amiodarone has been researched along with Cranial Nerve II Diseases in 44 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study aimed to describe a case of optic neuropathy after substitution of amiodarone with dronedarone for treatment of atrial fibrillation." | 7.96 | Case Report: Presumed Optic Neuropathy after Amiodarone and then Dronedarone for Treatment of Atrial Fibrillation. ( Maharshak, I; Paul, M; Steiner, H, 2020) |
| "This study aimed to describe a case of optic neuropathy after substitution of amiodarone with dronedarone for treatment of atrial fibrillation." | 3.96 | Case Report: Presumed Optic Neuropathy after Amiodarone and then Dronedarone for Treatment of Atrial Fibrillation. ( Maharshak, I; Paul, M; Steiner, H, 2020) |
| "To report clinical features of amiodarone-induced optic neuropathy and outline the differentiation of amiodarone optic neuropathy from nonarteritic anterior ischemic optic neuropathy." | 3.70 | Features of amiodarone-induced optic neuropathy. ( Fraunfelder, FT; Macaluso, DC; Shults, WT, 1999) |
| "The authors present an account on an uncommon case when damage of visual functions of a patient were due to two independent cause: amiodarone neuropathy of the optic nerve (ANO) and an intracranial tumour-a craniopharyngioma." | 3.69 | [Amiodarone neuropathy of the optic nerve from the viewpoint of the neuro-ophthalmologist]. ( Hobza, V; Jirásková, N; Rozsíval, P, 1996) |
| "Damage of the optic nerve (optic neuropathy) may be caused, apart from other reasons, by an adverse drug effect." | 2.44 | [Adverse effect optic neuropathy]. ( Martini, BC, 2008) |
| "The optic nerve is quite vulnerable to the toxic effect of drugs." | 2.44 | [Toxicity of recent and less recent drugs on the optic nerve. Does Viagra cause blindness?]. ( Cordonnier, M, 2007) |
| "The term optic neuropathy is used to describe optic nerve damage caused by any of four main etiologies: ischemic, hereditary, nutritional and toxic." | 2.44 | Drug-induced optic neuropathies. ( Fraunfelder, FW; Lloyd, MJ, 2007) |
| "Treatment with amiodarone should be discontinued after exclusion of life-threatening situations by a cardiologist, as soon as the first changes of the optic disc occur." | 2.42 | [Amiodarone treatment and visual prognosis]. ( Schmidt, D, 2003) |
| " Although several agents have ocular effects, amiodarone is the most widely recognized for producing adverse effects in the eyes." | 2.40 | Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations. ( Pollak, PT, 1999) |
| " After ruling out intracranial hypertension, arteritic ischemic optic neuropathy, non-arteritic, and inflammatory bilateral papilledema, the diagnosis was toxic optic neuropathy." | 1.51 | [Amiodarone-induced optic neuropathy: A rare side effect]. ( Ambrosi, P; Arcani, R; Arnould, T; Chagny, M; Daumas, A; Gayet, S; Gobin, N; Micallef, J; Pellerey, M; Rouby, F; Scapin, J; Villani, P, 2019) |
| "Amiodarone is a commonly prescribed and one of the most effective anti-arrhythmic drugs available." | 1.39 | Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone. ( Falck, A; Hautala, N; Hurskainen, M; Kervinen, M, 2013) |
| "Amiodarone was discontinued after discussion with the patient's cardiologist." | 1.32 | Amiodarone induced optic neuropathy. ( Castillo, I; Foroozan, R; Nagra, PK; Savino, PJ; Sergott, RC, 2003) |
| "Amiodarone therapy was then discontinued, but there was no considerable improvement and after 6 weeks visual loss occurred in the left eye as well." | 1.31 | [First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?]. ( Gerke, E; Uebermuth, CA, 2002) |
| "Optic neuropathy has been reported to occur during antiarrhythmic therapy with amiodarone." | 1.31 | [Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy]. ( Gerling, J; Hansen, LL; Leifert, D, 2000) |
