Page last updated: 2024-10-22

amiodarone and Eye Diseases

amiodarone has been researched along with Eye Diseases in 25 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Eye Diseases: Diseases affecting the eye.

Research Excerpts

ExcerptRelevanceReference
"Thyroid disorders and eye diseases are interrelated through several mechanisms thus, awareness of this relation has a great impact on early diagnosis and treatment."5.05Thyroid and Eye: Where They Meet in Clinical Practice. ( El-Eshmawy, MM; Shahin, M, 2020)
" In particular, we reviewed the effects of cyanosis, coarctation of the aorta, endocarditis, and the side effects of Sildenafil and Amiodarone."4.98The eye in CHD. ( Celermajer, D; Cordina, R; Liew, G; McCluskey, P; Nasir-Ahmad, S, 2018)
"Amiodarone, an anti-ischaemic and anti-arrhythmic drug, has been the object of numerous studies and seems to be highly effective in the treatment of severe ventricular arrhythmias on dilated cardiomyopathies, as well as of hypertrophic or ischaemic heart diseases."4.78[Does amiodarone have a benefit effect on mortality?]. ( Kahn, JC; Pathé, M, 1991)
"Numerous systemic drugs produce adverse effects that involve the eye."2.38Ocular side effects of selected systemic drugs. ( Jaanus, SD, 1992)
"Amiodarone has a reduced clearance rate, large volume of distribution, low bioavailability and a long half-life that may last 2 months in patients receiving short-term therapy."2.37Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects. ( Heger, JJ; Prystowsky, EN; Zipes, DP, 1984)
" Many of these adverse side effects can be greatly reduced or prevented with close monitoring of patients."1.31Ocular toxicity of systemic medications: a case series. ( To, TQ; Townsend, JC, 2000)
" It is suggested that patients taking amiodarone in high dosage for long periods have their eyes and retinal function monitored."1.27Amiodarone-induced ultrastructural changes in human eyes. ( Ghosh, M; McCulloch, C, 1984)
"Control of arrhythmias was satisfactory in all 12 evaluable patients, when the serum amiodarone level exceeded 1."1.27Serum concentrations of amiodarone during long term therapy. Relation to dose, efficacy and toxicity. ( Bircher, J; Galeazzi, RL; Remund, H; Stäubli, M; Studer, H, 1983)
"An unusual case of recurrence of amiodarone pulmonary toxicity is described."1.27[Recurrent alveolitis caused by amiodarone]. ( Ciani, F; Padrini, R; Pandullo, C; Pivotti, F; Scardi, S, 1986)

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-199015 (60.00)18.7374
1990's5 (20.00)18.2507
2000's2 (8.00)29.6817
2010's2 (8.00)24.3611
2020's1 (4.00)2.80

Authors

AuthorsStudies
Nasir-Ahmad, S1
Cordina, R1
Liew, G1
McCluskey, P1
Celermajer, D1
El-Eshmawy, MM1
Shahin, M1
van Erven, L1
Schalij, MJ1
Imaizumi, M1
Ikebe, T1
Ikewaki, J1
Nakatsuka, K1
Lubbe, WF1
Mercer, CJ1
Friocourt, P1
Coumel, P1
Zipes, DP1
Prystowsky, EN1
Heger, JJ1
Ingram, DV1
Ghosh, M1
McCulloch, C1
Yin, SY1
Perry, HD1
Stäubli, M1
Bircher, J1
Galeazzi, RL1
Remund, H1
Studer, H1
Clemett, RS1
MacKintosh, HT1
Banerjee, S1
James, CB1
Incalzi, RA1
Gemma, A1
Carbonin, PU1
Riihelä, K1
Mäntyjärvi, M1
To, TQ1
Townsend, JC1
Canta, LR1
Jaanus, SD1
Pathé, M1
Kahn, JC1
Taylor, F1
Costa, C1
Visalli, N1
Natoli, A1
Fossati, C1
Disertori, M1
Inama, G1
Scardi, S1
Ciani, F1
Pandullo, C1
Padrini, R1
Pivotti, F1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
aMsa and amiOdarone Study in cArdiaC Arrest[NCT04997980]500 participants (Anticipated)Observational2015-01-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

9 reviews available for amiodarone and Eye Diseases

ArticleYear
The eye in CHD.
    Cardiology in the young, 2018, Volume: 28, Issue:8

    Topics: Adult; Amiodarone; Aortic Coarctation; Cyanosis; Endocarditis; Eye Diseases; Heart Defects, Congenit

2018
Thyroid and Eye: Where They Meet in Clinical Practice.
    Endocrine, metabolic & immune disorders drug targets, 2020, Volume: 20, Issue:1

    Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Antithyroid Agents; Diabetic Retinopathy; Eye; Eye Dise

2020
[Drug-induced visual disturbance].
    Nihon rinsho. Japanese journal of clinical medicine, 2007, Oct-28, Volume: 65 Suppl 8

    Topics: Amiodarone; Anti-Asthmatic Agents; Antimalarials; Antitubercular Agents; Antiviral Agents; Chloroqui

2007
[Side effects of amiodarone].
    Annales de medecine interne, 1983, Volume: 134, Issue:1

    Topics: Amiodarone; Benzofurans; Brain Diseases; Cardiovascular Diseases; Eye Diseases; Humans; Skin Disease

1983
Amiodarone: electrophysiologic actions, pharmacokinetics and clinical effects.
    Journal of the American College of Cardiology, 1984, Volume: 3, Issue:4

