amiodarone has been researched along with Hepatocellular Carcinoma in 17 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The results of this study suggest that lipiodol transarterial chemoembolisation with anthracycline and amiodarone was safe but did not increase survival compared with lipiodol transarterial chemoembolisation with anthracycline alone in patients with hepatocellular carcinoma." | 9.15 | Randomised controlled trial of lipiodol transarterial chemoembolisation with or without amiodarone for unresectable hepatocellular carcinoma. ( Bedenne, L; Bonnetain, F; Boulin, M; Cercueil, JP; Chauffert, B; Ciboulet, A; Gagnaire, A; Guiu, B; Hillon, P; Jouve, JL; Krause, D; Lepage, C; Maillard, E; Minello, A, 2011) |
| "Amiodarone is a multidrug resistance inhibitor." | 5.32 | [Sustained clinical response of large hepatocellular carcinoma after chemoembolization with pirarubicin, amiodarone and Lipiodol]. ( Bedenne, L; Cercueil, JP; Chauffert, B; Ferrant, E; Flesch, M; Isambert, N; Jouve, JL; Krause, D, 2004) |
| "The results of this study suggest that lipiodol transarterial chemoembolisation with anthracycline and amiodarone was safe but did not increase survival compared with lipiodol transarterial chemoembolisation with anthracycline alone in patients with hepatocellular carcinoma." | 5.15 | Randomised controlled trial of lipiodol transarterial chemoembolisation with or without amiodarone for unresectable hepatocellular carcinoma. ( Bedenne, L; Bonnetain, F; Boulin, M; Cercueil, JP; Chauffert, B; Ciboulet, A; Gagnaire, A; Guiu, B; Hillon, P; Jouve, JL; Krause, D; Lepage, C; Maillard, E; Minello, A, 2011) |
| "The prediction of drug-drug interactions mediated by the induction or inhibition of cytochrome P450 enzymes is of great relevance in the development of new drugs." | 1.40 | HepaRG cell line as an in vitro model for screening drug-drug interactions mediated by metabolic induction: amiodarone used as a model substance. ( Alves, G; Falcão, A; Ferreira, A; Rodrigues, M; Silvestre, S, 2014) |
| "Amiodarone is a multidrug resistance inhibitor." | 1.32 | [Sustained clinical response of large hepatocellular carcinoma after chemoembolization with pirarubicin, amiodarone and Lipiodol]. ( Bedenne, L; Cercueil, JP; Chauffert, B; Ferrant, E; Flesch, M; Isambert, N; Jouve, JL; Krause, D, 2004) |
| "Amiodarone and EMD 21388 were without effect both in cytosol and nuclear extract." | 1.29 | Drug competition for intracellular triiodothyronine-binding sites. ( Barlow, JW; Curtis, AJ; Loidl, NM; Raggatt, LE; Stockigt, JR; Topliss, DJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (11.76) | 18.7374 |
| 1990's | 3 (17.65) | 18.2507 |
| 2000's | 5 (29.41) | 29.6817 |
| 2010's | 7 (41.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, ST | 1 |
| Hsu, WF | 1 |
| Huang, HS | 1 |
| Yen, JH | 1 |
| Lin, MC | 1 |
| Peng, CY | 1 |
| Yen, HR | 1 |
| Lan, SH | 1 |
| Wu, SY | 1 |
| Zuchini, R | 1 |
| Lin, XZ | 1 |
| Su, IJ | 1 |
| Tsai, TF | 1 |
| Lin, YJ | 1 |
| Wu, CT | 1 |
| Liu, HS | 1 |
| Ferreira, A | 1 |
| Rodrigues, M | 1 |
| Silvestre, S | 1 |
| Falcão, A | 1 |
| Alves, G | 1 |
| Maimone, S | 1 |
| Filomia, R | 1 |
| Saitta, C | 1 |
| Raimondo, G | 1 |
| Squadrito, G | 1 |
| Guiu, B | 2 |
| Colin, C | 1 |
| Cercueil, JP | 4 |
| Loffroy, R | 1 |
| Guiu, S | 1 |
| Ferrant, E | 2 |
| Jouve, JL | 3 |
| Bonnetain, F | 2 |
| Boulin, M | 2 |
| Ghiringhelli, F | 1 |
| Minello, A | 2 |
| Hillon, P | 3 |
| Bedenne, L | 6 |
| Krause, D | 4 |
| Chauffert, B | 6 |
| Niklas, J | 1 |
| Noor, F | 1 |
| Heinzle, E | 1 |
| Anthérieu, S | 1 |
| Rogue, A | 1 |
| Fromenty, B | 1 |
| Guillouzo, A | 2 |
| Robin, MA | 1 |
| von Vital, JM | 1 |
| Karachristos, A | 1 |
| Singhal, A | 1 |
| Thomas, R | 1 |
| Jain, A | 1 |
| Ciboulet, A | 1 |
| Maillard, E | 1 |
| Gagnaire, A | 1 |
| Lepage, C | 1 |
| Isambert, N | 2 |
| Flesch, M | 1 |
| Aninat, C | 1 |
| Piton, A | 1 |
| Glaise, D | 1 |
| Le Charpentier, T | 1 |
| Langouët, S | 1 |
| Morel, F | 1 |
| Guguen-Guillouzo, C | 1 |
| Barlow, JW | 1 |
| Curtis, AJ | 1 |
| Raggatt, LE | 1 |
| Loidl, NM | 1 |
| Topliss, DJ | 1 |
| Stockigt, JR | 1 |
| Bakker, O | 1 |
| Hudig, F | 1 |
| Meijssen, S | 1 |
| Wiersinga, WM | 1 |
| Favoulet, P | 1 |
| Faure, P | 1 |
| Osmak, L | 1 |
| Beltramo, JL | 1 |
| Cognet, F | 1 |
| Seitz, JF | 1 |
| Renard, P | 1 |
| Conroy, T | 1 |
| Rougier, P | 1 |
| Lorcerie, B | 1 |
| Faivre, J | 1 |
| Klepping, C | 1 |
| Martin, F | 1 |
| Adler, M | 1 |
| Ros, P | 1 |
| Cremer, M | 1 |
| Quiriny, M | 1 |
| Henry, JP | 1 |
| Lecocq, E | 1 |
1 review available for amiodarone and Hepatocellular Carcinoma
| Article | Year |
|---|---|
[Drug-induced hepatic lesions].
