amiodarone has been researched along with Hypokalemia in 13 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Hypokalemia: Abnormally low potassium concentration in the blood. It may result from potassium loss by renal secretion or by the gastrointestinal route, as by vomiting or diarrhea. It may be manifested clinically by neuromuscular disorders ranging from weakness to paralysis, by electrocardiographic abnormalities (depression of the T wave and elevation of the U wave), by renal disease, and by gastrointestinal disorders. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe the appearance of long QT interval and polymorphous ventricular tachycardia in a patient treated with amiodarone who presented with hypokalemia secondary to chronic diuretic therapy." | 7.67 | Amiodarone and hypokalemia. A dangerous combination. ( Corres Peiretti, MA; Moro, C; Romero, J, 1986) |
| " In the first case, the drugs venlafaxine, amiodarone and domperidone may have contributed to QT interval prolongation in a patient with hypokalemia and hypomagnesaemia." | 3.76 | Multifactorial QT interval prolongation. ( Baranchuk, A; Digby, G; Machaalany, J; Malik, P; Methot, M; Redfearn, D; Simpson, CS, 2010) |
| "Recurrent atypical ventricular tachycardia, with a long QT interval, was documented in a 56-year-old patient 16 days after discontinuing amiodarone 200 mg and 400 mg on alternate days." | 3.67 | Torsade de pointes after amiodarone withdrawal; effects of mild hypokalaemia on repolarization. ( Forfar, JC; Gribbin, B, 1984) |
| "We describe the appearance of long QT interval and polymorphous ventricular tachycardia in a patient treated with amiodarone who presented with hypokalemia secondary to chronic diuretic therapy." | 3.67 | Amiodarone and hypokalemia. A dangerous combination. ( Corres Peiretti, MA; Moro, C; Romero, J, 1986) |
| "Caffeine is a natural alkaloid methylxanthine that is found in various plants such as coffee or tea." | 1.36 | A case of fatal caffeine poisoning. ( Knudsen, K; Rudolph, T, 2010) |
| "The same changes and cardiac arrhythmias are characteristic of second-degree hypopolarization." | 1.33 | Simulation of cardiac hypopolarization arrhythmias and evaluation of cardiomyocyte membrane hypopolarization in experimental animals. ( Lipnitskii, TN; Moroz, VM, 2006) |
| "The potential antiarrhythmic and electrophysiological effects of prolonged oral dosing with amiodarone (20 mg/kg/day) or disopyramide (25 or 50 mg/kg b." | 1.27 | Effects of diet-induced hypokalaemia on the antiarrhythmic and electrophysiological actions of prolonged oral treatment with either amiodarone or disopyramide in the anaesthetised rat. ( Hope, FG; Marshall, RJ; Winslow, E, 1987) |
| "The presence of ventricular arrhythmias was related to the severity of left ventricular dysfunction, exercise intolerance, and neurohormonal activation, suggesting that such arrhythmias are multifactorial in origin and may not simply be related to electrolyte abnormalities." | 1.27 | Relation of arrhythmias and electrolyte abnormalities to survival in patients with severe chronic heart failure. ( Cleland, JG; Dargie, HJ; East, BW; Ford, I; Inglis, CG; Leckie, BJ, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (61.54) | 18.7374 |
| 1990's | 2 (15.38) | 18.2507 |
| 2000's | 1 (7.69) | 29.6817 |
| 2010's | 2 (15.38) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rudolph, T | 1 |
| Knudsen, K | 1 |
| Digby, G | 1 |
| Machaalany, J | 1 |
| Malik, P | 1 |
| Methot, M | 1 |
| Simpson, CS | 1 |
| Redfearn, D | 1 |
| Baranchuk, A | 1 |
| Moroz, VM | 1 |
| Lipnitskii, TN | 1 |
| Santinelli, V | 2 |
| Chiariello, M | 2 |
| Santinelli, C | 1 |
| Condorelli, M | 2 |
| Forfar, JC | 1 |
| Gribbin, B | 1 |
| Bajaj, BP | 1 |
| Baig, MW | 1 |
| Perrins, EJ | 1 |
| Alvarez, A | 1 |
| Sáenz, L | 1 |
| Oliveras, C | 1 |
| Llordes, M | 1 |
| Winslow, E | 1 |
| Marshall, RJ | 1 |
| Hope, FG | 1 |
| Rudnick, L | 1 |
| Ovsyscher, IA | 1 |
| Dargie, HJ | 1 |
| Cleland, JG | 1 |
| Leckie, BJ | 1 |
| Inglis, CG | 1 |
| East, BW | 1 |
| Ford, I | 1 |
| González, R | 1 |
| Mercadal, E | 1 |
| Alburquerque, J | 1 |
| Martínez, A | 1 |
| Moro, C | 1 |
| Romero, J | 1 |
| Corres Peiretti, MA | 1 |
13 other studies available for amiodarone and Hypokalemia
| Article | Year |
|---|---|
A case of fatal caffeine poisoning.
Topics: Amiodarone; Anti-Arrhythmia Agents; Caffeine; Cardiopulmonary Resuscitation; Central Nervous System | 2010 |
Multifactorial QT interval prolongation.
Topics: Alcoholism; Amiodarone; Antipsychotic Agents; Arrhythmias, Cardiac; Biomarkers; Citalopram; Cyclohex | 2010 |
Simulation of cardiac hypopolarization arrhythmias and evaluation of cardiomyocyte membrane hypopolarization in experimental animals.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrioventricular Node; Blood Pres | 2006 |
Ventricular tachyarrhythmias complicating amiodarone therapy in the presence of hypokalemia.
Topics: Amiodarone; Benzofurans; Female; Humans; Hypokalemia; Middle Aged; Tachycardia | 1984 |
Torsade de pointes after amiodarone withdrawal; effects of mild hypokalaemia on repolarization.
Topics: Amiodarone; Benzofurans; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Female; Human | 1984 |
Amiodarone-induced torsades de pointes: the possible facilitatory role of digoxin.
Topics: Administration, Oral; Aged; Amiodarone; Digoxin; Drug Interactions; Electrocardiography; Female; Hum | 1991 |
[Electrocardiographic changes caused by ionic disorders and drugs].
Topics: Adrenergic beta-Antagonists; Amiodarone; Digitalis; Education, Medical, Continuing; Electrocardiogra | 1990 |
Effects of diet-induced hypokalaemia on the antiarrhythmic and electrophysiological actions of prolonged oral treatment with either amiodarone or disopyramide in the anaesthetised rat.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Diet; Disopyramid | 1987 |
Polymorphous ventricular tachycardia (PVT)
Topics: Amiodarone; Benzofurans; Electrocardiography; Humans; Hypokalemia; Tachycardia | 1985 |
Relation of arrhythmias and electrolyte abnormalities to survival in patients with severe chronic heart failure.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Captopril; Enalapril; Exercise Test; Female; Heart Fa | 1987 |
[Torsade de pointes: clinical experience of 9 patients].
Topics: Adult; Aged; Amiodarone; Coronary Disease; Electrocardiography; Female; Humans; Hypokalemia; Isoprot | 1988 |
Amiodarone and hypokalemia. A dangerous combination.
Topics: Amiodarone; Female; Humans; Hypokalemia; Middle Aged; Tachycardia | 1986 |
Chronic amiodarone therapy and hypokalemia.
Topics: Amiodarone; Benzofurans; Humans; Hypokalemia; Tachycardia | 1985 |