Page last updated: 2024-10-22

amiodarone and Heart Valve Diseases

amiodarone has been researched along with Heart Valve Diseases in 25 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Heart Valve Diseases: Pathological conditions involving any of the various HEART VALVES and the associated structures (PAPILLARY MUSCLES and CHORDAE TENDINEAE).

Research Excerpts

ExcerptRelevanceReference
"The intraoperative use of amiodarone in patients with atrial fibrillation (AF) undergoing valvular heart surgery was unclear."9.14The effect of amiodarone on cardiac rhythm after cardiopulmonary bypass in patients with atrial fibrillation. ( Jie, S; Xiaohu, L; Xiaoyang, T; Yanning, Q; Yu, C; Zhengnian, D, 2010)
"The safety and efficacy of amiodarone and propafenone in converting atrial fibrillation or flutter after cardiac surgery were compared in a randomized double-blind trial."9.08Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation. ( Cappiello, E; Di Biasi, P; Mangini, A; Paje, A; Santoli, C; Scrofani, R, 1995)
"Thirty consecutive patients with chronic rheumatic atrial fibrillation (AF) > or = 3 months after successful mitral valve surgery and left atrial diameter < or = 60 mm were treated with oral amiodarone."7.68Effectiveness of amiodarone and electrical cardioversion for chronic rheumatic atrial fibrillation after mitral valve surgery. ( Essop, MR; Röthlisberger, C; Sareli, P; Skoularigis, J; Skudicky, D; Wisenbaugh, T, 1993)
"The intraoperative use of amiodarone in patients with atrial fibrillation (AF) undergoing valvular heart surgery was unclear."5.14The effect of amiodarone on cardiac rhythm after cardiopulmonary bypass in patients with atrial fibrillation. ( Jie, S; Xiaohu, L; Xiaoyang, T; Yanning, Q; Yu, C; Zhengnian, D, 2010)
"The safety and efficacy of amiodarone and propafenone in converting atrial fibrillation or flutter after cardiac surgery were compared in a randomized double-blind trial."5.08Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation. ( Cappiello, E; Di Biasi, P; Mangini, A; Paje, A; Santoli, C; Scrofani, R, 1995)
"We enrolled 52 patients with atrial fibrillation and valve disease divided in 2 groups: group 1 (26 patients) underwent intraoperative radiofrequency ablation and was followed by a team of skilled cardiologists who treated recurrences with amiodarone and electrical cardioversion; group 2 (26 patients) was treated with intraoperative radiofrequency ablation but patients were thereafter treated by their local hospital or personal cardiologist."3.78Role of an aggressive rhythm control strategy on sinus rhythm maintenance following intra-operative radiofrequency ablation of atrial fibrillation in patients undergoing surgical correction of valvular disease. ( Buja, G; Gerosa, G; Leoni, L; Nalli, C; Sponga, S; Voisine, P, 2012)
"Thirty consecutive patients with chronic rheumatic atrial fibrillation (AF) > or = 3 months after successful mitral valve surgery and left atrial diameter < or = 60 mm were treated with oral amiodarone."3.68Effectiveness of amiodarone and electrical cardioversion for chronic rheumatic atrial fibrillation after mitral valve surgery. ( Essop, MR; Röthlisberger, C; Sareli, P; Skoularigis, J; Skudicky, D; Wisenbaugh, T, 1993)
"Our use of amiodarone in 200 patients during an 8-year period confirms our previous experience which indicated that the drug was close to being the ideal antiarrhythmic agent in children's arrhythmias."3.66The use of amiodarone in children. ( Coumel, P; Do Ngoc, D; Lucet, V, 1983)
"Amiodarone was the most widely used active compound (82%) and apparently the most effective."1.39[Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs]. ( Alegret, JM; Freire, F; Romero-Menor, C; Viñolas, X, 2013)
"Amiodarone is an anti-arrhythmic drug for life-threatening tachycardia, but various adverse effects have been reported."1.35Amiodarone-related pulmonary mass and unique membranous glomerulonephritis in a patient with valvular heart disease: Diagnostic pitfall and new findings. ( Katayama, T; Kimura, T; Kuramochi, S; Okada, Y; Ueda, Y; Yamada, T; Yoshikawa, T, 2008)
"Amiodarone or sotalol was used in all postoperative patients for 6 months, except in 8 who had bradycardia."1.33Ablation of atrial fibrillation using microwave energy--early experience. ( Hamzeh, K; Jamil, H; Kabbani, SS; Murad, G; Sabbagh, A, 2005)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19907 (28.00)18.7374
1990's3 (12.00)18.2507
2000's9 (36.00)29.6817
2010's6 (24.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Yan, S1
Yu, J1
Xia, Z1
Zhu, B1
Hu, J1
Li, J1
Denault, AY1
Beaulieu, Y1
Couture, P1
Haddad, F1
Shi, Y1
Pagé, P1
Levesque, S1
Tardif, JC1
Lambert, J1
Dahl, P1
Danzi, S1
Klein, I1
Kimura, T1
Kuramochi, S1
Katayama, T1
Yoshikawa, T1
Yamada, T1
Ueda, Y1
Okada, Y1
Pires, LM1
Leiria, TL1
de Lima, GG1
Kruse, ML1
Nesralla, IA1
Kalil, RA1
Jie, S1
Yu, C1
Xiaohu, L1
Yanning, Q1
Zhengnian, D1
Xiaoyang, T1
Sponga, S1
Leoni, L1
Buja, G1
Nalli, C1
Voisine, P1
Gerosa, G1
Viñolas, X1
Freire, F1
Romero-Menor, C1
Alegret, JM1
Lee, J1
Lee, B1
Kim, K1
Ahn, H1
Suh, O1
Lee, M1
Shin, W1
Akpinar, B1
Guden, M1
Sagbas, E1
Sanisoglu, I1
Ozbek, U1
Caynak, B1
Bayindir, O1
Scherer, M1
Dzemali, O1
Aybek, T1
Wimmer-Greinecker, G1
Moritz, A1
Kabbani, SS1
Murad, G1
Jamil, H1
Sabbagh, A1
Hamzeh, K1
Shiga, T1
Vora, A1
Coumel, P1
Lucet, V1
Do Ngoc, D1
Sanmartí, A1
Permanyer-Miralda, G1
Castellanos, JM1
Foz-Sala, M1
Galard, RM1
Soler-Soler, J1
Vitolo, E1
Tronci, M1
Larovere, MT1
Rumolo, R1
Skoularigis, J1
Röthlisberger, C1
Skudicky, D1
Essop, MR1
Wisenbaugh, T1
Sareli, P1
Di Biasi, P1
Scrofani, R1
Paje, A1
Cappiello, E1
Mangini, A1
Santoli, C1
Narasimhan, C1
Jazayeri, MR1
Sra, J1
Dhala, A1
Deshpande, S1
Biehl, M1
Akhtar, M1
Blanck, Z1
Grönefeld, GC1
Li, YG1
Bogun, F1
Hohnloser, SH1
Cañas, M1
Rosselot, I1
Bahamonde, L1
Rosselot, E1
Huang, ZD1
Deng, HF1
Zhang, BX1
Brodsky, MA1
Allen, BJ1
Walker, CJ1
Casey, TP1
Luckett, CR1
Henry, WL1
George, M1
Villard, J1
Bastien, O1
Hercule, C1
Lehot, JJ1
Nicolai, Y1
Gensous, D1
Estanove, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Multi-center, Open Label, Randomised Parallel- Group Study to Compare the Efficacy of Cholestyramine Plus Standard Treatment Versus Prednisolone Plus Standard Treatment Versus Standard Treatment Alone in Treatment of Overt Hyperthyroidism[NCT03303053]Phase 3135 participants (Anticipated)Interventional2017-05-11Recruiting
Dual Shock Versus Single Shock Synchronized External Direct Current Cardioversion for Atrial Fibrillation - A Double-blinded Randomized Trial[NCT03943693]Phase 4100 participants (Actual)Interventional2019-04-01Terminated (stopped due to Poor enrollment)
Modeling of Amiodarone Effect on Heart Rate Control in Critically Ill Patients With Atrial Tachyarrhythmias[NCT03413150]80 participants (Actual)Observational2007-01-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for amiodarone and Heart Valve Diseases

