amiodarone has been researched along with Electrocardiogram QT Prolonged in 78 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The Short-term AMIOdarone treatment after CATheter ablation for atrial fibrillation (AMIO-CAT) trial randomized patients to 8 weeks of oral amiodarone or placebo following AF ablation." | 9.30 | QT as a predictor of recurrence after atrial fibrillation ablation and the impact of amiodarone: results from the placebo-controlled AMIO-CAT trial. ( Chen, X; Darkner, S; Diederichsen, SZ; Hansen, J; Johannessen, A; Pehrson, S; Svendsen, JH, 2019) |
| " The patient was under amiodarone and sotalol therapy for atrial fibrillation, with no obvious QT prolongation prior to ciprofloxacin therapy." | 7.75 | Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy. ( Arnaoutoglou, C; Chrisopoulos, C; Keivanidou, A; Kirpizidis, C; Krommydas, A; Papanikolaou, G; Tsiptses, K, 2009) |
| "The response over time of the QT interval and the Transmural Dispersion of Repolarization (TDR) to Isoproterenol infusion (ISO) in an 85 year-old-man with severe and syntomatic bradycardia, in the setting of an Amiodarone-induced Long QT Syndrome (LQTS) is the subject of this communication." | 7.75 | Isoproterenol enhancement of I(Ks) current in amiodarone-induced long QT syndrome. ( Gutierrez, J; Raviña, M; Raviña, T, 2009) |
| "We describe full exposure of an acquired Long QT Syndrome (aLQTS) in an elderly female patient on long-term Amiodarone treatment." | 7.74 | Acquired long QT syndrome: Unequal regression of Amiodarone-induced repolarization lengthening. ( Gutierrez, J; Raviña, P; Raviña, T, 2008) |
| "Amiodarone is an effective antiarrhythmic drug rarely associated with torsade de pointes arrhythmias (TdP)." | 7.71 | Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome. ( de Groot, SH; Leunissen, JD; Molenschot, MM; Schoenmakers, M; van Der Hulst, FF; van Opstal, JM; Verduyn, SC; Vos, MA; Wellens, HJ, 2001) |
| " We report a case where these episodes were caused by recurrent ventricular tachycardia/ventricular fibrillation secondary to idiopathic long QT syndrome which was effectively treated with amiodarone." | 7.68 | Effective management of long Q-T syndrome with amiodarone. ( Ainon, S; Gururaj, AK, 1990) |
| "The clinical efficacy of amiodarone in the management of patients with complex cardiac arrhythmias refractory to therapy with two or more conventional or other investigational anti-arrhythmic agents was studied by long-term follow-up of patients who had received the drug for a period of at least three months." | 7.67 | Evaluation of amiodarone therapy in the treatment of drug-resistant cardiac arrhythmias: long term follow-up. ( Hamer, A; Mandel, WJ; Peter, T, 1985) |
| "Long QT syndrome is characterized by electrocardiographic appearance of long QT intervals and propensity to polymorphic ventricular tachycardia." | 5.38 | A neonate with long QT syndrome, refractory ventricular arrhythmias, and lidocaine toxicity. ( Montenegro, LM; Naim, M; Nathan, AT; Vetter, VL, 2012) |
| "A 70-year-old woman with dilated cardiomyopathy and ventricular tachyarrhythmia was initially treated in 1990 with intravenous amiodarone (240 mg)." | 5.31 | Torsade de pointes induced by intravenous and long-term oral amiodarone therapy in a patient with dilated cardiomyopathy. ( Kuga, K; Yamada, S; Yamaguchi, I, 2001) |
| "The Short-term AMIOdarone treatment after CATheter ablation for atrial fibrillation (AMIO-CAT) trial randomized patients to 8 weeks of oral amiodarone or placebo following AF ablation." | 5.30 | QT as a predictor of recurrence after atrial fibrillation ablation and the impact of amiodarone: results from the placebo-controlled AMIO-CAT trial. ( Chen, X; Darkner, S; Diederichsen, SZ; Hansen, J; Johannessen, A; Pehrson, S; Svendsen, JH, 2019) |
| "This study assesses the effects of dofetilide, a new selective Ikr blocker with class III properties, on left ventricular function and hemodynamics of heart failure and compares these effects with those of placebo and amiodarone." | 5.09 | Cardiac and hemodynamic effects of intravenous dofetilide in patients with heart failure. ( Ahn, S; Etienne, J; Friedrich, T; Ghadanfar, M; Massart, PE; Pouleur, H; Rousseau, MF; van Eyll, C, 2001) |
| "Although amiodarone appears to have few pro-arrhythmic effects, torsade de pointes (TdP) has been observed after administration of a low dose and short term use of oral amiodarone, in the absence of predisposing factors." | 3.80 | Intermittent QT prolongation induced by short-term oral amiodarone therapy. ( Amasyalı, B; Astarcioglu, MA; Durmuş, HI; Sen, T, 2014) |
