996
Refractory vasodilation after cardiopulmonary bypass for heart transplantation in recipients on combined amiodarone and angiotensin-converting enzyme inhibitor therapy: a role for vasopressin administration.
    Journal of cardiothoracic and vascular anesthesia, 1998, Volume: 12, Issue:3

    Topics: Aged; Aged, 80 and over; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Cardi

1998
Amiodarone and anaesthesia: concurrent therapy with ACE inhibitors--an additional cause for concern?
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1991, Volume: 38, Issue:5

    Topics: Adult; Amiodarone; Anesthesia, Intravenous; Enalapril; Fentanyl; Humans; Hypotension; Male; Midazola

1991
Serious interactions of sotalol with amiodarone and flecainide.
    The Medical journal of Australia, 1990, Mar-05, Volume: 152, Issue:5

    Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Drug Administration Schedule; Drug Interactions; Drug Therap

1990
The use of angiotensin II to treat profound hypotension in a patient taking amiodarone.
    Journal of cardiothoracic anesthesia, 1990, Volume: 4, Issue:3

    Topics: Amiodarone; Angiotensin II; Blood Pressure; Cardiac Output; Cardiopulmonary Bypass; Humans; Hypotens

1990
Use of intravenous amiodarone for emergency treatment of life-threatening ventricular arrhythmias.
    Journal of the American College of Cardiology, 1988, Volume: 12, Issue:4

    Topics: Amiodarone; Arrhythmias, Cardiac; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Emer

1988
[Complications after oral and intravenous administration of amiodarone (cordaron)].
    Wiadomosci lekarskie (Warsaw, Poland : 1960), 1986, Oct-01, Volume: 39, Issue:19

    Topics: Administration, Oral; Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Female; Humans; Hyp

1986
Intravenous amiodarone in the treatment of refractory life-threatening cardiac arrhythmias in the critically ill patient.
    American heart journal, 1986, Volume: 111, Issue:3

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Blood Pressure; Dopamine; Electrocardiog

1986
Sinus arrest and hypotension with combined amiodarone-diltiazem therapy.
    American heart journal, 1985, Volume: 109, Issue:1

    Topics: Amiodarone; Benzazepines; Benzofurans; Diltiazem; Drug Interactions; Drug Therapy, Combination; Fema

1985