amiodarone has been researched along with Extrasystole, Ventricular in 28 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To explore the therapeutic effects of amiodarone and metoprolol, either alone or in combination, on chronic heart failure (CHF) complicated by ventricular arrhythmia." | 9.14 | [Therapeutic effects of amiodarone and metoprolol on chronic heart failure complicated by ventricular arrhythmia]. ( He, BB; Huang, GH; Lü, HS, 2009) |
| "Amiodarone reduces the incidence of ventricular fibrillation or arrhythmic death among survivors of acute myocardial infarction with frequent or repetitive VPDs." | 9.08 | Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators. ( Cairns, JA; Connolly, SJ; Gent, M; Roberts, R, 1997) |
| "To evaluate the usefulness of Doppler parameters in the differentiation between the two types of amiodarone-associated thyrotoxicosis (AAT)." | 7.74 | Differentiation between the two types of amiodarone-associated thyrotoxicosis using duplex and amplitude Doppler sonography. ( Cerri, GG; Chammas, MC; Farage, L; Jorge, PT; Macedo, TA; Santos, VA; Souza, LP; Watanabe, T, 2007) |
| "We report the case of a 60 year old female patient on continuous systemic anticoagulation therapy with coumarin due to mechanical aortic valve replacement and a more than 3 years lasting amiodarone therapy due to severe ventricular extrasystoles suffering from amiodarone induced thyrotoxicosis (AIT)." | 7.74 | Impact of thyroid metabolism on the course of INR levels in a patient with systemic anticoagulation suffering from amiodarone-induced thyrotoxicosis. ( Biersack, HJ; Brockmann, H; Bucerius, J; Ezziddin, S; Palmedo, H, 2007) |
| "In 232 Japanese patients receiving long-term amiodarone therapy for life-threatening ventricular tachyarrhythmias, hyperthyroidism and hypothyroidism developed in 29 patients (12." | 7.71 | Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan. ( Hagiwara, N; Kasanuki, H; Matsuda, N; Sato, K; Shiga, T; Shoda, M; Wakaumi, M, 2001) |
| "The medical records, including radiographic imaging, pathology and operative reports, of 2 postpubertal boys who had sterile epididymitis after prolonged therapy with amiodarone were reviewed." | 7.70 | Amiodarone induced epididymitis in children. ( Diamond, DA; Hutcheson, J; Peters, CA, 1998) |
| "To explore the therapeutic effects of amiodarone and metoprolol, either alone or in combination, on chronic heart failure (CHF) complicated by ventricular arrhythmia." | 5.14 | [Therapeutic effects of amiodarone and metoprolol on chronic heart failure complicated by ventricular arrhythmia]. ( He, BB; Huang, GH; Lü, HS, 2009) |
| "Amiodarone reduces the incidence of ventricular fibrillation or arrhythmic death among survivors of acute myocardial infarction with frequent or repetitive VPDs." | 5.08 | Randomised trial of outcome after myocardial infarction in patients with frequent or repetitive ventricular premature depolarisations: CAMIAT. Canadian Amiodarone Myocardial Infarction Arrhythmia Trial Investigators. ( Cairns, JA; Connolly, SJ; Gent, M; Roberts, R, 1997) |
| "Sofosbuvir is a direct-acting antiviral drug used to treat chronic hepatitis C infection." | 3.85 | Ventricular Extrasystoles after First Dose of Sofosbuvir in a Patient Treated with Propranolol but not with Amiodarone: A Case Report. ( Baghazza, S; Bencherif, R; Chaabna, K; Djezzar, S; Guehimeche, R; Mallem, D; Rouabhia, S; Sadelaoud, M; Sadouki, H, 2017) |
