amiodarone has been researched along with Demyelinating Diseases in 6 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Demyelinating Diseases: Diseases characterized by loss or dysfunction of myelin in the central or peripheral nervous system.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 67 years-old man under amiodarone treatment for thirteen months due to a cardiac arrhythmia developed a mixed sensory-motor neuropathy." | 3.68 | [Peripheral neuropathy possibly caused by amiodarone therapy]. ( de Carvalho, FB; Oliveira Júnior, W; Oliveira, LF, 1991) |
| "Although the pathogenesis of demyelination induced by these drugs remain largely obscure, the recent in vivo and in vitro studies have implicated the involvement of metabolic abnormalities and impaired autophagy in Schwann cells and immune system disorders in the disruption of neuron-Schwann cell contact and interactions." | 2.61 | Drug-Induced Demyelinating Neuropathies. ( Niimi, N; Sango, K; Takaku, S; Yako, H, 2019) |
| "Amiodarone was injected endoneurially at increasing doses into the exposed tibial nerve of rats to study its electrophysiologic and pathologic effects on peripheral nerve fibers." | 1.28 | Amiodarone-induced experimental acute neuropathy in rats. ( Barbieri, F; Battaglia, F; Caruso, G; Crispi, F; Greco, P; Nucciotti, R; Ragno, M; Santoro, L, 1992) |
| "Amiodarone has been used for the last 20 years, initially as antianginal and then as antiarrhythmic agent." | 1.28 | [Optic neuropathy caused by amiodarone]. ( Ferreiro, JL; Isern Longares, JA; Ramón Moya, AF, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niimi, N | 2 |
| Takaku, S | 2 |
| Yako, H | 2 |
| Sango, K | 2 |
| Tsukamoto, M | 1 |
| Yamauchi, J | 1 |
| Kawakami, E | 1 |
| Yanagisawa, H | 1 |
| Watabe, K | 1 |
| Utsunomiya, K | 1 |
| Kaeser, HE | 1 |
| Ulrich, J | 1 |
| Wüthrich, R | 1 |
| Santoro, L | 1 |
| Barbieri, F | 1 |
| Nucciotti, R | 1 |
| Battaglia, F | 1 |
| Crispi, F | 1 |
| Ragno, M | 1 |
| Greco, P | 1 |
| Caruso, G | 1 |
| Oliveira, LF | 1 |
| Oliveira Júnior, W | 1 |
| de Carvalho, FB | 1 |
| Ferreiro, JL | 1 |
| Isern Longares, JA | 1 |
| Ramón Moya, AF | 1 |
1 review available for amiodarone and Demyelinating Diseases
| Article | Year |
|---|---|
Drug-Induced Demyelinating Neuropathies.
Topics: Amiodarone; Axons; Demyelinating Diseases; Dichloroacetic Acid; Drug-Related Side Effects and Advers | 2019 |
5 other studies available for amiodarone and Demyelinating Diseases
| Article | Year |
|---|---|
Involvement of oxidative stress and impaired lysosomal degradation in amiodarone-induced schwannopathy.
Topics: Amiodarone; Animals; Cells, Cultured; Demyelinating Diseases; Enzyme Inhibitors; Female; Ganglia, Sp | 2016 |
Amiodarone neuropathy (author's transl).
Topics: Amiodarone; Angina Pectoris; Benzofurans; Demyelinating Diseases; Humans; Male; Middle Aged; Nervous | 1976 |
Amiodarone-induced experimental acute neuropathy in rats.
Topics: Amiodarone; Animals; Axons; Demyelinating Diseases; Male; Microscopy, Electron; Neural Conduction; P | 1992 |
[Peripheral neuropathy possibly caused by amiodarone therapy].
Topics: Aged; Amiodarone; Arrhythmias, Cardiac; Demyelinating Diseases; Humans; Male; Peripheral Nervous Sys | 1991 |
[Optic neuropathy caused by amiodarone].
Topics: Amiodarone; Animals; Cardiac Complexes, Premature; Demyelinating Diseases; Humans; Male; Middle Aged | 1990 |