| "Amiodarone has been used for the last 20 years, initially as antianginal and then as antiarrhythmic agent." | 1.28 | [Optic neuropathy caused by amiodarone]. ( Ferreiro, JL; Isern Longares, JA; Ramón Moya, AF, 1990) |
| "Amiodarone has been implicated in the pathogenesis of optic neuropathy in several cases." | 1.27 | Optic nerve ultrastructure following amiodarone therapy. ( Mansour, AM; O'Grady, R; Puklin, JE, 1988) |
| "Appearance of optic neuropathy is probably a relative indication for discontinuing the use of the drug, in the hopes of avoiding bilateral involvement or perhaps recovering vision." | 1.27 | Optic neuropathy and amiodarone therapy. ( Feiner, LA; Fraunfelder, FT; Kazmier, FJ; Stricker, BH; Younge, BR, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (11.36) | 18.7374 |
| 1990's | 5 (11.36) | 18.2507 |
| 2000's | 19 (43.18) | 29.6817 |
| 2010's | 11 (25.00) | 24.3611 |
| 2020's | 4 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Mitchell, R | 1 |
| Chacko, J | 1 |
| Bayrakçeken, K | 1 |
| Ucgul, RK | 1 |
| Coban, T | 1 |
| Yazıcı, G | 1 |
| Suleyman, H | 1 |
| Arcani, R | 1 |
| Pellerey, M | 1 |
| Rouby, F | 1 |
| Gobin, N | 1 |
| Scapin, J | 1 |
| Chagny, M | 1 |
| Arnould, T | 1 |
| Ambrosi, P | 1 |
| Gayet, S | 1 |
| Micallef, J | 1 |
| Villani, P | 1 |
| Daumas, A | 1 |
| Maharshak, I | 1 |
| Paul, M | 1 |
| Steiner, H | 1 |
| Tan, Y | 1 |
| Sia, P | 1 |
| Simon, S | 1 |
| Kervinen, M | 1 |
| Falck, A | 1 |
| Hurskainen, M | 1 |
| Hautala, N | 1 |
| Chassang, B | 1 |
| Bonnin, N | 1 |
| Moisset, X | 1 |
| Citron, B | 1 |
| Clavelou, P | 1 |
| Chiambaretta, F | 1 |
| Mindel, JS | 3 |
| Cheng, HC | 1 |
| Yeh, HJ | 1 |
| Huang, N | 1 |
| Chou, YJ | 1 |
| Yen, MY | 1 |
| Wang, AG | 1 |
| Bagiella, E | 1 |
| Knudsen, A | 1 |
| Wasinska-Borowiec, W | 1 |
| Aghdam, KA | 1 |
| Saari, JM | 1 |
| Grzybowski, A | 1 |
| Martini, BC | 1 |
| Passman, RS | 1 |
| Bennett, CL | 1 |
| Purpura, JM | 1 |
| Kapur, R | 1 |
| Johnson, LN | 2 |
| Raisch, DW | 1 |
| West, DP | 1 |
| Edwards, BJ | 1 |
| Belknap, SM | 1 |
| Liebling, DB | 1 |
| Fisher, MJ | 1 |
| Samaras, AT | 1 |
| Jones, LG | 1 |
| Tulas, KM | 1 |
| McKoy, JM | 1 |
| Ciechanowski, PP | 1 |
| Töteberg-Harms, M | 1 |
| Stürmer, J | 1 |
| Kunz, M | 1 |
| Landau, K | 1 |
| Sturm, V | 1 |
| Selvaraj, V | 1 |
| Johnson, KG | 1 |
| Uebermuth, CA | 1 |
| Gerke, E | 1 |
| Nagra, PK | 1 |
| Foroozan, R | 1 |
| Savino, PJ | 1 |
| Castillo, I | 1 |
| Sergott, RC | 1 |
| Schmidt, D | 1 |
| Domingues, MF | 1 |
| Barros, H | 1 |
| Falcão-Reis, FM | 1 |
| Chen, D | 1 |
| Hedges, TR | 1 |
| Krohel, GB | 1 |
| Thomas, ER | 1 |
| Clement, CI | 1 |
| Myers, P | 1 |
| Tan, KP | 1 |
| Turdumambetova, G | 1 |
| Bredehorn, T | 1 |
| Duncker, GI | 1 |
| Murphy, MA | 1 |
| Murphy, JF | 1 |
| Purvin, V | 1 |
| Kawasaki, A | 1 |
| Borruat, FX | 1 |
| Fraunfelder, FW | 2 |
| Fraunfelder, FT | 3 |
| Cordonnier, M | 1 |
| Lloyd, MJ | 1 |
| Jirásková, N | 1 |
| Rozsíval, P | 1 |
| Hobza, V | 1 |
| Seemongal-Dass, RR | 1 |
| Spencer, SR | 1 |
| Macaluso, DC | 1 |
| Shults, WT | 1 |
| Pollak, PT | 1 |
| Speicher, MA | 1 |
| Goldman, MH | 1 |
| Chrousos, GA | 1 |
| Leifert, D | 1 |
| Hansen, LL | 1 |
| Gerling, J | 1 |
| Polak, BC | 1 |
| Tutein Nolthenius, PA | 1 |
| Rietveld, E | 1 |
| Verslegers, W | 1 |
| De Deyn, PP | 1 |
| Ferreiro, JL | 1 |
| Isern Longares, JA | 1 |
| Ramón Moya, AF | 1 |
| Nazarian, SM | 1 |
| Jay, WM | 1 |
| Younge, BR | 2 |
| Mansour, AM | 1 |
| Puklin, JE | 1 |
| O'Grady, R | 1 |
| Dewachter, A | 1 |
| Lievens, H | 1 |
| Feiner, LA | 1 |
| Kazmier, FJ | 1 |
| Stricker, BH | 1 |
14 reviews available for amiodarone and Cranial Nerve II Diseases
| Article | Year |
|---|---|
Clinical and Mechanistic Review of Amiodarone-Associated Optic Neuropathy.
