Page last updated: 2024-10-22

amiodarone and Genetic Predisposition

amiodarone has been researched along with Genetic Predisposition in 6 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Research Excerpts

ExcerptRelevanceReference
"The aim of this study was to evaluate the survival of patients with hypertrophic cardiomyopathy (HCM) after resuscitated ventricular fibrillation or syncopal sustained ventricular tachycardia (VT/VF) when treated with low dose amiodarone or implantable cardioverter defibrillators (ICDs)."3.70Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy. ( Elliott, PM; McKenna, WJ; Poloniecki, J; Rowland, E; Sharma, S; Varnava, A, 1999)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Adachi, Y1
Hayashi, T1
Mitsuhashi, T1
Sakakura, K1
Yamada, Y1
Wada, Y1
Horie, M1
Momomura, SI1
Fujita, H1
Montes, R1
Nantes, O1
Alonso, A1
Zozaya, JM1
Hermida, J1
Kozák, M1
Izákovicová Hollá, L1
Krivan, L1
Vasků, A1
Sepsi, M1
Semrád, B1
Vácha, J1
Lehtonen, A1
Fodstad, H1
Laitinen-Forsblom, P1
Toivonen, L1
Kontula, K1
Swan, H1
Wilson, BD1
Lippmann, ML1
Elliott, PM1
Sharma, S1
Varnava, A1
Poloniecki, J1
Rowland, E1
McKenna, WJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
EvaLuation Using Cardiac Insertable Devices And TelephonE in Hypertrophic CardioMyopathy[NCT03259113]30 participants (Anticipated)Interventional2017-08-16Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

6 other studies available for amiodarone and Genetic Predisposition

ArticleYear
Late presentation of arrhythmogenic right ventricular cardiomyopathy in an octogenarian associated with a pathogenic variant in the plakophilin 2 gene: a case report.
    BMC cardiovascular disorders, 2019, 02-19, Volume: 19, Issue:1

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Arrhythmogenic Right Ventricular Dysplasia; C

2019
The influence of polymorphisms of VKORC1 and CYP2C9 on major gastrointestinal bleeding risk in anticoagulated patients.
    British journal of haematology, 2008, Volume: 143, Issue:5

    Topics: Acenocoumarol; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents

2008
Endothelin-1 gene polymorphism in patients with malignant arrhythmias.
    Journal of cardiovascular pharmacology, 2004, Volume: 44 Suppl 1

    Topics: Aged; Amino Acid Sequence; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Defibrillators,

2004
Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.
    Heart rhythm, 2007, Volume: 4, Issue:5

    Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; DNA Mutational Analysis; Electrocardiog

2007
Susceptibility to amiodarone-induced pulmonary toxicity: relationship to the uptake of amiodarone by isolated lung cells.
    Lung, 1996, Volume: 174, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cells, Cultured; Fibroblasts; Genetic Predisposition to

1996
Survival after cardiac arrest or sustained ventricular tachycardia in patients with hypertrophic cardiomyopathy.
    Journal of the American College of Cardiology, 1999, Volume: 33, Issue:6

    Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Hypertrophic; Child; Death, S

1999