Page last updated: 2024-10-22

amiodarone and Goiter, Nodular

amiodarone has been researched along with Goiter, Nodular in 11 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Goiter, Nodular: An enlarged THYROID GLAND containing multiple nodules (THYROID NODULE), usually resulting from recurrent thyroid HYPERPLASIA and involution over many years to produce the irregular enlargement. Multinodular goiters may be nontoxic or may induce THYROTOXICOSIS.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone-induced thyrotoxicosis (AIT) develops in 3% of amiodarone-treated patients in North America."8.85Amiodarone-induced thyrotoxicosis: a review. ( Houlden, RL; Tsang, W, 2009)
"To report a case of amiodarone-induced thyrotoxicosis (AIT) concomitant with thyroid cancer in multinodular goiter (MNG)."7.78Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case report. ( Akamizu, T; Inaba, H; Kobayashi, S; Komatsu, M; Suzuki, S; Takeda, T, 2012)
"A 64-year-old female with atrial fibrillation and nodular goiter progressed to overt thyrotoxicosis after receiving therapy with amiodarone 200 mg/day for less than 12 weeks."7.75Amiodarone-induced thyrotoxicosis in a patient with autonomously functioning nodular goiter. ( Hsiao, SH; Huang, SM; Hung, HC; Liang, YL; Ou, HY; Peng, SL; Wu, TJ, 2009)
"Amiodarone-induced thyrotoxicosis is a life-threatening condition."7.74Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
"Amiodarone-induced thyrotoxicosis (AIT) may be caused by excessive thyroidal hormone synthesis and release (type 1) or by a destructive process (type 2)."7.74Color-flow Doppler sonography in the differential diagnosis and management of amiodarone-induced thyrotoxicosis. ( Cianchetti, ME; Loy, M; Mariotti, S; Melis, A; Perra, E; Piga, M; Pinna, G; Serra, A, 2007)
"Amiodarone-induced thyrotoxicosis (AIT) is a challenging management problem, since patients treated with amiodarone invariably have underlying heart disease."7.73Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality. ( Diamond, T; Lewis, M; O'Sullivan, AJ, 2006)
"Amiodarone-induced thyrotoxicosis (AIT) occurs both in abnormal thyroid glands (nodular goiter, latent Graves' disease) (type I AIT) or in apparently normal thyroid glands (type II AIT)."7.69Color flow Doppler sonography rapidly differentiates type I and type II amiodarone-induced thyrotoxicosis. ( Bartalena, L; Bartolozzi, C; Bogazzi, F; Brogioni, S; Burelli, A; Martino, E; Mazzeo, S; Vitti, P, 1997)
"Iodine-induced hyperthyroidism has been frequently described when iodine is introduced into an iodine-deficient area."7.67Five patients with iodine-induced hyperthyroidism. ( Braverman, LE; Mordes, JP; Rajatanavin, R; Safran, M; Stoller, WA, 1984)
"The off-label use of OCAs was reviewed for the management of neonatal and adult Graves' disease, subacute thyroiditis, amiodarone-induced thyroiditis (AIT), exogenous hyperthyroidism, toxic multinodular goiter (TMNG), thyrotropinoma, thyrotoxicosis during pregnancy, rapid pre-operative control of hyperthyroidism, and thyroid storm."4.90Review of oral cholecystographic agents for the management of hyperthyroidism. ( Kim, TY; Martinez, DS; Tyer, NM, 2014)
"Amiodarone-induced thyrotoxicosis (AIT) develops in 3% of amiodarone-treated patients in North America."4.85Amiodarone-induced thyrotoxicosis: a review. ( Houlden, RL; Tsang, W, 2009)
"To report a case of amiodarone-induced thyrotoxicosis (AIT) concomitant with thyroid cancer in multinodular goiter (MNG)."3.78Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case report. ( Akamizu, T; Inaba, H; Kobayashi, S; Komatsu, M; Suzuki, S; Takeda, T, 2012)
"A 64-year-old female with atrial fibrillation and nodular goiter progressed to overt thyrotoxicosis after receiving therapy with amiodarone 200 mg/day for less than 12 weeks."3.75Amiodarone-induced thyrotoxicosis in a patient with autonomously functioning nodular goiter. ( Hsiao, SH; Huang, SM; Hung, HC; Liang, YL; Ou, HY; Peng, SL; Wu, TJ, 2009)
"Amiodarone-induced thyrotoxicosis is a life-threatening condition."3.74Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study. ( Ambrosini, CE; Berti, P; Bogazzi, F; Martino, E; Materazzi, G; Miccoli, P, 2007)
"Amiodarone-induced thyrotoxicosis (AIT) may be caused by excessive thyroidal hormone synthesis and release (type 1) or by a destructive process (type 2)."3.74Color-flow Doppler sonography in the differential diagnosis and management of amiodarone-induced thyrotoxicosis. ( Cianchetti, ME; Loy, M; Mariotti, S; Melis, A; Perra, E; Piga, M; Pinna, G; Serra, A, 2007)
"Amiodarone-induced thyrotoxicosis (AIT) is a challenging management problem, since patients treated with amiodarone invariably have underlying heart disease."3.73Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality. ( Diamond, T; Lewis, M; O'Sullivan, AJ, 2006)
"Amiodarone-induced thyrotoxicosis (AIT) occurs both in abnormal thyroid glands (nodular goiter, latent Graves' disease) (type I AIT) or in apparently normal thyroid glands (type II AIT)."3.69Color flow Doppler sonography rapidly differentiates type I and type II amiodarone-induced thyrotoxicosis. ( Bartalena, L; Bartolozzi, C; Bogazzi, F; Brogioni, S; Burelli, A; Martino, E; Mazzeo, S; Vitti, P, 1997)
"Iodine-induced hyperthyroidism has been frequently described when iodine is introduced into an iodine-deficient area."3.67Five patients with iodine-induced hyperthyroidism. ( Braverman, LE; Mordes, JP; Rajatanavin, R; Safran, M; Stoller, WA, 1984)
"Thyrotoxicosis is a common disorder, especially in women."2.48Thyrotoxicosis. ( Boelaert, K; Franklyn, JA, 2012)
"Thyrotoxicosis is a well defined clinical entity, determined by an increase of plasma levels of thyroid hormones (T3 and T4)."2.41[The management of thyrotoxicosis: a schematic approach]. ( Carapezzi, C; Corsello, SM; Papi, G, 2002)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19901 (9.09)18.7374
1990's1 (9.09)18.2507
2000's6 (54.55)29.6817
2010's3 (27.27)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tyer, NM1
Kim, TY1
Martinez, DS1
Liang, YL1
Huang, SM1
Peng, SL1
Hsiao, SH1
Hung, HC1
Ou, HY1
Wu, TJ1
Tsang, W1
Houlden, RL1
Inaba, H1
Suzuki, S1
Takeda, T1
Kobayashi, S1
Akamizu, T1
Komatsu, M1
Franklyn, JA1
Boelaert, K1
O'Sullivan, AJ1
Lewis, M1
Diamond, T1
Berti, P1
Materazzi, G1
Bogazzi, F2
Ambrosini, CE1
Martino, E2
Miccoli, P1
Loy, M1
Perra, E1
Melis, A1
Cianchetti, ME1
Piga, M1
Serra, A1
Pinna, G1
Mariotti, S1
Rajatanavin, R1
Safran, M1
Stoller, WA1
Mordes, JP1
Braverman, LE1
Bartalena, L1
Brogioni, S1
Mazzeo, S1
Vitti, P1
Burelli, A1
Bartolozzi, C1
Papi, G1
Carapezzi, C1
Corsello, SM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Randomized, Open-label, Parallel-group Study to Explore the Efficacy of High-intensity Focused Ultrasound (HIFU) Versus Fixed-dose Radioiodine-131 in the Treatment of Relapsed Graves' Disease[NCT03013257]240 participants (Actual)Interventional2017-04-25Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for amiodarone and Goiter, Nodular