| "To evaluate the usefulness of Doppler parameters in the differentiation between the two types of amiodarone-associated thyrotoxicosis (AAT)." | 3.74 | Differentiation between the two types of amiodarone-associated thyrotoxicosis using duplex and amplitude Doppler sonography. ( Cerri, GG; Chammas, MC; Farage, L; Jorge, PT; Macedo, TA; Santos, VA; Souza, LP; Watanabe, T, 2007) |
| "We report the case of a 60 year old female patient on continuous systemic anticoagulation therapy with coumarin due to mechanical aortic valve replacement and a more than 3 years lasting amiodarone therapy due to severe ventricular extrasystoles suffering from amiodarone induced thyrotoxicosis (AIT)." | 3.74 | Impact of thyroid metabolism on the course of INR levels in a patient with systemic anticoagulation suffering from amiodarone-induced thyrotoxicosis. ( Biersack, HJ; Brockmann, H; Bucerius, J; Ezziddin, S; Palmedo, H, 2007) |
| "To analyze action of digoxin and some non-digitalis drugs (beta-blockers, verapamil, amiodarone, d,l-sotalol) and their combinations on electrical activity of atria, frequency and structure of ventricular rhythm in patients with permanent atrial fibrillation." | 3.72 | [Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach]. ( Blagova, OV; Bogdanova, EA; Nedostup, AV; Platonova, AA, 2004) |
| "In 232 Japanese patients receiving long-term amiodarone therapy for life-threatening ventricular tachyarrhythmias, hyperthyroidism and hypothyroidism developed in 29 patients (12." | 3.71 | Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan. ( Hagiwara, N; Kasanuki, H; Matsuda, N; Sato, K; Shiga, T; Shoda, M; Wakaumi, M, 2001) |
| "The medical records, including radiographic imaging, pathology and operative reports, of 2 postpubertal boys who had sterile epididymitis after prolonged therapy with amiodarone were reviewed." | 3.70 | Amiodarone induced epididymitis in children. ( Diamond, DA; Hutcheson, J; Peters, CA, 1998) |
| "Nonsustained ventricular tachycardia is frequently seen in patients with heart failure and may be associated with worsened survival by univariate analysis." | 2.69 | Prevalence and significance of nonsustained ventricular tachycardia in patients with premature ventricular contractions and heart failure treated with vasodilator therapy. Department of Veterans Affairs CHF STAT Investigators. ( Carson, PE; Fisher, SG; Fletcher, RD; Singh, SN, 1998) |
| " The comprehensive test of the incidence of adverse reactions in relation to the two drugs resulted in an OR of 1." | 2.46 | [Efficacy and safety of amiodarone and metoprolol in the treatment of ventricular premature beats: a meta-analysis]. ( Huang, ZJ; Li, T; Li, YL; Wu, YL; Yang, MQ, 2010) |
| "Polymorphic ventricular tachycardia (VT) without QT prolongation is well described in patients without structural heart disease (mainly idiopathic ventricular fibrillation and Brugada syndrome) and in patients with acute ST-elevation myocardial infarction." | 1.51 | Quinidine-Responsive Polymorphic Ventricular Tachycardia in Patients With Coronary Heart Disease. ( Amit, G; Asher, E; Belhassen, B; Chorin, E; Halkin, A; Havakuk, O; Hochstadt, A; Laish-Farkash, A; Lee, JK; Rosso, R; Tovia-Brodie, O; Viskin, D; Viskin, S, 2019) |
| "Amiodarone is an effective treatment for atrial and ventricular arrhythmias, but its use is limited by a toxic adverse-effect profile." | 1.39 | Ventricular ectopy and QTc-interval prolongation associated with dronedarone therapy. ( Gonzalez, JE; Krantz, MJ; Sauer, WH, 2013) |
| "The number of premature ventricular complexes (PVCs)/min for each of the 20 minutes preceding the onset of ventricular tachyarrhythmia, the shortest coupling intervals between PVC and normal sinus beat, and the presence of short-long-short (SLS) interval sequences were examined." | 1.32 | Study of precursors of ventricular tachycardia from data stored in the memory of a dual chamber implantable cardioverter defibrillator. ( Iscolo, N; Kacet, S; Lavergne, T; Leenhardt, A; Mabo, P; Sadoul, N; Saoudi, N, 2003) |
