Page last updated: 2024-10-22

amiodarone and Hypermelanosis

amiodarone has been researched along with Hypermelanosis in 21 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Research Excerpts

ExcerptRelevanceReference
"For decades, the photodistributed blue-gray skin hyperpigmentation observed after amiodarone therapy was presumably attributed to dermal lipofuscinosis."7.74Photodistribution of blue-gray hyperpigmentation after amiodarone treatment: molecular characterization of amiodarone in the skin. ( Alvarez, F; Ammoury, A; Bazex, J; Chouini-Lalanne, N; Lamant, L; Launay, F; Marguery, MC; Michaud, S; Paul, C; Prost-Squarcioni, C, 2008)
"We describe three cases of hyperpigmentation after using amiodarone in elder men."4.85[Skin adverse effects of amiodarone]. ( Jedlicková, H; Vasků, V; Zgazarová, S, 2009)
"For decades, the photodistributed blue-gray skin hyperpigmentation observed after amiodarone therapy was presumably attributed to dermal lipofuscinosis."3.74Photodistribution of blue-gray hyperpigmentation after amiodarone treatment: molecular characterization of amiodarone in the skin. ( Alvarez, F; Ammoury, A; Bazex, J; Chouini-Lalanne, N; Lamant, L; Launay, F; Marguery, MC; Michaud, S; Paul, C; Prost-Squarcioni, C, 2008)
"A 79-year-old man developed a blue-greyish facial hyperpigmentation after amiodarone administration over 4 years."3.74[Diagnostic image (365). A man with facial hyperpigmentation]. ( Frank, J; Nellen, RG, 2008)
"Amiodarone is a antiarrhythmic drug with many side-effects which include also the induction of photosensitivity and the development of greyish-blue pigmentations on the skin exposed to light."1.29Skin side-effects of amiodarone therapy. ( Ettler, K; Gregor, J; Nozi cková, M; Pidrman, V; Subrtová, D, 1993)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (9.52)18.2507
2000's10 (47.62)29.6817
2010's8 (38.10)24.3611
2020's1 (4.76)2.80

Authors

AuthorsStudies
Gülderen, I1
Koushk-Jalali, B1
Kreuter, A1
Sayk, F1
Grusnick, HM1
Weil, J1
Ul Rehman, S1
Siddiqui, N1
Khan, NS1
Sobia, R1
Assaly, R1
Jaworski, K1
Walecka, I1
Rudnicka, L1
Gnatowski, M1
Kosior, DA1
Ünal, E1
Perkin, P1
Konca Değertekin, C1
Ergül, G1
Said, DG1
Ho, S1
Mathew, M1
Alomar, T1
Dua, HS1
e Silva, LP1
Luís, F1
Cabrera, H1
Zgazarová, S1
Jedlicková, H1
Vasků, V1
Stähli, BE1
Schwab, S1
Bagheri, S1
Eisen, D1
Michalski, T1
Bernstein, EF1
Dissemond, J1
Franckson, T1
Fitz, G1
Hillen, U1
Goos, M1
Yones, SS1
O'Donoghue, NB1
Palmer, RA1
Menagé, Hdu P1
Hawk, JL1
Wiper, A1
Roberts, DH1
Schmitt, M1
Ammoury, A1
Michaud, S1
Paul, C1
Prost-Squarcioni, C1
Alvarez, F1
Lamant, L1
Launay, F1
Bazex, J1
Chouini-Lalanne, N1
Marguery, MC1
Nellen, RG1
Frank, J1
Ettler, K1
Gregor, J1
Pidrman, V1
Subrtová, D1
Nozi cková, M1
Ameneiros Lago, E1
González Moraleja, J1
Carballada Rico, C1
Sesma Sánchez, P1
Haas, N1
Schadendorf, D1
Hermes, B1
Henz, BM1
Dereure, O1

Reviews

3 reviews available for amiodarone and Hypermelanosis

ArticleYear
Cutaneous adverse reactions of amiodarone.
    Medical science monitor : international medical journal of experimental and clinical research, 2014, Nov-21, Volume: 20

    Topics: Amiodarone; Dermatitis, Photoallergic; Dermatitis, Phototoxic; Humans; Hyperpigmentation; Skin

2014
[Skin adverse effects of amiodarone].
    Vnitrni lekarstvi, 2009, Volume: 55, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Eruptions; Humans; Hyperpigmentation; Male; Middle Ag