| " We present the case of 52-year-old male who was treated with clarithromycin due to bilateral atypical pneumonia." | 3.80 | Cardiac arrest and electrical storm due to recurrent torsades de pointes caused by concomitant clarithromycin, cotrimoxazole and amiodarone treatment. ( Bienias, P; Ciurzyński, M; Paczyńska, M; Pruszczyk, P, 2014) |
| " The patient was under amiodarone and sotalol therapy for atrial fibrillation, with no obvious QT prolongation prior to ciprofloxacin therapy." | 3.75 | Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy. ( Arnaoutoglou, C; Chrisopoulos, C; Keivanidou, A; Kirpizidis, C; Krommydas, A; Papanikolaou, G; Tsiptses, K, 2009) |
| "The response over time of the QT interval and the Transmural Dispersion of Repolarization (TDR) to Isoproterenol infusion (ISO) in an 85 year-old-man with severe and syntomatic bradycardia, in the setting of an Amiodarone-induced Long QT Syndrome (LQTS) is the subject of this communication." | 3.75 | Isoproterenol enhancement of I(Ks) current in amiodarone-induced long QT syndrome. ( Gutierrez, J; Raviña, M; Raviña, T, 2009) |
| "We describe full exposure of an acquired Long QT Syndrome (aLQTS) in an elderly female patient on long-term Amiodarone treatment." | 3.74 | Acquired long QT syndrome: Unequal regression of Amiodarone-induced repolarization lengthening. ( Gutierrez, J; Raviña, P; Raviña, T, 2008) |
| "This report documents the occurrence of torsades de pointes (TdP) caused by marked QT interval prolongation in the case of a 71-year-old woman receiving both metronidazole and amiodarone for the treatment of pseudomembranous colitis and paroxysmal atrial fibrillation." | 3.73 | QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone. ( Efraimidis, M; Kardaras, F; Kounas, SP; Letsas, KP; Sideris, A, 2005) |
| " Suddenly on the 6th day of the so far uncomplicated AMI ventricular fibrillation developed and was successfully treated with DC shock, and amiodarone (150 mg i." | 3.73 | [Polymorphic ventricular tachycardia in acute myocardial infarction without ST elevation in a patient with thrombocytopenia]. ( Bromblik, A; Bryniarski, L; Czamara, M; Dragan, J; Kukla, P; Szczuka, K; Słowiak-Lewińska, T, 2006) |
| "Comparing patients treated after myocardial infarction with amiodarone or with placebo, we found a significant rate-dependent prolongation of TpTe interval in patients who received amiodarone." | 3.72 | Effect of amiodarone on the descending limb of the T wave. ( Batchvarov, V; Camm, AJ; Hnatkova, K; Malik, M; Pueyo, E; Smetana, P, 2003) |
| "Amiodarone is an effective antiarrhythmic drug rarely associated with torsade de pointes arrhythmias (TdP)." | 3.71 | Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome. ( de Groot, SH; Leunissen, JD; Molenschot, MM; Schoenmakers, M; van Der Hulst, FF; van Opstal, JM; Verduyn, SC; Vos, MA; Wellens, HJ, 2001) |
| " We report a case where these episodes were caused by recurrent ventricular tachycardia/ventricular fibrillation secondary to idiopathic long QT syndrome which was effectively treated with amiodarone." | 3.68 | Effective management of long Q-T syndrome with amiodarone. ( Ainon, S; Gururaj, AK, 1990) |
| "Torsade de pointes may occur as a complication of amiodarone therapy." | 3.68 | Sudden cardiac death while taking amiodarone therapy: the role of abnormal repolarization. ( Lopes, A; Morgan, JM; Rowland, E, 1991) |
| " Individual differences between the longest and the shortest RV MAP durations indicate that: normally (40 subjects) ventricular repolarization is almost synchronous; QT prolongation due either to bradycardia or to amiodarone treatment (eight cases) may be the result of a uniform lengthening of ventricular repolarization, when ventricular arrhythmias are not present; in long QT syndromes (LQTSs) of differing etiology (10 cases), in which severe ventricular arrhythmias are present, marked individual differences in RV MAP duration are present and correspond with pathological asynchrony of ventricular repolarization." | 3.67 | Monophasic action potential studies in human subjects with prolonged ventricular repolarization and long QT syndromes. ( Bonatti, V; Botti, G; Rolli, A, 1985) |