| "Amiodarone is a useful drug for the treatment of life-threatening cardiac arrhythmias." | 1.31 | Serum KL-6 as a possible marker for amiodarone-induced pulmonary toxicity. ( Kawahara, Y; Matsushima, T; Miyashita, N; Nakajima, M; Niki, Y; Yoshida, K, 2000) |
| "In 5 patients with frequent premature ventricular ectopic beats, refractory to other antiarrhythmic treatments, amiodarone, given orally at the dose of 200 mg once a day for 4 weeks, reduced beta-adrenoceptor density from 202." | 1.28 | [The reduction of beta-adrenoceptor density and the suppression of ectopic ventricular activity with low doses of amiodarone]. ( Brevetti, G; Cutillo, E; D'Ascia, C; Farace, MJ; Leone, R; Perna, S; Picardi, G, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (25.00) | 18.2507 |
| 2000's | 9 (32.14) | 29.6817 |
| 2010's | 10 (35.71) | 24.3611 |
| 2020's | 2 (7.14) | 2.80 |
| Authors | Studies |
|---|---|
| Arias, MA | 1 |
| Pachón, M | 1 |
| Loughlin, G | 1 |
| Zizzo, G | 1 |
| Caruso, S | 1 |
| Ricchiuti, E | 1 |
| Turato, R | 1 |
| Stefani, I | 1 |
| Mazzone, A | 1 |
| Rouabhia, S | 1 |
| Baghazza, S | 1 |
| Sadouki, H | 1 |
| Djezzar, S | 1 |
| Bencherif, R | 1 |
| Guehimeche, R | 1 |
| Sadelaoud, M | 1 |
| Mallem, D | 1 |
| Chaabna, K | 1 |
| Viskin, S | 1 |
| Chorin, E | 1 |
| Viskin, D | 1 |
| Hochstadt, A | 1 |
| Halkin, A | 1 |
| Tovia-Brodie, O | 1 |
| Lee, JK | 1 |
| Asher, E | 1 |
| Laish-Farkash, A | 1 |
| Amit, G | 1 |
| Havakuk, O | 1 |
| Belhassen, B | 1 |
| Rosso, R | 1 |
| Gonzalez, JE | 1 |
| Sauer, WH | 1 |
| Krantz, MJ | 1 |
| Alexandre, J | 1 |
| Rouet, R | 1 |
| Puddu, PE | 1 |
| Beygui, F | 1 |
| Manrique, A | 1 |
| Milliez, P | 1 |
| Páez, JL | 1 |
| Doiny, D | 1 |
| Estrada, A | 1 |
| Figueroa, J | 1 |
| Filgueiras-Rama, D | 1 |
| Merino, JL | 1 |
| Beckermann, TM | 1 |
| McLeod, K | 1 |
| Murday, V | 1 |
| Potet, F | 1 |
| George, AL | 1 |
| Amin, AS | 1 |
| Cadrin-Tourigny, J | 1 |
| Fournier, A | 1 |
| Andelfinger, G | 1 |
| Khairy, P | 1 |
| Lü, HS | 1 |
| He, BB | 1 |
| Huang, GH | 1 |
| Huang, ZJ | 1 |
| Li, T | 1 |
| Yang, MQ | 1 |
| Wu, YL | 1 |
| Li, YL | 1 |
| Nebojša, M | 1 |
| Dragan, S | 1 |
| Nebojša, A | 1 |
| Tamara, A | 1 |
| Schamroth, CL | 1 |
| García Alberola, A | 1 |
| Gómez Agüera, A | 1 |
| Sánchez Muñoz, JJ | 1 |
| Martínez Sánchez, J | 1 |
| Llamas Lázaro, C | 1 |
| Valdés Chávarri, M | 1 |
| Leenhardt, A | 1 |
| Sadoul, N | 1 |
| Mabo, P | 1 |
| Kacet, S | 1 |
| Lavergne, T | 1 |
| Saoudi, N | 1 |
| Iscolo, N | 1 |
| Nedostup, AV | 1 |
| Blagova, OV | 1 |
| Bogdanova, EA | 1 |
| Platonova, AA | 1 |
| Macedo, TA | 1 |
| Chammas, MC | 1 |
| Jorge, PT | 1 |
| Souza, LP | 1 |
| Farage, L | 1 |
| Watanabe, T | 1 |
| Santos, VA | 1 |
| Cerri, GG | 1 |
| Bucerius, J | 1 |
| Ezziddin, S | 1 |
| Brockmann, H | 1 |
| Palmedo, H | 1 |
| Biersack, HJ | 1 |
| Perna, S | 1 |
| Leone, R | 1 |
| Farace, MJ | 1 |
| Cutillo, E | 1 |
| D'Ascia, C | 1 |
| Picardi, G | 1 |
| Brevetti, G | 1 |
| Cairns, JA | 1 |
| Connolly, SJ | 1 |
| Roberts, R | 1 |
| Gent, M | 1 |
| Duffee, DF | 1 |
| Shen, WK | 1 |
| Smith, HC | 1 |
| Hutcheson, J | 1 |
| Peters, CA | 1 |
| Diamond, DA | 1 |
| Tresch, DD | 1 |
| Thakur, RK | 1 |
| Singh, SN | 1 |
| Fisher, SG | 1 |
| Carson, PE | 1 |
| Fletcher, RD | 1 |
| Lane, J | 1 |
| Van Hare, GF | 1 |
| Nakajima, M | 1 |
| Kawahara, Y | 1 |
| Yoshida, K | 1 |
| Miyashita, N | 1 |