    Topics: Administration, Oral; Amiodarone; Animals; Arrhythmias, Cardiac; Atrioventricular Node; Benzofurans;

1984
[Ocular findings associated to the use of amiodarone].
    Duodecim; laaketieteellinen aikakauskirja, 1996, Volume: 112, Issue:9

    Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Cornea; Eye Diseases; Female;

1996
Ocular side effects of selected systemic drugs.
    Optometry clinics : the official publication of the Prentice Society, 1992, Volume: 2, Issue:4

    Topics: Amiodarone; Anti-Inflammatory Agents; Antirheumatic Agents; Chloroquine; Chlorpromazine; Drug Intera

1992
[Does amiodarone have a benefit effect on mortality?].
    Presse medicale (Paris, France : 1983), 1991, Sep-14, Volume: 20, Issue:28

    Topics: Amiodarone; Arrhythmias, Cardiac; Death, Sudden, Cardiac; Eye Diseases; France; Heart Arrest; Humans

1991
[Collateral effects of an anti-arrhythmic agent: amiodarone].
    La Clinica terapeutica, 1985, Sep-30, Volume: 114, Issue:6

    Topics: Amiodarone; Benzofurans; Chemical and Drug Induced Liver Injury; Eye Diseases; Humans; Hyperthyroidi

1985

Trials

1 trial available for amiodarone and Eye Diseases

ArticleYear
[Extracardiac side effects of Aminodarone].
    Giornale italiano di cardiologia, 1986, Volume: 16, Issue:2

    Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Clinical Trials as Topic; Drug Evaluation; Eye Diseas

1986

Other Studies

15 other studies available for amiodarone and Eye Diseases

ArticleYear
Amiodarone: an effective antiarrhythmic drug with unusual side effects.
    Heart (British Cardiac Society), 2010, Volume: 96, Issue:19

    Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Drug Administration Schedule; Drug Eruptio

2010
Amiodarone: its side effects, adverse reactions and dosage schedules.
    The New Zealand medical journal, 1982, Jul-28, Volume: 95, Issue:712

    Topics: Amiodarone; Benzofurans; Central Nervous System Diseases; Drug Administration Schedule; Eye Diseases

1982
Ocular effects in long-term amiodarone therapy.
    American heart journal, 1983, Volume: 106, Issue:4 Pt 2

    Topics: Amiodarone; Benzofurans; Corneal Diseases; Eye Diseases; Humans; Vision Disorders

1983
Amiodarone-induced ultrastructural changes in human eyes.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1984, Volume: 19, Issue:4

    Topics: Amiodarone; Benzofurans; Corneal Diseases; Eye; Eye Diseases; Female; Humans; Male; Retinal Diseases

1984
[Clinical observation on ocular complications after administration of amiodarone in control of arrhythmias].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1982, Volume: 18, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Eye Diseases; Female; Humans; Iodides; M

1982
Drugs and toxins.
    International ophthalmology clinics, 1983,Spring, Volume: 23, Issue:1

    Topics: Adult; Amiodarone; Child; Conjunctivitis; Corneal Diseases; Eye Diseases; Female; Humans; Idoxuridin

1983
Serum concentrations of amiodarone during long term therapy. Relation to dose, efficacy and toxicity.
    European journal of clinical pharmacology, 1983, Volume: 24, Issue:4

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Corneal Diseases; Eye Diseases; Female;

1983
Drug induced ocular lipoidosis.
    Transactions of the Ophthalmological Society of New Zealand, 1982, Volume: 34

    Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Cataract; Color Vision Defects; Corneal Diseases;

1982
Amiodarone and dysthyroid eye disease.
    The British journal of ophthalmology, 1996, Volume: 80, Issue:9

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Eye Diseases; Humans; Male; Thyroid Diseases

1996
Amiodarone after myocardial infarction: EMIAT and CAMIAT trials.
    Lancet (London, England), 1997, Jun-14, Volume: 349, Issue:9067

    Topics: Amiodarone; Anti-Arrhythmia Agents; Clinical Trials as Topic; Eye Diseases; Humans; Lung Diseases

1997
Ocular toxicity of systemic medications: a case series.
    Optometry (St. Louis, Mo.), 2000, Volume: 71, Issue:1

    Topics: Adult; Aged; Amiodarone; Cataract; Corneal Diseases; Eye Diseases; Female; Glaucoma; Humans; Isoniaz

2000
From unwanted side-effects of drugs to an ophthalmological pharmacotherapy.
    Bulletin de la Societe belge d'ophtalmologie, 1977, Sep-17, Volume: 178

    Topics: Amiodarone; Eye Diseases; Humans; Iatrogenic Disease; Registries

1977
Drugs affecting the eye.
    Australian family physician, 1985, Volume: 14, Issue:8

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Amiodarone; Anti-Inflammatory Agents; Antipsychotic Agen

1985
[Adverse effects during chronic treatment with low-dose amiodarone].
    La Clinica terapeutica, 1985, Jul-15, Volume: 114, Issue:1

    Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Child; Drug Interactions; Eye Diseases;

1985
[Recurrent alveolitis caused by amiodarone].
    Giornale italiano di cardiologia, 1986, Volume: 16, Issue:2

    Topics: Amiodarone; Benzofurans; Eye Diseases; Female; Humans; Hyperthyroidism; Hypothyroidism; Middle Aged;

1986