| "The clinical efficacy of amiodarone in the management of patients with complex cardiac arrhythmias refractory to therapy with two or more conventional or other investigational anti-arrhythmic agents was studied by long-term follow-up of patients who had received the drug for a period of at least three months." | 3.67 | Evaluation of amiodarone therapy in the treatment of drug-resistant cardiac arrhythmias: long term follow-up. ( Hamer, A; Mandel, WJ; Peter, T, 1985) |
| " Recent studies have also demonstrated increased morbidity and mortality with the use of digoxin and other AAD which interact with P-gp." | 2.82 | Drug Interactions Affecting Antiarrhythmic Drug Use. ( Chung, MK; Dukes, JW; Ezekowitz, M; Gopinathannair, R; Horbal, P; Lakkireddy, D; Lip, GYH; Mar, PL; Miletello, M; Noseworthy, PA; Olshansky, B; Reiffel, JA; Tisdale, JE, 2022) |
| "In 32 subjects, 10 with postischemic dilated cardiomyopathy, 12 with hypertensive cardiomyopathy, and 10 healthy, we assessed QT(c) and QT variability index (QTVI) after administration of fresh pink grapefruit juice, placebo, amiodarone, or sotalol." | 2.73 | Effects of pink grapefruit juice on QT variability in patients with dilated or hypertensive cardiomyopathy and in healthy subjects. ( Ghiselli, A; Magnanti, M; Magrì, D; Marigliano, V; Matera, S; Mitra, M; Paroli, M; Pasquazzi, E; Piccirillo, G; Schifano, E; Velitti, S, 2008) |
| " Despite careful precautions, serious proarrhythmias, the major limiting side effect of dofetilide, still occurred during long-term follow-up." | 2.73 | Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function. ( Bauman, JL; Kehoe, RF; Leal, S; Mykytsey, A; Razminia, M; Saleem, M; Wang, T; Zheutlin, T, 2007) |
| "Amiodarone is widely used in ventricular tachyarrhythmias and atrial fibrillation, known to prolong QT-intervals." | 2.71 | Iohexol contrast medium induces QT prolongation in amiodarone patients. ( Figulla, HR; Goernig, M; Hartog, CS; Kirmeier, T; Krack, A; Leder, U, 2004) |
| "However, QTc monitoring in bundle branch block requires some modification as outlined in this case report." | 1.62 | Amiodarone in patients with left bundle branch block: how to assess the QT interval? ( Bandorski, D; Bogossian, H; Erkapic, D; Iliodromitis, K, 2021) |
| "Amiodarone treatment was stopped, and magnesium sulfate was infused." | 1.56 | Torsade de pointes in initiating hemodialysis: a case report. ( Bae, EH; Choi, HS; Kim, CS; Kim, SW; Ma, SK; Yang, JA, 2020) |
| "Amiodarone was the most prescribed drug with a definite risk of TdP." | 1.43 | Prevalence and Risk Factors Associated with Use of QT-Prolonging Drugs in Hospitalized Older People. ( Ardoino, I; Biganzoli, EM; Corrao, S; Franchi, C; Mannucci, PM; Marcucci, M; Marengoni, A; Nobili, A; Pasina, L; Rossio, R; Tettamanti, M, 2016) |
| "To determine the most common drug-drug interaction (DDI) pairs contributing to QTc prolongation in cardiac intensive care units (ICUs)." | 1.39 | Drug-drug interactions contributing to QT prolongation in cardiac intensive care units. ( Armahizer, MJ; Kane-Gill, SL; Seybert, AL; Smithburger, PL, 2013) |
| "Amiodarone is an effective treatment for atrial and ventricular arrhythmias, but its use is limited by a toxic adverse-effect profile." | 1.39 | Ventricular ectopy and QTc-interval prolongation associated with dronedarone therapy. ( Gonzalez, JE; Krantz, MJ; Sauer, WH, 2013) |
| "Long QT syndrome is characterized by electrocardiographic appearance of long QT intervals and propensity to polymorphic ventricular tachycardia." | 1.38 | A neonate with long QT syndrome, refractory ventricular arrhythmias, and lidocaine toxicity. ( Montenegro, LM; Naim, M; Nathan, AT; Vetter, VL, 2012) |
| "Flecainide is an antiarrhythmic drug that blocks sodium channels during phase 0 of cardiac action potential, delaying conduction and reducing contractility." | 1.36 | [Flecainide poisoning]. ( Bobillo, B; Diz Gómez, JC; Doniz Campos, M; Filgueira, P; Illodo Miramontes, G; Otero Amoedo, T; Rey López, F, 2010) |
| "In amiodarone-treated, hypokalemic hearts, no EAD or TdP occurred." | 1.32 | Comparison of the in vitro electrophysiologic and proarrhythmic effects of amiodarone and sotalol in a rabbit model of acute atrioventricular block. ( Breithardt, G; Eckardt, L; Haverkamp, W; Milberg, P; Mönnig, G; Osada, N; Ramtin, S; Wasmer, K, 2004) |
| "A 70-year-old woman with dilated cardiomyopathy and ventricular tachyarrhythmia was initially treated in 1990 with intravenous amiodarone (240 mg)." | 1.31 | Torsade de pointes induced by intravenous and long-term oral amiodarone therapy in a patient with dilated cardiomyopathy. ( Kuga, K; Yamada, S; Yamaguchi, I, 2001) |