| Niki, Y | 1 |
| Matsushima, T | 1 |
| Shiga, T | 1 |
| Wakaumi, M | 1 |
| Matsuda, N | 1 |
| Shoda, M | 1 |
| Hagiwara, N | 1 |
| Sato, K | 1 |
| Kasanuki, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Acute Mechanical Response to Anti-arrhythmic Drug Therapy[NCT02575534] | 0 participants (Actual) | Interventional | 2015-10-31 | Withdrawn (stopped due to No enrollment in study.) | |||
| Catheter Ablation for Ventricular Tachycardia in Patients With an Implantable Cardioverter Defibrillator (CALYPSO) PILOT TRIAL[NCT01576042] | 27 participants (Actual) | Interventional | 2012-05-31 | Terminated (stopped due to Main objectives of the study were met; consensus among investigators that continuing the study would not add new information beyond that already learned.) | |||
| Reversal of Cardiomyopathy by Suppression of Frequent Premature Ventricular Complexes - A Prospective Randomized Clinical Trial[NCT01566344] | 70 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Records participants hospitalized for VT during the study (NCT01576042)
Timeframe: Baseline, 6 months
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 5 |
| Antiarrhythmic Medication | 7 |
Records participants who completed Month 3 Follow-Up Visit (NCT01576042)
Timeframe: 3 months
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 11 |
| Antiarrhythmic Medication | 12 |
Records participants who completed Month 6 Follow-Up Visit (NCT01576042)
Timeframe: 6 Months
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 7 |
| Antiarrhythmic Medication | 10 |
Records participants who had at least one of the efficacy outcome measurement (including death, hospitalization due to VT) (NCT01576042)
Timeframe: 6 Months
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 11 |
| Antiarrhythmic Medication | 14 |
Records participants who received study randomized treatment during the study (NCT01576042)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 11 |
| Antiarrhythmic Medication | 14 |
Records participants who only received study treatment as randomized during the entire study (NCT01576042)
Timeframe: 6 month
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 6 |
| Antiarrhythmic Medication | 13 |
Records participants who received study treatment as randomized and later switched to other treatment arm during the study (NCT01576042)
Timeframe: 6 months
| Intervention | participants (Number) |
|---|---|
| Catheter Ablation | 5 |
| Antiarrhythmic Medication | 1 |
Days from the date of the first study treatment to the date of first ICD recurrent therapy for VT. (NCT01576042)
Timeframe: Baseline, 6 months
| Intervention | Days (Mean) |
|---|---|
| Catheter Ablation | 70.1 |
| Antiarrhythmic Medication | 78.7 |
2 reviews available for amiodarone and Extrasystole, Ventricular
| Article | Year |
|---|---|
[Efficacy and safety of amiodarone and metoprolol in the treatment of ventricular premature beats: a meta-analysis].
Topics: Amiodarone; Drug Therapy, Combination; Humans; Metoprolol; Treatment Outcome; Ventricular Premature | 2010 |
Ventricular arrhythmias in the elderly.
Topics: Aged; Aged, 80 and over; Amiodarone; Angioplasty, Balloon, Coronary; Anti-Arrhythmia Agents; Coronar | 1998 |
3 trials available for amiodarone and Extrasystole, Ventricular
23 other studies available for amiodarone and Extrasystole, Ventricular
| Article | Year |
|---|---|
New Onset Recurrent Syncope Triggered by Fever.
Topics: Amiodarone; Coronary Angiography; Drug Therapy, Combination; Electric Countershock; Electrocardiogra | 2020 |
Amiodarone-induced organizing pneumonia mimicking COVID-19: a case report.
