Page last updated: 2024-10-22

amiodarone and Drug Hypersensitivity

amiodarone has been researched along with Drug Hypersensitivity in 27 studies

Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.

Drug Hypersensitivity: Immunologically mediated adverse reactions to medicinal substances used legally or illegally.

Research Excerpts

ExcerptRelevanceReference
"Amiodarone hydrochloride-induced thrombocytopenia seems to be an additional side effect in the course of amiodarone treatment."7.67Amiodarone-induced thrombocytopenia. ( Agmon, J; Ben-Sasson, E; Fuchs, J; Rotenberg, Z; Weinberger, I, 1987)
"Twenty patients with photodermatoses [actinic prurigo (n = 6), hydroa vacciniforme (n = 4), idiopathic solar urticaria (n = 1), amiodarone-induced photosensitivity (n = 1) and a range of cutaneous porphyrias (n = 8)] were treated with a 'hardening' course of narrow-band ultraviolet B (TL-01) phototherapy in springtime."5.08Narrow-band UVB (TL-01) phototherapy: an effective preventative treatment for the photodermatoses. ( Collins, P; Ferguson, J, 1995)
"Amiodarone hydrochloride-induced thrombocytopenia seems to be an additional side effect in the course of amiodarone treatment."3.67Amiodarone-induced thrombocytopenia. ( Agmon, J; Ben-Sasson, E; Fuchs, J; Rotenberg, Z; Weinberger, I, 1987)
"Iodine is an essential human nutrient found in the thyroid gland."2.72Iodine allergy: Common misperceptions. ( Choi, A; Kapusnik-Uner, J; Schmitz, J; Wulf, NR, 2021)
"Immediate drug hypersensitivity or food hypersensitivity is assessed by immediate-reading skin tests while non-immediate drug hypersensitivity is investigated by delayed-reading skin testing."2.52[Allergy to iodinated drugs and to foods rich in iodine: Iodine is not the allergenic determinant]. ( Dewachter, P; Mouton-Faivre, C, 2015)
"Diagnosis of extrinsic allergic alveolitis is based on the association of clinical, radiological, functional, immunological criteria and bronchoalveolar lavage fluid analysis."2.41[Diffuse infiltrative lung diseases due to allergy and iatrogenic causes]. ( Dalphin, JC, 2000)
"Amiodarone is a class III antiarrhythmic agent frequently used in the management of atrial fibrillation after cardiac surgery."1.34Hypersensitivity reaction to amiodarone in a patient with a previous reaction to an iodinated radiocontrast agent. ( Stafford, L, 2007)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-199012 (44.44)18.7374
1990's4 (14.81)18.2507
2000's5 (18.52)29.6817
2010's3 (11.11)24.3611
2020's3 (11.11)2.80

Authors

AuthorsStudies
Vella, A1
Bjørklund, G1
Chirumbolo, S1
Fernando, SL1
Li, J1
Jain, A1
Weir, C1
Boyle, T1
El-Khatib, L1
Alrayes, H1
Sallam, O1
Elbanna, A1
Wulf, NR1
Schmitz, J1
Choi, A1
Kapusnik-Uner, J1
Dewachter, P1
Mouton-Faivre, C1
Snider, M1
Boyd, M1
Carnes, CA1
Lakshmanadoss, U1
Lindsley, J1
Glick, D1
Twilley, CH1
Lewin, JJ1
Marine, JE1
Brouse, SD1
Phillips, SM1
Stafford, L1
Venet, A2
Caubarrere, I2
Bonan, G2
Pannier, R1
Arlet, P1
Carré, P1
Bismuth, JM1
Larregain-Fournier, D1
Le Tallec, Y1
Akoun, GM2
Gauthier-Rahman, S2
Milleron, BJ1
Perrot, JY1
Mayaud, CM1
Collins, P1
Ferguson, J2
Wilson, BD1
Lippmann, ML1
Tidwell, BH1
Jones, JS1
Dalphin, JC1
Lloveras, J1
Masramon, J1
Aubia, J1
Llorach, M1
Kuhlman, JE1
George, JL1
Chrysanthopoulos, C1
Siablis, D1
Kounis, NG1
Ruiz Manzano, J1
Morera Prat, J1
Weinberger, I1
Rotenberg, Z1
Fuchs, J1
Ben-Sasson, E1
Agmon, J1
Chebat, J1
Uzzan, D1
Gilbert, J1
Beaufils, H1