| "D-sotalol was added to the perfusion medium at a concentration of 4 micrograms ml-1, while amiodarone was administered, before in vitro evaluation, for seven days (50 mg kg-1 per day, intraperitoneally)." | 1.30 | Adaptation of the QT interval to heart rate changes in isolated perfused guinea pig heart: influence of amiodarone and D-sotalol. ( Antolini, R; Bova, S; Ferrari, M; Nollo, G; Padrini, R; Piovan, D; Speranza, G, 1997) |
| "Association of long QT with arrhythmia does not, therefore, invalidate the principle that homogeneously prolonged APD should be anti-arrhythmic." | 1.27 | Delayed ventricular repolarization as an anti-arrhythmic principle. ( Vaughan Williams, EM, 1985) |
| "Amiodarone was used for recurrent supraventricular tachycardia in four cases and frequent ventricular extra systoles complicating congenital QT prolongation in the remaining case." | 1.27 | Amiodarone-induced torsades de pointes. ( Brown, MA; Lubbe, WF; Norris, RM; Smith, WM, 1986) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (10.26) | 18.7374 |
| 1990's | 5 (6.41) | 18.2507 |
| 2000's | 34 (43.59) | 29.6817 |
| 2010's | 26 (33.33) | 24.3611 |
| 2020's | 5 (6.41) | 2.80 |
| Authors | Studies |
|---|---|
| Iliodromitis, K | 1 |
| Erkapic, D | 1 |
| Bandorski, D | 1 |
| Bogossian, H | 1 |
| Mar, PL | 1 |
| Horbal, P | 1 |
| Chung, MK | 1 |
| Dukes, JW | 1 |
| Ezekowitz, M | 1 |
| Lakkireddy, D | 1 |
| Lip, GYH | 1 |
| Miletello, M | 1 |
| Noseworthy, PA | 1 |
| Reiffel, JA | 1 |
| Tisdale, JE | 1 |
| Olshansky, B | 1 |
| Gopinathannair, R | 1 |
| Yang, JA | 1 |
| Choi, HS | 1 |
| Bae, EH | 1 |
| Ma, SK | 1 |
| Kim, SW | 1 |
| Kim, CS | 1 |
| Beserra, SS | 1 |
| Santos-Miranda, A | 1 |
| Sarmento, JO | 1 |
| Miranda, VM | 1 |
| Roman-Campos, D | 1 |
| Lee, S | 1 |
| Kittleson, MD | 1 |
| Wei, A | 1 |
| Peng, J | 1 |
| Gu, Z | 1 |
| Li, J | 1 |
| Fernandes, FM | 1 |
| Silva, EP | 1 |
| Martins, RR | 1 |
| Oliveira, AG | 1 |
| Mourad, A | 1 |
| Stiber, JA | 1 |
| Perfect, JR | 1 |
| Johnson, MD | 1 |
| Diederichsen, SZ | 1 |
| Darkner, S | 1 |
| Chen, X | 1 |
| Johannessen, A | 1 |
| Pehrson, S | 1 |
| Hansen, J | 1 |
| Svendsen, JH | 1 |
| Gonzalez, JE | 1 |
| Sauer, WH | 1 |
| Krantz, MJ | 1 |
| Tarapués, M | 1 |
| Cereza, G | 1 |
| Arellano, AL | 1 |
| Montané, E | 1 |
| Figueras, A | 1 |
| Astarcioglu, MA | 1 |
| Durmuş, HI | 1 |
| Sen, T | 1 |
| Amasyalı, B | 1 |
| Snipelisky, D | 1 |
| Roberts, M | 1 |
| Blackshear, J | 1 |
| Bienias, P | 1 |
| Ciurzyński, M | 1 |
| Paczyńska, M | 1 |
| Pruszczyk, P | 1 |
| De Maria, E | 1 |
| Patrizi, G | 1 |
| Cappelli, S | 1 |
| Stiefelhagen, P | 1 |
| Buch, T | 1 |
| Andersen, SE | 1 |
| Franchi, C | 1 |
| Ardoino, I | 1 |
| Rossio, R | 1 |
| Nobili, A | 1 |
| Biganzoli, EM | 1 |
| Marengoni, A | 1 |
| Marcucci, M | 1 |
| Pasina, L | 1 |
| Tettamanti, M | 1 |
| Corrao, S | 1 |
| Mannucci, PM | 1 |
| Riera, AR | 1 |
| Uchida, AH | 1 |
| Ferreira, C | 1 |
| Ferreira Filho, C | 1 |
| Schapachnik, E | 1 |
| Dubner, S | 1 |
| Zhang, L | 1 |
| Moffa, PJ | 1 |
| Bush, SE | 1 |
| Hatton, RC | 1 |
| Winterstein, AG | 1 |
| Thomson, MR | 1 |
| Woo, GW | 1 |
| Keivanidou, A | 1 |
| Arnaoutoglou, C | 1 |
| Krommydas, A | 1 |
| Papanikolaou, G | 1 |
| Tsiptses, K | 1 |
| Chrisopoulos, C | 1 |
| Kirpizidis, C | 1 |
| Fishberger, SB | 1 |
| Hannan, RL | 1 |
| Welch, EM | 1 |
| Rossi, AF | 1 |
| Cherry, JG | 1 |
| Burger, CI | 1 |
| Clase, CM | 1 |
| Gangji, AS | 1 |
| Kuz'min, VS | 1 |
| Rozenshtraukh, LV | 1 |
| Doniz Campos, M | 1 |
| Illodo Miramontes, G | 1 |
| Bobillo, B | 1 |
| Otero Amoedo, T | 1 |
| Filgueira, P | 1 |
| Rey López, F | 1 |
| Diz Gómez, JC | 1 |
| Werner, CR | 1 |
| Riessen, R | 1 |
| Gregor, M | 1 |
| Bitzer, M | 1 |
| Fayssoil, A | 1 |
| Issi, J | 1 |
| Guerbaa, M | 1 |
| Raynaud, JC | 1 |
| Heroguelle, V | 1 |
| Digby, GC | 1 |
| Pérez Riera, AR | 1 |
| Barbosa Barros, R | 1 |
| Simpson, CS | 1 |
| Redfearn, DP | 1 |
| Methot, M | 1 |
| Femenía, F | 1 |
| Baranchuk, A | 1 |
| Milberg, P | 3 |
| Frommeyer, G | 2 |
| Uphaus, T | 1 |
| Kaiser, D | 1 |
| Osada, N | 3 |
| Breithardt, G | 3 |
| Eckardt, L | 4 |
| Pott, C | 1 |
| Fink, M | 1 |
| Ruhe, M | 1 |
| Matsuda, T | 1 |
| Baba, A | 1 |
| Klocke, R | 1 |
| Quang, TH | 1 |
| Nikol, S | 1 |
| Stypmann, J | 1 |
| Müller, FU | 1 |
| Noble, D | 1 |
| Morris, D | 1 |
| Cameron, N | 1 |
| Nathan, AT | 1 |
| Naim, M | 1 |
| Montenegro, LM | 1 |
| Vetter, VL | 1 |
| Jamshidi, Y | 1 |
| Nolte, IM | 1 |
| Dalageorgou, C | 1 |