ArticleYear
Thyrotoxic cardiac disease.
    Current heart failure reports, 2008, Volume: 5, Issue:3

    Topics: Adrenergic Antagonists; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cardiomyopathy, Di

2008
Approach to management of atrial fibrillation in the Indian scenario.
    The Journal of the Association of Physicians of India, 2007, Volume: 55 Suppl

    Topics: Age Factors; Amiodarone; Angiotensin II Type 1 Receptor Blockers; Anti-Arrhythmia Agents; Anticoagul

2007

Trials

6 trials available for amiodarone and Heart Valve Diseases

ArticleYear
Acute intraoperative effect of intravenous amiodarone on right ventricular function in patients undergoing valvular surgery.
    European heart journal. Acute cardiovascular care, 2015, Volume: 4, Issue:4

    Topics: Administration, Intravenous; Amiodarone; Double-Blind Method; Echocardiography, Doppler; Echocardiog

2015
Comparison of surgical cut and sew versus radiofrequency pulmonary veins isolation for chronic permanent atrial fibrillation: a randomized study.
    Pacing and clinical electrophysiology : PACE, 2010, Volume: 33, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Chronic Disease; F

2010
The effect of amiodarone on cardiac rhythm after cardiopulmonary bypass in patients with atrial fibrillation.
    The Journal of heart valve disease, 2010, Volume: 19, Issue:6

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pacing, Artificial; Cardiopulmonary

2010
Combined radiofrequency modified maze and mitral valve procedure through a port access approach: early and mid-term results.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 2003, Volume: 24, Issue:2

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Echocardiography,

2003
Intravenous amiodarone vs propafenone for atrial fibrillation and flutter after cardiac operation.
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1995, Volume: 9, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flutter; Coronary Disease; Dos