Reviews

5 reviews available for amiodarone and Drug Hypersensitivity

ArticleYear
Iodine allergy: Common misperceptions.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2021, 04-22, Volume: 78, Issue:9

    Topics: Amiodarone; Contrast Media; Drug Hypersensitivity; Humans; Iodine; Thyroxine

2021
[Allergy to iodinated drugs and to foods rich in iodine: Iodine is not the allergenic determinant].
    Presse medicale (Paris, France : 1983), 2015, Volume: 44, Issue:11

    Topics: Allergens; Amiodarone; Anaphylaxis; Animals; Anti-Infective Agents, Local; Biomarkers; Contrast Medi

2015
[Diffuse infiltrative lung diseases due to allergy and iatrogenic causes].
    La Revue du praticien, 2000, Nov-01, Volume: 50, Issue:17

    Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Anti-Arrhythmia Agents; Bronchoalveolar Lavage Fluid; Cr

2000
The role of chest computed tomography in the diagnosis of drug-related reactions.
    Journal of thoracic imaging, 1991, Volume: 6, Issue:1

    Topics: Amiodarone; Bleomycin; Drug Hypersensitivity; Humans; Immunoblastic Lymphadenopathy; Lung; Lung Dise

1991
[Pulmonary toxicity caused by amiodarone].
    Medicina clinica, 1986, Jul-12, Volume: 87, Issue:6

    Topics: Amiodarone; Benzofurans; Dose-Response Relationship, Drug; Drug Hypersensitivity; Humans; Lung Disea

1986

Trials

1 trial available for amiodarone and Drug Hypersensitivity

ArticleYear
Narrow-band UVB (TL-01) phototherapy: an effective preventative treatment for the photodermatoses.
    The British journal of dermatology, 1995, Volume: 132, Issue:6

    Topics: Adolescent; Adult; Amiodarone; Child; Drug Hypersensitivity; Female; Humans; Hydroa Vacciniforme; Ma

1995

Other Studies

21 other studies available for amiodarone and Drug Hypersensitivity

ArticleYear
Basophil Activation Test in Amiodarone Hypersensitivity and Non-IgE-Mediated Allergy.
    Journal of investigational allergology & clinical immunology, 2019, Volume: 29, Issue:5

    Topics: Amiodarone; Basophil Degranulation Test; Basophils; Drug Hypersensitivity; Humans; Hypersensitivity

2019
Mixed drug reaction to amiodarone characterized by sequential immediate, immune complex, and delayed hypersensitivity.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2020, Volume: 125, Issue:1

    Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Drug Hypersensitivity; H

2020
Quinidine hypersensitivity: a side effect of a forgotten antiarrhythmic.
    BMJ case reports, 2020, Aug-24, Volume: 13, Issue:8

    Topics: Acute Disease; Aged; Amiodarone; Anti-Arrhythmia Agents; Chemical and Drug Induced Liver Injury; Dru

2020
Amiodarone use in patients with documented hypersensitivity to intravenous contrast dye.
    The Annals of pharmacotherapy, 2008, Volume: 42, Issue:9

    Topics: Amiodarone; Anti-Arrhythmia Agents; Contrast Media; Drug Hypersensitivity; Humans; Male; Middle Aged

2008
Drug-induced photosensitivity.
    Prescrire international, 2009, Volume: 18, Issue:103

    Topics: Aminolevulinic Acid; Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Ca

2009
Incidence of amiodarone hypersensitivity in patients with previous allergy to iodine or iodinated contrast agents.
    Pharmacotherapy, 2012, Volume: 32, Issue:7

    Topics: Academic Medical Centers; Administration, Oral; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia

2012
Amiodarone use in patients with documented allergy to iodine-containing compounds.
    Pharmacotherapy, 2005, Volume: 25, Issue:3

    Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Contrast Media; Drug Hypersensitivity; Humans; Iodine; Mal

2005
Hypersensitivity reaction to amiodarone in a patient with a previous reaction to an iodinated radiocontrast agent.
    The Annals of pharmacotherapy, 2007, Volume: 41, Issue:7

    Topics: Amiodarone; Contrast Media; Drug Hypersensitivity; Humans; Iodine; Iohexol; Male; Middle Aged; Secon

2007
Five cases of immune-mediated amiodarone pneumonitis.
    Lancet (London, England), 1984, Apr-28, Volume: 1, Issue:8383

    Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Benzofurans; Drug Hypersensitivity; Humans

1984
Drug induced lung disease.
    European journal of respiratory diseases. Supplement, 1983, Volume: 126

    Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Antineoplastic Agents; Asthma; Drug Hypersensitivity; Hu

1983
[Amiodarone: a new cause of hypersensitivity pneumopathy?].
    Revue de pneumologie clinique, 1984, Volume: 40, Issue:3

    Topics: Aged; Amiodarone; Benzofurans; Drug Hypersensitivity; Female; Follow-Up Studies; Humans; Pneumonia;

1984
Amiodarone pneumonitis: three further cases with a review of published reports.
    Thorax, 1984, Volume: 39, Issue:10

    Topics: Alveolitis, Extrinsic Allergic; Amiodarone; Benzofurans; Drug Hypersensitivity; Humans

1984
Amiodarone-induced hypersensitivity pneumonitis. Evidence of an immunological cell-mediated mechanism.
    Chest, 1984, Volume: 85, Issue:1

    Topics: Aged; Alveolitis, Extrinsic Allergic; Amiodarone; Benzofurans; Cell Migration Inhibition; Drug Hyper

1984
Amiodarone pulmonary toxicity in the rat is associated with increased lavage immunoglobulin and alveolar macrophages primed for increased interleukin-1 secretion.
    American journal of respiratory cell and molecular biology, 1993, Volume: 9, Issue:3

    Topics: Amiodarone; Analysis of Variance; Animals; Bronchoalveolar Lavage Fluid; Drug Hypersensitivity; Enzy

1993
Amiodarone-induced pulmonary hypersensitivity.
    The Annals of pharmacotherapy, 1997, Volume: 31, Issue:12

    Topics: Aged; Amiodarone; Drug Hypersensitivity; Humans; Male; Respiratory Hypersensitivity

1997
Amiodarone, metoclopramide, and renal failure.
    Lancet (London, England), 1979, May-05, Volume: 1, Issue:8123

    Topics: Amiodarone; Benzofurans; Drug Hypersensitivity; Dystonia Musculorum Deformans; Female; Humans; Metoc

1979
[Corneal, conjunctival and lacrimal changes (excluding dry eye)].
    Bulletin des societes d'ophtalmologie de France, 1985, Volume: Spec No

    Topics: Adrenal Cortex Hormones; Amiodarone; Anesthetics, Local; Anti-Bacterial Agents; Antineoplastic Agent

1985
Amiodarone: a study of cutaneous photosensitivity.
    British journal of clinical practice. Supplement, 1986, Volume: 44

    Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Child; Drug Hypersensitivity; Female; Humans; Male

1986
Amiodarone-induced recurrent allergic pneumonitis.
    Annals of allergy, 1988, Volume: 60, Issue:2

    Topics: Amiodarone; Drug Hypersensitivity; Female; Humans; Male; Middle Aged; Pneumonia; Respiratory Hyperse

1988
Amiodarone-induced thrombocytopenia.
    Archives of internal medicine, 1987, Volume: 147, Issue:4

    Topics: Aged; Amiodarone; Drug Hypersensitivity; Humans; Hypersensitivity, Delayed; Lymphocyte Activation; M

1987
[Pneumopathies caused by hypersensitivity to amiodarone and associated nephropathies. Study by alveolar lavage].
    Annales de medecine interne, 1985, Volume: 136, Issue:4

    Topics: Acute Kidney Injury; Aged; Amiodarone; Benzofurans; Drug Hypersensitivity; Female; Humans; Kidney Di

1985