| Zheng, D | 1 |
| Johnson, T | 1 |
| Bastiaenen, R | 1 |
| Ruddy, S | 1 |
| Talbott, D | 1 |
| Norris, KJ | 1 |
| Snieder, H | 1 |
| George, AL | 1 |
| Marshall, V | 1 |
| Shakir, S | 1 |
| Kannankeril, PJ | 1 |
| Munroe, PB | 1 |
| Camm, AJ | 2 |
| Jeffery, S | 1 |
| Roden, DM | 1 |
| Behr, ER | 1 |
| Chiladakis, J | 1 |
| Kalogeropoulos, A | 1 |
| Koutsogiannis, N | 1 |
| Zagkli, F | 1 |
| Vlassopoulou, N | 1 |
| Chouchoulis, K | 1 |
| Alexopoulos, D | 1 |
| Armahizer, MJ | 1 |
| Seybert, AL | 1 |
| Smithburger, PL | 1 |
| Kane-Gill, SL | 1 |
| Junker, J | 1 |
| Haverkamp, W | 2 |
| Schulze-Bahr, E | 1 |
| Paulus, W | 1 |
| Kiefer, R | 1 |
| Malfatto, G | 1 |
| Facchini, M | 1 |
| Zaza, A | 1 |
| Atar, S | 1 |
| Freedberg, NA | 1 |
| Antonelli, D | 1 |
| Rosenfeld, T | 1 |
| Smetana, P | 1 |
| Pueyo, E | 1 |
| Hnatkova, K | 1 |
| Batchvarov, V | 1 |
| Malik, M | 1 |
| Goernig, M | 1 |
| Kirmeier, T | 1 |
| Krack, A | 1 |
| Hartog, CS | 1 |
| Figulla, HR | 1 |
| Leder, U | 1 |
| Ramtin, S | 1 |
| Mönnig, G | 1 |
| Wasmer, K | 1 |
| Kounas, SP | 2 |
| Letsas, KP | 2 |
| Sideris, A | 2 |
| Efraimidis, M | 1 |
| Kardaras, F | 2 |
| Filippatos, GS | 1 |
| Efremidis, M | 1 |
| Somberg, J | 1 |
| Molnar, J | 1 |
| Kukla, P | 1 |
| Bryniarski, L | 1 |
| Dragan, J | 1 |
| Słowiak-Lewińska, T | 1 |
| Czamara, M | 1 |
| Bromblik, A | 1 |
| Szczuka, K | 1 |
| Tsiperfal, A | 1 |
| Hsia, H | 1 |
| Thompson, C | 1 |
| Raviña, T | 3 |
| Raviña, P | 1 |
| Gutierrez, J | 3 |
| Lehtonen, A | 1 |
| Fodstad, H | 1 |
| Laitinen-Forsblom, P | 1 |
| Toivonen, L | 1 |
| Kontula, K | 1 |
| Swan, H | 1 |
| Mykytsey, A | 1 |
| Bauman, JL | 1 |
| Razminia, M | 1 |
| Zheutlin, T | 1 |
| Wang, T | 1 |
| Saleem, M | 1 |
| Leal, S | 1 |
| Kehoe, RF | 2 |
| Mironchik, EV | 1 |
| Dolgosheĭ, TS | 1 |
| Liskovich, TG | 1 |
| Madeshkina, GA | 1 |
| Kokhkovski, AB | 1 |
| Tyshchenko, AD | 1 |
| Wu, L | 1 |
| Rajamani, S | 1 |
| Shryock, JC | 1 |
| Li, H | 1 |
| Ruskin, J | 1 |
| Antzelevitch, C | 1 |
| Belardinelli, L | 1 |
| Wegener, FT | 1 |
| Ehrlich, JR | 1 |
| Hohnloser, SH | 2 |
| Tsukada, YT | 1 |
| Kishida, H | 1 |
| Raviña, M | 1 |
| Piccirillo, G | 1 |
| Magrì, D | 1 |
| Matera, S | 1 |
| Magnanti, M | 1 |
| Pasquazzi, E | 1 |
| Schifano, E | 1 |
| Velitti, S | 1 |
| Mitra, M | 1 |
| Marigliano, V | 1 |
| Paroli, M | 1 |
| Ghiselli, A | 1 |
| van de Loo, A | 1 |
| Klingenheben, T | 1 |
| Padrini, R | 1 |
| Speranza, G | 1 |
| Nollo, G | 1 |
| Bova, S | 1 |
| Piovan, D | 1 |
| Antolini, R | 1 |
| Ferrari, M | 1 |
| Sheridan, DJ | 1 |
| Karaguezian, HS | 1 |
| Yamada, S | 1 |
| Kuga, K | 1 |
| Yamaguchi, I | 1 |
| Nkomo, VT | 1 |
| Shen, WK | 1 |
| Rousseau, MF | 1 |
| Massart, PE | 1 |
| van Eyll, C | 1 |
| Etienne, J | 1 |
| Ahn, S | 1 |
| Ghadanfar, M | 1 |
| Friedrich, T | 1 |
| Pouleur, H | 1 |
| Iannini, PB | 1 |
| van Opstal, JM | 1 |
| Schoenmakers, M | 1 |
| Verduyn, SC | 1 |
| de Groot, SH | 1 |
| Leunissen, JD | 1 |
| van Der Hulst, FF | 1 |
| Molenschot, MM | 1 |
| Wellens, HJ | 1 |
| Vos, MA | 1 |
| Tomcsányi, J | 1 |
| Somlói, M | 1 |
| Horváth, L | 1 |
| Morgan, JM | 1 |
| Lopes, A | 1 |
| Rowland, E | 1 |
| Gururaj, AK | 1 |
| Ainon, S | 1 |
| Rankin, AC | 1 |
| Pringle, SD | 1 |
| Cobbe, SM | 1 |
| Bonatti, V | 1 |
| Rolli, A | 1 |
| Botti, G | 1 |
| Vaughan Williams, EM | 1 |
| Lazzara, R | 1 |
| Mattioni, TA | 1 |
| Zheutlin, TA | 1 |
| Sarmiento, JJ | 1 |
| Parker, M | 1 |
| Lesch, M | 1 |
| Helmy, I | 1 |
| Herre, JM | 1 |
| Gee, G | 1 |
| Sharkey, H | 1 |
| Malone, P | 1 |
| Sauve, MJ | 1 |
| Griffin, JC | 1 |
| Scheinman, MM | 1 |
| Leroy, G | 1 |
| Haiat, R | 1 |
| Barthelemy, M | 1 |
| Lionnet, F | 1 |
| Brown, MA | 1 |
| Smith, WM | 1 |
| Lubbe, WF | 1 |
| Norris, RM | 1 |
| Peter, T | 1 |
| Hamer, A | 1 |
| Mandel, WJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Observational Study to Evaluate the Effects on the Qt Interval of COVID-19 Coronavirus Infection in Critically Ill Patients[NCT04422535] | 80 participants (Anticipated) | Observational | 2020-05-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for amiodarone and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Drug Interactions Affecting Antiarrhythmic Drug Use.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Arrhythmias, Cardiac; Drug Interactions; | 2022 |
QTc prolongation and torsades de pointes due to a coadministration of fluoxetine and amiodarone in a patient with implantable cardioverter-defibrillator: Case report and review of the literature.
