amiodarone has been researched along with Enlarged Liver in 3 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Amiodarone is an effective antiarrhythmic agent for preventing and treating atrial and ventricular arrhythmias." | 2.44 | Fatal amiodarone-induced hepatotoxicity: a case report and literature review. ( Chan, AL; Hsieh, HJ; Hsieh, YA; Lin, SJ, 2008) |
| "Amiodarone induced hepatomegaly, hepatocyte microvesicular lipid accumulation, and a significant decrease in serum triglycerides and glucose." | 1.32 | Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation. ( Hanniman, EA; McCarthy, TC; Pollak, PT; Sinal, CJ, 2004) |
| " These findings suggest that both toxic and hypersensitivity liver injury can occur in response to amiodarone." | 1.27 | Amiodarone hepatotoxicity. A clinicopathologic study of five patients. ( Barwick, KW; Batsford, WP; Enriquez, R; Helzberg, J; Josephson, ME; Riely, CA; Rigas, B; Rosenfeld, LE, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| McCarthy, TC | 1 |
| Pollak, PT | 1 |
| Hanniman, EA | 1 |
| Sinal, CJ | 1 |
| Chan, AL | 1 |
| Hsieh, HJ | 1 |
| Hsieh, YA | 1 |
| Lin, SJ | 1 |
| Rigas, B | 1 |
| Rosenfeld, LE | 1 |
| Barwick, KW | 1 |
| Enriquez, R | 1 |
| Helzberg, J | 1 |
| Batsford, WP | 1 |
| Josephson, ME | 1 |
| Riely, CA | 1 |
1 review available for amiodarone and Enlarged Liver
| Article | Year |
|---|---|
Fatal amiodarone-induced hepatotoxicity: a case report and literature review.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Chemical and Drug Induced Liver Injur | 2008 |
2 other studies available for amiodarone and Enlarged Liver
| Article | Year |
|---|---|
Disruption of hepatic lipid homeostasis in mice after amiodarone treatment is associated with peroxisome proliferator-activated receptor-alpha target gene activation.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Blood Glucose; Blotting, Northern; Body Weight; Cell Li | 2004 |
Amiodarone hepatotoxicity. A clinicopathologic study of five patients.
Topics: Aged; Alanine Transaminase; Alkaline Phosphatase; Amiodarone; Aspartate Aminotransferases; Benzofura | 1986 |