1995
Efficacy and safety of transvenous atrial cardioversion in patients with mitral valve disease and long-standing atrial fibrillation.
    Pacing and clinical electrophysiology : PACE, 2000, Volume: 23, Issue:11 Pt 2

    Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Catheterizati

2000

Other Studies

17 other studies available for amiodarone and Heart Valve Diseases

ArticleYear
A rare form of extremely wide QRS complex due to reversed homologous electrical ventricular separation of acute heart failure.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2018, Volume: 23, Issue:1

    Topics: Acute Disease; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Benzaze

2018
Amiodarone-related pulmonary mass and unique membranous glomerulonephritis in a patient with valvular heart disease: Diagnostic pitfall and new findings.
    Pathology international, 2008, Volume: 58, Issue:10

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cytoplasm; Diagnostic Errors; Fatal Outcome; Foam Cells; G

2008
Role of an aggressive rhythm control strategy on sinus rhythm maintenance following intra-operative radiofrequency ablation of atrial fibrillation in patients undergoing surgical correction of valvular disease.
    Journal of cardiology, 2012, Volume: 60, Issue:4

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Electric Countershock; F

2012
[Predictors of reversion to sinus rhythm previous to electrical cardioversion in patients with persistent atrial fibrillation treated with anti-arrhythmic drugs].
    Medicina clinica, 2013, Apr-20, Volume: 140, Issue:8

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Body Mass Index; Comorbidity; Diabete

2013
Factors affecting warfarin therapy following cardiac valve surgery.
    The Annals of pharmacotherapy, 2002, Volume: 36, Issue:12

    Topics: Adult; Amiodarone; Anticoagulants; Dose-Response Relationship, Drug; Drug Interactions; Ethnicity; F

2002
Impact of left atrial size reduction on chronic atrial fibrillation in mitral valve surgery.
    The Journal of heart valve disease, 2003, Volume: 12, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiac Pac

2003
Ablation of atrial fibrillation using microwave energy--early experience.
    Asian cardiovascular & thoracic annals, 2005, Volume: 13, Issue:3

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Coronary Ar

2005
Atrial fibrillation and rheumatic valvular heart disease: usefulness of very-low-dose amiodarone.
    Chinese medical journal, 2006, Dec-20, Volume: 119, Issue:24

    Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Heart Valve Diseases; Humans; Quality of Li

2006
The use of amiodarone in children.
    Pacing and clinical electrophysiology : PACE, 1983, Volume: 6, Issue:5 Pt 1

    Topics: Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Benzofurans; Bundle-Branch Bl

1983
Chronic administration of amiodarone and thyroid function: a follow-up study.
    American heart journal, 1984, Volume: 108, Issue:5

    Topics: Adult; Aged; Amiodarone; Benzofurans; Chronic Disease; Coronary Disease; Female; Follow-Up Studies;

1984
[Comparison of the effectiveness of amiodarone and quinidine in the prevention of arrhythmia].
    Bollettino della Societa italiana di cardiologia, 1980, Volume: 25, Issue:9

    Topics: Adult; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Benzofurans; Cardiomyopathies; Female;

1980
Effectiveness of amiodarone and electrical cardioversion for chronic rheumatic atrial fibrillation after mitral valve surgery.
    The American journal of cardiology, 1993, Aug-15, Volume: 72, Issue:5

    Topics: Adult; Amiodarone; Atrial Fibrillation; Chronic Disease; Combined Modality Therapy; Electric Counter

1993
Ventricular tachycardia in valvular heart disease: facilitation of sustained bundle-branch reentry by valve surgery.
    Circulation, 1997, Dec-16, Volume: 96, Issue:12

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Bundle of His; Defibrillators, Implantable; Electro

1997
[Electric cardioversion in the postoperative period after mitral valve surgery].
    Revista medica de Chile, 1986, Volume: 114, Issue:7

    Topics: Adolescent; Adult; Amiodarone; Atrial Fibrillation; Electric Countershock; Female; Heart Valve Disea

1986
[Postoperative therapeutic effect of amiodarone on the conversion of chronic atrial fibrillation in rheumatic heart disease].
    Zhonghua nei ke za zhi, 1987, Volume: 26, Issue:2

    Topics: Adult; Amiodarone; Atrial Fibrillation; Chronic Disease; Female; Heart Valve Diseases; Heart Valve P

1987
Amiodarone for maintenance of sinus rhythm after conversion of atrial fibrillation in the setting of a dilated left atrium.
    The American journal of cardiology, 1987, Sep-01, Volume: 60, Issue:7

    Topics: Adult; Aged; Amiodarone; Atrial Fibrillation; Cardiomyopathy, Dilated; Female; Heart Atria; Heart Va

1987
[3-week saturation with amiodarone before heart valve surgery. Study of postoperative rhythm disorders and plasma and myocardial levels of amiodarone].
    Cahiers d'anesthesiologie, 1987, Volume: 35, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Arrhythmias, Cardiac; Drug Administration Schedule; Elec

1987