Topics: Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Defibrillators, Implantable; Drug Inter | 2017 |
Relationship among amiodarone, new class III antiarrhythmics, miscellaneous agents and acquired long QT syndrome.
Topics: Action Potentials; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Long QT Syndrome | 2008 |
[Ionic mechanisms of action of class III antiarrhythmic drugs].
Topics: Amiodarone; Animals; Anisoles; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Dogs; Dronedarone; Elec | 2010 |
[Adverse effects of cardiovascular agents].
Topics: Amiodarone; Anti-Arrhythmia Agents; Anticoagulants; Brugada Syndrome; Drug Interactions; Fibrinolyti | 2007 |
Drug-induced proarrhythmic effects: assessment of changes in QT interval.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Electrophysiology; He | 2000 |
Amiodarone and torsade de pointes.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Electrocardiography; Humans; Long QT Syndr | 1989 |
5 trials available for amiodarone and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
QT as a predictor of recurrence after atrial fibrillation ablation and the impact of amiodarone: results from the placebo-controlled AMIO-CAT trial.
Topics: Administration, Oral; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Catheter Ablation; Co | 2019 |
Iohexol contrast medium induces QT prolongation in amiodarone patients.
Topics: Amiodarone; Anti-Arrhythmia Agents; Contrast Media; Humans; Iohexol; Long QT Syndrome; Retrospective | 2004 |
Observations on the safety and effectiveness of dofetilide in patients with paroxysmal atrial fibrillation and normal left ventricular function.
Topics: Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Flut | 2007 |
Effects of pink grapefruit juice on QT variability in patients with dilated or hypertensive cardiomyopathy and in healthy subjects.
Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Beverages; Cardiomyopathy, Dilated; | 2008 |
Cardiac and hemodynamic effects of intravenous dofetilide in patients with heart failure.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Double-Blind Method; Electrocardiography; Female; H | 2001 |
66 other studies available for amiodarone and Electrocardiogram QT Prolonged
| Article | Year |
|---|---|
Amiodarone in patients with left bundle branch block: how to assess the QT interval?
Topics: Amiodarone; Bundle-Branch Block; Electrocardiography; Female; Heart Rate; Humans; Long QT Syndrome; | 2021 |
Torsade de pointes in initiating hemodialysis: a case report.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Long QT Syndrome; Renal Dialysis; Torsades | 2020 |
Effects of amiodarone on rodent ventricular cardiomyocytes: Novel perspectives from a cellular model of Long QT Syndrome Type 3.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cardiac Conduction System Disease; Dose-Response Relati | 2020 |
Naturally occurring torsades de pointes and QT interval prolongation in a domestic cat.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Cat Diseases; Cats; Electrocardiography; Long QT Syndro | 2021 |
QTc interval prolongation in critically ill patients: Prevalence, risk factors and associated medications.
Topics: Adult; Aged; Amiodarone; Clopidogrel; Critical Illness; Cross-Sectional Studies; Electrocardiography | 2018 |
Real-world implications of QT prolongation in patients receiving voriconazole and amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antifungal Agents; Drug Interactions; Female; Humans; Long | 2019 |
Ventricular ectopy and QTc-interval prolongation associated with dronedarone therapy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Electrocardiography, Amb | 2013 |
Serious QT interval prolongation with ranolazine and amiodarone.
Topics: Acetanilides; Aged; Amiodarone; Electrocardiography; Female; Humans; Long QT Syndrome; Piperazines; | 2014 |
Intermittent QT prolongation induced by short-term oral amiodarone therapy.
Topics: Administration, Oral; Adult; Amiodarone; Anti-Arrhythmia Agents; Brugada Syndrome; Cardiac Conductio | 2014 |
Prolongation of a prolonged QT: a case of an undiagnosed congenital long QT syndrome.
Topics: Adult; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; Long QT Syndrome; Po | 2014 |
Cardiac arrest and electrical storm due to recurrent torsades de pointes caused by concomitant clarithromycin, cotrimoxazole and amiodarone treatment.
