Page last updated: 2024-10-22

amiodarone and Hyponatremia

amiodarone has been researched along with Hyponatremia in 11 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Hyponatremia: Deficiency of sodium in the blood; salt depletion. (Dorland, 27th ed)

Research Excerpts

ExcerptRelevanceReference
"We describe an elderly woman who presented with significant hyponatremia caused by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during therapy with amiodarone."7.70Hyponatremia during therapy with amiodarone. ( Odeh, M; Oliven, A; Schiff, E, 1999)
"Amiodarone is an antiarrhythmic drug belonging to Vaughan-Williams Class III with additional Class IV effects, which is known to cause many adverse drug reactions (ADRs) necessitating close monitoring."5.91Amiodarone-Induced Hyponatremia in An Elderly Patient: A Rare Case Report. ( Chalasani, SH; Jodiya, A; Mahadevappa, M; Pereira, P; Ramesh, M; Syed, JM, 2023)
"Amiodarone was discontinued based on a case report suggesting that this drug can cause SIADH-induced hyponatremia."5.31Syndrome of inappropriate antidiuretic hormone-induced hyponatremia associated with amiodarone. ( Kasiar, JB; Patel, GP, 2002)
"We describe a case of amiodarone induced hyponatremia consistent with the syndrome of inappropriate antidiuretic hormone (SIADH) that developed during amiodarone loading, similar to three prior reports."3.72Syndrome of inappropriate antidiuretic hormone secretion induced by amiodarone therapy. ( Aslam, MK; Gnaim, C; Kowal, RC; Kutnick, J; McGuire, DK, 2004)
"We report on two elderly cases that developed hyponatremia caused by SIADH occurring during the initial loading period of amiodarone therapy."3.71Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induced by amiodarone: a report on two cases. ( Ikegami, H; Kasanuki, H; Nirei, T; Shiga, T; Tsushima, T, 2002)
"We describe an elderly woman who presented with significant hyponatremia caused by the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) during therapy with amiodarone."3.70Hyponatremia during therapy with amiodarone. ( Odeh, M; Oliven, A; Schiff, E, 1999)
"Amiodarone is an antiarrhythmic drug belonging to Vaughan-Williams Class III with additional Class IV effects, which is known to cause many adverse drug reactions (ADRs) necessitating close monitoring."1.91Amiodarone-Induced Hyponatremia in An Elderly Patient: A Rare Case Report. ( Chalasani, SH; Jodiya, A; Mahadevappa, M; Pereira, P; Ramesh, M; Syed, JM, 2023)
"Background Hyponatremia has been known as an important predictor of clinical outcomes in patients with heart failure (HF)."1.43Patient and medication-related factors associated with hospital-acquired hyponatremia in patients hospitalized from heart failure. ( Ball, PA; Morrissey, H; Saepudin, S, 2016)
"Amiodarone was discontinued based on a case report suggesting that this drug can cause SIADH-induced hyponatremia."1.31Syndrome of inappropriate antidiuretic hormone-induced hyponatremia associated with amiodarone. ( Kasiar, JB; Patel, GP, 2002)
"The presence of ventricular arrhythmias was related to the severity of left ventricular dysfunction, exercise intolerance, and neurohormonal activation, suggesting that such arrhythmias are multifactorial in origin and may not simply be related to electrolyte abnormalities."1.27Relation of arrhythmias and electrolyte abnormalities to survival in patients with severe chronic heart failure. ( Cleland, JG; Dargie, HJ; East, BW; Ford, I; Inglis, CG; Leckie, BJ, 1987)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's1 (9.09)18.2507
2000's5 (45.45)29.6817
2010's2 (18.18)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Mahadevappa, M1
Jodiya, A1
Chalasani, SH1
Syed, JM1
Ramesh, M1
Pereira, P1
Qi, A1
Moscona, JC1
Reed, J1
Le Jemtel, TH1
Nakamura, M1
Sunagawa, O1
Kugai, T1
Kinugawa, K1
Saepudin, S1
Ball, PA1
Morrissey, H1
Aslam, MK1
Gnaim, C1
Kutnick, J1
Kowal, RC1
McGuire, DK1
Maheshwari, M1
Baid, JC1
Vijayvergia, A1
Shavit, E1
Sherer, Y1
Odeh, M1
Schiff, E1
Oliven, A1
Ikegami, H1
Shiga, T1
Tsushima, T1
Nirei, T1
Kasanuki, H1
Patel, GP1
Kasiar, JB1
Dargie, HJ1
Cleland, JG1
Leckie, BJ1
Inglis, CG1
East, BW1
Ford, I1

Other Studies

11 other studies available for amiodarone and Hyponatremia

ArticleYear
Amiodarone-Induced Hyponatremia in An Elderly Patient: A Rare Case Report.
    Journal of pharmacy practice, 2023, Volume: 36, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug-Related Side Effects and Adverse Reactions; Female; H

2023
Altered Mental Status and Hyponatremia After 20 Hours of Amiodarone Therapy.
    Texas Heart Institute journal, 2020, 06-01, Volume: 47, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Female; Follow-Up Studies; Humans; Hy

2020
Amiodarone-Induced Hyponatremia Masked by Tolvaptan in a Patient with an Implantable Left Ventricular Assist Device.
    International heart journal, 2017, Dec-12, Volume: 58, Issue:6

    Topics: Adult; Amiodarone; Antidiuretic Hormone Receptor Antagonists; Benzazepines; Delirium; Heart Failure;

2017
Patient and medication-related factors associated with hospital-acquired hyponatremia in patients hospitalized from heart failure.
    International journal of clinical pharmacy, 2016, Volume: 38, Issue:4

    Topics: Amiodarone; Ascites; Case-Control Studies; Female; Heart Failure; Hospital Mortality; Humans; Hypona

2016
Syndrome of inappropriate antidiuretic hormone secretion induced by amiodarone therapy.
    Pacing and clinical electrophysiology : PACE, 2004, Volume: 27, Issue:6 Pt 1

    Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Diagnos

2004
Amiodarone related rare toxicity in a burn patient.
    Burns : journal of the International Society for Burn Injuries, 2007, Volume: 33, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Burns; Humans; Hyponatremia; Male; Pl

2007
Hyponatremia induced by amiodarone therapy.
    The Israel Medical Association journal : IMAJ, 2007, Volume: 9, Issue:7

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Hyponatremia; Ma

2007
Hyponatremia during therapy with amiodarone.
    Archives of internal medicine, 1999, Nov-22, Volume: 159, Issue:21

    Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Middle

1999
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) induced by amiodarone: a report on two cases.
    Journal of cardiovascular pharmacology and therapeutics, 2002, Volume: 7, Issue:1

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Humans; Hyponatremia; Inappropriate ADH

2002
Syndrome of inappropriate antidiuretic hormone-induced hyponatremia associated with amiodarone.
    Pharmacotherapy, 2002, Volume: 22, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; So

2002
Relation of arrhythmias and electrolyte abnormalities to survival in patients with severe chronic heart failure.
    Circulation, 1987, Volume: 75, Issue:5 Pt 2

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Captopril; Enalapril; Exercise Test; Female; Heart Fa

1987