ArticleYear
Review of oral cholecystographic agents for the management of hyperthyroidism.
    Endocrine practice : official journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists, 2014, Volume: 20, Issue:10

    Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Female; Goiter, Nodular; Humans; Hyperthyroidism; Neoplas

2014
Amiodarone-induced thyrotoxicosis: a review.
    The Canadian journal of cardiology, 2009, Volume: 25, Issue:7

    Topics: Amiodarone; Anti-Arrhythmia Agents; Goiter, Nodular; Graves Disease; Humans; Thyroiditis, Subacute;

2009
Thyrotoxicosis.
    Lancet (London, England), 2012, Mar-24, Volume: 379, Issue:9821

    Topics: Agranulocytosis; Amiodarone; Antithyroid Agents; Atrial Fibrillation; Autoimmune Diseases; Child; Ex

2012
[The management of thyrotoxicosis: a schematic approach].
    Minerva endocrinologica, 2002, Volume: 27, Issue:2

    Topics: Adenoma; Adrenal Cortex Hormones; Adult; Aged; Amiodarone; Antithyroid Agents; Cardiovascular Diseas

2002

Other Studies

7 other studies available for amiodarone and Goiter, Nodular

ArticleYear
Amiodarone-induced thyrotoxicosis in a patient with autonomously functioning nodular goiter.
    The Annals of pharmacotherapy, 2009, Volume: 43, Issue:1

    Topics: Amiodarone; Anti-Arrhythmia Agents; Female; Goiter, Nodular; Humans; Middle Aged; Thyrotoxicosis

2009
Amiodarone-induced thyrotoxicosis with thyroid papillary cancer in multinodular goiter: case report.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2012, Volume: 21, Issue:2

    Topics: Amiodarone; Anti-Arrhythmia Agents; Carcinoma; Carcinoma, Papillary; Goiter, Nodular; Humans; Male;

2012
Amiodarone-induced thyrotoxicosis: left ventricular dysfunction is associated with increased mortality.
    European journal of endocrinology, 2006, Volume: 154, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Female; Goiter, Nodular; Graves Disease; Humans; Male

2006
Combination of minimally invasive thyroid surgery and local anesthesia associated to iopanoic acid for patients with amiodarone-induced thyrotoxicosis and severe cardiac disorders: a pilot study.
    Langenbeck's archives of surgery, 2007, Volume: 392, Issue:6

    Topics: Aged; Amiodarone; Anesthesia, Local; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Autonomic Nerve B

2007
Color-flow Doppler sonography in the differential diagnosis and management of amiodarone-induced thyrotoxicosis.
    Acta radiologica (Stockholm, Sweden : 1987), 2007, Volume: 48, Issue:6

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Goiter, Nodular; Graves D

2007
Five patients with iodine-induced hyperthyroidism.
    The American journal of medicine, 1984, Volume: 77, Issue:2

    Topics: Adult; Amiodarone; Chlorobutanol; Coloring Agents; Coronary Artery Bypass; Drug Combinations; Female

1984
Color flow Doppler sonography rapidly differentiates type I and type II amiodarone-induced thyrotoxicosis.
    Thyroid : official journal of the American Thyroid Association, 1997, Volume: 7, Issue:4

    Topics: Adult; Aged; Amiodarone; Antithyroid Agents; Diagnosis, Differential; Female; Glucocorticoids; Goite

1997