Topics: Adenoma; Amiodarone; Amphetamines; Antineoplastic Agents; Budd-Chiari Syndrome; Carcinoma, Hepatocel | 1986 |
2 trials available for amiodarone and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Randomised controlled trial of lipiodol transarterial chemoembolisation with or without amiodarone for unresectable hepatocellular carcinoma.
Topics: Adult; Aged; Amiodarone; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; | 2011 |
Phase II evaluation of doxorubicin plus amiodarone in advanced hepatocarcinoma.
Topics: Adult; Aged; Amiodarone; Carcinoma, Hepatocellular; Doxorubicin; Drug Evaluation; Drug Therapy, Comb | 1991 |
14 other studies available for amiodarone and Hepatocellular Carcinoma
| Article | Year |
|---|---|
Improved Survival in Hepatocellular Carcinoma Patients with Cardiac Arrhythmia by Amiodarone Treatment through Autophagy.
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Autophagy; Carcinoma, Hepatocellular; Cell Survival; Female; | 2019 |
Autophagy suppresses tumorigenesis of hepatitis B virus-associated hepatocellular carcinoma through degradation of microRNA-224.
Topics: Amiodarone; Animals; Autophagy; Carcinogenesis; Carcinoma, Hepatocellular; Disease Models, Animal; D | 2014 |
HepaRG cell line as an in vitro model for screening drug-drug interactions mediated by metabolic induction: amiodarone used as a model substance.
Topics: Amiodarone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytochrome P-450 Enzyme System; Drug Intera | 2014 |
Case Report: Atrial Fibrillation After Intravenous Administration of Iodinated Contrast Medium in a Patient With Hepatocellular Carcinoma.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzamides; Carcinoma, Hepatocellular | 2015 |
Pilot study of transarterial chemoembolization with pirarubicin and amiodarone for unresectable hepatocellular carcinoma.
Topics: Aged; Aged, 80 and over; Amiodarone; Antineoplastic Agents; Carcinoma, Hepatocellular; Chemoemboliza | 2009 |
Effects of drugs in subtoxic concentrations on the metabolic fluxes in human hepatoma cell line Hep G2.
Topics: Amiodarone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Chromatography, High Pr | 2009 |
Induction of vesicular steatosis by amiodarone and tetracycline is associated with up-regulation of lipogenic genes in HepaRG cells.
Topics: Amiodarone; Carcinoma, Hepatocellular; Carrier Proteins; Cell Line, Tumor; Down-Regulation; Fatty Ac | 2011 |
Acute amiodarone hepatotoxicity after liver transplantation.
Topics: Acute Disease; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Carcinoma, Hepatocellular; C | 2011 |
[Sustained clinical response of large hepatocellular carcinoma after chemoembolization with pirarubicin, amiodarone and Lipiodol].
Topics: alpha-Fetoproteins; Amiodarone; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; Contrast | 2004 |
Expression of cytochromes P450, conjugating enzymes and nuclear receptors in human hepatoma HepaRG cells.
Topics: Acetaminophen; Aflatoxin B1; Amiodarone; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Survival; | 2006 |
Drug competition for intracellular triiodothyronine-binding sites.
Topics: Amiodarone; Animals; Anti-Inflammatory Agents, Non-Steroidal; Binding Sites; Binding, Competitive; C | 1994 |
Effects of triiodothyronine and amiodarone on the promoter of the human LDL receptor gene.
Topics: Amiodarone; Anti-Arrhythmia Agents; Carcinoma, Hepatocellular; Gene Expression; Humans; Liver Neopla | 1998 |
Increased cytotoxicity and stability of Lipiodol-pirarubicin emulsion compared to classical doxorubicin-Lipiodol: potential advantage for chemoembolization of unresectable hepatocellular carcinoma.
Topics: Amiodarone; Antibiotics, Antineoplastic; Carcinoma, Hepatocellular; Chemoembolization, Therapeutic; | 2001 |
[Advanced hepatocellular carcinoma: value of systemic chemotherapy combining adriamycin, amiodarone and 5-fluorouracil].
Topics: Adult; Aged; Amiodarone; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Hepatocellular; | 1989 |