Topics: Amiodarone; Humans; Insulin-Like Growth Factor I; Optic Nerve; Optic Nerve Diseases; Optic Neuropath | 2022 |
An Updated Review on the Most Common Agents Causing Toxic Optic Neuropathies.
Topics: Amiodarone; Erythropoietin; Ethambutol; Humans; Linezolid; Methanol; Optic Nerve Diseases; Phosphodi | 2017 |
[Adverse effect optic neuropathy].
Topics: Acetamides; Amiodarone; Anti-Arrhythmia Agents; Anti-Bacterial Agents; Antitubercular Agents; Drug-R | 2008 |
Amiodarone-associated optic neuropathy: a critical review.
Topics: Amiodarone; Anti-Arrhythmia Agents; Blindness; Humans; Optic Nerve Diseases | 2012 |
Dronedarone-induced optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Dronedarone; Humans; Male; Optic Nerve Diseases | 2013 |
[Amiodarone treatment and visual prognosis].
Topics: Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Femal | 2003 |
Amiodarone optic neuropathy--review.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Optic Nerve Diseases | 2003 |
The clinical spectrum of amiodarone-associated optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Dose-Response Relationship, Drug; Female; Humans; Male; Mi | 2004 |
Bilateral optic neuropathy due to amiodarone with recurrence.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Male; Optic Nerve Diseases; R | 2005 |
[Ocular side-effects associated with amiodarone therapy].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Corneal Opacity; Dose-Response Re | 2005 |
Amiodarone and optic neuropathy: the heart of the matter.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Optic Nerve Diseases; Registries | 2005 |
[Toxicity of recent and less recent drugs on the optic nerve. Does Viagra cause blindness?].
Topics: Acetamides; Amiodarone; Blindness; Ethambutol; Humans; Immunosuppressive Agents; Interferon-alpha; L | 2007 |
Drug-induced optic neuropathies.
Topics: Acetamides; Adverse Drug Reaction Reporting Systems; Amiodarone; Anti-Arrhythmia Agents; Anti-Infect | 2007 |
Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Corneal Opacity; Diagnosis, Differential; Humans; Lung | 1999 |
30 other studies available for amiodarone and Cranial Nerve II Diseases
| Article | Year |
|---|---|
Effect of adenosine triphosphate on amiodarone-induced optic neuropathy in rats: biochemical and histopathological evaluation.
Topics: Adenosine Triphosphate; Amiodarone; Animals; Glutathione; Optic Nerve; Optic Nerve Diseases; Rats; R | 2023 |
[Amiodarone-induced optic neuropathy: A rare side effect].
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Female; Humans; Iatrogenic Disease; Optic Ner | 2019 |
Case Report: Presumed Optic Neuropathy after Amiodarone and then Dronedarone for Treatment of Atrial Fibrillation.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Dronedarone; Drug Substi | 2020 |
Optic neuropathy secondary to perhexiline and amiodarone.