Topics: Amiodarone; Anti-Arrhythmia Agents; Clarithromycin; Drug Therapy, Combination; Electrocardiography; | 2014 |
Proarrhythmic effect of 'Reverse Mode Switch' in a patient with dilated cardiomyopathy and drug-induced long QTc interval.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiac Resynchronization Therapy; Cardiac Resynchronizati | 2015 |
[Paroxysmal atrial fibrillation well controlled. Why the sudden patient syncope?].
Topics: Amiodarone; Atrial Fibrillation; Clopidogrel; Coronary Disease; Diagnosis, Differential; Drug Therap | 2015 |
[Combination therapy with fluconazole and other QTc-prolonging drugs increase the QTc interval].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antifungal Agents; Clarithromycin; | 2015 |
Prevalence and Risk Factors Associated with Use of QT-Prolonging Drugs in Hospitalized Older People.
Topics: Aged; Aged, 80 and over; Amiodarone; Atrial Fibrillation; Electrocardiography; Female; Hospitalizati | 2016 |
Effects of concomitant amiodarone and haloperidol on Q-Tc interval prolongation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Antipsychotic Agents; Drug Therapy, Combination; Electroca | 2008 |
Ciprofloxacin induced acquired long QT syndrome in a patient under class III antiarrhythmic therapy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents; Atrial Fibrillation; Ciprofloxacin; | 2009 |
Amiodarone for pediatric resuscitation: a word of caution.
Topics: Amiodarone; Anti-Arrhythmia Agents; Child; Contraindications; Diagnostic Errors; Electrocardiography | 2009 |
Interpreting data about prolongation of the Q-Tc interval induced by amiodarone and haloperidol.
Topics: Amiodarone; Data Interpretation, Statistical; Drug Therapy, Combination; Haloperidol; Humans; Long Q | 2009 |
Case report: drug interaction between tacrolimus and amiodarone with QT prolongation.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Coronary Artery Bypass; Diabetic Neph | 2010 |
[Flecainide poisoning].
Topics: Aged; Amiodarone; Atrial Fibrillation; Cholecystectomy; Cholecystitis; Electrocardiography; Emergenc | 2010 |
[Unexpected complication following esophageal variceal hemorrhage - Case 2/2011].
Topics: Amiodarone; Anti-Bacterial Agents; Ciprofloxacin; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inh | 2011 |
Torsade de pointes induced by citalopram and amiodarone.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Citalopram; Depressive D | 2011 |
Acquired long QT interval: a case series of multifactorial QT prolongation.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Long QT Syndrome; Male; Middle Aged | 2011 |
Electrophysiologic profile of dronedarone on the ventricular level: beneficial effect on postrepolarization refractoriness in the presence of rapid phase 3 repolarization.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Dronedarone; Electrocardiography; El | 2012 |
Acute inhibition of the Na(+)/Ca(2+) exchanger reduces proarrhythmia in an experimental model of chronic heart failure.
Topics: Action Potentials; Amiodarone; Animals; Anti-Arrhythmia Agents; Disease Models, Animal; Heart; Heart | 2012 |
Did you know? Why amiodarone requires diligent monitoring?
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Drug Monitoring; Female; Humans; Long Q | 2011 |
A neonate with long QT syndrome, refractory ventricular arrhythmias, and lidocaine toxicity.
Topics: Amiodarone; Anesthetics, Local; Anti-Arrhythmia Agents; Cardiac Pacing, Artificial; DNA Mutational A | 2012 |
Common variation in the NOS1AP gene is associated with drug-induced QT prolongation and ventricular arrhythmia.
Topics: Adaptor Proteins, Signal Transducing; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Ag | 2012 |
Optimal QT/JT interval assessment in patients with complete bundle branch block.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Bundle-Branch Block; Case-Control Studi | 2012 |
Drug-drug interactions contributing to QT prolongation in cardiac intensive care units.
Topics: Amiodarone; Anti-Anxiety Agents; Anti-Arrhythmia Agents; Anti-Infective Agents; Antipsychotic Agents | 2013 |
Amiodarone and acetazolamide for the treatment of genetically confirmed severe Andersen syndrome.
Topics: Acetazolamide; Adolescent; Amiodarone; Anti-Arrhythmia Agents; Anticonvulsants; Child; Drug Therapy, | 2002 |
Characterization of the non-linear rate-dependency of QT interval in humans.
Topics: Action Potentials; Adolescent; Adult; Aged; Amiodarone; Animals; Anti-Arrhythmia Agents; Disease Mod | 2003 |
Torsades de pointes and QT prolongation due to a combination of loratadine and amiodarone.
Topics: Aged; Amiodarone; Anti-Allergic Agents; Anti-Arrhythmia Agents; Electrocardiography; Female; Humans; | 2003 |
Effect of amiodarone on the descending limb of the T wave.
Topics: Adolescent; Adult; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Electrocard | 2003 |
Comparison of the in vitro electrophysiologic and proarrhythmic effects of amiodarone and sotalol in a rabbit model of acute atrioventricular block.
Topics: Action Potentials; Administration, Oral; Amiodarone; Animals; Disease Models, Animal; Drug Administr | 2004 |
QT interval prolongation and torsades de pointes due to a coadministration of metronidazole and amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Anti-Infective Agents; Atrial Fibrillation; Drug Interacti | 2005 |
QT interval prolongation and Torsades de Pointes in a patient receiving zolpidem and amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Electric Countershock; Female; Heart Co | 2006 |
Letter from Konstantinos P. Letsas et al. - invited editorial comment.
