amiodarone has been researched along with Fabry Disease in 10 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Fabry Disease: An X-linked inherited metabolic disease caused by a deficiency of lysosomal ALPHA-GALACTOSIDASE A. It is characterized by intralysosomal accumulation of globotriaosylceramide and other GLYCOSPHINGOLIPIDS in blood vessels throughout the body leading to multi-system complications including renal, cardiac, cerebrovascular, and skin disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 54-year-old man with the lysosomal storage disorder Anderson-Fabry disease (AFD) and cardiac involvement was placed on amiodarone for treatment of symptomatic paroxysmal atrial fibrillation." | 7.91 | Acute Decompensated Heart Failure After Initiation of Amiodarone in a Patient With Anderson-Fabry Disease. ( Fine, NM; Khan, A; Wang, Y, 2019) |
| "The aim of this work is to compare the microstructure of cornea verticillata in Fabry disease with amiodarone-induced keratopathy by means of in vivo confocal laser-scanning microscopy (CLSM)." | 7.77 | Confocal laser-scanning microscopy allows differentiation between Fabry disease and amiodarone-induced keratopathy. ( Pfeiffer, N; Pitz, S; Reinke, J; Wasielica-Poslednik, J, 2011) |
| "The purpose of this study is to describe cornea verticillata in Fabry disease and in amiodarone-induced keratopathy and to compare the corneal microstructure of both types." | 7.75 | The microstructure of cornea verticillata in Fabry disease and amiodarone-induced keratopathy: a confocal laser-scanning microscopy study. ( Büttner, A; Falke, K; Guthoff, R; Kraak, R; Rolfs, A; Schittkowski, M; Stachs, O; Zhivov, A, 2009) |
| "Therapy with cationic amphiphilic drugs (Amiodarone or hydroxychloroquine) may result in biochemically and ultrastructurally similar lipid inclusions in many cells also affected by Fabry disease (FD)." | 4.02 | Incidental finding of cornea verticillata or lamellar inclusions in kidney biopsy: measurement of lyso-Gb3 in plasma defines between Fabry disease and drug-induced phospholipidosis. ( Albertón, V; Barriales-Villa, R; Di Pietrantonio, S; Durand, C; Fernandez, A; Frabasil, J; Larrañaga-Moreira, J; Politei, J; Schenone, AB; Velasquez Rivas, D, 2021) |
| "A 54-year-old man with the lysosomal storage disorder Anderson-Fabry disease (AFD) and cardiac involvement was placed on amiodarone for treatment of symptomatic paroxysmal atrial fibrillation." | 3.91 | Acute Decompensated Heart Failure After Initiation of Amiodarone in a Patient With Anderson-Fabry Disease. ( Fine, NM; Khan, A; Wang, Y, 2019) |
| "The aim of this work is to compare the microstructure of cornea verticillata in Fabry disease with amiodarone-induced keratopathy by means of in vivo confocal laser-scanning microscopy (CLSM)." | 3.77 | Confocal laser-scanning microscopy allows differentiation between Fabry disease and amiodarone-induced keratopathy. ( Pfeiffer, N; Pitz, S; Reinke, J; Wasielica-Poslednik, J, 2011) |
| "The purpose of this study is to describe cornea verticillata in Fabry disease and in amiodarone-induced keratopathy and to compare the corneal microstructure of both types." | 3.75 | The microstructure of cornea verticillata in Fabry disease and amiodarone-induced keratopathy: a confocal laser-scanning microscopy study. ( Büttner, A; Falke, K; Guthoff, R; Kraak, R; Rolfs, A; Schittkowski, M; Stachs, O; Zhivov, A, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (30.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 4 (40.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Politei, J | 1 |
| Frabasil, J | 1 |
| Durand, C | 1 |
| Di Pietrantonio, S | 1 |
| Fernandez, A | 1 |
| Albertón, V | 1 |
| Velasquez Rivas, D | 1 |
| Barriales-Villa, R | 1 |
| Larrañaga-Moreira, J | 1 |
| Schenone, AB | 1 |
| Fine, NM | 1 |
| Wang, Y | 1 |
| Khan, A | 1 |
| Rao, DA | 1 |
| Lakdawala, NK | 1 |
| Miller, AL | 1 |
| Loscalzo, J | 1 |
| Alp, A | 1 |
| Akdam, H | 1 |
| Falke, K | 1 |
| Büttner, A | 1 |
| Schittkowski, M | 1 |
| Stachs, O | 1 |
| Kraak, R | 1 |
| Zhivov, A | 1 |
| Rolfs, A | 1 |
| Guthoff, R | 1 |
| Wasielica-Poslednik, J | 1 |
| Pfeiffer, N | 1 |
| Reinke, J | 1 |
| Pitz, S | 1 |
| Pintavorn, P | 1 |
| D'Amico, DJ | 1 |
| Kenyon, KR | 1 |
| Zadnik, K | 1 |
| Garmizo, G | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Multiple Sclerosis and Fabry Disease: Prevalence of Fabry Disease in a Defined Population at Risk - Patients Formerly Diagnosed With Multiple Sclerosis - an Epidemiological Study[NCT01271699] | 250 participants (Actual) | Observational | 2011-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 other studies available for amiodarone and Fabry Disease
| Article | Year |
|---|---|
Incidental finding of cornea verticillata or lamellar inclusions in kidney biopsy: measurement of lyso-Gb3 in plasma defines between Fabry disease and drug-induced phospholipidosis.
Topics: Adult; Aged; Amiodarone; Fabry Disease; Glycolipids; Humans; Hydroxychloroquine; Incidental Findings | 2021 |
Acute Decompensated Heart Failure After Initiation of Amiodarone in a Patient With Anderson-Fabry Disease.
Topics: Acute Disease; Administration, Oral; Amiodarone; Biopsy; Cytochrome P-450 CYP1A2 Inhibitors; Echocar | 2019 |
Clinical problem-solving. In the thick of it.
Topics: alpha-Galactosidase; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cardiomegaly; Codon, N | 2013 |
Vortex Keratopathy: Fabry Related or Amiodarone Induced?
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cornea; Corneal Diseases; Diagnosis, Differ | 2015 |
The microstructure of cornea verticillata in Fabry disease and amiodarone-induced keratopathy: a confocal laser-scanning microscopy study.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Conjunctiva; Cornea; Corneal Dis | 2009 |
Confocal laser-scanning microscopy allows differentiation between Fabry disease and amiodarone-induced keratopathy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; alpha-Galactosidase; Amiodarone; Anti-Arrhythmia Agents; | 2011 |
A wild zebra chase.
Topics: Amiodarone; Animals; Diagnosis, Differential; Fabry Disease; Female; Humans; Iatrogenic Disease; Kid | 2008 |
Drug-induced lipidoses of the cornea and conjunctiva.
Topics: Amiodarone; Amodiaquine; Chloroquine; Conjunctival Diseases; Corneal Diseases; Fabry Disease; Female | 1981 |
Fabry's disease.
Topics: Amiodarone; Corneal Diseases; Diagnosis, Differential; Fabry Disease; Humans | 1987 |
Ocular manifestations of Fabry's disease.
Topics: Amiodarone; Corneal Dystrophies, Hereditary; Diagnosis, Differential; Fabry Disease; Humans | 1987 |