Topics: Aged; Amiodarone; COVID-19; Cryptogenic Organizing Pneumonia; Diagnosis, Differential; Humans; Male; | 2021 |
Ventricular Extrasystoles after First Dose of Sofosbuvir in a Patient Treated with Propranolol but not with Amiodarone: A Case Report.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antiviral Agents; Dose-Response Relationship, Drug; Echoca | 2017 |
Quinidine-Responsive Polymorphic Ventricular Tachycardia in Patients With Coronary Heart Disease.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Artery Disease; Drug Evaluation; Drug Resistance; | 2019 |
Ventricular ectopy and QTc-interval prolongation associated with dronedarone therapy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Electrocardiography, Amb | 2013 |
Dronedarone versus amiodarone in preventing premature ventricular contractions in an in vitro model of "border zone".
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Dronedarone; Electroc | 2014 |
Dronedarone: an option in the treatment of ventricular arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Dronedarone; Humans; Hypertension; | 2013 |
Novel SCN5A mutation in amiodarone-responsive multifocal ventricular ectopy-associated cardiomyopathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathies; DNA; DNA Mutational Analysis; Electrocardiogra | 2014 |
SCN5A-related dilated cardiomyopathy: what do we know?
Topics: Amiodarone; Cardiomyopathies; DNA; Female; Humans; Male; Mutation; NAV1.5 Voltage-Gated Sodium Chann | 2014 |
Severe left ventricular dysfunction in infants with ventricular preexcitation.
Topics: Adrenergic alpha-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Carbazoles; Cardiomyopathy, Dilate | 2008 |
Lethal outcome after intravenous administration of amiodarone in patient with atrial fibrillation and ventricular preexcitation.
Topics: Adult; Amiodarone; Atrial Fibrillation; Fatal Outcome; Humans; Infusions, Intravenous; Male; Ventric | 2011 |
The perils of pharmacological treatment for obesity: a case of sibutramine-associated cardiomyopathy and malignant arrhythmias.
Topics: Amiodarone; Anti-Arrhythmia Agents; Appetite Depressants; Cardiomyopathy, Hypertrophic; Cyclobutanes | 2012 |
[Transient atrial fibrillation induced by adenosine in a patient with atrial tachycardia].
Topics: Adenosine; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Electrocardiography; Female; Hum | 2002 |
Study of precursors of ventricular tachycardia from data stored in the memory of a dual chamber implantable cardioverter defibrillator.
Topics: Amiodarone; Anti-Arrhythmia Agents; Defibrillators, Implantable; Female; Humans; Male; Middle Aged; | 2003 |
[Correction of rate and structure of ventricular rhythm in permanent atrial fibrillation: a novel pathogenetic approach].
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Digoxin; Electrocardi | 2004 |
Differentiation between the two types of amiodarone-associated thyrotoxicosis using duplex and amplitude Doppler sonography.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Area Under Curve; Atrial Fibrill | 2007 |
Impact of thyroid metabolism on the course of INR levels in a patient with systemic anticoagulation suffering from amiodarone-induced thyrotoxicosis.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Coumarins; Female; Humans; International Normali | 2007 |
[The reduction of beta-adrenoceptor density and the suppression of ectopic ventricular activity with low doses of amiodarone].
Topics: Adult; Amiodarone; Analysis of Variance; Dose-Response Relationship, Drug; Drug Evaluation; Female; | 1992 |
Suppression of frequent premature ventricular contractions and improvement of left ventricular function in patients with presumed idiopathic dilated cardiomyopathy.
Topics: Adrenergic beta-Antagonists; Aged; Amiodarone; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhyt | 1998 |
Amiodarone induced epididymitis in children.
Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Child; Death, Sudden, Ca | 1998 |
Paroxysmal long RP tachycardia in a three year old: what is the rhythm?
Topics: Amiodarone; Anti-Arrhythmia Agents; Child, Preschool; Diagnosis, Differential; Electrocardiography; | 1999 |
Serum KL-6 as a possible marker for amiodarone-induced pulmonary toxicity.
Topics: Amiodarone; Anti-Arrhythmia Agents; Antigens; Antigens, Neoplasm; Biomarkers; Carbon Monoxide; Cardi | 2000 |
Amiodarone-Induced thyroid dysfunction and ventricular tachyarrhythmias during long-term therapy in Japan.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Drug Evaluation; Female; Follow-Up Studies; Humans; H | 2001 |