amiodarone has been researched along with Corneal Opacity in 11 studies
Amiodarone: An antianginal and class III antiarrhythmic drug. It increases the duration of ventricular and atrial muscle action by inhibiting POTASSIUM CHANNELS and VOLTAGE-GATED SODIUM CHANNELS. There is a resulting decrease in heart rate and in vascular resistance.
amiodarone : A member of the class of 1-benzofurans that is 1-benzofuran substituted by a butyl group at position 2 and a 4-[2-(diethylamino)ethoxy]-3,5-diiodobenzoyl group at position 3. It is a cardiovascular drug used for the treatment of cardiac dysrhythmias.
Corneal Opacity: Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Although several agents have ocular effects, amiodarone is the most widely recognized for producing adverse effects in the eyes." | 2.40 | Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations. ( Pollak, PT, 1999) |
| " The patient reported complete compliance with using amiodarone daily, with no recent changes in dosage or formulation." | 1.38 | A significant drug-drug interaction detected through corneal examination: resolution of cornea verticillata while using amiodarone. ( Bunya, VY; Dunaief, JL; Mehta, S; Orlin, SE; Sulewski, ME, 2012) |
| "under AM therapy the initial arrhythmias were no longer detectable in 41% of the patients." | 1.27 | [Antiarrhythmic effect and side effects of amiodarone]. ( Haddad, R; Konrad, K; Mainitz, M; Mlczoch, J; Probst, P; Scheibelhofer, W; Weber, H; Weissel, M, 1984) |
| "No amiodarone was present in the tears at low serum concentrations but a rapid increase in tear concentrations was seen at serum values above 1." | 1.27 | Amiodarone induced cornea verticillata. ( Andreasen, F; Bjerregaard, P; Nielsen, CE, 1983) |
| "Amiodarone hydrochloride is an antiarrhythmic drug which produces a keratopathy and anterior subcapsular lens opacities that are usually asymptomatic." | 1.27 | Amiodarone keratopathy and lens opacities. ( Dolan, BJ; Flach, AJ; Peterson, JS, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 2 (18.18) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Luu, K | 1 |
| Welch, RJ | 1 |
| Yiu, G | 1 |
| Mehta, S | 1 |
| Bunya, VY | 1 |
| Orlin, SE | 1 |
| Sulewski, ME | 1 |
| Dunaief, JL | 1 |
| Turdumambetova, G | 1 |
| Bredehorn, T | 1 |
| Duncker, GI | 1 |
| Bhatt, PR | 1 |
| Ramaesh, K | 1 |
| Orlando, RG | 1 |
| Dangel, ME | 1 |
| Schaal, SF | 1 |
| Weber, H | 1 |
| Weissel, M | 1 |
| Haddad, R | 1 |
| Scheibelhofer, W | 1 |
| Konrad, K | 1 |
| Mlczoch, J | 1 |
| Probst, P | 1 |
| Mainitz, M | 1 |
| Fraunfelder, FT | 1 |
| Meyer, SM | 1 |
| Nielsen, CE | 1 |
| Andreasen, F | 1 |
| Bjerregaard, P | 1 |
| Goldblum, D | 1 |
| Garweg, JG | 1 |
| Pollak, PT | 1 |
| Dolan, BJ | 1 |
| Flach, AJ | 1 |
| Peterson, JS | 1 |
2 reviews available for amiodarone and Corneal Opacity
| Article | Year |
|---|---|
[Ocular side-effects associated with amiodarone therapy].
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Corneal Opacity; Dose-Response Re | 2005 |
Clinical organ toxicity of antiarrhythmic compounds: ocular and pulmonary manifestations.
Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Corneal Opacity; Diagnosis, Differential; Humans; Lung | 1999 |
9 other studies available for amiodarone and Corneal Opacity
| Article | Year |
|---|---|
Man in His 90s With a History of Tachycardia and Abnormal Findings on Slitlamp Examination of the Cornea.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Corneal Opacity; Epithel | 2020 |
A significant drug-drug interaction detected through corneal examination: resolution of cornea verticillata while using amiodarone.
Topics: Aged, 80 and over; Amiodarone; Anti-Arrhythmia Agents; Antibiotics, Antitubercular; Corneal Opacity; | 2012 |
Unilateral amiodarone keratopathy: occlusive contact lens spares development in the contralateral eye.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Atrial Fibrillation; Contact Lenses; Cornea; Corneal Opaci | 2007 |
Clinical experience and grading of amiodarone keratopathy.
Topics: Aged; Amiodarone; Benzofurans; Cornea; Corneal Diseases; Corneal Opacity; Dose-Response Relationship | 1984 |
[Antiarrhythmic effect and side effects of amiodarone].
Topics: Adult; Aged; Airway Resistance; Amiodarone; Arrhythmias, Cardiac; Benzofurans; Cornea; Corneal Opaci | 1984 |
Amiodarone keratopathy.
Topics: Amiodarone; Arrhythmias, Cardiac; Benzofurans; Corneal Opacity; Humans | 1984 |
Amiodarone induced cornea verticillata.
Topics: Adolescent; Adult; Aged; Amiodarone; Benzofurans; Corneal Opacity; Female; Humans; Male; Middle Aged | 1983 |
Amiodarone-induced cornea verticillata.
Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Corneal Diseases; Corneal Opacity; Humans; Male | 1998 |
Amiodarone keratopathy and lens opacities.
Topics: Adult; Aged; Amiodarone; Benzofurans; Cataract; Corneal Opacity; Follow-Up Studies; Humans; Middle A | 1985 |