2009
Drug-induced skin pigmentation. Epidemiology, diagnosis and treatment.
    American journal of clinical dermatology, 2001, Volume: 2, Issue:4

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Antimalari

2001

Other Studies

18 other studies available for amiodarone and Hypermelanosis

ArticleYear
[An 80-year old man with a bluish-grey facial coloration].
    Deutsche medizinische Wochenschrift (1946), 2021, Volume: 146, Issue:7

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Face; Humans; Hyperp

2021
Oxygen-Resistant "Cyanosis" After Sun Exposure.
    Deutsches Arzteblatt international, 2018, Feb-09, Volume: 115, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Cyanosis; Erythema; Humans; Hyperpigmentation; Male; Middle Aged

2018
Multisystem side effects of amiodarone.
    The American journal of the medical sciences, 2015, Volume: 349, Issue:5

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injury; Fac

2015
Hyperpigmentation on face and arms and thyrotoxicosis induced by amiodarone treatment.
    Cutaneous and ocular toxicology, 2017, Volume: 36, Issue:1

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arm; Arrhythmias, Cardiac; Face; Humans; Hyperpigmentation

2017
Rings around cones.
    The British journal of ophthalmology, 2009, Volume: 93, Issue:4

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Corneal Diseases; Corneal Topography; Diagnosis, Different

2009
Facial hyperpigmentation. amiodarone-induced hyperpigmentation.
    American family physician, 2008, Dec-01, Volume: 78, Issue:11

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Diagnosis, Differential; Facial Derma

2008
Amiodarone-induced skin hyperpigmentation.
    QJM : monthly journal of the Association of Physicians, 2011, Volume: 104, Issue:8

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Face; Hand; Humans; Hyperpigmentation

2011
Long-pulse neodymium-doped yttrium aluminum garnet laser treatment improves amiodarone-induced hyperpigmentation.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2011, Volume: 37, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Face; Humans; Hyperpigmentation; Lasers, Solid-State; Low-

2011
[79-year-old patient with dyspnoea and blue skin colour].
    Deutsche medizinische Wochenschrift (1946), 2011, Volume: 136, Issue:37

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Disease; Cyanosis; Dermatitis, Photoallergic; Dia

2011
Q-switched laser treatment of amiodarone pigmentation.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:11

    Topics: Amiodarone; Face; Follow-Up Studies; Humans; Hyperpigmentation; Laser Therapy; Lasers, Solid-State;

2011
[Hyperpigmentation of the face].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2003, Volume: 54, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Diagnosis, Differential; Facial Dermatoses; Humans

2003
Persistent severe amiodarone-induced photosensitivity.
    Clinical and experimental dermatology, 2005, Volume: 30, Issue:5

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Facial Dermatoses; Female; Humans; Hyperpigmentation; Phot

2005
Amiodarone-induced skin pigmentation: Q-switched laser therapy, an effective treatment option.
    Heart (British Cardiac Society), 2007, Volume: 93, Issue:1

    Topics: Amiodarone; Drug Eruptions; Facial Dermatoses; Humans; Hyperpigmentation; Laser Therapy; Male; Middl

2007
Photodistribution of blue-gray hyperpigmentation after amiodarone treatment: molecular characterization of amiodarone in the skin.
    Archives of dermatology, 2008, Volume: 144, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Biopsy, Needle; Chromatography, High Pressure Liquid; Facial Der

2008
[Diagnostic image (365). A man with facial hyperpigmentation].
    Nederlands tijdschrift voor geneeskunde, 2008, Mar-15, Volume: 152, Issue:11

    Topics: Aged; Amiodarone; Cardiovascular Agents; Humans; Hyperpigmentation; Male

2008
Skin side-effects of amiodarone therapy.
    Sbornik vedeckych praci Lekarske fakulty Karlovy university v Hradci Kralove, 1993, Volume: 36, Issue:4-5

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Drug Eruptions; Humans; Hyperpig

1993
[Medicine in images. A special "suntan" and bradycardia].
    Revista clinica espanola, 1998, Volume: 198, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Corneal Diseases; Dermatitis, Photoal

1998
Hypomelanosis due to block of melanosomal maturation in amiodarone-induced hyperpigmentation.
    Archives of dermatology, 2001, Volume: 137, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Biopsy; Facial Dermatoses; Humans; Hyperpigmentation; Male; Mela

2001