Topics: Aged; Amiodarone; Fluorescein Angiography; Humans; Male; Optic Nerve Diseases; Perhexiline; Recurren | 2021 |
Bilateral optic neuropathy and permanent loss of vision after treatment with amiodarone.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Blindness; Female; Humans; Optic Nerve Diseases; Papillede | 2013 |
Two cases of bilateral amiodarone-associated optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Middle Aged; Optic Nerve Diseases | 2014 |
Absence of amiodarone-associated optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Incidence; Optic Nerve Diseases; United States | 2014 |
Amiodarone-Associated Optic Neuropathy: A Nationwide Study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Databases, Factual; | 2015 |
Re: Cheng et al.: Amiodarone-associated optic neuropathy: a nationwide study (Ophthalmology 2015;122:2553-9).
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Optic Nerve Diseases; Optic Neuritis | 2016 |
Short-term treatment with oral amiodarone resulting in bilateral optic neuropathy and permanent blindness.
Topics: Administration, Oral; Aftercare; Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Blin | 2017 |
Amiodarone and optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Humans; Incidence; Optic Nerve Diseases; Un | 2008 |
Bilateral optic neuropathy after short-term treatment with intravenous amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Anti-Inflammatory Agents; Blindness; Humans; Injections, Intrave | 2012 |
[First unilateral, later bilateral optic neuropathy. Amiodarone as the cause?].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blindness; Dose-Response Relationshi | 2002 |
Amiodarone induced optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Color Perception; Fluorescein Angiography; Humans; Male; M | 2003 |
Amiodarone and optic neuropathy.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Case-Control Studies; Contrast Sensitivity; Evoked Potenti | 2004 |
Optic neuropathy in patients using amiodarone.
Topics: Aged; Aged, 80 and over; Amiodarone; Diagnosis, Differential; Female; Humans; Male; Middle Aged; Opt | 2006 |
Scientific challenges in postmarketing surveillance of ocular adverse drug reactions.
Topics: Adverse Drug Reaction Reporting Systems; Amiodarone; Chloramphenicol; Databases, Factual; Drug-Relat | 2007 |
[Amiodarone neuropathy of the optic nerve from the viewpoint of the neuro-ophthalmologist].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Craniopharyngioma; Humans; Male; Optic Nerve Diseases; Opt | 1996 |
Bilateral optic neuropathy linked with amiodarone.
Topics: Amiodarone; Anti-Arrhythmia Agents; Follow-Up Studies; Humans; Male; Middle Aged; Optic Nerve Diseas | 1998 |
Features of amiodarone-induced optic neuropathy.
Topics: Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Fundus Oculi; Humans; Optic Nerve; Opti | 1999 |
Amiodarone optic neuropathy without disc edema.
Topics: Amiodarone; Anti-Arrhythmia Agents; Humans; Male; Middle Aged; Optic Nerve; Optic Nerve Diseases; Pa | 2000 |
[Amiodarone-associated optic neuropathy: an independent syndrome? Three patients with bilateral optic neuropathy].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Humans; Male; Middle Aged; Optic | 2000 |
[Visual impairment due to optic neuropathy in 2 patients on amiodarone therapy, i.e. ethambutol and isoniazide].
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Female; Humans; Male; Middle Aged | 2001 |
[Visual impairment due to optic neuropathy in 2 patients on amiodarone, and ethambutol and isoniazide therapy, respectively].
Topics: Amiodarone; Anti-Arrhythmia Agents; Antitubercular Agents; Diagnosis, Differential; Ethambutol; Fema | 2001 |
[Optic neuropathy caused by amiodarone].
Topics: Amiodarone; Animals; Cardiac Complexes, Premature; Demyelinating Diseases; Humans; Male; Middle Aged | 1990 |
Bilateral optic neuropathy associated with amiodarone therapy.
Topics: Amiodarone; Atrial Fibrillation; Humans; Male; Middle Aged; Ophthalmoscopy; Optic Atrophy; Optic Ner | 1988 |
Amiodarone optic neuropathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Disease Susceptibility; Humans; Optic Nerve Diseases | 1988 |
Optic nerve ultrastructure following amiodarone therapy.
Topics: Amiodarone; Choroid Neoplasms; Humans; Male; Melanoma; Microscopy, Electron; Middle Aged; Optic Nerv | 1988 |
Amiodarone and optic neuropathy.
Topics: Amiodarone; Female; Fluorescein Angiography; Humans; Male; Middle Aged; Optic Nerve Diseases; Vision | 1988 |
Optic neuropathy and amiodarone therapy.
Topics: Aged; Amiodarone; Female; Humans; Male; Middle Aged; Optic Nerve Diseases; Tachycardia; Vision Tests | 1987 |