Topics: Amiodarone; Anti-Arrhythmia Agents; Drug Interactions; Humans; Hypnotics and Sedatives; Long QT Synd | 2006 |
[Polymorphic ventricular tachycardia in acute myocardial infarction without ST elevation in a patient with thrombocytopenia].
Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Coronary Angiography; Electrocardiography; | 2006 |
What to treat-the fast or the slow rhythm?
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Atrial Premature Complexes; Catheter Ablati | 2006 |
Acquired long QT syndrome: Unequal regression of Amiodarone-induced repolarization lengthening.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Electrocardiography; Female; Follow-Up Studie | 2008 |
Further evidence of inherited long QT syndrome gene mutations in antiarrhythmic drug-associated torsades de pointes.
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; DNA Mutational Analysis; Electrocardiog | 2007 |
[Long QT syndrome induced by cordaron and quinidine].
Topics: Amiodarone; Anemia, Hemolytic; Anti-Arrhythmia Agents; Female; Humans; Hypertension; Long QT Syndrom | 2007 |
Augmentation of late sodium current unmasks the proarrhythmic effects of amiodarone.
Topics: Action Potentials; Amiodarone; Animals; Arrhythmias, Cardiac; Cnidarian Venoms; Dose-Response Relati | 2008 |
Amiodarone-associated macroscopic T-wave alternans and torsade de pointes unmasking the inherited long QT syndrome.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Bradycardia; Electrocardiography; Humans; L | 2008 |
Isoproterenol enhancement of I(Ks) current in amiodarone-induced long QT syndrome.
Topics: Aged, 80 and over; Amiodarone; Dose-Response Relationship, Drug; Humans; Isoproterenol; Long QT Synd | 2009 |
[Amiodarone therapy after sotalol-induced torsade de pointes: prolonged QT interval and QT dispersion in differentiation of pro-arrhythmic effects].
Topics: Aged; Amiodarone; Electrocardiography, Ambulatory; Female; Follow-Up Studies; Humans; Long QT Syndro | 1994 |
Adaptation of the QT interval to heart rate changes in isolated perfused guinea pig heart: influence of amiodarone and D-sotalol.
Topics: Adaptation, Physiological; Amiodarone; Animals; Anti-Arrhythmia Agents; Electric Stimulation; Electr | 1997 |
Acquired long QT syndromes and the risk of proarrhythmia.
Topics: Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Humans; Long QT Syndrome | 2000 |
Amiodarone-induced AV block and ventricular standstill. A forme fruste of an idiopathic long QT syndrome.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Drug Therapy, Combination; Electrocardiography; Electrophy | 2000 |
Torsade de pointes induced by intravenous and long-term oral amiodarone therapy in a patient with dilated cardiomyopathy.
Topics: Administration, Oral; Aged; Amiodarone; Anti-Arrhythmia Agents; Cardiomyopathy, Dilated; Electrocard | 2001 |
Amiodarone-induced long QT and polymorphic ventricular tachycardia.
Topics: Action Potentials; Age Factors; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Cathe | 2001 |
Quinolone-induced QT interval prolongation: a not-so-unexpected class effect.
Topics: Amiodarone; Animals; Anti-Infective Agents; Drug Combinations; Drug Interactions; Enzyme Inhibitors; | 2001 |
Chronic amiodarone evokes no torsade de pointes arrhythmias despite QT lengthening in an animal model of acquired long-QT syndrome.
Topics: Action Potentials; Administration, Oral; Amiodarone; Anesthesia; Animals; Anti-Arrhythmia Agents; Ar | 2001 |
Amiodarone-induced giant T wave alternans hastens proarrhythmic response.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dose-Response Relationship, Drug; Ele | 2002 |
Sudden cardiac death while taking amiodarone therapy: the role of abnormal repolarization.
Topics: Adult; Amiodarone; Electrocardiography; Electrophysiology; Heart Arrest; Humans; Long QT Syndrome; M | 1991 |
Effective management of long Q-T syndrome with amiodarone.
Topics: Amiodarone; Child; Electrocardiography; Humans; Long QT Syndrome; Male; Seizures | 1990 |
Acute treatment of torsades de pointes with amiodarone: proarrhythmic and antiarrhythmic association of QT prolongation.
Topics: Amiodarone; Arrhythmias, Cardiac; Electrocardiography; Humans; Long QT Syndrome; Male; Middle Aged; | 1990 |
Monophasic action potential studies in human subjects with prolonged ventricular repolarization and long QT syndromes.
Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Bradycardia; Cardiac Complexes, Premature | 1985 |
Delayed ventricular repolarization as an anti-arrhythmic principle.
Topics: Adrenergic beta-Antagonists; Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Bund | 1985 |
Amiodarone in patients with previous drug-mediated torsade de pointes. Long-term safety and efficacy.
Topics: Adult; Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Cardiac | 1989 |
Use of intravenous amiodarone for emergency treatment of life-threatening ventricular arrhythmias.
Topics: Amiodarone; Arrhythmias, Cardiac; Bradycardia; Cardiac Pacing, Artificial; Electrocardiography; Emer | 1988 |
Torsade de pointes during loading with amiodarone.
Topics: Administration, Oral; Amiodarone; Atrial Flutter; Cardiac Pacing, Artificial; Dose-Response Relation | 1987 |
Amiodarone-induced torsades de pointes.
Topics: Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Atrial Fibrillation; Atrial Flutter; Benzofurans; Dru | 1986 |
Evaluation of amiodarone therapy in the treatment of drug-resistant cardiac arrhythmias: long term follow-up.
Topics: Adolescent; Adult; Aged; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Drug Resistance; Electrocard | 1985 |