amiodarone has been researched along with Gastrointestinal Hemorrhage in 7 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Gastrointestinal Hemorrhage: Bleeding in any segment of the GASTROINTESTINAL TRACT from ESOPHAGUS to RECTUM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An 88-year-old female, living independently in the community, developed duodenal and gastric ulcers from using overthe-counter naproxen sodium for pain related to a shoulder fracture and arthritis of the knees." | 4.88 | Gastrointestinal bleeding and possible hypothyroidism. ( Marshall, LL, 2012) |
| "Amiodarone is a lipophilic drug that concentrates in the liver and usually, over a period of time, leads to toxicity related to drug accumulation." | 1.35 | Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use. ( Chang, C; Fiel, MI; Raja, K; Thung, SN, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Grymonprez, M | 1 |
| Vanspranghe, K | 1 |
| Steurbaut, S | 1 |
| De Backer, TL | 1 |
| Lahousse, L | 1 |
| Lin, SY | 1 |
| Liu, YB | 1 |
| Ho, LT | 1 |
| Peng, YF | 1 |
| Kuo, CH | 1 |
| Tang, SC | 1 |
| Huang, CF | 1 |
| Jeng, JS | 1 |
| Montes, R | 1 |
| Nantes, O | 1 |
| Alonso, A | 1 |
| Zozaya, JM | 1 |
| Hermida, J | 1 |
| Raja, K | 1 |
| Thung, SN | 1 |
| Fiel, MI | 1 |
| Chang, C | 1 |
| Werner, CR | 1 |
| Riessen, R | 1 |
| Gregor, M | 1 |
| Bitzer, M | 1 |
| Marshall, LL | 1 |
| Farooq, V | 1 |
| Serruys, PW | 1 |
| Bourantas, C | 1 |
| Vranckx, P | 1 |
| Diletti, R | 1 |
| Garcia Garcia, HM | 1 |
| Holmes, DR | 1 |
| Kappetein, AP | 1 |
| Mack, M | 1 |
| Feldman, T | 1 |
| Morice, MC | 1 |
| Colombo, A | 1 |
| Morel, MA | 1 |
| de Vries, T | 1 |
| van Es, GA | 1 |
| Steyerberg, EW | 1 |
| Dawkins, KD | 1 |
| Mohr, FW | 1 |
| James, S | 1 |
| Ståhle, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Synergy Between PCI With TAXUS and Cardiac Surgery: SYNTAX Extended Survival[NCT03417050] | 2,636 participants (Actual) | Observational | 2016-12-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for amiodarone and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Non-vitamin K Antagonist Oral Anticoagulants (NOACs) Versus Warfarin in Patients with Atrial Fibrillation Using P-gp and/or CYP450-Interacting Drugs: a Systematic Review and Meta-analysis.
Topics: Administration, Oral; Amiodarone; Anticoagulants; ATP Binding Cassette Transporter, Subfamily B, Mem | 2023 |
Gastrointestinal bleeding and possible hypothyroidism.
Topics: Aged, 80 and over; Amiodarone; Anemia; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroid | 2012 |
1 trial available for amiodarone and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Incidence and multivariable correlates of long-term mortality in patients treated with surgical or percutaneous revascularization in the synergy between percutaneous coronary intervention with taxus and cardiac surgery (SYNTAX) trial.
Topics: Aged; Amiodarone; Coronary Artery Bypass; Coronary Artery Disease; Female; Gastrointestinal Hemorrha | 2012 |
4 other studies available for amiodarone and Gastrointestinal Hemorrhage
| Article | Year |
|---|---|
Impact of amiodarone on plasma concentration of direct oral anticoagulant in patients with atrial fibrillation.
Topics: Administration, Oral; Amiodarone; Anticoagulants; Atrial Fibrillation; Gastrointestinal Hemorrhage; | 2023 |
The influence of polymorphisms of VKORC1 and CYP2C9 on major gastrointestinal bleeding risk in anticoagulated patients.
Topics: Acenocoumarol; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents | 2008 |
Drug-induced steatohepatitis leading to cirrhosis: long-term toxicity of amiodarone use.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Biopsy; Chemical and Drug Induced Liver Injury; Diagnosis, | 2009 |
[Unexpected complication following esophageal variceal hemorrhage - Case 2/2011].
Topics: Amiodarone; Anti-Bacterial Agents; Ciprofloxacin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inh | 2011 |